KR101186029B1 - 신경병증성 당뇨병성 족부 궤양을 치료하기 위한트레프로스티닐의 용도 - Google Patents

신경병증성 당뇨병성 족부 궤양을 치료하기 위한트레프로스티닐의 용도 Download PDF

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Publication number
KR101186029B1
KR101186029B1 KR1020067022940A KR20067022940A KR101186029B1 KR 101186029 B1 KR101186029 B1 KR 101186029B1 KR 1020067022940 A KR1020067022940 A KR 1020067022940A KR 20067022940 A KR20067022940 A KR 20067022940A KR 101186029 B1 KR101186029 B1 KR 101186029B1
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South Korea
Prior art keywords
treprostinil
pharmaceutical composition
foot ulcers
administration
derivative
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020067022940A
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English (en)
Korean (ko)
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KR20070007887A (ko
Inventor
마이클 웨이드
로저 앤드류 젭스
데보라 스트루우트맨
Original Assignee
유나이티드 쎄러퓨틱스 코포레이션
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Publication of KR20070007887A publication Critical patent/KR20070007887A/ko
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Publication of KR101186029B1 publication Critical patent/KR101186029B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
KR1020067022940A 2004-04-12 2005-04-12 신경병증성 당뇨병성 족부 궤양을 치료하기 위한트레프로스티닐의 용도 Expired - Fee Related KR101186029B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56115704P 2004-04-12 2004-04-12
US60/561,157 2004-04-12
PCT/US2005/012471 WO2005099680A2 (en) 2004-04-12 2005-04-12 Use of treprostinil to treat neuropathic diabetic foot ulcers

Publications (2)

Publication Number Publication Date
KR20070007887A KR20070007887A (ko) 2007-01-16
KR101186029B1 true KR101186029B1 (ko) 2012-09-27

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KR1020067022940A Expired - Fee Related KR101186029B1 (ko) 2004-04-12 2005-04-12 신경병증성 당뇨병성 족부 궤양을 치료하기 위한트레프로스티닐의 용도

Country Status (10)

Country Link
US (2) US7879909B2 (https=)
EP (1) EP1744739B1 (https=)
JP (1) JP2007532663A (https=)
KR (1) KR101186029B1 (https=)
CN (1) CN101287457B (https=)
AT (1) ATE462427T1 (https=)
CA (1) CA2562614C (https=)
DE (1) DE602005020269D1 (https=)
ES (1) ES2340939T3 (https=)
WO (1) WO2005099680A2 (https=)

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Also Published As

Publication number Publication date
US7879909B2 (en) 2011-02-01
WO2005099680A2 (en) 2005-10-27
US20110092599A1 (en) 2011-04-21
CN101287457A (zh) 2008-10-15
ES2340939T3 (es) 2010-06-11
KR20070007887A (ko) 2007-01-16
CA2562614A1 (en) 2005-10-27
US8563614B2 (en) 2013-10-22
DE602005020269D1 (de) 2010-05-12
CA2562614C (en) 2013-09-17
US20050282903A1 (en) 2005-12-22
WO2005099680A3 (en) 2005-12-01
JP2007532663A (ja) 2007-11-15
EP1744739A2 (en) 2007-01-24
CN101287457B (zh) 2011-11-16
ATE462427T1 (de) 2010-04-15
EP1744739B1 (en) 2010-03-31

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