KR101366353B1 - 인슐린 측정 방법 - Google Patents

인슐린 측정 방법 Download PDF

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Publication number
KR101366353B1
KR101366353B1 KR1020117013678A KR20117013678A KR101366353B1 KR 101366353 B1 KR101366353 B1 KR 101366353B1 KR 1020117013678 A KR1020117013678 A KR 1020117013678A KR 20117013678 A KR20117013678 A KR 20117013678A KR 101366353 B1 KR101366353 B1 KR 101366353B1
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South Korea
Prior art keywords
insulin
antibody
measuring
reagent
monoclonal antibody
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Korean (ko)
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KR20110095349A (ko
Inventor
준이찌 곤도우
도모 시미즈
미쯔아끼 야마모또
야스시 나까무라
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세키스이 메디칼 가부시키가이샤
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541—Double or second antibody, i.e. precipitating antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/62—Insulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020117013678A 2009-07-21 2010-07-21 인슐린 측정 방법 Active KR101366353B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009170292 2009-07-21
JPJP-P-2009-170292 2009-07-21
PCT/JP2010/062261 WO2011010673A1 (ja) 2009-07-21 2010-07-21 インスリン測定方法

Publications (2)

Publication Number Publication Date
KR20110095349A KR20110095349A (ko) 2011-08-24
KR101366353B1 true KR101366353B1 (ko) 2014-02-21

Family

ID=43499145

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117013678A Active KR101366353B1 (ko) 2009-07-21 2010-07-21 인슐린 측정 방법

Country Status (11)

Country Link
US (1) US9476891B2 (enExample)
EP (1) EP2458378B1 (enExample)
JP (2) JP4782249B2 (enExample)
KR (1) KR101366353B1 (enExample)
CN (1) CN102246039A (enExample)
AU (1) AU2010274320B2 (enExample)
BR (1) BRPI1005176B1 (enExample)
CA (1) CA2739310C (enExample)
MX (1) MX2011003927A (enExample)
MY (1) MY151976A (enExample)
WO (1) WO2011010673A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013059805A1 (en) * 2011-10-21 2013-04-25 Decimadx, Llc Point-of care immunoassay for quantitative small analyte detection
EP3540438A1 (en) * 2012-08-17 2019-09-18 MorphoSys AG Complex-specific antibodies and antibody fragments and its use
JP6457933B2 (ja) * 2013-03-29 2019-01-23 積水メディカル株式会社 インスリン測定方法
JP6182027B2 (ja) * 2013-09-10 2017-08-16 デンカ生研株式会社 Ｂ型インフルエンザウイルスの測定方法
CN105866420B (zh) * 2015-01-22 2018-11-16 艾托金生物医药（苏州）有限公司 一种检测免疫原的方法和装置
CN106918708A (zh) * 2015-12-28 2017-07-04 北京九强生物技术股份有限公司 一种用于检测胰岛素的竞争法胶乳增强免疫透射比浊试剂盒
JP6862845B2 (ja) * 2016-01-22 2021-04-21 日立化成ダイアグノスティックス・システムズ株式会社 可溶性インターロイキン−２受容体の測定方法及び測定用試薬
US11435367B2 (en) 2016-07-29 2022-09-06 Diazyme Laboratories, Inc. Methods and kits for assaying a vitamin D moiety
US12222351B2 (en) 2018-10-09 2025-02-11 Sekisui Medical Co., Ltd. Immunoassay and measurement reagent for leucine-rich alpha2 glycoprotein
CN111690064A (zh) * 2020-06-24 2020-09-22 合肥天麦生物科技发展有限公司 一种胰岛素原前体蛋白的检测方法及其ppi单克隆抗体的制备方法
CN114195892B (zh) * 2020-09-18 2024-08-13 苏州鲲鹏生物技术有限公司 一种人胰岛素单链前体残留检测控制方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009552A1 (en) 1994-09-21 1996-03-28 Behringwerke Aktiengesellschaft Method for detecting antibodies

