KR100524358B1 - 담즙산을 가진 청정 수용액 제형의 제조방법 - Google Patents
담즙산을 가진 청정 수용액 제형의 제조방법 Download PDFInfo
- Publication number
- KR100524358B1 KR100524358B1 KR10-2001-7001037A KR20017001037A KR100524358B1 KR 100524358 B1 KR100524358 B1 KR 100524358B1 KR 20017001037 A KR20017001037 A KR 20017001037A KR 100524358 B1 KR100524358 B1 KR 100524358B1
- Authority
- KR
- South Korea
- Prior art keywords
- acid
- solution
- bile
- aqueous solution
- clean
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9406998P | 1998-07-24 | 1998-07-24 | |
| US60/094,069 | 1998-07-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010074748A KR20010074748A (ko) | 2001-08-09 |
| KR100524358B1 true KR100524358B1 (ko) | 2005-10-26 |
Family
ID=22242686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR10-2001-7001037A Expired - Lifetime KR100524358B1 (ko) | 1998-07-24 | 1999-07-20 | 담즙산을 가진 청정 수용액 제형의 제조방법 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6251428B1 (enExample) |
| EP (1) | EP1113785B1 (enExample) |
| JP (2) | JP4790123B2 (enExample) |
| KR (1) | KR100524358B1 (enExample) |
| CN (1) | CN1205922C (enExample) |
| AT (1) | ATE292956T1 (enExample) |
| AU (1) | AU758679B2 (enExample) |
| BR (1) | BR9912395A (enExample) |
| CA (1) | CA2338457C (enExample) |
| DE (1) | DE69924740T2 (enExample) |
| ES (1) | ES2238843T3 (enExample) |
| ID (1) | ID29632A (enExample) |
| IL (2) | IL140986A0 (enExample) |
| PT (1) | PT1113785E (enExample) |
| RU (1) | RU2224523C2 (enExample) |
| WO (1) | WO2000004875A2 (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100314496B1 (ko) | 1998-05-28 | 2001-11-22 | 윤동진 | 항혈전성이 있는 헤파린 유도체, 그의 제조방법 및 용도 |
| US7303768B2 (en) * | 1998-07-24 | 2007-12-04 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| US20050158408A1 (en) * | 1998-07-24 | 2005-07-21 | Yoo Seo H. | Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof |
| US20070072828A1 (en) * | 1998-07-24 | 2007-03-29 | Yoo Seo H | Bile preparations for colorectal disorders |
| US7772220B2 (en) * | 2004-10-15 | 2010-08-10 | Seo Hong Yoo | Methods and compositions for reducing toxicity of a pharmaceutical compound |
| DE19834814A1 (de) * | 1998-08-01 | 2000-02-03 | Beiersdorf Ag | Kosmetische und dermatologische Zubereitungen mit einem wirksamen Gehalt an Gallensäuren, ihren Salzen und/oder ihren Derivaten |
| US6417179B1 (en) * | 1998-10-13 | 2002-07-09 | Craig G. Burkhart | Ear wax solution |
| GB2355009A (en) * | 1999-07-30 | 2001-04-11 | Univ Glasgow | Peptides conjugated to bile acids/salts |
| AU2006203315B2 (en) * | 2000-02-04 | 2008-08-28 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| EP1255566A2 (en) * | 2000-02-04 | 2002-11-13 | Seo Hong Yoo | Preparation of aqueous clear solution dosage forms with bile acids |
| DE60028339T2 (de) * | 2000-04-20 | 2007-05-10 | Bioprogress S.P.A. | Verfahren zur Herstellung ursodeoxycholsäure enthaltender pharmazeutischer Zusammensetzungen in flüssiger Form |
| FR2809310B1 (fr) * | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
| KR100368936B1 (ko) * | 2000-10-04 | 2003-01-24 | 주식회사 대웅 | 우루소데옥시콜린산을 함유한 환경호르몬 독성의 예방 및치료제 |
| GB0103046D0 (en) * | 2001-02-07 | 2001-03-21 | Novartis Ag | Organic Compounds |
| MXPA03011538A (es) * | 2001-06-14 | 2004-03-09 | Otsuka Pharma Co Ltd | Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal. |
| US6702850B1 (en) * | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
