KR100540720B1 - 신규형의 ｓ-오메프라졸 - Google Patents

신규형의 ｓ-오메프라졸 Download PDF

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Publication number
KR100540720B1
KR100540720B1 KR1019997011106A KR19997011106A KR100540720B1 KR 100540720 B1 KR100540720 B1 KR 100540720B1 KR 1019997011106 A KR1019997011106 A KR 1019997011106A KR 19997011106 A KR19997011106 A KR 19997011106A KR 100540720 B1 KR100540720 B1 KR 100540720B1
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South Korea
Prior art keywords
omeprazole
magnesium salt
magnesium
salt
trihydrate
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1019997011106A
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English (en)
Korean (ko)
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KR20010013126A (ko
Inventor
한나 코튼
안더즈 크론스트룀
안더즈 마트슨
에바 묄러
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아스트라제네카 악티에볼라그
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Application filed by 아스트라제네카 악티에볼라그 filed Critical 아스트라제네카 악티에볼라그
Priority to KR10-2005-7006896A priority Critical patent/KR100527804B1/ko
Publication of KR20010013126A publication Critical patent/KR20010013126A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Glass Compositions (AREA)
KR1019997011106A 1997-05-30 1998-05-25 신규형의 ｓ-오메프라졸 Expired - Lifetime KR100540720B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR10-2005-7006896A KR100527804B1 (ko) 1997-05-30 1998-05-25 Ｓ-오메프라졸의 칼륨염

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9702065-5 1997-05-30
SE9702065A SE510650C2 (sv) 1997-05-30 1997-05-30 Ny förening
PCT/SE1998/000974 WO1998054171A1 (en) 1997-05-30 1998-05-25 Novel form of s-omeprazole

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR10-2005-7006896A Division KR100527804B1 (ko) 1997-05-30 1998-05-25 Ｓ-오메프라졸의 칼륨염

Publications (2)

Publication Number Publication Date
KR20010013126A KR20010013126A (ko) 2001-02-26
KR100540720B1 true KR100540720B1 (ko) 2006-01-12

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ID=20407186

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019997011106A Expired - Lifetime KR100540720B1 (ko) 1997-05-30 1998-05-25 신규형의 ｓ-오메프라졸
KR10-2005-7006896A Expired - Lifetime KR100527804B1 (ko) 1997-05-30 1998-05-25 Ｓ-오메프라졸의 칼륨염

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR10-2005-7006896A Expired - Lifetime KR100527804B1 (ko) 1997-05-30 1998-05-25 Ｓ-오메프라졸의 칼륨염

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Country Link
US (6) US6369085B1 (https=)
EP (2) EP1273581B1 (https=)
JP (2) JP4002303B2 (https=)
KR (2) KR100540720B1 (https=)
CN (1) CN1161351C (https=)
AR (2) AR012717A1 (https=)
AT (2) ATE291574T1 (https=)
AU (1) AU722839B2 (https=)
BR (1) BR9809509A (https=)
CA (2) CA2521391C (https=)
CY (1) CY2012029I1 (https=)
CZ (1) CZ297585B6 (https=)
DE (3) DE69829511T2 (https=)
DK (2) DK0984957T3 (https=)
DZ (1) DZ2495A1 (https=)
EE (1) EE03875B1 (https=)
EG (1) EG24291A (https=)
ES (2) ES2195345T7 (https=)
HR (1) HRP980263B1 (https=)
HU (1) HU225987B1 (https=)
ID (1) ID29306A (https=)
IL (1) IL132947A0 (https=)
IS (2) IS2142B (https=)
LU (2) LU91871I2 (https=)
MA (1) MA26500A1 (https=)
ME (3) MEP18008A (https=)
MY (2) MY120745A (https=)
NO (3) NO317518B1 (https=)
NZ (1) NZ500991A (https=)
PL (1) PL193546B1 (https=)
PT (2) PT1273581E (https=)
RS (2) RS50005B (https=)
RU (1) RU2184115C2 (https=)
SA (2) SA05260296B1 (https=)
SE (1) SE510650C2 (https=)
SI (2) SI1273581T1 (https=)
SK (2) SK285137B6 (https=)
TN (1) TNSN98074A1 (https=)
TR (1) TR199902934T2 (https=)
TW (1) TW538040B (https=)
UA (1) UA60334C2 (https=)
WO (1) WO1998054171A1 (https=)
ZA (1) ZA984179B (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101303813B1 (ko) * 2007-04-16 2013-09-04 에스케이케미칼주식회사 라세믹 오메프라졸로부터 에스오메프라졸의 개선된제조방법
KR102432084B1 (ko) 2021-11-16 2022-08-12 알리코제약(주) S-오메프라졸을 함유하는 안정성이 개선되고 소형화된 정제

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* Cited by examiner, † Cited by third party
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US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
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US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
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US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
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US7169793B2 (en) 2002-06-27 2007-01-30 Dr. Reddy's Laboratories Limited Process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
DE60311809T2 (de) * 2002-06-27 2007-11-22 Dr. Reddy's Laboratories Ltd. Verfahren zur herstellung optisch reiner oder optisch angereicherter sulfoxidverbindungen einschliesslich amorphen esomeprazols und dessen salze
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WO2004089935A1 (en) * 2003-04-10 2004-10-21 Hetero Drugs Limitd Novel crystalline forms of s-omeprazole magnesium
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CN102241668B (zh) * 2010-05-11 2015-11-25 中国科学院成都有机化学有限公司 S-奥美拉唑盐
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CN102757421A (zh) * 2011-04-29 2012-10-31 江苏正大天晴药业股份有限公司 埃索美拉唑的纯化方法
CN104844577A (zh) * 2011-07-31 2015-08-19 连云港润众制药有限公司 埃索美拉唑镁的晶型
CN102924435B (zh) * 2011-11-25 2014-06-25 成都自豪药业有限公司 S-奥美拉唑镁盐的晶型及其制备方法
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CN102584792B (zh) * 2012-01-06 2014-06-11 南京优科生物医药研究有限公司 制备高纯度的埃索美拉唑盐的方法
CN102993184A (zh) * 2013-01-08 2013-03-27 湖南方盛制药股份有限公司 一种埃索美拉唑及其镁盐三水合物的制备方法
CN104250243B (zh) * 2013-06-27 2016-12-28 四川国为制药有限公司 一种埃索美拉唑镁二水合物a晶型的制备方法
CN103570686B (zh) * 2013-10-14 2015-04-01 哈药集团技术中心 一种埃索美拉唑钠的合成及精制工艺
CN104725357A (zh) * 2013-12-24 2015-06-24 苏州联友制药技术有限公司 一种埃索美拉唑镁二水合物晶型b的制备方法
FR3018812A1 (fr) 2014-03-21 2015-09-25 Minakem Nouvelle phase intermediaire de la forme a du sel de magnesium dihydrate d'un enantiomere de l'omeprazole
CN104447699A (zh) * 2014-12-10 2015-03-25 哈药集团技术中心 一种埃索美拉唑镁三水合物的制备方法
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JP2025532389A (ja) 2022-10-04 2025-09-29 ザビリュク，アルセニー 大動脈弁の石灰化の抑制
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