BRPI1005176A2 - ensaio de insulina, reagente de ensaio de insulina, anticorpo monoclonal, e, método de triar anticorpos monoclonais. - Google Patents
ensaio de insulina, reagente de ensaio de insulina, anticorpo monoclonal, e, método de triar anticorpos monoclonais.Info
- Publication number
- BRPI1005176A2 BRPI1005176A2 BRPI1005176A BRPI1005176A BRPI1005176A2 BR PI1005176 A2 BRPI1005176 A2 BR PI1005176A2 BR PI1005176 A BRPI1005176 A BR PI1005176A BR PI1005176 A BRPI1005176 A BR PI1005176A BR PI1005176 A2 BRPI1005176 A2 BR PI1005176A2
- Authority
- BR
- Brazil
- Prior art keywords
- insulin assay
- monoclonal antibody
- screening
- monoclonal antibodies
- insulin
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 4
- 102000004877 Insulin Human genes 0.000 title 2
- 108090001061 Insulin Proteins 0.000 title 2
- 238000003556 assay Methods 0.000 title 2
- 229940125396 insulin Drugs 0.000 title 2
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
- G01N33/541—Double or second antibody, i.e. precipitating antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/62—Insulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
- G01N2470/04—Sandwich assay format
- G01N2470/06—Second binding partner specifically binding complex of analyte with first binding partner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009-170292 | 2009-07-21 | ||
| JP2009170292 | 2009-07-21 | ||
| PCT/JP2010/062261 WO2011010673A1 (ja) | 2009-07-21 | 2010-07-21 | インスリン測定方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1005176A2 true BRPI1005176A2 (pt) | 2016-12-06 |
| BRPI1005176B1 BRPI1005176B1 (pt) | 2021-06-08 |
Family
ID=43499145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1005176-7A BRPI1005176B1 (pt) | 2009-07-21 | 2010-07-21 | ensaio de insulina e reagente de ensaio de insulina |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9476891B2 (pt) |
| EP (1) | EP2458378B1 (pt) |
| JP (2) | JP4782249B2 (pt) |
| KR (1) | KR101366353B1 (pt) |
| CN (1) | CN102246039A (pt) |
| AU (1) | AU2010274320B2 (pt) |
| BR (1) | BRPI1005176B1 (pt) |
| CA (1) | CA2739310C (pt) |
| MX (1) | MX2011003927A (pt) |
| MY (1) | MY151976A (pt) |
| WO (1) | WO2011010673A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2769219B1 (en) * | 2011-10-21 | 2017-08-30 | Decimadx LLC | Point-of care immunoassay for quantitative small analyte detection |
| JP6437913B2 (ja) * | 2012-08-17 | 2018-12-12 | モルフォシス・アーゲー | 複合体特異的抗体及び抗体断片並びにその使用 |
| EP2980586B1 (en) | 2013-03-29 | 2017-08-16 | Sekisui Medical Co., Ltd. | Insulin assay method |
| JP6182027B2 (ja) * | 2013-09-10 | 2017-08-16 | デンカ生研株式会社 | Ｂ型インフルエンザウイルスの測定方法 |
| CN105866420B (zh) * | 2015-01-22 | 2018-11-16 | 艾托金生物医药（苏州）有限公司 | 一种检测免疫原的方法和装置 |
| CN106918708A (zh) * | 2015-12-28 | 2017-07-04 | 北京九强生物技术股份有限公司 | 一种用于检测胰岛素的竞争法胶乳增强免疫透射比浊试剂盒 |
| JP6862845B2 (ja) * | 2016-01-22 | 2021-04-21 | 日立化成ダイアグノスティックス・システムズ株式会社 | 可溶性インターロイキン−２受容体の測定方法及び測定用試薬 |
| CN109863406B (zh) | 2016-07-29 | 2023-04-14 | Diazyme研究室有限公司 | 用于测定维生素d的方法和成分 |
| JP7421711B2 (ja) * | 2018-10-09 | 2024-01-25 | 積水メディカル株式会社 | ロイシンリッチα２グリコプロテインの免疫測定方法及び測定試薬 |
| CN111690064A (zh) * | 2020-06-24 | 2020-09-22 | 合肥天麦生物科技发展有限公司 | 一种胰岛素原前体蛋白的检测方法及其ppi单克隆抗体的制备方法 |
| CN114195892B (zh) * | 2020-09-18 | 2024-08-13 | 苏州鲲鹏生物技术有限公司 | 一种人胰岛素单链前体残留检测控制方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4514505A (en) * | 1982-05-21 | 1985-04-30 | The Trustees Of Columbia University In The City Of New York | Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays |
| JPH0619352B2 (ja) * | 1985-06-10 | 1994-03-16 | 帝人株式会社 | ヒト・プロテインｃの測定方法 |
| DE3636724A1 (de) * | 1986-10-29 | 1988-06-23 | Joern Dr Med Kekow | Enzymimmunoassay (elisa) zur insulinbestimmung im mikrotiterplattensystem |
