HRP970171A2 - Use of bradykinin antagonists for the preparation of medicaments to treat chronic fibrogenetic liver disease and acute liver disease - Google Patents

Use of bradykinin antagonists for the preparation of medicaments to treat chronic fibrogenetic liver disease and acute liver disease

Info

Publication number
HRP970171A2
HRP970171A2 HR19612067.5A HRP970171A HRP970171A2 HR P970171 A2 HRP970171 A2 HR P970171A2 HR P970171 A HRP970171 A HR P970171A HR P970171 A2 HRP970171 A2 HR P970171A2
Authority
HR
Croatia
Prior art keywords
liver disease
preparation
medicaments
treat chronic
bradykinin antagonists
Prior art date
Application number
HR19612067.5A
Other languages
English (en)
Inventor
Gerhard Breipohl
Stephan Henke
Jochen Knolle
Klaus Wirth
Max Hropot
Udo Albus
Martin Bickel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP970171A2 publication Critical patent/HRP970171A2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR19612067.5A 1996-03-27 1997-03-26 Use of bradykinin antagonists for the preparation of medicaments to treat chronic fibrogenetic liver disease and acute liver disease HRP970171A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19612067A DE19612067A1 (de) 1996-03-27 1996-03-27 Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen

Publications (1)

Publication Number Publication Date
HRP970171A2 true HRP970171A2 (en) 1998-04-30

Family

ID=7789557

Family Applications (1)

Application Number Title Priority Date Filing Date
HR19612067.5A HRP970171A2 (en) 1996-03-27 1997-03-26 Use of bradykinin antagonists for the preparation of medicaments to treat chronic fibrogenetic liver disease and acute liver disease

Country Status (24)

Country Link
US (1) US5863901A (xx)
EP (1) EP0797997B1 (xx)
JP (1) JP4185169B2 (xx)
KR (1) KR100453394B1 (xx)
CN (1) CN1164421A (xx)
AT (1) ATE297749T1 (xx)
AU (1) AU1651697A (xx)
BR (1) BR9701455A (xx)
CA (1) CA2200040A1 (xx)
CZ (1) CZ90797A3 (xx)
DE (2) DE19612067A1 (xx)
DK (1) DK0797997T3 (xx)
ES (1) ES2242973T3 (xx)
HR (1) HRP970171A2 (xx)
HU (1) HUP9700642A3 (xx)
ID (1) ID16413A (xx)
IL (1) IL120521A0 (xx)
NO (1) NO971453L (xx)
PL (1) PL319193A1 (xx)
PT (1) PT797997E (xx)
SI (1) SI0797997T1 (xx)
SK (1) SK39297A3 (xx)
TR (1) TR199700228A2 (xx)
ZA (1) ZA972599B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914236A1 (en) 2002-04-10 2008-04-23 Ortho-McNeil Pharmaceutical, Inc. Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators
TWI407960B (zh) 2007-03-23 2013-09-11 Jerini Ag 小分子緩激肽ｂ２受體調節劑
CA2728766A1 (en) * 2008-06-20 2009-12-23 Kinemed, Inc. Compositions for the treatment of fibrotic diseases or conditions
TWI768156B (zh) 2017-11-24 2022-06-21 荷蘭商帕法瑞斯荷蘭有限公司 新穎緩激肽ｂ２受體拮抗劑及其用途
UY38706A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina
UY38707A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Nuevos antagonistas cíclicos del receptor b2 de bradiquinina

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
AU3428089A (en) * 1988-03-25 1989-10-16 The Administrators Of The Tulane Eductional Fund Therapeutic peptides
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE69012142D1 (de) * 1989-12-08 1994-10-06 Univ Boston Acylierte bradykininantagonisten und deren verwendung.
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
EP0586613A4 (en) * 1991-04-01 1994-08-24 Cortech Inc Bradykinin antagonists
ATE169823T1 (de) * 1991-04-19 1998-09-15 Scios Nova Inc Bradykinin typische peptide
CA2106762C (en) * 1991-04-19 2000-10-10 Donald J. Kyle Bradykinin antagonist peptides
WO1993011789A1 (en) * 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
FR2686343B1 (fr) * 1992-01-17 1994-03-11 Adir Cie Nouveaux derives pseudopeptidiques a activite antagoniste de la bradykinine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW258739B (xx) * 1992-04-04 1995-10-01 Hoechst Ag
FR2692581B1 (fr) * 1992-06-18 1994-08-19 Adir Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO1994006453A1 (en) * 1992-09-11 1994-03-31 Stewart John M Bradykinin antagonists containing aliphatic amino acids in the 5-position
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
IL107400A0 (en) * 1992-11-10 1994-01-25 Cortech Inc Bradykinin antagonists
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
AU680870B2 (en) * 1993-04-28 1997-08-14 Astellas Pharma Inc. New heterocyclic compounds
ES2148347T3 (es) * 1993-09-09 2000-10-16 Scios Inc Antagonistas del receptor de la bradiquinina pseudo y no peptidica.
DE4345062A1 (de) * 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
DE69533704D1 (de) * 1994-03-09 2004-12-02 Cortech Inc Bradykinin-antagonist peptide mit n-substituierten glycinen

Also Published As

Publication number Publication date
JP4185169B2 (ja) 2008-11-26
NO971453D0 (no) 1997-03-26
HU9700642D0 (en) 1997-05-28
KR970064622A (ko) 1997-10-13
IL120521A0 (en) 1997-07-13
ES2242973T3 (es) 2005-11-16
NO971453L (no) 1997-09-29
HUP9700642A3 (en) 1998-03-02
CA2200040A1 (en) 1997-09-27
EP0797997A3 (de) 2000-05-31
ZA972599B (en) 1997-09-29
DE19612067A1 (de) 1997-10-02
BR9701455A (pt) 1998-08-18
CZ90797A3 (en) 1997-10-15
ATE297749T1 (de) 2005-07-15
DE59712344D1 (de) 2005-07-21
TR199700228A2 (xx) 1997-10-21
SI0797997T1 (en) 2005-10-31
CN1164421A (zh) 1997-11-12
KR100453394B1 (ko) 2004-12-30
US5863901A (en) 1999-01-26
DK0797997T3 (da) 2005-10-17
ID16413A (id) 1997-09-25
SK39297A3 (en) 1997-10-08
PT797997E (pt) 2005-09-30
HUP9700642A2 (hu) 1998-01-28
AU1651697A (en) 1997-10-02
MX9702292A (es) 1997-09-30
EP0797997A2 (de) 1997-10-01
EP0797997B1 (de) 2005-06-15
JPH1017491A (ja) 1998-01-20
PL319193A1 (en) 1997-09-29

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Legal Events

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A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
OBST Application withdrawn