BRPI0906060A2 - anticorpos isolados, métodos de preparo de um anticorpo anti-clostridium difficile, composição e método para a detecção da presença de um esporo de clostridium difficile em uma amostra - Google Patents

anticorpos isolados, métodos de preparo de um anticorpo anti-clostridium difficile, composição e método para a detecção da presença de um esporo de clostridium difficile em uma amostra

Info

Publication number
BRPI0906060A2
BRPI0906060A2 BRPI0906060A BRPI0906060A BRPI0906060A2 BR PI0906060 A2 BRPI0906060 A2 BR PI0906060A2 BR PI0906060 A BRPI0906060 A BR PI0906060A BR PI0906060 A BRPI0906060 A BR PI0906060A BR PI0906060 A2 BRPI0906060 A2 BR PI0906060A2
Authority
BR
Brazil
Prior art keywords
clostridium difficile
preparing
sample
detecting
composition
Prior art date
Application number
BRPI0906060A
Other languages
English (en)
Inventor
Ai-Ping Wei
Raj Rajagopal
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of BRPI0906060A2 publication Critical patent/BRPI0906060A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1282—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/067—Pancreatitis or colitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0906060A 2008-02-28 2009-02-25 anticorpos isolados, métodos de preparo de um anticorpo anti-clostridium difficile, composição e método para a detecção da presença de um esporo de clostridium difficile em uma amostra BRPI0906060A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3227008P 2008-02-28 2008-02-28
PCT/US2009/035050 WO2009108652A1 (en) 2008-02-28 2009-02-25 Antibodies to clostridium difficile spores and uses thereof

Publications (1)

Publication Number Publication Date
BRPI0906060A2 true BRPI0906060A2 (pt) 2015-12-01

Family

ID=41016450

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906060A BRPI0906060A2 (pt) 2008-02-28 2009-02-25 anticorpos isolados, métodos de preparo de um anticorpo anti-clostridium difficile, composição e método para a detecção da presença de um esporo de clostridium difficile em uma amostra

Country Status (9)

