KR100453394B1 - 브라디키닌길항제를포함하는만성섬유화간질환및급성간질환치료용약제학적조성물 - Google Patents

브라디키닌길항제를포함하는만성섬유화간질환및급성간질환치료용약제학적조성물 Download PDF

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Publication number
KR100453394B1
KR100453394B1 KR1019970010677A KR19970010677A KR100453394B1 KR 100453394 B1 KR100453394 B1 KR 100453394B1 KR 1019970010677 A KR1019970010677 A KR 1019970010677A KR 19970010677 A KR19970010677 A KR 19970010677A KR 100453394 B1 KR100453394 B1 KR 100453394B1
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KR1019970010677A
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Korean (ko)
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KR970064622A (ko
Inventor
게르하르트 브라이폴
슈테판 헨케
요헨 크놀레
클라우스 비르트
막스 흐로포트
마르틴 빅켈
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훽스트 악티엔게젤샤프트
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019970010677A 1996-03-27 1997-03-27 브라디키닌길항제를포함하는만성섬유화간질환및급성간질환치료용약제학적조성물 Expired - Fee Related KR100453394B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19612067.5 1996-03-27
DE19612067A DE19612067A1 (de) 1996-03-27 1996-03-27 Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen

Publications (2)

Publication Number Publication Date
KR970064622A KR970064622A (ko) 1997-10-13
KR100453394B1 true KR100453394B1 (ko) 2004-12-30

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ID=7789557

Family Applications (1)

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KR1019970010677A Expired - Fee Related KR100453394B1 (ko) 1996-03-27 1997-03-27 브라디키닌길항제를포함하는만성섬유화간질환및급성간질환치료용약제학적조성물

Country Status (24)

Country Link
US (1) US5863901A (enExample)
EP (1) EP0797997B1 (enExample)
JP (1) JP4185169B2 (enExample)
KR (1) KR100453394B1 (enExample)
CN (1) CN1164421A (enExample)
AT (1) ATE297749T1 (enExample)
AU (1) AU1651697A (enExample)
BR (1) BR9701455A (enExample)
CA (1) CA2200040A1 (enExample)
CZ (1) CZ90797A3 (enExample)
DE (2) DE19612067A1 (enExample)
DK (1) DK0797997T3 (enExample)
ES (1) ES2242973T3 (enExample)
HR (1) HRP970171A2 (enExample)
HU (1) HUP9700642A3 (enExample)
ID (1) ID16413A (enExample)
IL (1) IL120521A0 (enExample)
NO (1) NO971453L (enExample)
PL (1) PL319193A1 (enExample)
PT (1) PT797997E (enExample)
SI (1) SI0797997T1 (enExample)
SK (1) SK39297A3 (enExample)
TR (1) TR199700228A2 (enExample)
ZA (1) ZA972599B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914236A1 (en) 2002-04-10 2008-04-23 Ortho-McNeil Pharmaceutical, Inc. Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators
TWI407960B (zh) 2007-03-23 2013-09-11 Jerini Ag 小分子緩激肽ｂ２受體調節劑
EP2318003A1 (en) * 2008-06-20 2011-05-11 Kinemed, Inc. Compositions for the treatment of fibrotic diseases or conditions
ES2908409T3 (es) 2017-11-24 2022-04-29 Pharvaris Netherlands B V Antagonistas novedosos del receptor B2 de bradiquinina
AR118983A1 (es) 2019-05-23 2021-11-17 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina
UY38706A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02184697A (ja) * 1988-11-24 1990-07-19 Hoechst Ag ブラジキニンアンタゴニスト作用を有するペプチド
KR910018405A (ko) * 1990-04-26 1991-11-30 펜스케, 라피체 브라디키닌-길항 작용이 있는 펩티드
JPH07206703A (ja) * 1993-12-31 1995-08-08 Hoechst Ag ウイルス疾患の治療用の医薬を製造するためのブラジキニン拮抗薬の使用
WO1995024422A1 (en) * 1994-03-09 1995-09-14 Cortech, Inc. Bradykinin antagonist peptides incorporating n-substituted glycines

