MY177024A - Il-12/p40 binding proteins - Google Patents

Il-12/p40 binding proteins

Info

Publication number
MY177024A
MY177024A MYPI2010004295A MYPI2010004295A MY177024A MY 177024 A MY177024 A MY 177024A MY PI2010004295 A MYPI2010004295 A MY PI2010004295A MY PI2010004295 A MYPI2010004295 A MY PI2010004295A MY 177024 A MY177024 A MY 177024A
Authority
MY
Malaysia
Prior art keywords
hil
antibodies
activity
antibody
binding proteins
Prior art date
Application number
MYPI2010004295A
Inventor
Roguska Michael
E Lacy Susan
Fung Emma
P Belk Jonathan
W Dixon Richard
R Hinton Paul
Kumar Shankar
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Priority to MYPI2010004295A priority Critical patent/MY177024A/en
Publication of MY177024A publication Critical patent/MY177024A/en

Links

Landscapes

  • Peptides Or Proteins (AREA)

Abstract

The present invention encompasses IL-12p40 binding proteins, particularly antibodies that bind human interleukin-12 (hIL-12) and/or human IL-23 (hIL-23). Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-12 and/or hIL-23 and neutralize h IL-12 and/or hIL-23 activity in vitro and in viva. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and/or hIL-23 and for inhibiting hIL-12 and/or hIL-23 activity, e.g., in a human subject suffering from a disorder in which hIL-1 2 and/or hIL-23 activity is detrimental.
MYPI2010004295A 2010-09-14 2010-09-14 Il-12/p40 binding proteins MY177024A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MYPI2010004295A MY177024A (en) 2010-09-14 2010-09-14 Il-12/p40 binding proteins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI2010004295A MY177024A (en) 2010-09-14 2010-09-14 Il-12/p40 binding proteins

Publications (1)

Publication Number Publication Date
MY177024A true MY177024A (en) 2020-09-02

Family

ID=79169806

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI2010004295A MY177024A (en) 2010-09-14 2010-09-14 Il-12/p40 binding proteins

Country Status (1)

Country Link
MY (1) MY177024A (en)

Similar Documents

Publication Publication Date Title
TW200745160A (en) IL-12/P40 binding proteins
MY161894A (en) Interleukin-13 binding proteins
MX2011007987A (en) Il-1 binding proteins.
MX2010014573A (en) Prostaglandin e2 binding proteins and uses thereof.
IL206979A0 (en) Il-18 binding proteins
IN2012DN02634A (en)
MX2015008299A (en) Prolactin receptor binding proteins and uses thereof.
MX2009006740A (en) Human antibodies that bind human il-12 and methods for producing.
MY147468A (en) High affinity antibodies to human il-6 receptor
WO2008079361A3 (en) Cxcl13 binding proteins
WO2012088094A3 (en) Il-1 binding proteins
IL164011A0 (en) Antagonistic anti-hfas ligand human antibodies andfragments thereof
MY177024A (en) Il-12/p40 binding proteins
MY172707A (en) Il-12/p40 binding proteins
MY150711A (en) Il-12/p40 binding proteins
SG163559A1 (en) Il-12/p40 binding proteins