Country Link
US (2) US8697374B2 (pt)
EP (1) EP2271366A4 (pt)
JP (1) JP2011512817A (pt)
KR (1) KR20100126760A (pt)
CN (1) CN101980723A (pt)
AU (1) AU2009219358A1 (pt)
BR (1) BRPI0906060A2 (pt)
CA (1) CA2714720A1 (pt)
WO (1) WO2009108652A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102388064A (zh) * 2009-03-27 2012-03-21 高裘企业公司 用于筛选与使用拮抗孢子-表面交互作用的化合物的组合物与方法
CN102533867A (zh) * 2010-12-10 2012-07-04 西北民族大学 一种艰难梭菌a毒素的类毒素的制备方法
US20120276060A1 (en) 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for treating infection in patients with clostridium difficile disease
US10295535B2 (en) * 2011-04-29 2019-05-21 Techlab, Inc. Clostridium difficile dehydrogenase and toxin as a biomarker for monitoring infection in patients with clostridium difficile disease and differentiating carrier state from active disease
EP2755681B1 (en) * 2011-09-15 2018-06-27 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center IMMUNOTHERAPY AND DIAGNOSIS OF MUCORMYCOSIS USING CotH
SG11201400193SA (en) * 2011-09-16 2014-05-29 Ucb Pharma Sa Neutralising antibodies to the major exotoxins tcda and tcdb of clostridium difficile
CA2856085C (en) 2011-11-18 2020-06-30 National Research Council Of Canada Clostridium difficile lipoteichoic acid and uses thereof
CN102590515B (zh) * 2012-01-13 2014-07-30 张春华 艰难梭菌外毒素a检测试剂盒及组成该试剂盒的单克隆抗体
CN108101983A (zh) 2012-03-02 2018-06-01 瑞泽恩制药公司 艰难梭状芽孢杆菌毒素的人源抗体
US9133527B2 (en) * 2012-05-11 2015-09-15 Techlab, Inc. Cell wall protein CwpV (CD0514) as a diagnostic marker for Clostridium difficile ribotype 027
US9079935B2 (en) 2012-08-13 2015-07-14 The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas Reducing risk of contracting Clostridium-difficile associated disease
WO2014045226A1 (en) * 2012-09-19 2014-03-27 Novartis Ag Clostridium difficile polypeptides as vaccine
AU2013352034B2 (en) * 2012-11-28 2018-08-02 Emergent Biosolutions Canada Inc. Antibodies against Clostridium difficile
EP2986316B1 (en) * 2013-04-19 2023-01-25 Immuron Limited Methods and compositions for the treatment and/or prophylaxis of clostridium difficile associated disease
EP3126840B1 (en) * 2014-04-01 2020-05-06 Institut Pasteur Predictive value of clostridium difficile-specific immune response for recurrence and disease outcome
CN106662529B (zh) 2014-06-09 2019-08-30 3M创新有限公司 检测目标分析物的测定装置和方法
US20180000793A1 (en) 2015-02-06 2018-01-04 Ernesto Abel-Santos Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis
US20190059860A1 (en) * 2015-09-21 2019-02-28 4C Diagnostics Ltd. Stool specimen collecting, sampling and diagnosing means and methods thereof
JP2022535131A (ja) * 2019-06-05 2022-08-04 リブ・プロセス・インコーポレイテッド クロストリジウム・ディフィシル菌に対するアプタマー
CN111948388B (zh) * 2020-08-18 2022-03-22 山东农业大学 一种检测腐败梭菌的胶体金试纸条及其制备方法和应用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4533630A (en) 1982-09-13 1985-08-06 Wilkins Tracy D Toxins and antibodies of C. difficile
US4530833A (en) 1982-09-13 1985-07-23 Wilkins Tracy D Toxins and antibodies of C. difficile
US4879218A (en) 1982-09-13 1989-11-07 Virginia Tech Intellectual Properties, Inc. Antibody for C.difficile
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8426464D0 (en) 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
US4863852A (en) 1985-07-03 1989-09-05 Virginia Tech Intellectual Properties, Inc. Method of detecting, isolating and purifying clostridium difficile toxin A and its receptors
US4956302A (en) 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
AU4308689A (en) 1988-09-02 1990-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
US5231003A (en) 1990-05-11 1993-07-27 Cambridge Bioscience Corporation Monoclonal antibodies specific for toxin b of clostridium difficile
AU665190B2 (en) 1990-07-10 1995-12-21 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DK0564531T3 (da) 1990-12-03 1998-09-28 Genentech Inc Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber
ATE363532T1 (de) 1991-03-01 2007-06-15 Dyax Corp Verfahren zur herstellung bindender miniproteine
ES2315612T3 (es) 1991-04-10 2009-04-01 The Scripps Research Institute Genotecas de receptores heterodimericos usando fagemidos.
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US5610023A (en) 1995-03-31 1997-03-11 Lee Laboratories, Inc. Method of purification of clostridium difficile toxin A and production of mono-specific antibodies
US5753517A (en) 1996-03-29 1998-05-19 University Of British Columbia Quantitative immunochromatographic assays
US7179611B2 (en) 1997-02-10 2007-02-20 Bd Lee Laboratories Mono-specific polyclonal antibodies and methods for detecting Clostridium difficile Toxin A
US5965375A (en) 1997-04-04 1999-10-12 Biosite Diagnostics Diagnostic tests and kits for Clostridium difficile
AU8395498A (en) * 1997-07-11 1999-02-08 Regents of The University of Arizona, The Hen egg yolk antibodies to (clostridium difficile) antigens and use in therapy for pseudomembranous colitis
US5876960A (en) 1997-08-11 1999-03-02 The United States Of America As Represented By The Secretary Of The Army Bacterial spore detection and quantification methods
US6733760B1 (en) 1999-04-09 2004-05-11 Techlab, Inc. Recombinant toxin A/toxin B vaccine against Clostridium difficile
US7074454B1 (en) 1999-11-01 2006-07-11 Mucovax Holding B.V. Production of mammary secretion antibodies in farm animals
PT1226176E (pt) 1999-11-01 2006-06-30 Mucovax Holding B V Producao de anticorpos de secrecao mamaria nos animais domesticos
US6974573B2 (en) 1999-11-01 2005-12-13 Mucovax Holdings, B.V. Antibody production in farm animals
US6509196B1 (en) 2000-01-04 2003-01-21 Response Biomedical Corp. Compensation for non-specific signals in quantitative immunoassays
GB0007263D0 (en) 2000-03-24 2000-05-17 Imperial College Peptides
US6498041B1 (en) 2000-08-18 2002-12-24 Echo Technologies, Inc. Optical sensors for rapid, sensitive detection and quantitation of bacterial spores
US6815178B1 (en) 2001-11-19 2004-11-09 Antony R. Shoaf Endospore detection method
EP1448761B1 (en) 2001-11-30 2007-08-22 California Institute Of Technology An improvement in a method bacterial endospore quantification using lanthanide dipicolinate luminescence
US7428045B2 (en) 2002-01-10 2008-09-23 Chemimage Corporation Raman spectral analysis of pathogens
JP2005516213A (ja) 2002-02-01 2005-06-02 カリフォルニア　インスティチュート　オブ　テクノロジー 細菌胞子の分析方法および装置
US20030175318A1 (en) 2002-03-06 2003-09-18 Schilling Amanda S. Application of germination solution improved efficacy of biological decontamination
US20040033546A1 (en) * 2002-04-10 2004-02-19 The Trustees Of Columbia University In The City Of New York Novel microarrays and methods of use thereof
US7608419B2 (en) 2003-11-13 2009-10-27 California Institute Of Technology Method and apparatus for detecting and quantifying bacterial spores on a surface
WO2004069848A2 (en) 2003-01-28 2004-08-19 Diversa Corporation Amidases, nucleic acids encoding them and methods for making and using them
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US20060275920A1 (en) 2005-06-01 2006-12-07 Petrilla John F Apparatus and method for discriminating among lateral flow assay test indicators

Also Published As

Publication number Publication date
EP2271366A1 (en) 2011-01-12
JP2011512817A (ja) 2011-04-28
WO2009108652A1 (en) 2009-09-03
KR20100126760A (ko) 2010-12-02
EP2271366A4 (en) 2012-06-20
US20110183360A1 (en) 2011-07-28
US20140335543A1 (en) 2014-11-13
CA2714720A1 (en) 2009-09-03
AU2009219358A1 (en) 2009-09-03
CN101980723A (zh) 2011-02-23
US8697374B2 (en) 2014-04-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2372 DE 21-06-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.