KR101095287B1 - 조혈 줄기세포 및 이를 분리하는 방법 - Google Patents

조혈 줄기세포 및 이를 분리하는 방법 Download PDF

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KR101095287B1
KR101095287B1 KR1020057001388A KR20057001388A KR101095287B1 KR 101095287 B1 KR101095287 B1 KR 101095287B1 KR 1020057001388 A KR1020057001388 A KR 1020057001388A KR 20057001388 A KR20057001388 A KR 20057001388A KR 101095287 B1 KR101095287 B1 KR 101095287B1
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retinal
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KR20050027132A (ko
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프리들랜더마틴
오타니아쓰시
다실바카렌
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더 스크립스 리서치 인스티튜트
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0692—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020057001388A 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 분리하는 방법 Expired - Fee Related KR101095287B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39852202P 2002-07-25 2002-07-25
US60/398,522 2002-07-25
US46705103P 2003-05-02 2003-05-02
US60/467,051 2003-05-02
PCT/US2003/024839 WO2004010959A2 (en) 2002-07-25 2003-07-25 Hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith

Related Child Applications (1)

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KR1020117020059A Division KR20110102961A (ko) 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 사용한 신생혈관 안구 질환의 치료방법

Publications (2)

Publication Number Publication Date
KR20050027132A KR20050027132A (ko) 2005-03-17
KR101095287B1 true KR101095287B1 (ko) 2011-12-16

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KR1020057001388A Expired - Fee Related KR101095287B1 (ko) 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 분리하는 방법
KR1020117020059A Ceased KR20110102961A (ko) 2002-07-25 2003-07-25 조혈 줄기세포 및 이를 사용한 신생혈관 안구 질환의 치료방법

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Country Status (17)

Country Link
US (2) US7153501B2 (https=)
EP (1) EP1542536B1 (https=)
JP (2) JP2005538742A (https=)
KR (2) KR101095287B1 (https=)
CN (1) CN1307300C (https=)
AT (1) ATE536405T1 (https=)
AU (1) AU2003259687B2 (https=)
BR (1) BR0312920A (https=)
CA (1) CA2493122C (https=)
DK (1) DK1542536T3 (https=)
ES (1) ES2376866T3 (https=)
MX (1) MXPA05000972A (https=)
PL (1) PL216193B1 (https=)
PT (1) PT1542536E (https=)
RU (1) RU2331669C2 (https=)
WO (2) WO2004010959A2 (https=)
ZA (1) ZA200500682B (https=)

