IN2012DN00906A - - Google Patents

Info

Publication number
IN2012DN00906A
IN2012DN00906A IN906DEN2012A IN2012DN00906A IN 2012DN00906 A IN2012DN00906 A IN 2012DN00906A IN 906DEN2012 A IN906DEN2012 A IN 906DEN2012A IN 2012DN00906 A IN2012DN00906 A IN 2012DN00906A
Authority
IN
India
Prior art keywords
weight
average molecular
performance
molecular weight
microneedle array
Prior art date
Application number
Inventor
Terahara Takaaki
Tokumoto Seiji
Tamura Akira
Yamada Yumiko
Original Assignee
Hisamitsu Pharmaceutical Co
Toppan Printing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co, Toppan Printing Co Ltd filed Critical Hisamitsu Pharmaceutical Co
Publication of IN2012DN00906A publication Critical patent/IN2012DN00906A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A61B5/1405—Devices for taking blood samples
    • A61B5/1411—Devices for taking blood samples by percutaneous method, e.g. by lancet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
    • A61B5/150427—Specific tip design, e.g. for improved penetration characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A61B5/150511—Details of construction of shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150969—Low-profile devices which resemble patches or plasters, e.g. also allowing collection of blood samples for testing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Relations between crystallinity and performance of a biodegradable resin, between weight-average molecular weight and strength thereof, and between weight-average molecular weight and performance thereof were clarified. As a result thereof, when a microneedle array was provided with microneedles containing noncrystalline polylactic acid which had a weight-average molecular weight of 40,000 to 100,000, it was possible to obtain a microneedle array which could maintain its functional performance.
IN906DEN2012 2009-07-23 2010-07-15 IN2012DN00906A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009172525 2009-07-23
PCT/JP2010/062008 WO2011010605A1 (en) 2009-07-23 2010-07-15 Microneedle array

Publications (1)

Publication Number Publication Date
IN2012DN00906A true IN2012DN00906A (en) 2015-04-03

Family

ID=43499078

Family Applications (1)

Application Number Title Priority Date Filing Date
IN906DEN2012 IN2012DN00906A (en) 2009-07-23 2010-07-15

Country Status (8)