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
WO1989009230A1 (en) * 1988-03-25 1989-10-05 Administrators Of The Tulane Educational Fund Therapeutic peptides
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
EP0502987B1 (en) * 1989-12-08 1994-08-31 Trustees Of Boston University Acylated bradykinin antagonists and uses therefor
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
FI934300A7 (fi) * 1991-04-01 1993-10-20 Cortech Inc Bradykiniiniantagonisteja
ATE169823T1 (de) * 1991-04-19 1998-09-15 Scios Nova Inc Bradykinin typische peptide
CA2106762C (en) * 1991-04-19 2000-10-10 Donald J. Kyle Bradykinin antagonist peptides
WO1993011789A1 (en) * 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
FR2686343B1 (fr) * 1992-01-17 1994-03-11 Adir Cie Nouveaux derives pseudopeptidiques a activite antagoniste de la bradykinine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW258739B (enExample) * 1992-04-04 1995-10-01 Hoechst Ag
FR2692581B1 (fr) * 1992-06-18 1994-08-19 Adir Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO1994006453A1 (en) * 1992-09-11 1994-03-31 Stewart John M Bradykinin antagonists containing aliphatic amino acids in the 5-position
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
IL107400A0 (en) * 1992-11-10 1994-01-25 Cortech Inc Bradykinin antagonists
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
AU680870B2 (en) * 1993-04-28 1997-08-14 Astellas Pharma Inc. New heterocyclic compounds
ATE191486T1 (de) * 1993-09-09 2000-04-15 Scios Inc Pseudo-oder nicht peptidartige bradykinin rezeptor antagoniste

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02184697A (ja) * 1988-11-24 1990-07-19 Hoechst Ag ブラジキニンアンタゴニスト作用を有するペプチド
KR910018405A (ko) * 1990-04-26 1991-11-30 펜스케, 라피체 브라디키닌-길항 작용이 있는 펩티드
JPH07206703A (ja) * 1993-12-31 1995-08-08 Hoechst Ag ウイルス疾患の治療用の医薬を製造するためのブラジキニン拮抗薬の使用
WO1995024422A1 (en) * 1994-03-09 1995-09-14 Cortech, Inc. Bradykinin antagonist peptides incorporating n-substituted glycines

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Naunyn Schmiedebergs Arch Pharmacol, Vol352/No5, 1995년, P557-64 *

Also Published As

Publication number Publication date
SK39297A3 (en) 1997-10-08
HU9700642D0 (en) 1997-05-28
ATE297749T1 (de) 2005-07-15
AU1651697A (en) 1997-10-02
HUP9700642A3 (en) 1998-03-02
KR970064622A (ko) 1997-10-13
EP0797997B1 (de) 2005-06-15
CZ90797A3 (en) 1997-10-15
ES2242973T3 (es) 2005-11-16
JP4185169B2 (ja) 2008-11-26
TR199700228A2 (xx) 1997-10-21
DE19612067A1 (de) 1997-10-02
HRP970171A2 (en) 1998-04-30
IL120521A0 (en) 1997-07-13
EP0797997A3 (de) 2000-05-31
CA2200040A1 (en) 1997-09-27
ID16413A (id) 1997-09-25
DE59712344D1 (de) 2005-07-21
HUP9700642A2 (hu) 1998-01-28
NO971453D0 (no) 1997-03-26
PT797997E (pt) 2005-09-30
JPH1017491A (ja) 1998-01-20
CN1164421A (zh) 1997-11-12
BR9701455A (pt) 1998-08-18
US5863901A (en) 1999-01-26
SI0797997T1 (en) 2005-10-31
MX9702292A (es) 1997-09-30
PL319193A1 (en) 1997-09-29
NO971453L (no) 1997-09-29
ZA972599B (en) 1997-09-29
DK0797997T3 (da) 2005-10-17
EP0797997A2 (de) 1997-10-01

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