| JPH0198968A (ja) * | 1987-10-12 | 1989-04-17 | Tosoh Corp | ヒス・インスリンの測定方法 |
| JPH01148962A (ja) | 1987-12-07 | 1989-06-12 | Tosoh Corp | インスリン免疫測定法 |
| DE3806430A1 (de) * | 1988-02-29 | 1989-09-07 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines proteins nach dem prinzip des fluoreszenz-polarisations-immunoassays |
| US5583003A (en) * | 1989-09-25 | 1996-12-10 | Agen Limited | Agglutination assay |
| JPH03118472A (ja) | 1989-09-29 | 1991-05-21 | Sekisui Chem Co Ltd | インスリン定量方法及び定量試薬 |
| CA2072758A1 (en) * | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| JPH05297000A (ja) * | 1992-04-17 | 1993-11-12 | S R L:Kk | インスリン抗体の測定方法 |
| JP3479100B2 (ja) * | 1993-06-02 | 2003-12-15 | 帝国臓器製薬株式会社 | 免疫化学的簡易半定量方法および装置 |
| US5561049A (en) * | 1994-09-21 | 1996-10-01 | Behringwerke Ag | Method for detecting antibodies |
| US6103536A (en) * | 1997-05-02 | 2000-08-15 | Silver Lake Research Corporation | Internally referenced competitive assays |
| KR100894947B1 (ko) * | 2001-07-02 | 2009-04-27 | 세키스이 메디칼 가부시키가이샤 | 측정 시약용 담체 입자 라텍스 및 측정 시약 |
| FI20022048A0 (fi) | 2002-11-18 | 2002-11-18 | Valtion Teknillinen | Ei-kompetetiivinen immunomääritys pienille analyyteille |
| EP1832654B1 (en) * | 2004-12-28 | 2011-07-27 | Sekisui Medical Co., Ltd. | Anti-human soluble fibrin monoclonal antibody and immunological assay method using the antibody |
| JP4448149B2 (ja) * | 2007-02-19 | 2010-04-07 | 浜松ホトニクス株式会社 | 蛍光免疫測定方法 |
| CN101951957A (zh) * | 2008-01-04 | 2011-01-19 | 百达尔公司 | 胰岛素释放作为组织的葡萄糖水平的函数的胰岛素制剂 |
| JP5115852B2 (ja) | 2008-04-28 | 2013-01-09 | 国立大学法人電気通信大学 | コグニティブ無線通信システム、通信方法、および通信機器 |
| EP2322562B1 (en) * | 2008-09-05 | 2016-03-30 | Sekisui Medical Co., Ltd. | Monoclonal antibody, and immunoassay using same |
-
2010
- 2010-07-21 AU AU2010274320A patent/AU2010274320B2/en not_active Ceased
- 2010-07-21 CA CA2739310A patent/CA2739310C/en active Active
- 2010-07-21 KR KR1020117013678A patent/KR101366353B1/ko active IP Right Grant
- 2010-07-21 BR BRPI1005176-7A patent/BRPI1005176B1/pt not_active IP Right Cessation
- 2010-07-21 JP JP2010546566A patent/JP4782249B2/ja not_active Expired - Fee Related
- 2010-07-21 CN CN2010800035212A patent/CN102246039A/zh active Pending
- 2010-07-21 EP EP10802293.0A patent/EP2458378B1/en not_active Not-in-force
- 2010-07-21 WO PCT/JP2010/062261 patent/WO2011010673A1/ja active Application Filing
- 2010-07-21 MX MX2011003927A patent/MX2011003927A/es active IP Right Grant
- 2010-07-21 US US13/122,930 patent/US9476891B2/en active Active
- 2010-07-21 MY MYPI2011001622 patent/MY151976A/en unknown
-
2011
- 2011-07-06 JP JP2011149985A patent/JP5661572B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4782249B2 (ja) | 2011-09-28 |
| BRPI1005176B1 (pt) | 2021-06-08 |
| MX2011003927A (es) | 2011-07-20 |
| KR20110095349A (ko) | 2011-08-24 |
| US9476891B2 (en) | 2016-10-25 |
| CA2739310C (en) | 2014-07-08 |
| US20110195438A1 (en) | 2011-08-11 |
| JP2011237442A (ja) | 2011-11-24 |
| AU2010274320A1 (en) | 2011-01-27 |
| EP2458378A1 (en) | 2012-05-30 |
| WO2011010673A1 (ja) | 2011-01-27 |
| JP5661572B2 (ja) | 2015-01-28 |
| CA2739310A1 (en) | 2011-01-27 |
| EP2458378A4 (en) | 2013-01-02 |
| AU2010274320B2 (en) | 2013-08-01 |
| MY151976A (en) | 2014-07-31 |
| EP2458378B1 (en) | 2017-12-06 |
| CN102246039A (zh) | 2011-11-16 |
| KR101366353B1 (ko) | 2014-02-21 |
| JPWO2011010673A1 (ja) | 2013-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: SEKISUI MEDICAL CO., LTD. (JP) |
|
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/07/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 14A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2784 DE 14-05-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |