KR100735788B1 - 일반 염을 함유하는 목시플록사신 제형 - Google Patents

일반 염을 함유하는 목시플록사신 제형 Download PDF

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Publication number
KR100735788B1
KR100735788B1 KR1020027001575A KR20027001575A KR100735788B1 KR 100735788 B1 KR100735788 B1 KR 100735788B1 KR 1020027001575 A KR1020027001575 A KR 1020027001575A KR 20027001575 A KR20027001575 A KR 20027001575A KR 100735788 B1 KR100735788 B1 KR 100735788B1
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KR
South Korea
Prior art keywords
moxifloxacin
sodium chloride
formulation
solution
active compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020027001575A
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English (en)
Korean (ko)
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KR20020022794A (ko
Inventor
베른트 퀸
한스-프리드리히 말러
미하엘 아이젤
Original Assignee
바이엘 헬스케어 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7917417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100735788(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 바이엘 헬스케어 아게 filed Critical 바이엘 헬스케어 아게
Publication of KR20020022794A publication Critical patent/KR20020022794A/ko
Application granted granted Critical
Publication of KR100735788B1 publication Critical patent/KR100735788B1/ko
Assigned to 바이엘 파마 악티엔게젤샤프트 reassignment 바이엘 파마 악티엔게젤샤프트 권리의 전부이전등록 Assignors: 바이엘 헬스케어 아게
Assigned to 바이엘 인텔렉쳐 프로퍼티 게엠베하 reassignment 바이엘 인텔렉쳐 프로퍼티 게엠베하 권리의 전부이전등록 Assignors: 바이엘 파마 악티엔게젤샤프트
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020027001575A 1999-08-06 2000-07-25 일반 염을 함유하는 목시플록사신 제형 Expired - Lifetime KR100735788B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19937116A DE19937116A1 (de) 1999-08-06 1999-08-06 Moxifloxacin Kochsalzformulierung
DE19937116.4 1999-08-06

Publications (2)

Publication Number Publication Date
KR20020022794A KR20020022794A (ko) 2002-03-27
KR100735788B1 true KR100735788B1 (ko) 2007-07-06

Family

ID=7917417

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020027001575A Expired - Lifetime KR100735788B1 (ko) 1999-08-06 2000-07-25 일반 염을 함유하는 목시플록사신 제형

Country Status (40)

Country Link
US (1) US6548079B1 (https=)
EP (1) EP1206281B1 (https=)
JP (1) JP5522877B2 (https=)
KR (1) KR100735788B1 (https=)
CN (1) CN1246039C (https=)
AR (1) AR025001A1 (https=)
AT (1) ATE270104T1 (https=)
AU (1) AU771058B2 (https=)
BG (1) BG65304B1 (https=)
BR (1) BRPI0013010B8 (https=)
CA (1) CA2378424C (https=)
CO (1) CO5190677A1 (https=)
CU (1) CU23367A3 (https=)
CZ (1) CZ298768B6 (https=)
DE (2) DE19937116A1 (https=)
DK (1) DK1206281T3 (https=)
EE (1) EE04771B1 (https=)
ES (1) ES2223549T3 (https=)
GT (1) GT200000123A (https=)
HK (1) HK1049615B (https=)
HN (1) HN2000000115A (https=)
HR (1) HRP20020198B1 (https=)
HU (1) HU229571B1 (https=)
IL (2) IL147553A0 (https=)
MA (1) MA25427A1 (https=)
MX (1) MXPA02001254A (https=)
MY (1) MY125356A (https=)
NO (1) NO320743B1 (https=)
NZ (1) NZ516969A (https=)
PE (1) PE20010400A1 (https=)
PL (1) PL198132B1 (https=)
PT (1) PT1206281E (https=)
RU (1) RU2260429C9 (https=)
SI (1) SI1206281T1 (https=)
SK (1) SK285650B6 (https=)
TW (1) TWI238719B (https=)
UA (1) UA72268C2 (https=)
UY (1) UY26269A1 (https=)
WO (1) WO2001010465A1 (https=)
ZA (1) ZA200200215B (https=)