Country Link
US (1) US8696638B2 (en)
EP (1) EP2457592B1 (en)
JP (1) JP5620911B2 (en)
KR (1) KR101686692B1 (en)
CN (1) CN102470179A (en)
ES (1) ES2826882T3 (en)
IN (1) IN2012DN00906A (en)
WO (1) WO2011010605A1 (en)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
ES2820335T3 (en) 2007-04-16 2021-04-20 Corium Inc Solvent Cast Microneedle Arrays Containing Active Agent
EP2429627B1 (en) * 2009-04-24 2017-06-14 Corium International, Inc. Methods for manufacturing microprojection arrays
KR101759354B1 (en) 2009-06-10 2017-07-18 히사미쓰 세이야꾸 가부시키가이샤 Microneedle device
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
WO2011140274A2 (en) 2010-05-04 2011-11-10 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
EP2764887B1 (en) 2011-10-06 2020-12-02 Hisamitsu Pharmaceutical Co., Inc. Applicator
EP2765927B1 (en) * 2011-10-12 2021-02-24 Vaxxas Pty Limited Delivery device
JP2013162861A (en) * 2012-02-10 2013-08-22 Bioserentack Co Ltd Microneedle for monitoring intercellular fluid
EP2841147A4 (en) 2012-05-01 2016-04-13 Univ Pittsburgh MICRO-NEEDLES NETWORKS WITH CHARGED END FOR TRANSDERMAL INSERTION
BR112015014969B1 (en) 2012-12-21 2021-12-07 Corium, Inc MICROSTRUCTURE APPARATUS AND METHOD OF MANUFACTURING A MICROSTRUCTURE APPARATUS
EP2968887B1 (en) 2013-03-12 2022-05-04 Corium, Inc. Microprojection applicators
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
ES2939317T3 (en) 2013-03-15 2023-04-20 Corium Pharma Solutions Inc Multi-impact micro-spray applicators
BR112015022625B1 (en) 2013-03-15 2023-01-31 Corium, Inc MICROSTRUCTURE DEVICE FOR DELIVERY OF THERAPEUTIC AGENT
WO2014153447A2 (en) * 2013-03-22 2014-09-25 3M Innovative Properties Company Microneedle applicator comprising a counter assembly
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
JP6001043B2 (en) * 2014-12-15 2016-10-05 日本写真印刷株式会社 Microneedle array manufacturing apparatus, microneedle array manufacturing method, and product having microneedle array
US11147954B2 (en) * 2015-02-02 2021-10-19 Vaxxas Pty Limited Microprojection array applicator and method
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
JP5852280B1 (en) * 2015-03-23 2016-02-03 コスメディ製薬株式会社 Microneedle and its manufacture
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017006958A1 (en) * 2015-07-07 2017-01-12 凸版印刷株式会社 Percutaneous administration device
CN105126242A (en) * 2015-07-26 2015-12-09 北京化工大学 Polymer coating microneedle patch convenient for antibiotic skin testing and preparation method thereof
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
KR101610598B1 (en) * 2015-09-21 2016-04-07 비엔엘바이오테크 주식회사 FLEXIBLE MICRONEEDLE FOR DENTAL MATERIAL DELIVERY AND THE MANUFACTURING METHOD Of THE SAME
EP3355981A4 (en) 2015-09-28 2019-05-22 Vaxxas Pty Limited MICROAILLY NETWORK HAVING IMPROVED SKIN PENETRATION PROPERTIES AND ASSOCIATED METHODS
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
CN107569238A (en) * 2016-07-04 2018-01-12 中山大学 A kind of adhesive type chimney type microneedle array and its manufacture method
WO2018176102A1 (en) 2017-03-31 2018-10-04 Vaxxas Pty Limited Device and method for coating surfaces
US11701506B2 (en) * 2017-05-10 2023-07-18 Chee Yen Lim Pyramidal microneedles with enhanced drug loading capacity and method for manufacturing
WO2018227246A1 (en) 2017-06-13 2018-12-20 Vaxxas Pty Limited Quality control of substrate coatings
CA3071680A1 (en) 2017-08-04 2019-02-07 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
US11785943B2 (en) * 2017-09-22 2023-10-17 Uchicago Argonne, Llc Tunable nanotextured materials
US11247896B2 (en) 2018-07-31 2022-02-15 Uchicago Argonne, Llc Localized functionalization of nanotextured surfaces
CN113874065A (en) 2019-05-16 2021-12-31 联邦高等教育系统匹兹堡大学 Microneedle arrays with undercut features for dermal and non-dermal drug delivery
US20220378183A1 (en) * 2019-12-25 2022-12-01 Sunstar Inc. Toothbrush
CN112569465B (en) * 2020-12-29 2022-07-19 华东理工大学 Preparation method of microneedle patch
JPWO2024005176A1 (en) * 2022-06-30 2024-01-04
CN115227976A (en) * 2022-07-20 2022-10-25 上海交通大学 A temperature control radio frequency microneedle system

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2747306B2 (en) * 1988-12-24 1998-05-06 富士通株式会社 Semiconductor device
KR100453132B1 (en) 1996-12-20 2004-10-15 앨자 코포레이션 Device and method for enhancing transdermal agent flux
JPH11286439A (en) 1998-04-01 1999-10-19 Senju Pharmaceut Co Ltd Biodegradable polymer-type drug release system
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
JP2005021678A (en) 2003-06-10 2005-01-27 Medorekkusu:Kk Pad base for percutaneous admistration and its manufacturing method
JP2005021677A (en) 2003-06-10 2005-01-27 Medorekkusu:Kk Pad base for percutaneous administration and injection needle
US20060127465A1 (en) * 2003-06-10 2006-06-15 Shinya Maenosono Pad base for transdermal administration and needle
JP2007509704A (en) 2003-10-31 2007-04-19 アルザ・コーポレーシヨン Systems and methods for transdermal vaccine delivery
US20050153873A1 (en) 2004-01-09 2005-07-14 Chan Keith T. Frequency assisted transdermal agent delivery method and system
JP4832082B2 (en) 2004-02-03 2011-12-07 久光製薬株式会社 Interface for transdermal drug delivery device
WO2006016647A1 (en) 2004-08-12 2006-02-16 Hisamitsu Pharmaceutical Co., Inc. Transdermal drug administration apparatus with microneedle
WO2006075716A1 (en) 2005-01-14 2006-07-20 Fujikura Ltd. Drug delivery instrument and method of producing the same
JPWO2006075689A1 (en) 2005-01-14 2008-06-12 久光製薬株式会社 Medicinal product carrying device and method for producing the same
JP2006341089A (en) * 2005-05-13 2006-12-21 Fujikura Ltd Medicinal product carrying device and method of manufacturing
JP5020080B2 (en) 2005-05-13 2012-09-05 久光製薬株式会社 Manufacturing method of medical equipment
WO2007012114A1 (en) 2005-07-25 2007-02-01 Nanotechnology Victoria Pty Ltd Microarray device
JP5000866B2 (en) 2005-08-01 2012-08-15 久光製薬株式会社 Non-toxic biopharmaceutical transport equipment
ATE532553T1 (en) 2006-02-10 2011-11-15 Hisamitsu Pharmaceutical Co TRANSDERMAL DRUG ADMINISTRATION DEVICE WITH MICRONEEDLES
JP4908893B2 (en) 2006-03-30 2012-04-04 久光製薬株式会社 Medicinal product carrying device, method for producing the same, and method for producing a mold for producing a medicinal product carrying device
US20090099502A1 (en) 2006-04-07 2009-04-16 Hisamitsu Pharmaceutical Co., Inc. Microneedle Device And Transdermal Administration Device Provided With Microneedles
JP5241517B2 (en) 2007-02-06 2013-07-17 久光製薬株式会社 Microneedle device for allergy diagnosis
JP4978245B2 (en) * 2007-03-08 2012-07-18 凸版印刷株式会社 Needle-shaped body, needle-shaped body manufacturing method, and drug transport device
WO2008139648A1 (en) 2007-05-15 2008-11-20 Hisamitsu Pharmaceutical Co., Inc. Method of coating microneedle
JP5194632B2 (en) 2007-08-15 2013-05-08 凸版印刷株式会社 Manufacturing method of needle-shaped body
JP5227558B2 (en) 2007-09-19 2013-07-03 凸版印刷株式会社 Acicular body
WO2009051147A1 (en) 2007-10-18 2009-04-23 Hisamitsu Pharmaceutical Co., Inc. Microneedle device

