KR101774206B1 - 유도된 다능성 줄기 세포의 효율적인 확립 방법 - Google Patents
유도된 다능성 줄기 세포의 효율적인 확립 방법 Download PDFInfo
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- KR101774206B1 KR101774206B1 KR1020127004663A KR20127004663A KR101774206B1 KR 101774206 B1 KR101774206 B1 KR 101774206B1 KR 1020127004663 A KR1020127004663 A KR 1020127004663A KR 20127004663 A KR20127004663 A KR 20127004663A KR 101774206 B1 KR101774206 B1 KR 101774206B1
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2501/608—Lin28
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1361—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from dental pulp or dental follicle stem cells
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- C12N2800/00—Nucleic acids vectors
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- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
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- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23240209P | 2009-08-07 | 2009-08-07 | |
| US61/232,402 | 2009-08-07 | ||
| US30730610P | 2010-02-23 | 2010-02-23 | |
| US61/307,306 | 2010-02-23 | ||
| PCT/JP2010/063733 WO2011016588A1 (en) | 2009-08-07 | 2010-08-06 | Method of efficiently establishing induced pluripotent stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20120047968A KR20120047968A (ko) | 2012-05-14 |
| KR101774206B1 true KR101774206B1 (ko) | 2017-09-04 |
Family
ID=43544479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020127004663A Active KR101774206B1 (ko) | 2009-08-07 | 2010-08-06 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8900871B2 (enExample) |
| EP (1) | EP2462225B1 (enExample) |
| JP (1) | JP5376478B2 (enExample) |
| KR (1) | KR101774206B1 (enExample) |
| CN (1) | CN102625837B (enExample) |
| AU (1) | AU2010279913B2 (enExample) |
| CA (1) | CA2770412C (enExample) |
| ES (1) | ES2726766T3 (enExample) |
| SG (2) | SG178197A1 (enExample) |
| WO (1) | WO2011016588A1 (enExample) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
| US20110061118A1 (en) * | 2008-03-17 | 2011-03-10 | Helmholtz Zentrum Munchen | Vectors and methods for generating vector-free induced pluripotent stem (ips) cells using site-specific recombination |
| ES2690554T3 (es) | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| KR101606943B1 (ko) | 2008-06-27 | 2016-03-28 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 유도된 다능성 줄기 세포의 효율적인 확립 방법 |
| EP2307539B1 (en) * | 2008-07-30 | 2014-11-19 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| ES2645869T3 (es) | 2008-12-17 | 2017-12-11 | The Scripps Research Institute | Generación y mantenimiento de células madre |
| KR101764100B1 (ko) | 2009-02-27 | 2017-08-02 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 신규한 핵 재프로그래밍 물질 |
| WO2011016588A1 (en) | 2009-08-07 | 2011-02-10 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| WO2011037270A1 (en) * | 2009-09-24 | 2011-03-31 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| ES2638464T3 (es) * | 2009-10-16 | 2017-10-20 | The Scripps Research Institute | Inducción de células pluripotentes |
| ES2539487T3 (es) | 2009-11-04 | 2015-07-01 | Cellular Dynamics International, Inc. | Reprogramación episómica con compuestos químicos |
| JP5765746B2 (ja) | 2010-02-16 | 2015-08-19 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| WO2011119942A1 (en) * | 2010-03-25 | 2011-09-29 | Vistagen Therapeutics, Inc. | Induction of ips cells using transient episomal vectors |
| AU2011235212B2 (en) | 2010-03-31 | 2014-07-31 | The Scripps Research Institute | Reprogramming cells |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| US8691574B2 (en) | 2010-06-15 | 2014-04-08 | Cellular Dynamics International, Inc. | Generation of induced pluripotent stem cells from small volumes of peripheral blood |
| JP5794588B2 (ja) | 2010-09-14 | 2015-10-14 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| US20130295064A1 (en) * | 2010-10-14 | 2013-11-07 | University Of Central Florida Research Foundation, Inc. | Cardiac induced pluripotent stem cells and methods of use in repair and regeneration of myocardium |
| CN106893692B (zh) | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| US9758765B2 (en) | 2011-04-08 | 2017-09-12 | Osaka University | Modified laminin and use thereof |
| PL2694642T3 (pl) | 2011-04-08 | 2019-01-31 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Sposób odmładzania komórek |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| WO2013022022A1 (ja) * | 2011-08-08 | 2013-02-14 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| WO2013074916A1 (en) | 2011-11-18 | 2013-05-23 | Board Of Regents, The University Of Texas System | Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla |
| US20130157368A1 (en) * | 2011-12-20 | 2013-06-20 | Advanced Technologies And Regenerative Medicine, Llc | Induced pluripotent stem cells prepared from human kidney-derived cells |
| US20130157365A1 (en) * | 2011-12-20 | 2013-06-20 | Advanced Technologies And Regenerative Medicine, Llc | Induced pluripotent stem cells from human umbilical cord tissue-derived cells |