Family Cites Families (19)

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Publication number Priority date Publication date Assignee Title
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
JPH0619352B2 (ja) * 1985-06-10 1994-03-16 帝人株式会社 ヒト・プロテインｃの測定方法
DE3636724A1 (de) * 1986-10-29 1988-06-23 Joern Dr Med Kekow Enzymimmunoassay (elisa) zur insulinbestimmung im mikrotiterplattensystem
JPH0198968A (ja) 1987-10-12 1989-04-17 Tosoh Corp ヒス・インスリンの測定方法
JPH01148962A (ja) 1987-12-07 1989-06-12 Tosoh Corp インスリン免疫測定法
DE3806430A1 (de) * 1988-02-29 1989-09-07 Boehringer Mannheim Gmbh Verfahren zur bestimmung eines proteins nach dem prinzip des fluoreszenz-polarisations-immunoassays
US5583003A (en) * 1989-09-25 1996-12-10 Agen Limited Agglutination assay
JPH03118472A (ja) 1989-09-29 1991-05-21 Sekisui Chem Co Ltd インスリン定量方法及び定量試薬
WO1992005282A1 (en) * 1990-09-14 1992-04-02 Biosite Diagnostics, Inc. Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
JPH05297000A (ja) 1992-04-17 1993-11-12 S R L:Kk インスリン抗体の測定方法
JP3479100B2 (ja) * 1993-06-02 2003-12-15 帝国臓器製薬株式会社 免疫化学的簡易半定量方法および装置
US6103536A (en) * 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
AU2002313319B2 (en) * 2001-07-02 2007-05-10 Sekisui Medical Co., Ltd. Carrier particle latex for assay reagent and assay reagent
FI20022048A0 (fi) * 2002-11-18 2002-11-18 Valtion Teknillinen Ei-kompetetiivinen immunomääritys pienille analyyteille
ES2367032T3 (es) * 2004-12-28 2011-10-27 Sekisui Medical Co., Ltd. Anticuerpo monoclonal anti-fibrina soluble humana y procedimiento de ensayo inmunológico usando el anticuerpo.
JP4448149B2 (ja) 2007-02-19 2010-04-07 浜松ホトニクス株式会社 蛍光免疫測定方法
EP2234644B1 (en) * 2008-01-04 2013-07-31 Biodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
JP5115852B2 (ja) 2008-04-28 2013-01-09 国立大学法人電気通信大学 コグニティブ無線通信システム、通信方法、および通信機器
MX2011002337A (es) * 2008-09-05 2011-04-05 Sekisui Medical Co Ltd Anticuerpo monoclonal e inmunoanalisis que utiliza el mismo.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996009552A1 (en) 1994-09-21 1996-03-28 Behringwerke Aktiengesellschaft Method for detecting antibodies

Also Published As

Publication number Publication date
US20110195438A1 (en) 2011-08-11
MY151976A (en) 2014-07-31
MX2011003927A (es) 2011-07-20
KR20110095349A (ko) 2011-08-24
CN102246039A (zh) 2011-11-16
JP5661572B2 (ja) 2015-01-28
AU2010274320B2 (en) 2013-08-01
JP4782249B2 (ja) 2011-09-28
EP2458378B1 (en) 2017-12-06
CA2739310C (en) 2014-07-08
WO2011010673A1 (ja) 2011-01-27
JPWO2011010673A1 (ja) 2013-01-07
US9476891B2 (en) 2016-10-25
EP2458378A1 (en) 2012-05-30
JP2011237442A (ja) 2011-11-24
BRPI1005176A2 (pt) 2016-12-06
AU2010274320A1 (en) 2011-01-27
CA2739310A1 (en) 2011-01-27
EP2458378A4 (en) 2013-01-02
BRPI1005176B1 (pt) 2021-06-08

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