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US20060104962A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Transfected hematopoietic stem cells and methods of treatment of neovascular eye diseases therewith
WO2006031467A2 (en) * 2002-07-25 2006-03-23 The Scripps Research Institute Isolated lineage negative hematopoietic stem cells and methods of treatment therewith
US20060104963A1 (en) * 2002-07-25 2006-05-18 The Scripps Research Institute Treatment of cone cell degeneration with transfected lineage negative hematopoietic stem cells
BRPI0409861A (pt) * 2003-05-02 2006-05-16 Scripps Research Inst células- tronco hematopoiéticas e sua utilização em métodos de tratamento de doenças oculares neovasculares
WO2005042731A1 (en) * 2003-10-31 2005-05-12 Children's Medical Center Corporation Methods for purifying hematopoietic stem cells
RU2279886C2 (ru) * 2004-06-10 2006-07-20 Московский научно-исследовательский институт глазных болезней им. Гельмгольца Минздрава РФ Способ улучшения функциональной активности сетчатки при ее патологии различного генеза
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
ATE423842T1 (de) * 2004-08-13 2009-03-15 Medtronic Inc Isolation der endothelvorläuferzellen-untermengen und verfahren zu ihrer verwendung
JP2008512376A (ja) * 2004-09-03 2008-04-24 ザ・スクリプス・リサーチ・インステイチユート 単離された系統陰性造血幹細胞及びこれを用いた治療方法
DE102004055615A1 (de) * 2004-11-16 2006-05-18 Universitätsklinikum Hamburg-Eppendorf In vitro aus Knochenmarkstammzellen differenzierte Retina-spezifische Zellen, ihre Herstellung und Verwendung
CA2598029A1 (en) * 2005-02-24 2006-10-05 The Scripps Research Institute Isolated myeloid-like bone marrow cell populations and methods of treatment therewith
AU2006216473B2 (en) * 2005-02-24 2012-07-26 The Scripps Research Institute Method for the treatment of retinopathy of prematurity and related retinopathic diseases
US20070231306A1 (en) * 2005-02-24 2007-10-04 The Scripps Research Institute Isolated myeloid-like cell populations and methods of treatment therewith
AU2006216678B2 (en) * 2005-02-24 2011-11-17 The Scripps Research Institute Revascularization of ischemic retinal tissue and screening method therefor
JP4734636B2 (ja) * 2005-11-02 2011-07-27 国立大学法人 鹿児島大学 免疫染色法、及び当該免疫染色法を利用した細胞の評価方法
US20110076255A1 (en) 2005-11-07 2011-03-31 Pecora Andrew L Compositions and methods for treating progressive myocardial injury due to a vascular insufficiency
MY147516A (en) 2005-11-07 2012-12-31 Amorcyte Inc Compositions and method of vascular injury repair cross-reference to related applications
US8637005B2 (en) 2005-11-07 2014-01-28 Amorcyte, Inc. Compositions and methods of vascular injury repair
EP2422802A3 (en) 2006-03-07 2013-03-06 Geeta Shroff Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
KR100757265B1 (ko) * 2006-04-27 2007-09-10 (주) 차바이오텍 제대혈 유래 줄기 세포를 포함하는 요실금 치료용 조성물
JP6041456B2 (ja) * 2006-07-12 2016-12-07 メゾブラスト，インコーポレーテッド 過剰新生血管形成の治療
WO2008057580A2 (en) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Materials and methods for treating and managing angiogenesis-mediated diseases
US20100098675A1 (en) * 2008-05-30 2010-04-22 Nikolai Tankovich Methods for reducing the side effects of ophthalmic laser surgery
BRPI0919020B8 (pt) * 2008-09-12 2021-05-25 Cryopraxis Criobiologia Ltda uso de células de linhagem monocitária enriquecidas para tratar isquemia e para tratar angina pectoris
CN102245189B (zh) 2008-12-03 2015-06-17 阿莫塞特公司 改善梗死区灌注的组合物以及血管损伤修复方法
RU2428956C2 (ru) * 2009-07-13 2011-09-20 Александр Дмитриевич Ромащенко Способ лечения атрофии зрительного нерва посредством трансплантации аутологичных стволовых клеток
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Also Published As

Publication number Publication date
JP5385219B2 (ja) 2014-01-08
EP1542536B1 (en) 2011-12-07
PT1542536E (pt) 2012-02-14
KR20050027132A (ko) 2005-03-17
WO2004098499A3 (en) 2005-10-06
EP1542536A2 (en) 2005-06-22
RU2331669C2 (ru) 2008-08-20
WO2004010959A3 (en) 2005-04-07
JP2005538742A (ja) 2005-12-22
ATE536405T1 (de) 2011-12-15
KR20110102961A (ko) 2011-09-19
BR0312920A (pt) 2007-07-10
DK1542536T3 (da) 2012-01-23
PL374868A1 (en) 2005-11-14
PL216193B1 (pl) 2014-03-31
AU2003259687B2 (en) 2009-10-29
RU2005105065A (ru) 2005-09-10
CA2493122C (en) 2012-11-27
ES2376866T3 (es) 2012-03-20
CN1307300C (zh) 2007-03-28
CN1688196A (zh) 2005-10-26
CA2493122A1 (en) 2004-02-05
US20040197902A1 (en) 2004-10-07
WO2004010959A2 (en) 2004-02-05
AU2003259687A1 (en) 2004-02-16
EP1542536A4 (en) 2007-05-16
US7153501B2 (en) 2006-12-26
ZA200500682B (en) 2006-07-26
US20070116685A1 (en) 2007-05-24
JP2010285434A (ja) 2010-12-24
WO2004098499A2 (en) 2004-11-18
MXPA05000972A (es) 2005-09-12

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