KR101686692B1 - 마이크로니들 어레이 - Google Patents

마이크로니들 어레이 Download PDF

Info

Publication number
KR101686692B1
KR101686692B1 KR1020117027674A KR20117027674A KR101686692B1 KR 101686692 B1 KR101686692 B1 KR 101686692B1 KR 1020117027674 A KR1020117027674 A KR 1020117027674A KR 20117027674 A KR20117027674 A KR 20117027674A KR 101686692 B1 KR101686692 B1 KR 101686692B1
Authority
KR
South Korea
Prior art keywords
polylactic acid
micro needle
needle
average molecular
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020117027674A
Other languages
English (en)
Korean (ko)
Other versions
KR20120037910A (ko
Inventor
다카아키 데라하라
세이지 도쿠모토
아키라 다무라
유미코 야마다
Original Assignee
히사미쓰 세이야꾸 가부시키가이샤
도판 인사츠 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 히사미쓰 세이야꾸 가부시키가이샤, 도판 인사츠 가부시키가이샤 filed Critical 히사미쓰 세이야꾸 가부시키가이샤
Publication of KR20120037910A publication Critical patent/KR20120037910A/ko
Application granted granted Critical
Publication of KR101686692B1 publication Critical patent/KR101686692B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A61B5/1405—Devices for taking blood samples
    • A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150427—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A61B5/150511—Details of construction of shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
KR1020117027674A 2009-07-23 2010-07-15 마이크로니들 어레이 Active KR101686692B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2009-172525 2009-07-23
JP2009172525 2009-07-23
PCT/JP2010/062008 WO2011010605A1 (ja) 2009-07-23 2010-07-15 マイクロニードルアレイ

Publications (2)

Publication Number Publication Date
KR20120037910A KR20120037910A (ko) 2012-04-20
KR101686692B1 true KR101686692B1 (ko) 2016-12-14

Family

ID=43499078

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117027674A Active KR101686692B1 (ko) 2009-07-23 2010-07-15 마이크로니들 어레이

Country Status (8)

