KR101363308B1 - 비만을 치료하기 위한 벤조―융합된 헤테로사이클 설파미드유도체의 용도 - Google Patents

비만을 치료하기 위한 벤조―융합된 헤테로사이클 설파미드유도체의 용도 Download PDF

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Publication number
KR101363308B1
KR101363308B1 KR1020087017531A KR20087017531A KR101363308B1 KR 101363308 B1 KR101363308 B1 KR 101363308B1 KR 1020087017531 A KR1020087017531 A KR 1020087017531A KR 20087017531 A KR20087017531 A KR 20087017531A KR 101363308 B1 KR101363308 B1 KR 101363308B1
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benzo
dihydro
compound
acid
dioxyyl
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KR20080089409A (ko
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버지니아 엘. 스미스-스윈토스키
알렌 비. 레이츠
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얀센 파마슈티카 엔.브이.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020087017531A 2005-12-19 2006-12-19 비만을 치료하기 위한 벤조―융합된 헤테로사이클 설파미드유도체의 용도 Expired - Fee Related KR101363308B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US75149905P 2005-12-19 2005-12-19
US60/751,499 2005-12-19
US11/611,938 US8492431B2 (en) 2005-12-19 2006-12-18 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US11/611,938 2006-12-18
PCT/US2006/048681 WO2007075833A2 (en) 2005-12-19 2006-12-19 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity

Publications (2)

Publication Number Publication Date
KR20080089409A KR20080089409A (ko) 2008-10-06
KR101363308B1 true KR101363308B1 (ko) 2014-02-18

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Family Applications (1)

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KR1020087017531A Expired - Fee Related KR101363308B1 (ko) 2005-12-19 2006-12-19 비만을 치료하기 위한 벤조―융합된 헤테로사이클 설파미드유도체의 용도

Country Status (30)

Country Link
US (1) US8492431B2 (https=)
EP (1) EP1968574B9 (https=)
JP (1) JP5190378B2 (https=)
KR (1) KR101363308B1 (https=)
CN (1) CN101365442B (https=)
AR (1) AR058389A1 (https=)
AT (1) ATE519484T1 (https=)
AU (1) AU2006331637B2 (https=)
BR (1) BRPI0620019A2 (https=)
CA (1) CA2634093C (https=)
CR (1) CR10164A (https=)
CY (1) CY1112357T1 (https=)
DK (1) DK1968574T3 (https=)
EA (1) EA016560B1 (https=)
ES (1) ES2369761T3 (https=)
HR (1) HRP20110726T2 (https=)
IL (1) IL192107A (https=)
ME (1) ME01344B (https=)
MY (1) MY145823A (https=)
NO (1) NO20083006L (https=)
NZ (1) NZ568960A (https=)
PE (1) PE20070813A1 (https=)
PL (1) PL1968574T3 (https=)
PT (1) PT1968574E (https=)
RS (1) RS52044B (https=)
SI (1) SI1968574T1 (https=)
SV (1) SV2008002952A (https=)
UY (1) UY30033A1 (https=)
WO (1) WO2007075833A2 (https=)
ZA (1) ZA200806279B (https=)

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US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8492431B2 (en) 2005-12-19 2013-07-23 Janssen Pharmaceutica, N.V. Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US20070155827A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
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US20090247616A1 (en) * 2008-03-26 2009-10-01 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety
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EP2271638B1 (en) * 2008-04-29 2011-08-31 NSAB, Filial af NeuroSearch Sweden AB, Sverige Modulators of dopamine neurotransmission
JP2011519839A (ja) * 2008-04-29 2011-07-14 エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ ドーパミン神経伝達のモジュレーター
EA018567B1 (ru) 2008-06-23 2013-08-30 Янссен Фармацевтика Нв Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида
US8815939B2 (en) * 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
JP2014528953A (ja) 2011-09-29 2014-10-30 ヤンセン ファーマシューティカ エヌ．ベー． スルファミド誘導体の調製プロセス
KR20140082762A (ko) 2011-09-29 2014-07-02 얀센 파마슈티카 엔.브이. 설파미드 유도체의 개선된 제조 방법

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