KE3501A - Dibenzocycloheptenimines - Google Patents

Dibenzocycloheptenimines

Info

Publication number
KE3501A
KE3501A KE3501A KE350185A KE3501A KE 3501 A KE3501 A KE 3501A KE 3501 A KE3501 A KE 3501A KE 350185 A KE350185 A KE 350185A KE 3501 A KE3501 A KE 3501A
Authority
KE
Kenya
Prior art keywords
dibenzocycloheptenimines
Prior art date
Application number
KE3501A
Other languages
English (en)
Inventor
Stanley Anderson Paul
Elisabeth Christy Marcia
Edward Evans Ben
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of KE3501A publication Critical patent/KE3501A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C07D295/116—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KE3501A 1977-09-19 1985-02-05 Dibenzocycloheptenimines KE3501A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83463977A 1977-09-19 1977-09-19

Publications (1)

Publication Number Publication Date
KE3501A true KE3501A (en) 1985-02-22

Family

ID=25267426

Family Applications (1)

Application Number Title Priority Date Filing Date
KE3501A KE3501A (en) 1977-09-19 1985-02-05 Dibenzocycloheptenimines

Country Status (33)

Country Link
JP (1) JPS5463100A (sv)
AR (1) AR231544A1 (sv)
AT (1) AT370103B (sv)
AU (1) AU520178B2 (sv)
BE (1) BE870562A (sv)
CA (1) CA1129850A (sv)
CH (1) CH637954A5 (sv)
CY (1) CY1283A (sv)
DE (1) DE2840786A1 (sv)
DK (1) DK153843C (sv)
ES (7) ES473492A1 (sv)
FI (1) FI65618C (sv)
FR (1) FR2403334A1 (sv)
GB (2) GB2061947B (sv)
GR (1) GR65703B (sv)
HK (1) HK30885A (sv)
HU (1) HU180868B (sv)
IE (1) IE47355B1 (sv)
IL (1) IL55521A0 (sv)
IT (1) IT1113279B (sv)
KE (1) KE3501A (sv)
LU (1) LU80262A1 (sv)
NL (1) NL191488C (sv)
NO (1) NO151861C (sv)
NZ (1) NZ188361A (sv)
PH (1) PH15920A (sv)
PL (3) PL121605B1 (sv)
PT (1) PT68544A (sv)
SE (1) SE437520B (sv)
SG (1) SG9585G (sv)
SU (2) SU895288A3 (sv)
YU (1) YU41432B (sv)
ZA (1) ZA785291B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232158A (en) * 1979-06-04 1980-11-04 Merck & Co., Inc. 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines
US4477668A (en) * 1982-04-07 1984-10-16 Merck & Co., Inc. Process for 5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine
GB8719199D0 (en) * 1987-08-13 1987-09-23 Merck Sharp & Dohme Chemical compounds
US5686614A (en) * 1995-04-11 1997-11-11 Neurogen Corporation Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution
US5739337A (en) * 1996-03-08 1998-04-14 Neurogen Corporation Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo 3.2.1!octanes
WO2017093354A1 (en) 2015-11-30 2017-06-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Nmdar antagonists for the treatment of diseases associated with angiogenesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794904A (fr) * 1972-02-04 1973-08-02 Roussel Uclaf Nouveaux derives du dibenzocycloheptene et leur preparation
BE829075A (fr) * 1974-05-15 1975-11-14 9,10-dihydroanthracen-9,10-imines substituees et leurs analogues heterocycliques (aza)

Also Published As

Publication number Publication date
NZ188361A (en) 1982-06-29
GB2004872B (en) 1982-04-15
AU520178B2 (en) 1982-01-21
FI782680A (fi) 1979-03-20
NO151861B (no) 1985-03-11
DK153843B (da) 1988-09-12
PL118478B1 (en) 1981-10-31
SU915800A3 (en) 1982-03-23
HU180868B (en) 1983-04-29
ES483283A1 (es) 1980-04-16
IE47355B1 (en) 1984-02-22
PL121605B1 (en) 1982-05-31
GR65703B (en) 1980-10-22
IE781866L (en) 1979-03-19
NL191488C (nl) 1995-08-04
PL112834B1 (en) 1980-11-29
NO783017L (no) 1979-03-20
FI65618C (fi) 1984-06-11
NL191488B (nl) 1995-04-03
SU895288A3 (ru) 1981-12-30
NO151861C (no) 1985-06-19
CH637954A5 (de) 1983-08-31
GB2061947A (en) 1981-05-20
DK389978A (da) 1979-03-20
SG9585G (en) 1985-08-08
YU219678A (en) 1983-02-28
JPS5639315B2 (sv) 1981-09-11
DE2840786A1 (de) 1979-03-22
ES483286A1 (es) 1980-04-16
YU41432B (en) 1987-06-30
IT1113279B (it) 1986-01-20
SE7809187L (sv) 1979-03-20
DE2840786C2 (sv) 1987-05-21
CY1283A (en) 1985-07-05
ES483285A1 (es) 1980-09-01
FR2403334A1 (fr) 1979-04-13
SE437520B (sv) 1985-03-04
ES473492A1 (es) 1980-07-16
ZA785291B (en) 1980-04-30
AR231544A1 (es) 1984-12-28
PL209632A1 (pl) 1979-06-04
IT7851126A0 (it) 1978-09-18
NL7808847A (nl) 1979-03-21
CA1129850A (en) 1982-08-17
LU80262A1 (fr) 1979-06-01
FR2403334B1 (sv) 1982-11-19
JPS5463100A (en) 1979-05-21
AU3966878A (en) 1980-03-13
PH15920A (en) 1983-04-22
AT370103B (de) 1983-03-10
GB2061947B (en) 1982-08-04
ATA669778A (de) 1982-07-15
ES483288A1 (es) 1980-04-16
DK153843C (da) 1989-01-23
ES483284A1 (es) 1980-09-01
GB2004872A (en) 1979-04-11
HK30885A (en) 1985-04-26
BE870562A (fr) 1979-03-19
PT68544A (en) 1978-10-01
ES483287A1 (es) 1980-04-16
FI65618B (fi) 1984-02-29
IL55521A0 (en) 1978-12-17

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