| US20080026077A1 (en) * | 2002-11-12 | 2008-01-31 | John Hilfinger | Methods and compositions of gene delivery agents for systemic and local therapy |
| US7145125B2 (en) | 2003-06-23 | 2006-12-05 | Advanced Optical Technologies, Llc | Integrating chamber cone light using LED sources |
| ES2660172T3 (es) * | 2004-05-19 | 2018-03-21 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Composición inyectable que comprende desoxicolato de sodio |
| US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
| US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| US7906137B2 (en) * | 2004-05-21 | 2011-03-15 | Mediplex Corporation, Korea | Delivery agents for enhancing mucosal absorption of therapeutic agents |
| CN101035541B (zh) * | 2004-08-30 | 2012-05-30 | 柳署弘 | 溶解的udca在局灶缺血模型中的神经保护作用 |
| AU2005295541B2 (en) | 2004-10-15 | 2011-02-17 | Seo Hong Yoo | Methods and compositions for reducing toxicity of a pharmaceutical compound |
| CN101048164B (zh) * | 2004-11-01 | 2012-05-09 | 柳署弘 | 降低肌萎缩性侧索硬化中神经变性的组合物 |
| DE602005025391D1 (de) * | 2004-11-01 | 2011-01-27 | Seo Hong Yoo | Verfahren und zusammensetzungen zur verringerung der neurodegeneration bei amyotrophischer lateralsklerose |
| SI2730277T1 (sl) | 2004-12-22 | 2020-07-31 | Nitto Denko Corporation | Nosilec zdravila in komplet za nosilec zdravila za zaviranje fibroze |
| US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| CN101023940A (zh) * | 2006-02-20 | 2007-08-29 | 郝守祝 | 一种紫杉烷类化合物的药用组合物、制备方法及用途 |
| CN101547699A (zh) * | 2006-09-15 | 2009-09-30 | 柳署弘 | 用于结肠直肠病症的胆汁制剂 |
| TWI407971B (zh) | 2007-03-30 | 2013-09-11 | Nitto Denko Corp | Cancer cells and tumor-related fibroblasts |
| ITMI20071573A1 (it) * | 2007-07-31 | 2009-02-01 | Acraf | Composizione farmaceutica liquida stabile a base di trazodone |
| WO2009036368A2 (en) | 2007-09-14 | 2009-03-19 | Nitto Denko Corporation | Drug carriers |
| US9295677B2 (en) | 2008-02-26 | 2016-03-29 | Qing Bile Therapeutics Inc. | Polyhydroxylated bile acids for treatment of biliary disorders |
| US20100021538A1 (en) * | 2008-02-29 | 2010-01-28 | Youngro Byun | Pharmaceutical compositions containing heparin derivatives |
| US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
| JP5420946B2 (ja) * | 2009-03-23 | 2014-02-19 | 富士フイルム株式会社 | 胆汁酸を含むミノキシジル水性組成物 |
| SG178562A1 (en) * | 2009-08-25 | 2012-03-29 | Victor Ling | Polyhydroxylated bile acids for treatment of biliary disorders |
| WO2012112940A1 (en) | 2011-02-18 | 2012-08-23 | Kythera Biopharmaceuticals, Inc. | Treatment of submental fat |
| US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
| MY184277A (en) * | 2011-08-23 | 2021-03-30 | Kythera Biopharmaceuticals Inc | Formulations of deoxyccholic acid and salts thereof |
| CN104039327B (zh) | 2012-01-06 | 2017-02-15 | 大熊制药株式会社 | 含有牛磺熊去氧胆酸的组合物 |
| WO2014152196A1 (en) | 2013-03-15 | 2014-09-25 | Janssen Pharmaceutica Nv | Pharmaceutical composition of s-ketamine hydrochloride |
| US9884066B2 (en) | 2013-06-06 | 2018-02-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Bile acid-basic amino acid conjugates and uses thereof |
| WO2015089105A1 (en) | 2013-12-09 | 2015-06-18 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
| WO2016025581A1 (en) | 2014-08-13 | 2016-02-18 | Janssen Pharmaceutica Nv | Method for the treatment of depression |