Also Published As

Publication number Publication date
US20120136312A1 (en) 2012-05-31
US8696638B2 (en) 2014-04-15
WO2011010605A1 (en) 2011-01-27
KR101686692B1 (en) 2016-12-14
EP2457592A4 (en) 2013-01-02
EP2457592A1 (en) 2012-05-30
EP2457592B1 (en) 2020-09-16
JPWO2011010605A1 (en) 2012-12-27
CN102470179A (en) 2012-05-23
KR20120037910A (en) 2012-04-20
ES2826882T3 (en) 2021-05-19
JP5620911B2 (en) 2014-11-05

Similar Documents

Publication Publication Date Title
IN2012DN00906A (en)
WO2011163377A3 (en) Polylactic acid gloves and methods of manufacturing same
BRPI0917193A2 (en) polymer composition, article of manufacture, and method of producing a polymer composition.
GB2491527B (en) Degradation promoter of biodegradable resin molded body, and use thereof
EP2559731A4 (en) POLYACETAL RESIN COMPOSITION, METHOD FOR PRODUCING THE COMPOSITION, AND MOLDED ARTICLE
WO2011011241A3 (en) Implantable medical device comprising copolymer of l-lactide with improved fracture toughness
MX2013003262A (en) New impact modifier and impact modified thermoplastic composition.
WO2011084521A3 (en) Therapeutic polymeric nanoparticles comprising epothilone and methods of making and using same
IN2014DN09470A (en)
MX343108B (en) Fabric care compositions comprising organosiloxane polymers.
WO2011148177A3 (en) Membrane enhanced polymer synthesis
PL2493946T3 (en) Aqueous formulations based on crystalline or semicrystalline polyurethane polymers
WO2009027186A3 (en) Hyperbranched polymers comprising guanidine units
WO2010134772A2 (en) Resin composition for a disposable resin molded product, and disposable resin molded product
MY167878A (en) Storage-stable polyurethane prepregs and molded parts produced therefrom made of polyurethane composition having liquid resin components
EP2489686A4 (en) POLYPROPYLENE RESIN, POLYPROPYLENE RESIN COMPOSITION AND INJECTION MOLDED FOAM ARTICLE
PL2601252T3 (en) Polymer nanocomposite comprising polylactic acid reinforced with the modified phyllosilicate
EP2551302A4 (en) RESIN COMPOSITION, SYNTHETIC RESIN SHEET, SYNTHETIC RESIN MOLDED ARTICLE, AND SYNTHETIC RESIN LAMINATE
MX351904B (en) Reforming agent combinations.
EP2599821A4 (en) Polylactic acid resin sheet and molded article
WO2011059819A3 (en) Polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer
IL214863A0 (en) Polymer fiber, its use and process for its manufacture
EP2169006A4 (en) Injection molded article of fiber-reinforced polylactic acid resin
WO2012124941A3 (en) Recombinant microorganism having ability to produce polyhydroxyalkanoate containing 2-hydroxybutyrate as monomer, and method for preparing polyhydroxyalkanoate containing 2-hydroxybutyrate as monomer using same
MX2012006834A (en) Controlled synthesis of polyglutamic acid.