KR101256693B1 - 스위트피 추출물 함유 화장료 - Google Patents
스위트피 추출물 함유 화장료 Download PDFInfo
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- KR101256693B1 KR101256693B1 KR1020077025046A KR20077025046A KR101256693B1 KR 101256693 B1 KR101256693 B1 KR 101256693B1 KR 1020077025046 A KR1020077025046 A KR 1020077025046A KR 20077025046 A KR20077025046 A KR 20077025046A KR 101256693 B1 KR101256693 B1 KR 101256693B1
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- oil
- sweet pea
- acid
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPJP-P-2005-00106563 | 2005-04-01 | ||
| JP2005106563A JP4160964B2 (ja) | 2005-04-01 | 2005-04-01 | スイートピー抽出物含有化粧料 |
| PCT/JP2006/304966 WO2006112224A1 (ja) | 2005-04-01 | 2006-03-14 | スイートピー抽出物含有化粧料 |
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| KR20070116943A KR20070116943A (ko) | 2007-12-11 |
| KR101256693B1 true KR101256693B1 (ko) | 2013-04-19 |
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| KR1020077025046A Active KR101256693B1 (ko) | 2005-04-01 | 2006-03-14 | 스위트피 추출물 함유 화장료 |
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| US (1) | US7820211B2 (enExample) |
| JP (1) | JP4160964B2 (enExample) |
| KR (1) | KR101256693B1 (enExample) |
| CN (1) | CN101146513B (enExample) |
| WO (1) | WO2006112224A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190022114A (ko) | 2017-08-25 | 2019-03-06 | 대한민국(농촌진흥청장) | 연리초속 식물 추출물을 포함하는 항염증 활성을 갖는 조성물 |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5209355B2 (ja) * | 2007-03-29 | 2013-06-12 | 株式会社ファンケル | スイートピー抽出物 |
| TW200846017A (en) * | 2007-04-03 | 2008-12-01 | Fancl Corp | Apoptosis inhibitory agent |
| JP2008285637A (ja) * | 2007-05-21 | 2008-11-27 | Fancl Corp | 抗酸化剤 |
| CN103690411A (zh) * | 2013-12-04 | 2014-04-02 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的化妆水及其制备方法 |
| CN103690413A (zh) * | 2013-12-04 | 2014-04-02 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的身体乳及其制备方法 |
| CN103690456A (zh) * | 2013-12-04 | 2014-04-02 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的睡眠面膜及其制备方法 |
| CN103690412A (zh) * | 2013-12-04 | 2014-04-02 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的美容液及其制备方法 |
| CN103655444A (zh) * | 2013-12-04 | 2014-03-26 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的更年期女性专用眼霜 |
| CN103690418A (zh) * | 2013-12-06 | 2014-04-02 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的日霜及其制备方法 |
| CN103705411A (zh) * | 2013-12-06 | 2014-04-09 | 青岛海芬海洋生物科技有限公司 | 一种含有香豌豆提取液的面部乳液及其制备方法 |
| CN105434300B (zh) * | 2015-03-17 | 2018-10-12 | 欧诗漫生物股份有限公司 | 一种含珍珠粉的美白霜 |
| JP2022124930A (ja) * | 2021-02-16 | 2022-08-26 | 株式会社ファンケル | 皮膚外用剤、シワ改善剤、およびコラーゲン産生促進剤 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999048456A1 (en) | 1998-03-24 | 1999-09-30 | Unilever Plc | Moistened cosmetic eye treatment pads |
| JPH11315007A (ja) | 1998-05-01 | 1999-11-16 | Yamakawa Boeki Kk | コラーゲン産生促進剤および皮膚外用剤 |
