ATE462427T1 - Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren - Google Patents

Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren

Info

Publication number
ATE462427T1
ATE462427T1 AT05735648T AT05735648T ATE462427T1 AT E462427 T1 ATE462427 T1 AT E462427T1 AT 05735648 T AT05735648 T AT 05735648T AT 05735648 T AT05735648 T AT 05735648T AT E462427 T1 ATE462427 T1 AT E462427T1
Authority
AT
Austria
Prior art keywords
treprostinil
foot ulcers
diabetic foot
treat neuropathic
neuropathic diabetic
Prior art date
Application number
AT05735648T
Other languages
English (en)
Inventor
Michael Wade
Roger Jeffs
Deborah Strootman
Original Assignee
United Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United Therapeutics Corp filed Critical United Therapeutics Corp
Application granted granted Critical
Publication of ATE462427T1 publication Critical patent/ATE462427T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
AT05735648T 2004-04-12 2005-04-12 Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren ATE462427T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56115704P 2004-04-12 2004-04-12
PCT/US2005/012471 WO2005099680A2 (en) 2004-04-12 2005-04-12 Use of treprostinil to treat neuropathic diabetic foot ulcers

Publications (1)

Publication Number Publication Date
ATE462427T1 true ATE462427T1 (de) 2010-04-15

Family

ID=34965914

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05735648T ATE462427T1 (de) 2004-04-12 2005-04-12 Verwendung von treprostinil zur behandlung von neuropathischen diabetischen fussgeschwüren

Country Status (10)

Country Link
US (2) US7879909B2 (de)
EP (1) EP1744739B1 (de)
JP (1) JP2007532663A (de)
KR (1) KR101186029B1 (de)
CN (1) CN101287457B (de)
AT (1) ATE462427T1 (de)
CA (1) CA2562614C (de)
DE (1) DE602005020269D1 (de)
ES (1) ES2340939T3 (de)
WO (1) WO2005099680A2 (de)

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JP6263604B2 (ja) 2013-03-25 2018-01-17 ユナイテッド セラピューティクス コーポレイション チオールリンカーを持つ、ペグ化型のプロスタサイクリン化合物の製造方法
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CA3209987A1 (en) 2021-03-03 2022-09-09 Hitesh Batra A dry powder composition of trestinil and its prodrug thereof and further comprising comprising (e)-3,6-bis[4-(n-carbonyl-2-propenyl)amidobutyl]-2,5-diketopiperazine (fdkp)
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Also Published As

Publication number Publication date
KR20070007887A (ko) 2007-01-16
CN101287457A (zh) 2008-10-15
EP1744739B1 (de) 2010-03-31
CA2562614C (en) 2013-09-17
US8563614B2 (en) 2013-10-22
ES2340939T3 (es) 2010-06-11
CA2562614A1 (en) 2005-10-27
CN101287457B (zh) 2011-11-16
WO2005099680A3 (en) 2005-12-01
US20050282903A1 (en) 2005-12-22
JP2007532663A (ja) 2007-11-15
DE602005020269D1 (de) 2010-05-12
US7879909B2 (en) 2011-02-01
EP1744739A2 (de) 2007-01-24
KR101186029B1 (ko) 2012-09-27
WO2005099680A2 (en) 2005-10-27
US20110092599A1 (en) 2011-04-21

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