| AU2015318123A1 (en) | 2014-09-15 | 2017-03-30 | Janssen Pharmaceutica Nv | Val66Met (SNP rs6265) genotype specific dosing regimens and methods for the treatment of depression |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
| KR20180036580A (ko) * | 2016-09-30 | 2018-04-09 | 주식회사 유스바이오팜 | 수가용화(水加溶化)된 우르소데옥시콜산을 함유하는 염증성 피부질환 또는 중증 소양증 예방 또는 치료용 조성물 |
| WO2018062922A1 (ko) * | 2016-09-30 | 2018-04-05 | 주식회사 유스바이오팜 | 수가용화된 우르소데옥시콜산을 함유하는 염증성 피부질환 또는 중증 소양증 예방 또는 치료용 조성물 |
| KR102252450B1 (ko) * | 2017-02-09 | 2021-05-14 | 주식회사 아미코젠파마 | 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물 |
| WO2018147685A1 (ko) * | 2017-02-09 | 2018-08-16 | 주식회사 유스바이오팜 | 우르소데옥시콜산을 함유하는 시각장애 예방 또는 치료용 조성물 |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| CA3086478A1 (en) | 2017-12-22 | 2019-06-27 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
| JP2019127471A (ja) * | 2018-01-26 | 2019-08-01 | 株式会社ヤマザキ | 美肌用組成物 |
| IL318198A (en) | 2019-03-05 | 2025-03-01 | Janssen Pharmaceuticals Inc | Esketamine for the treatment of depression |
| CN119300836A (zh) * | 2022-03-31 | 2025-01-10 | Nzp英国有限公司 | 用于治疗肠道菌群失调并用作益生素的7-酮石胆酸 |
Citations (3)
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|---|---|---|---|---|
| JPS62153220A (ja) * | 1985-12-27 | 1987-07-08 | Tokyo Tanabe Co Ltd | 胆汁酸内用水剤 |
| US5534505A (en) * | 1993-08-30 | 1996-07-09 | Medichemie Ag | Ursodeoxycholic acid-containing medicament in a liquid adminstration form |
| US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
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| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| JPS5522616A (en) | 1978-08-04 | 1980-02-18 | Tokyo Tanabe Co Ltd | Bile acid inclusion compound and injection containing the same |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| GB8417895D0 (en) | 1984-07-13 | 1984-08-15 | Marples B A | Pharmaceutical anti-fungal composition |
| HU203204B (en) | 1987-09-15 | 1991-06-28 | Sandoz Ag | Process for producing suppository containing calcitonin and taurocholic acid |
| JP2851627B2 (ja) * | 1987-10-15 | 1999-01-27 | シンテックス(ユー・エス・エイ)インコーポレイテッド | 粉末形態ポリプペチド類の経鼻投与 |
| HU206367B (en) * | 1988-04-30 | 1992-10-28 | Sandoz Ag | Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts |
| DK0527153T3 (da) * | 1990-04-04 | 1996-11-25 | Berwind Pharma Service | Vandige filmovertræk af maltodextrin og cellulosepolymerer |
| US5057321A (en) | 1990-06-13 | 1991-10-15 | Alza Corporation | Dosage form comprising drug and maltodextrin |
| JPH0749438B2 (ja) * | 1990-10-31 | 1995-05-31 | 東京田辺製薬株式会社 | タウリン抱合型胆汁酸の精製方法 |
| IT1245890B (it) | 1991-04-12 | 1994-10-25 | Alfa Wassermann Spa | Formulazioni farmaceutiche per uso orale gastroresistenti contenenti acidi biliari. |
| IT1245891B (it) | 1991-04-12 | 1994-10-25 | Alfa Wassermann Spa | Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali. |
| IT1245889B (it) | 1991-04-12 | 1994-10-25 | Alfa Wassermann Spa | Formulazioni farmaceutiche per uso orale gastroresistenti contenenti sali di acidi biliari. |
| CH680704A5 (enExample) | 1991-05-15 | 1992-10-30 | Medichemie Ag | |
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| US5260074A (en) | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
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| CA2159219A1 (en) | 1993-03-31 | 1994-10-13 | Minoru Maeda | Cholestasis ameliorant |