| KR100271392B1 (ko) * | 1991-09-13 | 2000-11-15 | 카스파르 스튀름, 아를레테 슐레퍼 | 피부보호와 미용을 위한 단백질성분 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU83173A1 (fr) | 1981-02-27 | 1981-06-05 | Oreal | Nouvelles compositions cosmetiques pour le traitement des cheveux et de la peau contenant une poudre resultant de la pulverisation d'au moins une plante et un agent de cohesion |
| AU3270200A (en) | 1999-03-31 | 2000-10-23 | Pentapharm Ag | Composition for cosmetic and dermatological skin care |
| JP2001039852A (ja) | 1999-07-29 | 2001-02-13 | Nonogawa Shoji Kk | 皮膚外用剤 |
| JP4169899B2 (ja) | 2000-02-25 | 2008-10-22 | 花王株式会社 | 頭髪化粧料 |
| US6861077B1 (en) * | 2000-03-17 | 2005-03-01 | L'oreal S.A. | Use of plant extracts in a cosmetic composition to protect keratinous fibers |
| JP2002128653A (ja) * | 2000-10-26 | 2002-05-09 | Kuorika Produce:Kk | 皮膚の老化防止用化粧料 |
| FR2834718B1 (fr) | 2002-01-15 | 2004-12-24 | Cognis France Sa | Substances actives cosmetiques et/ou pharmaceutiques |
| JP2004018793A (ja) | 2002-06-20 | 2004-01-22 | Toray Ind Inc | ポリエステル系樹脂組成物 |
| JP2004035440A (ja) | 2002-07-02 | 2004-02-05 | Ichimaru Pharcos Co Ltd | くすみ抑制剤及び肌質改善用皮膚外用剤 |
| JP3953387B2 (ja) | 2002-07-15 | 2007-08-08 | オリザ油化株式会社 | エラスターゼ阻害剤 |
| JP2004083432A (ja) | 2002-08-23 | 2004-03-18 | Rohto Pharmaceut Co Ltd | エラスターゼ阻害剤 |
| KR100507293B1 (ko) * | 2002-12-16 | 2005-08-09 | 주식회사 태평양 | 열충격 단백질 생성 촉진 성분 및 이를 함유하는 피부미백용 외용제 조성물 |
| JP2004244382A (ja) | 2003-02-14 | 2004-09-02 | Ichimaru Pharcos Co Ltd | 化粧料組成物又は飲食品 |
-
2005
- 2005-04-01 JP JP2005106563A patent/JP4160964B2/ja not_active Expired - Fee Related
-
2006
- 2006-03-14 WO PCT/JP2006/304966 patent/WO2006112224A1/ja not_active Ceased
- 2006-03-14 KR KR1020077025046A patent/KR101256693B1/ko active Active
- 2006-03-14 CN CN2006800090209A patent/CN101146513B/zh active Active
- 2006-03-14 US US11/910,237 patent/US7820211B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100271392B1 (ko) * | 1991-09-13 | 2000-11-15 | 카스파르 스튀름, 아를레테 슐레퍼 | 피부보호와 미용을 위한 단백질성분 |
| WO1999048456A1 (en) | 1998-03-24 | 1999-09-30 | Unilever Plc | Moistened cosmetic eye treatment pads |
| KR20010042137A (ko) * | 1998-03-24 | 2001-05-25 | 알 브이 테이트 (로드니 비버스 테이트), 에이치 드로이. 씨. 지. 오닌크, 이. 에디, 산드라 웨드워즈 (에스 제이 에드워즈) | 화장용 보습 아이 트리트먼트 패드 |
| JPH11315007A (ja) | 1998-05-01 | 1999-11-16 | Yamakawa Boeki Kk | コラーゲン産生促進剤および皮膚外用剤 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190022114A (ko) | 2017-08-25 | 2019-03-06 | 대한민국(농촌진흥청장) | 연리초속 식물 추출물을 포함하는 항염증 활성을 갖는 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101146513B (zh) | 2011-01-12 |
| WO2006112224A1 (ja) | 2006-10-26 |
| HK1110793A1 (en) | 2008-07-25 |
| US20090061030A1 (en) | 2009-03-05 |
| JP2006282617A (ja) | 2006-10-19 |
| KR20070116943A (ko) | 2007-12-11 |
| CN101146513A (zh) | 2008-03-19 |
| JP4160964B2 (ja) | 2008-10-08 |
| US7820211B2 (en) | 2010-10-26 |
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