KR101282320B1 - Il-18 결합 단백질 - Google Patents
Il-18 결합 단백질 Download PDFInfo
- Publication number
- KR101282320B1 KR101282320B1 KR1020127001647A KR20127001647A KR101282320B1 KR 101282320 B1 KR101282320 B1 KR 101282320B1 KR 1020127001647 A KR1020127001647 A KR 1020127001647A KR 20127001647 A KR20127001647 A KR 20127001647A KR 101282320 B1 KR101282320 B1 KR 101282320B1
- Authority
- KR
- South Korea
- Prior art keywords
- antibody
- disease
- human
- seq
- binding portion
- Prior art date
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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| US10/706,689 US20050100965A1 (en) | 2003-11-12 | 2003-11-12 | IL-18 binding proteins |
| PCT/US2004/037971 WO2005047307A2 (en) | 2003-11-12 | 2004-11-12 | Il-18 binding proteins |
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| KR1020067009221A Division KR20060123148A (ko) | 2003-11-12 | 2004-11-12 | Il-18 결합 단백질 |
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| KR1020127031335A Division KR20130006525A (ko) | 2003-11-12 | 2004-11-12 | Il-18 결합 단백질 |
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| KR20120035192A KR20120035192A (ko) | 2012-04-13 |
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| KR1020067009221A Ceased KR20060123148A (ko) | 2003-11-12 | 2004-11-12 | Il-18 결합 단백질 |
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| KR1020127031335A Ceased KR20130006525A (ko) | 2003-11-12 | 2004-11-12 | Il-18 결합 단백질 |
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