| US10155929B2 (en) * | 2012-05-13 | 2018-12-18 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| US10119150B2 (en) * | 2012-05-13 | 2018-11-06 | Allele Biotechnology & Pharmaceuticals, Inc. | Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA |
| EP2853592B1 (en) | 2012-05-23 | 2019-02-20 | Kyoto University | Highly efficient method for establishing artificial pluripotent stem cell |
| CN102965393B (zh) * | 2012-11-06 | 2015-08-26 | 上海交通大学 | 人诱导多能干细胞的制备方法及其用途 |
| US20150368713A1 (en) | 2013-02-01 | 2015-12-24 | THE UNITED STATES OF AMERICAN, as represented by the Secretary, Department of Health and Human Serv | METHOD FOR GENERATING RETINAL PIGMENT EPITHELIUM (RPE) CELLS FROM INDUCED PLURIPOTENT STEM CELLS (IPSCs) |
| WO2014192312A1 (ja) * | 2013-05-31 | 2014-12-04 | 国立大学法人 東京医科歯科大学 | 正常な内向きのカリウム電流特性を有するiPS細胞由来心筋モデル細胞 |
| WO2015006725A2 (en) | 2013-07-12 | 2015-01-15 | Cedars-Sinai Medical Center | Generation of induced pluripotent stem cells from normal human mammary epithelial cells |
| CN103571794B (zh) * | 2013-07-19 | 2016-01-20 | 中国医学科学院血液病医院(血液学研究所) | 一种抑制PUMA功能改善iPS细胞建立功效的方法 |
| CN103740756B (zh) * | 2013-12-25 | 2015-08-05 | 中国农业大学 | 一种可调控删除的非病毒游离载体及其构建方法 |
| CN103725710B (zh) * | 2013-12-25 | 2015-10-28 | 北京济福霖生物技术有限公司 | 一种可自我删除游离载体及其应用 |
| CN103740757B (zh) * | 2014-01-21 | 2016-04-20 | 中国科学院生物物理研究所 | 一种利用重编程制备猪神经干细胞的方法 |
| CN104830906B (zh) | 2014-02-12 | 2018-09-04 | 北京维通达生物技术有限公司 | 一种重编程获得功能性人肝脏实质细胞的方法 |
| SG10201807292YA (en) | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| US10927384B2 (en) | 2014-04-09 | 2021-02-23 | Dna Twopointo Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| CA2945393C (en) * | 2014-04-24 | 2021-03-23 | Board Of Regents, The University Of Texas System | Application of induced pluripotent stem cells to generate adoptive cell therapy products |
| EP3152295B1 (en) * | 2014-06-05 | 2020-07-29 | Cedars-Sinai Medical Center | A novel and efficient method for reprogramming immortalized lymphoblastoid cell lines to induced pluripotent stem cells |
| WO2016117139A1 (ja) * | 2015-01-20 | 2016-07-28 | タカラバイオ株式会社 | 神経系細胞の製造方法 |
| EP3250679B1 (en) * | 2015-01-30 | 2020-08-19 | Centre National de la Recherche Scientifique (CNRS) | Reprogramming method for producing induced pluripotent stem cells (ipsc) |
| ES2884838T3 (es) | 2015-04-06 | 2021-12-13 | Univ Leland Stanford Junior | ARN guía químicamente modificados para la regulación génica mediada por CRISPR/CAS |
| EP3332020B1 (en) | 2015-08-07 | 2023-12-20 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Method of determining cellular protein homeostasis |
| ES2970537T3 (es) | 2015-09-08 | 2024-05-29 | Us Health | Método para la diferenciación reproducible de células epiteliales del pigmento retiniano de calidad clínica |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| EP3974524A1 (en) | 2015-10-08 | 2022-03-30 | Dna Twopointo Inc. | Dna vectors, transposons and transposases for eukaryotic genome modification |
| AU2016338680B2 (en) | 2015-10-16 | 2022-11-17 | Fate Therapeutics, Inc. | Platform for the induction and maintenance of ground state pluripotency |
| US10865381B2 (en) | 2015-10-20 | 2020-12-15 | FUJIFILM Cellular Dynamics, Inc. | Multi-lineage hematopoietic precursor cell production by genetic programming |
| US11898163B2 (en) | 2016-04-22 | 2024-02-13 | Kyoto University | Method for producing dopaminergic neuron progenitor cell |
| ES2904882T3 (es) * | 2016-04-29 | 2022-04-06 | Virogin Biotech Canada Ltd | Vectores de HSV con replicación mejorada en células cancerosas |
| GB201608944D0 (en) | 2016-05-20 | 2016-07-06 | Ospedale San Raffaele And Fond Telethon | Gene Tharapy |
| US11572545B2 (en) | 2016-06-16 | 2023-02-07 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US10221395B2 (en) | 2016-06-16 | 2019-03-05 | Cedars-Sinai Medical Center | Efficient method for reprogramming blood to induced pluripotent stem cells |
| US20180030478A1 (en) | 2016-07-01 | 2018-02-01 | Research Development Foundation | Elimination of proliferating cells from stem cell-derived grafts |
| WO2018026723A1 (en) | 2016-08-01 | 2018-02-08 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Human induced pluripotent stem cells for high efficiency genetic engineering |
| WO2018049168A1 (en) | 2016-09-09 | 2018-03-15 | The Board Of Trustees Of The Leland Stanford Junior University | High-throughput precision genome editing |
| BR112019006910A2 (pt) * | 2016-10-05 | 2019-07-02 | Fujifilm Cellular Dynamics Inc | métodos para diferenciação dirigida de células-tronco pluripotentes para células imunes homozigóticas de hla |
| ES3009605T3 (en) | 2016-10-05 | 2025-03-27 | Fujifilm Cellular Dynamics Inc | Generating mature lineages from induced pluripotent stem cells with mecp2 disruption |
| WO2018089515A1 (en) | 2016-11-09 | 2018-05-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | 3d vascularized human ocular tissue for cell therapy and drug discovery |
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| AU2010279913B2 (en) | 2016-04-28 |
| EP2462225B1 (en) | 2019-03-06 |
| US9404124B2 (en) | 2016-08-02 |
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