PL1685152T3 - Białka wiążące IL-18 - Google Patents
Białka wiążące IL-18Info
- Publication number
- PL1685152T3 PL1685152T3 PL04817825T PL04817825T PL1685152T3 PL 1685152 T3 PL1685152 T3 PL 1685152T3 PL 04817825 T PL04817825 T PL 04817825T PL 04817825 T PL04817825 T PL 04817825T PL 1685152 T3 PL1685152 T3 PL 1685152T3
- Authority
- PL
- Poland
- Prior art keywords
- hil
- antibodies
- activity
- antibody
- binding proteins
- Prior art date
Links
- 102000044166 interleukin-18 binding protein Human genes 0.000 title abstract 2
- 108010070145 interleukin-18 binding protein Proteins 0.000 title abstract 2
- 101000960954 Homo sapiens Interleukin-18 Proteins 0.000 abstract 7
- 102000043959 human IL18 Human genes 0.000 abstract 7
- 230000000694 effects Effects 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001627 detrimental effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/706,689 US20050100965A1 (en) | 2003-11-12 | 2003-11-12 | IL-18 binding proteins |
| PCT/US2004/037971 WO2005047307A2 (en) | 2003-11-12 | 2004-11-12 | Il-18 binding proteins |
| EP04817825A EP1685152B1 (en) | 2003-11-12 | 2004-11-12 | Il-18 binding proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1685152T3 true PL1685152T3 (pl) | 2012-09-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04817825T PL1685152T3 (pl) | 2003-11-12 | 2004-11-12 | Białka wiążące IL-18 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20050100965A1 (pl) |
| EP (5) | EP2460829A3 (pl) |
| JP (4) | JP5054977B2 (pl) |
| KR (4) | KR20130006525A (pl) |
| CN (4) | CN102659944A (pl) |
| AT (1) | ATE555130T1 (pl) |
| AU (1) | AU2004290073B2 (pl) |
| BR (1) | BRPI0416255A (pl) |
| CA (2) | CA2805859A1 (pl) |
| CY (1) | CY1112893T1 (pl) |
| DK (1) | DK1685152T3 (pl) |
| ES (1) | ES2385484T3 (pl) |
| IL (2) | IL175422A0 (pl) |
| NZ (2) | NZ593068A (pl) |
| PL (1) | PL1685152T3 (pl) |
| PT (1) | PT1685152E (pl) |
| SI (1) | SI1685152T1 (pl) |
| WO (1) | WO2005047307A2 (pl) |
| ZA (1) | ZA200603733B (pl) |
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2003
- 2003-11-12 US US10/706,689 patent/US20050100965A1/en not_active Abandoned
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2004
- 2004-11-12 KR KR1020127031335A patent/KR20130006525A/ko not_active Ceased
- 2004-11-12 JP JP2006539948A patent/JP5054977B2/ja not_active Expired - Fee Related
- 2004-11-12 KR KR1020067009221A patent/KR20060123148A/ko not_active Ceased
- 2004-11-12 PL PL04817825T patent/PL1685152T3/pl unknown
- 2004-11-12 EP EP11173615A patent/EP2460829A3/en not_active Withdrawn
- 2004-11-12 ES ES04817825T patent/ES2385484T3/es not_active Expired - Lifetime
- 2004-11-12 CA CA2805859A patent/CA2805859A1/en not_active Abandoned
- 2004-11-12 WO PCT/US2004/037971 patent/WO2005047307A2/en not_active Ceased
- 2004-11-12 NZ NZ593068A patent/NZ593068A/xx not_active IP Right Cessation
- 2004-11-12 PT PT04817825T patent/PT1685152E/pt unknown
- 2004-11-12 AT AT04817825T patent/ATE555130T1/de active
- 2004-11-12 EP EP11173595A patent/EP2385070A1/en not_active Withdrawn
- 2004-11-12 CN CN2012101293119A patent/CN102659944A/zh active Pending
- 2004-11-12 EP EP04817825A patent/EP1685152B1/en not_active Expired - Lifetime
- 2004-11-12 KR KR1020127001647A patent/KR101282320B1/ko not_active Expired - Fee Related
- 2004-11-12 CN CN2004800399482A patent/CN1902229B/zh not_active Expired - Fee Related
- 2004-11-12 DK DK04817825.5T patent/DK1685152T3/da active
- 2004-11-12 CA CA002543920A patent/CA2543920A1/en not_active Abandoned
- 2004-11-12 KR KR1020127028781A patent/KR20120136416A/ko not_active Ceased
- 2004-11-12 EP EP11173631A patent/EP2460830A3/en not_active Withdrawn
- 2004-11-12 BR BRPI0416255-2A patent/BRPI0416255A/pt not_active IP Right Cessation
- 2004-11-12 EP EP11173650A patent/EP2395020A3/en not_active Withdrawn
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- 2004-11-12 AU AU2004290073A patent/AU2004290073B2/en not_active Ceased
- 2004-11-12 CN CN201010274020XA patent/CN101979412A/zh active Pending
- 2004-11-12 SI SI200431865T patent/SI1685152T1/sl unknown
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2006
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