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| DE4432708A1 (de) | 1994-09-14 | 1996-03-21 | Hoechst Ag | Modifizierte Gallensäuren, Verfahren zu ihrer Herstellung und ihre Verwendung |
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| US5763435A (en) * | 1995-11-21 | 1998-06-09 | Children's Hospital Medical Center | Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders |
| US5843929A (en) | 1996-03-22 | 1998-12-01 | Mayo Foundation For Medical Education And Research | Chemoprevention of metachronous adenomatous colorectal polyps |
| EP0906106B1 (en) * | 1996-05-23 | 2008-05-07 | Novartis AG | Prevention and treatment of colonic adenoma or colonic microadenoma by 6-fluoroursodeoxycholic acid (6-fudca) |
| DE29717252U1 (de) | 1997-09-26 | 1998-02-19 | Dr. Falk Pharma GmbH, 79108 Freiburg | Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen |
-
1999
- 1999-07-20 AU AU50819/99A patent/AU758679B2/en not_active Ceased
- 1999-07-20 JP JP2000560868A patent/JP4790123B2/ja not_active Expired - Fee Related
- 1999-07-20 RU RU2001105906/15A patent/RU2224523C2/ru not_active IP Right Cessation
- 1999-07-20 US US09/357,549 patent/US6251428B1/en not_active Expired - Fee Related
- 1999-07-20 EP EP99935313A patent/EP1113785B1/en not_active Expired - Lifetime
- 1999-07-20 KR KR10-2001-7001037A patent/KR100524358B1/ko not_active Expired - Lifetime
- 1999-07-20 ID IDW20010199D patent/ID29632A/id unknown
- 1999-07-20 WO PCT/US1999/012840 patent/WO2000004875A2/en not_active Ceased
- 1999-07-20 PT PT99935313T patent/PT1113785E/pt unknown
- 1999-07-20 AT AT99935313T patent/ATE292956T1/de active
- 1999-07-20 ES ES99935313T patent/ES2238843T3/es not_active Expired - Lifetime
- 1999-07-20 IL IL14098699A patent/IL140986A0/xx active IP Right Grant
- 1999-07-20 DE DE69924740T patent/DE69924740T2/de not_active Expired - Lifetime
- 1999-07-20 CN CNB998101478A patent/CN1205922C/zh not_active Expired - Fee Related
- 1999-07-20 BR BR9912395-9A patent/BR9912395A/pt not_active Application Discontinuation
- 1999-07-20 CA CA002338457A patent/CA2338457C/en not_active Expired - Fee Related
-
2001
- 2001-01-18 IL IL140986A patent/IL140986A/en not_active IP Right Cessation
-
2010
- 2010-10-18 JP JP2010233252A patent/JP2011021031A/ja not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62153220A (ja) * | 1985-12-27 | 1987-07-08 | Tokyo Tanabe Co Ltd | 胆汁酸内用水剤 |
| US5534505A (en) * | 1993-08-30 | 1996-07-09 | Medichemie Ag | Ursodeoxycholic acid-containing medicament in a liquid adminstration form |
| US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000004875A2 (en) | 2000-02-03 |
| JP2002522357A (ja) | 2002-07-23 |
| AU758679B2 (en) | 2003-03-27 |
| RU2224523C2 (ru) | 2004-02-27 |
| CA2338457A1 (en) | 2000-02-03 |
| ATE292956T1 (de) | 2005-04-15 |
| CN1348360A (zh) | 2002-05-08 |
| DE69924740T2 (de) | 2005-09-01 |
| AU5081999A (en) | 2000-02-14 |
| PT1113785E (pt) | 2005-08-31 |
| EP1113785B1 (en) | 2005-04-13 |
| JP4790123B2 (ja) | 2011-10-12 |
| ES2238843T3 (es) | 2005-09-01 |
| BR9912395A (pt) | 2001-10-16 |
| EP1113785A2 (en) | 2001-07-11 |
| US6251428B1 (en) | 2001-06-26 |
| CN1205922C (zh) | 2005-06-15 |
| WO2000004875A3 (en) | 2001-05-03 |
| CA2338457C (en) | 2009-11-17 |
| JP2011021031A (ja) | 2011-02-03 |
| IL140986A (en) | 2006-08-01 |
| IL140986A0 (en) | 2002-02-10 |
| ID29632A (id) | 2001-09-06 |
| DE69924740D1 (de) | 2005-05-19 |
| KR20010074748A (ko) | 2001-08-09 |
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