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DE19937116A1 (de) 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE10218328A1 (de) 2002-03-05 2003-09-25 Humboldt Uni Zu Berlin Medizin Mittel zur präventiven Therapie nach akutem Schlaganfall
US20040197408A1 (en) * 2002-12-30 2004-10-07 Angiotech International Ag Amino acids in micelle preparation
WO2006015545A1 (fr) * 2004-08-11 2006-02-16 Shenzhen Tys R & D Co., Ltd. Capsule de gelatine de moxifloxacin et procede pour sa preparation
JO2752B1 (en) * 2005-06-28 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO3270B1 (ar) * 2005-06-28 2018-09-16 Janssen Pharmaceutica Nv مشتقات كوينولين بصفة عوامل مضادة للبكتيريا
DE102006031175A1 (de) * 2006-07-06 2008-01-10 Bayer Healthcare Ag Wässrige Arzneimittelformulierung von 4-[((4-Carboxybutyl)-(2[(4-phenethyl-benzyl)oxy]-phenethyl)amino)methyl]benzoesäur
US7537532B2 (en) * 2007-05-16 2009-05-26 Young Carl D Handle for implement and method
CN101787022B (zh) * 2009-10-09 2012-08-22 浙江医药股份有限公司新昌制药厂 一种喹啉羧酸盐酸盐一水合物晶型及其制备方法
WO2011086577A2 (en) * 2010-01-12 2011-07-21 Msn Laboratories Limited Pharmaceutical composition of moxifloxacin and its pharmaceutically acceptable salts
CN101836950A (zh) * 2010-03-12 2010-09-22 陕西合成药业有限公司 一种盐酸莫西沙星葡萄糖注射液及其制备方法和用途
CN101972257B (zh) * 2010-09-10 2015-08-05 杭州民生药业有限公司 一种含有莫西沙星的药物组合物
CN102100666B (zh) * 2011-01-17 2012-07-18 南京新港医药有限公司 一种新的盐酸莫西沙星注射剂
CN102093349B (zh) * 2011-01-17 2012-03-07 南京新港医药有限公司 一种工业化生产盐酸莫西沙星的方法
CN102688183B (zh) * 2011-03-21 2016-04-06 重庆医药工业研究院有限责任公司 一种稳定的盐酸莫西沙星注射剂
KR101435244B1 (ko) * 2011-04-12 2014-08-29 씨제이헬스케어 주식회사 목시플록사신 수성 제형 및 이의 제조방법
KR101327904B1 (ko) * 2011-08-16 2013-11-13 대한약품공업 주식회사 목시플록사신 염산염의 주사제형
RU2472507C1 (ru) * 2012-02-01 2013-01-20 Закрытое акционерное общество "Брынцалов-А" Водный состав на основе моксифлоксацина для парентерального введения
CN102600093B (zh) * 2012-04-11 2013-06-05 南京优科生物医药有限公司 一种莫西沙星片剂及其制备方法
GR1008168B (el) 2013-03-14 2014-04-08 "Φαρματεν Α.Β.Ε.Ε.", Παρεντερικο σκευασμα αντιβακτηριακου παραγοντα φθοριοκινολονης και μεθοδος για την παρασκευη αυτου
CN103191056B (zh) * 2013-04-28 2014-10-22 南京海融医药科技有限公司 莫西沙星的口服液体制剂及其制备方法和应用
WO2015093669A1 (ko) * 2013-12-20 2015-06-25 씨제이헬스케어 주식회사 목시플록사신 수성 제형 및 이의 제조방법
CN103976944A (zh) * 2014-05-16 2014-08-13 成都青山利康药业有限公司 一种盐酸莫西沙星氯化钠注射液
CN104771359A (zh) * 2015-04-02 2015-07-15 南京正大天晴制药有限公司 一种稳定的盐酸莫西沙星注射液
CN105640876B (zh) * 2016-01-07 2019-04-12 天津红日药业股份有限公司 一种盐酸莫西沙星氯化钠注射液的制备工艺
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
EP3578182A1 (en) * 2018-06-05 2019-12-11 Bayer Animal Health GmbH Formulations containing triazinones and iron with a low amount of free iron ions
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
CN111388415A (zh) * 2020-03-19 2020-07-10 石家庄四药有限公司 一种盐酸莫西沙星氯化钠注射液及其制备方法
CN116490211A (zh) 2020-10-29 2023-07-25 株式会社泰俊制药 眼用组合物
CN115944586B (zh) * 2023-01-17 2024-12-17 江苏睿实生物科技有限公司 一种盐酸莫西沙星制剂的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607942A (en) 1988-07-15 1997-03-04 Bayer Aktiengesellschaft 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives
WO2000018386A2 (en) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Antibiotic compositions for treatment of the eye, ear and nose

