KR100646716B1 - Ａｔ-1 또는 ａｔ-2 수용체의 증가와 관련된 질환의치료에 있어서 ａｔ-1 수용체 길항제 또는 ａｔ-2 수용체조절제의 용도 - Google Patents

Ａｔ-1 또는 ａｔ-2 수용체의 증가와 관련된 질환의치료에 있어서 ａｔ-1 수용체 길항제 또는 ａｔ-2 수용체조절제의 용도 Download PDF

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KR100646716B1
KR100646716B1 KR1020017007996A KR20017007996A KR100646716B1 KR 100646716 B1 KR100646716 B1 KR 100646716B1 KR 1020017007996 A KR1020017007996 A KR 1020017007996A KR 20017007996 A KR20017007996 A KR 20017007996A KR 100646716 B1 KR100646716 B1 KR 100646716B1
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receptor
valsartan
receptors
microcrystalline cellulose
compressed tablet
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Expired - Fee Related
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English (en)
Korean (ko)
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KR20010089681A (ko
Inventor
질리언 로즈마리 불록
마크 데가스파로
사비나 마리아 간터
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노파르티스 아게
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Priority claimed from EP98811258A external-priority patent/EP1013273A1/en
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020017007996A 1998-12-23 1999-12-22 Ａｔ-1 또는 ａｔ-2 수용체의 증가와 관련된 질환의치료에 있어서 ａｔ-1 수용체 길항제 또는 ａｔ-2 수용체조절제의 용도 Expired - Fee Related KR100646716B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP98811258.7 1998-12-23
EP98811257 1998-12-23
EP98811258A EP1013273A1 (en) 1998-12-23 1998-12-23 Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors
EP98811257.9 1998-12-23

Publications (2)

Publication Number Publication Date
KR20010089681A KR20010089681A (ko) 2001-10-08
KR100646716B1 true KR100646716B1 (ko) 2006-11-17

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KR1020017007996A Expired - Fee Related KR100646716B1 (ko) 1998-12-23 1999-12-22 Ａｔ-1 또는 ａｔ-2 수용체의 증가와 관련된 질환의치료에 있어서 ａｔ-1 수용체 길항제 또는 ａｔ-2 수용체조절제의 용도

Country Status (26)

Country Link
EP (3) EP2298298A3 (https=)
JP (2) JP2002533390A (https=)
KR (1) KR100646716B1 (https=)
CN (2) CN1304000C (https=)
AT (2) ATE524176T1 (https=)
AU (4) AU3043000A (https=)
BR (1) BR9916576A (https=)
CA (2) CA2351357A1 (https=)
CY (2) CY1106581T1 (https=)
CZ (2) CZ297795B6 (https=)
DE (1) DE69935249T2 (https=)
DK (2) DK1588706T3 (https=)
ES (2) ES2373556T3 (https=)
HK (1) HK1038888B (https=)
HU (1) HUP0104780A3 (https=)
ID (1) ID29856A (https=)
IL (5) IL143233A0 (https=)
NO (2) NO328775B1 (https=)
NZ (3) NZ587909A (https=)
PL (1) PL199100B1 (https=)
PT (2) PT1140071E (https=)
RU (3) RU2271809C2 (https=)
SI (2) SI1588706T1 (https=)
SK (1) SK9132001A3 (https=)
TR (7) TR200200764T2 (https=)
WO (1) WO2000038676A1 (https=)

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CN102266307B (zh) * 2011-08-01 2012-10-24 海南锦瑞制药股份有限公司 一种缬沙坦胶囊及其制备方法
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EA018867B1 (ru) * 2012-11-01 2013-11-29 Лаборатория Тютор С.А.С.И.Ф.И.А. Способ получения фармацевтической композиции и продукт способа
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TR200605471T2 (tr) 2006-11-21
WO2000038676A1 (en) 2000-07-06
CA2351357A1 (en) 2000-07-06
EP1588706B1 (en) 2011-09-14
NO328775B1 (no) 2010-05-10
PT1140071E (pt) 2007-05-31
TR200805741T2 (tr) 2008-10-21
AU2006203077B2 (en) 2009-10-08
AU2003266433A1 (en) 2004-01-08
TR200605472T1 (tr) 2007-02-21
TR200805740T1 (tr) 2010-06-21
RU2361575C2 (ru) 2009-07-20
ATE354364T1 (de) 2007-03-15
EP1140071B1 (en) 2007-02-21
DE69935249D1 (de) 2007-04-05
ES2373556T3 (es) 2012-02-06
SK9132001A3 (en) 2002-01-07
NO20100041L (no) 2001-08-16
HK1038888A1 (en) 2002-04-04
EP1588706A3 (en) 2005-12-07
PT1588706E (pt) 2011-12-21
CN1304000C (zh) 2007-03-14
CY1112395T1 (el) 2015-12-09
CY1106581T1 (el) 2012-01-25
DK1588706T3 (da) 2012-01-16
JP5254258B2 (ja) 2013-08-07
EP1140071A1 (en) 2001-10-10
SI1140071T1 (sl) 2007-08-31
ID29856A (id) 2001-10-18
TR200200764T2 (tr) 2002-07-22
HK1038888B (en) 2007-09-21
NZ553010A (en) 2008-09-26
EP2298298A3 (en) 2011-05-11
CZ297795B6 (cs) 2007-03-28
ATE524176T1 (de) 2011-09-15
DE69935249T2 (de) 2007-10-31
RU2005124363A (ru) 2007-02-10
DK1140071T3 (da) 2007-06-04
KR20010089681A (ko) 2001-10-08
RU2271809C2 (ru) 2006-03-20
TR200805275T2 (tr) 2008-09-22
NZ511938A (en) 2004-02-27
CZ20012306A3 (cs) 2001-12-12
HUP0104780A2 (hu) 2002-04-29
PL349424A1 (en) 2002-07-29
CA2622805C (en) 2011-05-10
EP1588706A2 (en) 2005-10-26
IL179015A0 (en) 2007-03-08
IL143233A0 (en) 2002-04-21
ES2281978T3 (es) 2007-10-01
AU2009220022B2 (en) 2011-11-03
RU2008143545A (ru) 2010-05-10
SI1588706T1 (sl) 2012-01-31
IL179017A0 (en) 2007-03-08
IL179016A0 (en) 2007-03-08
TR200101784T2 (tr) 2001-10-22
JP2002533390A (ja) 2002-10-08
AU3043000A (en) 2000-07-31
NO20013143D0 (no) 2001-06-22
NZ587909A (en) 2012-05-25
CN1636561A (zh) 2005-07-13
AU2006203077A1 (en) 2006-08-10
JP2010090169A (ja) 2010-04-22
HUP0104780A3 (en) 2002-11-28
AU2003266433B2 (en) 2006-08-10
AU2009220022A1 (en) 2009-10-15
CZ293257B6 (cs) 2004-03-17
EP2298298A2 (en) 2011-03-23
IL143233A (en) 2007-07-24
CA2622805A1 (en) 2000-07-06
PL199100B1 (pl) 2008-08-29
CN1331590A (zh) 2002-01-16
BR9916576A (pt) 2001-10-02
NO20013143L (no) 2001-08-16

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