JPS5639315B2 - - Google Patents

Info

Publication number
JPS5639315B2
JPS5639315B2 JP11420078A JP11420078A JPS5639315B2 JP S5639315 B2 JPS5639315 B2 JP S5639315B2 JP 11420078 A JP11420078 A JP 11420078A JP 11420078 A JP11420078 A JP 11420078A JP S5639315 B2 JPS5639315 B2 JP S5639315B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP11420078A
Other languages
Japanese (ja)
Other versions
JPS5463100A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5463100A publication Critical patent/JPS5463100A/ja
Publication of JPS5639315B2 publication Critical patent/JPS5639315B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C07D295/116Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings with the doubly bound oxygen or sulfur atoms directly attached to a carbocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP11420078A 1977-09-19 1978-09-19 55substitutedd10*111dihydroo5hhdibenzoo*a*d** cycloheptenee5*100imine Granted JPS5463100A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83463977A 1977-09-19 1977-09-19

Publications (2)

Publication Number Publication Date
JPS5463100A JPS5463100A (en) 1979-05-21
JPS5639315B2 true JPS5639315B2 (sv) 1981-09-11

Family

ID=25267426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11420078A Granted JPS5463100A (en) 1977-09-19 1978-09-19 55substitutedd10*111dihydroo5hhdibenzoo*a*d** cycloheptenee5*100imine

Country Status (33)

Country Link
JP (1) JPS5463100A (sv)
AR (1) AR231544A1 (sv)
AT (1) AT370103B (sv)
AU (1) AU520178B2 (sv)
BE (1) BE870562A (sv)
CA (1) CA1129850A (sv)
CH (1) CH637954A5 (sv)
CY (1) CY1283A (sv)
DE (1) DE2840786A1 (sv)
DK (1) DK153843C (sv)
ES (7) ES473492A1 (sv)
FI (1) FI65618C (sv)
FR (1) FR2403334A1 (sv)
GB (2) GB2061947B (sv)
GR (1) GR65703B (sv)
HK (1) HK30885A (sv)
HU (1) HU180868B (sv)
IE (1) IE47355B1 (sv)
IL (1) IL55521A0 (sv)
IT (1) IT1113279B (sv)
KE (1) KE3501A (sv)
LU (1) LU80262A1 (sv)
NL (1) NL191488C (sv)
NO (1) NO151861C (sv)
NZ (1) NZ188361A (sv)
PH (1) PH15920A (sv)
PL (3) PL121605B1 (sv)
PT (1) PT68544A (sv)
SE (1) SE437520B (sv)
SG (1) SG9585G (sv)
SU (2) SU895288A3 (sv)
YU (1) YU41432B (sv)
ZA (1) ZA785291B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232158A (en) * 1979-06-04 1980-11-04 Merck & Co., Inc. 10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines
US4477668A (en) * 1982-04-07 1984-10-16 Merck & Co., Inc. Process for 5-methyl-10,11-dihydro-5H-dibenzo[a,d]-cyclohepten-5,10-imine
GB8719199D0 (en) * 1987-08-13 1987-09-23 Merck Sharp & Dohme Chemical compounds
US5686614A (en) * 1995-04-11 1997-11-11 Neurogen Corporation Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution
US5739337A (en) * 1996-03-08 1998-04-14 Neurogen Corporation Process for preparing dibenzo-1-carboxamido-1,4-azabicyclo 3.2.1!octanes
WO2017093354A1 (en) 2015-11-30 2017-06-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Nmdar antagonists for the treatment of diseases associated with angiogenesis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794904A (fr) * 1972-02-04 1973-08-02 Roussel Uclaf Nouveaux derives du dibenzocycloheptene et leur preparation
BE829075A (fr) * 1974-05-15 1975-11-14 9,10-dihydroanthracen-9,10-imines substituees et leurs analogues heterocycliques (aza)

Also Published As

Publication number Publication date
NZ188361A (en) 1982-06-29
GB2004872B (en) 1982-04-15
AU520178B2 (en) 1982-01-21
FI782680A (fi) 1979-03-20
NO151861B (no) 1985-03-11
DK153843B (da) 1988-09-12
PL118478B1 (en) 1981-10-31
SU915800A3 (en) 1982-03-23
HU180868B (en) 1983-04-29
ES483283A1 (es) 1980-04-16
IE47355B1 (en) 1984-02-22
PL121605B1 (en) 1982-05-31
GR65703B (en) 1980-10-22
IE781866L (en) 1979-03-19
NL191488C (nl) 1995-08-04
PL112834B1 (en) 1980-11-29
NO783017L (no) 1979-03-20
FI65618C (fi) 1984-06-11
KE3501A (en) 1985-02-22
NL191488B (nl) 1995-04-03
SU895288A3 (ru) 1981-12-30
NO151861C (no) 1985-06-19
CH637954A5 (de) 1983-08-31
GB2061947A (en) 1981-05-20
DK389978A (da) 1979-03-20
SG9585G (en) 1985-08-08
YU219678A (en) 1983-02-28
DE2840786A1 (de) 1979-03-22
ES483286A1 (es) 1980-04-16
YU41432B (en) 1987-06-30
IT1113279B (it) 1986-01-20
SE7809187L (sv) 1979-03-20
DE2840786C2 (sv) 1987-05-21
CY1283A (en) 1985-07-05
ES483285A1 (es) 1980-09-01
FR2403334A1 (fr) 1979-04-13
SE437520B (sv) 1985-03-04
ES473492A1 (es) 1980-07-16
ZA785291B (en) 1980-04-30
AR231544A1 (es) 1984-12-28
PL209632A1 (pl) 1979-06-04
IT7851126A0 (it) 1978-09-18
NL7808847A (nl) 1979-03-21
CA1129850A (en) 1982-08-17
LU80262A1 (fr) 1979-06-01
FR2403334B1 (sv) 1982-11-19
JPS5463100A (en) 1979-05-21
AU3966878A (en) 1980-03-13
PH15920A (en) 1983-04-22
AT370103B (de) 1983-03-10
GB2061947B (en) 1982-08-04
ATA669778A (de) 1982-07-15
ES483288A1 (es) 1980-04-16
DK153843C (da) 1989-01-23
ES483284A1 (es) 1980-09-01
GB2004872A (en) 1979-04-11
HK30885A (en) 1985-04-26
BE870562A (fr) 1979-03-19
PT68544A (en) 1978-10-01
ES483287A1 (es) 1980-04-16
FI65618B (fi) 1984-02-29
IL55521A0 (en) 1978-12-17

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