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DE3537761A1 (de) * 1985-10-24 1987-04-30 Bayer Ag Infusionsloesungen der 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-chinolin-3-carbonsaeure
JPH01258620A (ja) * 1988-04-08 1989-10-16 Dai Ichi Seiyaku Co Ltd 耳疾患用局所製剤
EP0470252A4 (en) * 1989-04-28 1992-12-02 Daiichi Pharmaceutical Co., Ltd. Anti-hiv drug
AU647772B2 (en) 1989-12-29 1994-03-31 Abbott Laboratories Quinolone carboxylic acid--metal ion--acid complexes
US5084276A (en) 1990-01-05 1992-01-28 Abbott Laboratories Quinolone carboxylic acid compositions with polymeric additive to reduce vein irritation
FR2681863B1 (fr) 1991-09-27 1995-02-03 Rhone Dpc Europ Solution de sparfloxacine sa preparation et sel la constituant.
DE4306417A1 (de) * 1993-03-02 1994-09-08 Grace Gmbh Vorrichtung und Verfahren zum Verbrennen oxidierbarer Bestandteile in einem zu reinigenden Trägergas
CA2152828A1 (en) * 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
KR960000223A (ko) 1994-06-08 1996-01-25 김정순 신규한 피리돈 카르복실산 화합물을 함유한 수용액 및 이의 제조방법
CZ293747B6 (cs) * 1995-12-21 2004-07-14 Pfizer Inc. Vodný farmaceutický roztok vhodný pro injekční podávání hostiteli a jeho použití
JPH1192375A (ja) * 1997-09-25 1999-04-06 Morinaga Milk Ind Co Ltd ニューキノロン系抗菌剤の抗菌性を増強させる抗菌剤
TR200101310T2 (tr) * 1998-11-10 2001-10-22 Bayer Aktiengesellschaft Farmasötik moksifloksasin preparatı.
DE19937116A1 (de) 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
DE19937115A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Wäßrige Arzneimittelformulierung von Moxifloxacin oder Salzen davon

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
US5607942A (en) 1988-07-15 1997-03-04 Bayer Aktiengesellschaft 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives
WO2000018386A2 (en) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Antibiotic compositions for treatment of the eye, ear and nose

Also Published As

Publication number Publication date
JP5522877B2 (ja) 2014-06-18
ES2223549T3 (es) 2005-03-01
JP2003506416A (ja) 2003-02-18
HRP20020198B1 (hr) 2011-02-28
RU2260429C2 (ru) 2005-09-20
KR20020022794A (ko) 2002-03-27
AU6159600A (en) 2001-03-05
CU23367A3 (es) 2009-04-14
RU2260429C9 (ru) 2006-03-27
HK1049615A1 (en) 2003-05-23
CO5190677A1 (es) 2002-08-29
NO20020526L (no) 2002-02-01
HK1049615B (zh) 2006-11-10
PL198132B1 (pl) 2008-05-30
HN2000000115A (es) 2001-02-02
NO320743B1 (no) 2006-01-23
UA72268C2 (uk) 2005-02-15
UY26269A1 (es) 2001-03-16
NZ516969A (en) 2004-03-26
DK1206281T3 (da) 2004-10-25
CN1246039C (zh) 2006-03-22
CA2378424A1 (en) 2001-02-15
EP1206281B1 (de) 2004-06-30
ATE270104T1 (de) 2004-07-15
MXPA02001254A (es) 2002-08-12
BG106366A (en) 2002-08-30
PT1206281E (pt) 2004-10-29
NO20020526D0 (no) 2002-02-01
CA2378424C (en) 2009-02-17
US6548079B1 (en) 2003-04-15
CZ2002458A3 (cs) 2002-06-12
MA25427A1 (fr) 2002-04-01
BR0013010B1 (pt) 2013-12-10
BG65304B1 (bg) 2008-01-31
MY125356A (en) 2006-07-31
TWI238719B (en) 2005-09-01
HUP0203619A2 (hu) 2003-02-28
AR025001A1 (es) 2002-11-06
EE04771B1 (et) 2007-02-15
ZA200200215B (en) 2002-09-25
AU771058B2 (en) 2004-03-11
EE200200060A (et) 2003-04-15
SK1682002A3 (en) 2002-06-04
PL353405A1 (en) 2003-11-17
HUP0203619A3 (en) 2003-12-29
BR0013010A (pt) 2002-04-30
DE50006974D1 (de) 2004-08-05
CZ298768B6 (cs) 2008-01-23
CN1368891A (zh) 2002-09-11
SK285650B6 (sk) 2007-05-03
IL147553A0 (en) 2002-08-14
WO2001010465A1 (de) 2001-02-15
DE19937116A1 (de) 2001-02-08
IL147553A (en) 2006-09-05
EP1206281A1 (de) 2002-05-22
SI1206281T1 (en) 2004-12-31
BRPI0013010B8 (pt) 2021-05-25
HU229571B1 (en) 2014-02-28
HRP20020198A2 (en) 2004-02-29
GT200000123A (es) 2000-08-01
PE20010400A1 (es) 2001-06-11

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