Country Link
US (1) US8696638B2 (https=)
EP (1) EP2457592B1 (https=)
JP (1) JP5620911B2 (https=)
KR (1) KR101686692B1 (https=)
CN (1) CN102470179A (https=)
ES (1) ES2826882T3 (https=)
IN (1) IN2012DN00906A (https=)
WO (1) WO2011010605A1 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2008241470B2 (en) 2007-04-16 2013-11-07 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
ES2634667T3 (es) * 2009-04-24 2017-09-28 Corium International, Inc. Métodos para fabricar conjuntos de microproyección
WO2010143689A1 (ja) * 2009-06-10 2010-12-16 久光製薬株式会社 マイクロニードルデバイス
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
US9498611B2 (en) 2011-10-06 2016-11-22 Hisamitsu Pharmaceutical Co., Inc. Applicator
WO2013053022A1 (en) 2011-10-12 2013-04-18 The University Of Queensland Delivery device
JP2013162861A (ja) * 2012-02-10 2013-08-22 Bioserentack Co Ltd 細胞間液モニター用マイクロニードル
EP4112112A1 (en) 2012-05-01 2023-01-04 University of Pittsburgh - Of the Commonwealth System of Higher Education Tip-loaded microneedle arrays for transdermal insertion
JP6865524B2 (ja) 2012-12-21 2021-04-28 コリウム， インコーポレイテッド 治療剤を送達するためのマイクロアレイおよび使用方法
CA3130120A1 (en) 2013-03-12 2014-10-09 Corium, Inc. Microprojection applicators
RU2711567C2 (ru) 2013-03-15 2020-01-17 Кориум, ИНК. Микрочип для доставки лекарственного средства и способы его использования
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
JP6689187B2 (ja) 2013-03-15 2020-04-28 コリウム， インコーポレイテッド 複数の衝突微小突起アプリケータおよび使用方法
KR101712413B1 (ko) * 2013-03-22 2017-03-06 쓰리엠 이노베이티브 프로퍼티즈 컴파니 카운터 조립체를 포함하는 마이크로니들 어플리케이터
EP3188714A1 (en) 2014-09-04 2017-07-12 Corium International, Inc. Microstructure array, methods of making, and methods of use
JP6001043B2 (ja) * 2014-12-15 2016-10-05 日本写真印刷株式会社 マイクロニードルアレイ製造装置及びマイクロニードルアレイの製造方法並びにマイクロニードルアレイを有する製品
AU2016214968B2 (en) * 2015-02-02 2021-02-25 Vaxxas Pty Limited Microprojection array applicator and method
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
JP5852280B1 (ja) * 2015-03-23 2016-02-03 コスメディ製薬株式会社 マイクロニードルおよびその製造
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3320945B1 (en) * 2015-07-07 2019-09-18 Toppan Printing Co., Ltd. Percutaneous administration device
CN105126242A (zh) * 2015-07-26 2015-12-09 北京化工大学 一种便于抗生素皮试的高分子涂层微针贴片及其制备方法
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
KR101610598B1 (ko) * 2015-09-21 2016-04-07 비엔엘바이오테크 주식회사 잇몸 굴곡에 맞게 유연하며 치과용 물질 전달을 위한 마이크로 니들 및 그 제작방법
EP3355981B1 (en) 2015-09-28 2025-11-19 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
CN107569238A (zh) * 2016-07-04 2018-01-12 中山大学 一种粘贴式烟囱型微针阵列及其制造方法
EP3606760B1 (en) 2017-03-31 2023-09-27 Vaxxas Pty Limited Device and method for coating surfaces
WO2018208222A1 (en) * 2017-05-10 2018-11-15 Chee Yen Lim Pyramidal microneedles with enhanced drug loading capacity and method for manufacturing
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
US11464957B2 (en) 2017-08-04 2022-10-11 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (MAP)
US11785943B2 (en) * 2017-09-22 2023-10-17 Uchicago Argonne, Llc Tunable nanotextured materials
US11247896B2 (en) 2018-07-31 2022-02-15 Uchicago Argonne, Llc Localized functionalization of nanotextured surfaces
CN113874065A (zh) 2019-05-16 2021-12-31 联邦高等教育系统匹兹堡大学 用于皮肤和非皮肤药物递送的具有底切特征的微针阵列
CN114901104B (zh) * 2019-12-25 2025-02-25 太阳星光齿磨公司 牙刷
CN112569465B (zh) * 2020-12-29 2022-07-19 华东理工大学 一种微针贴片的制备方法
JPWO2024005176A1 (https=) * 2022-06-30 2024-01-04
CN115227976A (zh) * 2022-07-20 2022-10-25 上海交通大学 一种控温射频微针系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060127465A1 (en) * 2003-06-10 2006-06-15 Shinya Maenosono Pad base for transdermal administration and needle
JP2009502261A (ja) 2005-07-25 2009-01-29 ナノテクノロジー ビクトリア ピーティーワイ リミテッド マイクロアレイデバイス
JP2009072271A (ja) * 2007-09-19 2009-04-09 Toppan Printing Co Ltd 針状体および針状体の製造方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2747306B2 (ja) * 1988-12-24 1998-05-06 富士通株式会社 半導体装置
AU722574B2 (en) 1996-12-20 2000-08-10 Alza Corporation Device and method for enhancing transdermal agent flux
JPH11286439A (ja) 1998-04-01 1999-10-19 Senju Pharmaceut Co Ltd 生分解性ポリマー型薬物放出システム
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
JP2005021678A (ja) 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
JP2005021677A (ja) 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベース、及び注射針
KR20060127394A (ko) 2003-10-31 2006-12-12 알자 코포레이션 경피 백신 전달 시스템 및 방법
JP2007519446A (ja) 2004-01-09 2007-07-19 アルザ・コーポレーシヨン 振動支援型の経皮的な薬剤の送達法および系
JP4832082B2 (ja) 2004-02-03 2011-12-07 久光製薬株式会社 経皮薬物投与装置用インタフェース
EP1790375A4 (en) 2004-08-12 2009-06-17 Hisamitsu Pharmaceutical Co TRANSDERMAL MEDICINE ADMINISTRATION WITH MICRONADEL
WO2006075689A1 (ja) 2005-01-14 2006-07-20 Fujikura Ltd. 医薬物運搬用器具とその製造方法
WO2006075716A1 (ja) 2005-01-14 2006-07-20 Fujikura Ltd. 医薬物運搬用器具とその製造方法
WO2006121110A1 (ja) 2005-05-13 2006-11-16 Hisamitsu Pharmaceutical Co., Inc. 医薬物運搬用器具およびその製造方法
JP2006341089A (ja) 2005-05-13 2006-12-21 Fujikura Ltd 医薬物運搬用器具およびその製造方法
JP5000866B2 (ja) 2005-08-01 2012-08-15 久光製薬株式会社 生体無毒性医薬物運搬用器具
ATE532553T1 (de) 2006-02-10 2011-11-15 Hisamitsu Pharmaceutical Co Transdermales arzneiverabreichungsgerät mit mikronadeln
JP4908893B2 (ja) 2006-03-30 2012-04-04 久光製薬株式会社 医薬物運搬用器具とその製造方法及び医薬物運搬用器具製造用金型の製造方法
WO2007116959A1 (ja) 2006-04-07 2007-10-18 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルデバイスおよびマイクロニードル付き経皮薬物投与装置
JP5241517B2 (ja) 2007-02-06 2013-07-17 久光製薬株式会社 アレルギー診断用マイクロニードルデバイス
JP4978245B2 (ja) * 2007-03-08 2012-07-18 凸版印刷株式会社 針状体、針状体製造方法および薬物輸送デバイス
US8771781B2 (en) 2007-05-15 2014-07-08 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle
JP5194632B2 (ja) 2007-08-15 2013-05-08 凸版印刷株式会社 針状体の製造方法
WO2009051147A1 (ja) 2007-10-18 2009-04-23 Hisamitsu Pharmaceutical Co., Inc. マイクロニードルデバイス

