KR101511134B1 - 종양-연관 항원을 발현하는 암에 대한 펩티드 백신 - Google Patents

종양-연관 항원을 발현하는 암에 대한 펩티드 백신 Download PDF

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KR101511134B1
KR101511134B1 KR1020097019583A KR20097019583A KR101511134B1 KR 101511134 B1 KR101511134 B1 KR 101511134B1 KR 1020097019583 A KR1020097019583 A KR 1020097019583A KR 20097019583 A KR20097019583 A KR 20097019583A KR 101511134 B1 KR101511134 B1 KR 101511134B1
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KR20090121349A (ko
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타쿠야 츠노다
류지 오사와
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온코세라피 사이언스 가부시키가이샤
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001122—Ephrin Receptors [Eph]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
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    • A—HUMAN NECESSITIES
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/422—Ephrin Receptors [Eph]
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4225—Growth factors
    • A61K40/4229—Transforming growth factor [TGF]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
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    • A61K40/4244—Enzymes
    • A61K40/4251—Kinases, e.g. Raf or Src
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4254—Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
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  • Immunology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Dispersion Chemistry (AREA)
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KR1020097019583A 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신 Expired - Fee Related KR101511134B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90294907P 2007-02-21 2007-02-21
US60/902,949 2007-02-21
PCT/JP2008/000290 WO2008102557A1 (en) 2007-02-21 2008-02-21 Peptide vaccines for cancers expressing tumor-associated antigens

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1020137004417A Division KR101511140B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020147026715A Division KR101540000B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신

Publications (2)

Publication Number Publication Date
KR20090121349A KR20090121349A (ko) 2009-11-25
KR101511134B1 true KR101511134B1 (ko) 2015-04-28

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ID=39709837

Family Applications (8)

Application Number Title Priority Date Filing Date
KR1020097019583A Expired - Fee Related KR101511134B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020157026286A Abandoned KR20150116463A (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020137004417A Active KR101511140B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020157002221A Expired - Fee Related KR101644877B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020167010159A Withdrawn KR20160045939A (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020147026715A Expired - Fee Related KR101540000B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020157013656A Expired - Fee Related KR101644871B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020147026728A Expired - Fee Related KR101543623B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신

Family Applications After (7)

Application Number Title Priority Date Filing Date
KR1020157026286A Abandoned KR20150116463A (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020137004417A Active KR101511140B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020157002221A Expired - Fee Related KR101644877B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020167010159A Withdrawn KR20160045939A (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020147026715A Expired - Fee Related KR101540000B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020157013656A Expired - Fee Related KR101644871B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신
KR1020147026728A Expired - Fee Related KR101543623B1 (ko) 2007-02-21 2008-02-21 종양-연관 항원을 발현하는 암에 대한 펩티드 백신

Country Status (27)

Country Link
EP (20) EP2465866A3 (enExample)
JP (6) JP5239103B2 (enExample)
KR (8) KR101511134B1 (enExample)
CN (4) CN101663315B (enExample)
AR (1) AR068302A1 (enExample)
AU (1) AU2008218463B2 (enExample)
BR (1) BRPI0808421B1 (enExample)
CA (3) CA2678755C (enExample)
CO (1) CO6190536A2 (enExample)
CY (2) CY1114590T1 (enExample)
DK (3) DK2476694T3 (enExample)
ES (6) ES2530777T3 (enExample)
HR (3) HRP20131044T1 (enExample)
IL (10) IL200478A (enExample)
MX (4) MX337417B (enExample)
MY (2) MY173379A (enExample)
NZ (4) NZ579768A (enExample)
PH (1) PH12014501642A1 (enExample)
PL (3) PL2465864T3 (enExample)
PT (2) PT2121731E (enExample)
RU (1) RU2464275C2 (enExample)
SG (3) SG10201909675QA (enExample)
SI (3) SI2465864T1 (enExample)
TW (5) TWI494319B (enExample)
UA (1) UA100372C2 (enExample)
WO (1) WO2008102557A1 (enExample)
ZA (1) ZA200905881B (enExample)

Families Citing this family (38)

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JP4614952B2 (ja) 2003-08-20 2011-01-19 オンコセラピー・サイエンス株式会社 腎細胞癌（ｒｃｃ）の潜在的な新規治療標的としての低酸素誘導タンパク質２（ｈｉｇ２）
CA2696591C (en) * 2007-08-20 2016-10-11 Oncotherapy Science, Inc. Cdh3 peptide and medicinal agent comprising the same
RU2011103199A (ru) 2008-06-30 2012-08-10 Онкотерапи Сайенс, Инк. (Jp) Антитела против cdh3, меченные радиоизотопной меткой, и их применение
TWI580431B (zh) * 2008-08-19 2017-05-01 腫瘤療法 科學股份有限公司 Ｈｉｇ２與ｕｒｌｃ１０抗原決定位胜肽以及含此胜肽之疫苗
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
CN104086625B (zh) * 2008-10-22 2016-08-31 肿瘤疗法科学股份有限公司 Rab6kifl/kif20a表位肽及包含它的疫苗
TWI500932B (zh) 2008-12-05 2015-09-21 Oncotherapy Science Inc Ｗｄｒｐｕｈ抗原決定位胜肽以及含此胜肽之疫苗
US8735361B2 (en) 2008-12-24 2014-05-27 Oncotherapy Science, Inc. C1ORF59 peptides and vaccines including the same
TW201102081A (en) * 2009-05-11 2011-01-16 Oncotherapy Science Inc TTK peptides and vaccines including the same
US8703808B2 (en) 2009-06-23 2014-04-22 Centre National De La Recherche Scientifique Use of derivatives of indoles for the treatment of cancer
JP5728718B2 (ja) 2009-12-28 2015-06-03 オンコセラピー・サイエンス株式会社 抗ｃｄｈ３抗体およびその使用
ES2575160T3 (es) 2010-03-15 2016-06-24 The Board Of Trustees Of The University Of Illinois Inhibidores de las interacciones que unen la subunidad alfa de la beta integrina-proteína G
TWI538685B (zh) * 2010-04-02 2016-06-21 腫瘤療法 科學股份有限公司 Ｅｃｔ２胜肽及含此胜肽之疫苗
MY166516A (en) * 2010-12-02 2018-07-05 Oncotherapy Science Inc Tomm34 peptides and vaccines including the same
HUE045359T2 (hu) * 2011-12-14 2019-12-30 Univ Texas Kollaterális gén inaktiváló biomarkerek és célsejtek a rákterápiában
WO2013133405A1 (ja) 2012-03-09 2013-09-12 オンコセラピー・サイエンス株式会社 ペプチドを含む医薬組成物
EP2872531A4 (en) 2012-07-10 2016-04-06 Oncotherapy Science Inc LY6K EPITOPE PEPTIDES FOR TH1 CELLS AND VACCINES CONTAINING SAME
EP2872530A4 (en) * 2012-07-10 2016-04-06 Oncotherapy Science Inc KIF20A EPITOPE PEPTIDES FOR TH1 CELLS AND VACCINES CONTAINING SAME
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