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060127465A1 (en) * 2003-06-10 2006-06-15 Shinya Maenosono Pad base for transdermal administration and needle
JP2009502261A (ja) 2005-07-25 2009-01-29 ナノテクノロジー ビクトリア ピーティーワイ リミテッド マイクロアレイデバイス
JP2009072271A (ja) * 2007-09-19 2009-04-09 Toppan Printing Co Ltd 針状体および針状体の製造方法

Also Published As

Publication number Publication date
US8696638B2 (en) 2014-04-15
EP2457592B1 (en) 2020-09-16
US20120136312A1 (en) 2012-05-31
JPWO2011010605A1 (ja) 2012-12-27
ES2826882T3 (es) 2021-05-19
EP2457592A4 (en) 2013-01-02
IN2012DN00906A (https=) 2015-04-03
WO2011010605A1 (ja) 2011-01-27
CN102470179A (zh) 2012-05-23
EP2457592A1 (en) 2012-05-30
KR20120037910A (ko) 2012-04-20
JP5620911B2 (ja) 2014-11-05

Similar Documents

Publication Publication Date Title
KR101686692B1 (ko) 마이크로니들 어레이
KR101759354B1 (ko) 마이크로니들 디바이스
KR101634836B1 (ko) 마이크로 니들 디바이스
JP5419702B2 (ja) マイクロニードルデバイス
JP5709530B2 (ja) マイクロニードルデバイス
JP5050130B2 (ja) マイクロニードル
Umeyor et al. Biomimetic microneedles: exploring the recent advances on a microfabricated system for precision delivery of drugs, peptides, and proteins
EP2957297B1 (en) Microneedle-coating composition and microneedle device
JP7090299B2 (ja) ドネペジルを含有するマイクロニードル経皮パッチ
EP2127693A1 (en) Process for producing microneedle of thermosensitive substance
EP4159266A1 (en) High-performance micro-needle array
EP3220997A1 (en) Micro-needle sheet for reducing wrinkles and method of forming
KR101621945B1 (ko) 이층 구조의 나노 크기 구멍을 가진 마이크로니들 및 이의 제조 방법
KR102127123B1 (ko) 마이크로구조체 제조방법
EP4183410A1 (en) Preventive agent for japanese encephalitis and japanese encephalitis vaccine

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

P22-X000 Classification modified

St.27 status event code: A-2-2-P10-P22-nap-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

FPAY Annual fee payment

Payment date: 20191101

Year of fee payment: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 20201109

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

FPAY Annual fee payment

Payment date: 20211108

Year of fee payment: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

FPAY Annual fee payment

Payment date: 20221107

Year of fee payment: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 10