|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US4326525A
(en)
|
1980-10-14 |
1982-04-27 |
Alza Corporation |
Osmotic device that improves delivery properties of agent in situ
|
|
US4675189A
(en)
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
|
US4723027A
(en)
|
1982-11-22 |
1988-02-02 |
E. I. Du Pont De Nemours And Company |
Preparation of optically active alpha-hydroxynitriles
|
|
ZA837994B
(en)
|
1982-11-22 |
1984-06-27 |
Shell Oil Co |
Process for the preparation of optically-active cyanomethyl esters
|
|
JPS60100516A
(ja)
|
1983-11-04 |
1985-06-04 |
Takeda Chem Ind Ltd |
徐放型マイクロカプセルの製造法
|
|
US5364620A
(en)
|
1983-12-22 |
1994-11-15 |
Elan Corporation, Plc |
Controlled absorption diltiazem formulation for once daily administration
|
|
CA1256638A
(en)
|
1984-07-06 |
1989-06-27 |
Motoaki Tanaka |
Polymer and its production
|
|
JP2551756B2
(ja)
|
1985-05-07 |
1996-11-06 |
武田薬品工業株式会社 |
ポリオキシカルボン酸エステルおよびその製造法
|
|
US5023252A
(en)
|
1985-12-04 |
1991-06-11 |
Conrex Pharmaceutical Corporation |
Transdermal and trans-membrane delivery of drugs
|
|
US4741897A
(en)
|
1986-07-08 |
1988-05-03 |
Baxter Travenol |
Thyroxine analogs and reagents for thyroid hormone assays
|
|
US5001139A
(en)
|
1987-06-12 |
1991-03-19 |
American Cyanamid Company |
Enchancers for the transdermal flux of nivadipine
|
|
US4992445A
(en)
|
1987-06-12 |
1991-02-12 |
American Cyanamid Co. |
Transdermal delivery of pharmaceuticals
|
|
DE10199033I2
(de)
|
1992-04-22 |
2003-01-09 |
Ligand Parmaceuticals Inc |
Retinoid-x Rezeptor selektive Verbindungen
|
|
DE4320444A1
(de)
|
1993-06-21 |
1994-12-22 |
Agfa Gevaert Ag |
Farbfotografisches Aufzeichnungsmaterial
|
|
AU717743B2
(en)
|
1995-12-13 |
2000-03-30 |
Regents Of The University Of California, The |
Nuclear receptor ligands and ligand binding domains
|
|
JPH09301917A
(ja)
|
1996-05-08 |
1997-11-25 |
Koichi Shudo |
甲状腺ホルモン作用性化合物
|
|
CA2260992C
(en)
|
1996-08-20 |
2004-03-09 |
The Regents Of The University Of California |
Eye treatments using synthetic thyroid hormone compositions
|
|
US5883294A
(en)
|
1997-06-18 |
1999-03-16 |
The Regeants Of The University Of California |
Selective thyroid hormone analogs
|
|
GB9713739D0
(en)
|
1997-06-27 |
1997-09-03 |
Karobio Ab |
Thyroid receptor ligands
|
|
DE69924846T2
(de)
|
1998-06-30 |
2006-04-27 |
The Regents Of The University Of California, Oakland |
Thyroidhormon-analoga und verfahren zu ihrer herstellung
|
|
GB9828442D0
(en)
|
1998-12-24 |
1999-02-17 |
Karobio Ab |
Novel thyroid receptor ligands and method II
|
|
JP2003500483A
(ja)
|
1999-06-01 |
2003-01-07 |
ザ・ユニバーシティ・オブ・テキサス・サウスウエスタン・メディカル・センター |
ビアリール化合物
|
|
US6787652B1
(en)
|
1999-09-30 |
2004-09-07 |
Pfizer, Inc. |
6-Azauracil derivatives as thyroid receptor ligands
|
|
EP1088819B1
(en)
|
1999-09-30 |
2005-06-15 |
Pfizer Products Inc. |
6-azauracil derivatives as thyroid receptor ligands
|
|
US6436990B1
(en)
|
1999-10-27 |
2002-08-20 |
Nobex Corporation |
6-methoxy-2-naphthylacetic acid prodrugs
|
|
EP1127882A1
(en)
|
2000-01-25 |
2001-08-29 |
Pfizer Products Inc. |
Tetrazole compounds as thyroid receptor ligands
|
|
CZ20022771A3
(cs)
|
2000-02-17 |
2003-09-17 |
Bristol-Myers Squibb Company |
Ligandy thyreoidního receptoru odvozené od anilinu
|
|
ATE310733T1
(de)
|
2000-04-21 |
2005-12-15 |
Pfizer Prod Inc |
Thyroid-rezeptorliganden
|
|
DE10024939A1
(de)
|
2000-05-19 |
2001-11-29 |
Bayer Ag |
Neue Diphenylmethanderivate für Arzneimittel
|
|
US6429223B1
(en)
|
2000-06-23 |
2002-08-06 |
Medinox, Inc. |
Modified forms of pharmacologically active agents and uses therefor
|
|
EP1337524A1
(en)
|
2000-11-02 |
2003-08-27 |
AstraZeneca AB |
Substituted quinolines as antitumor agents
|
|
US6777442B2
(en)
|
2001-03-12 |
2004-08-17 |
Bayer Aktiengesellschaft |
Diphenyl derivatives
|
|
US20040267015A1
(en)
|
2001-04-05 |
2004-12-30 |
Ajita Bhat |
Peptide deformylase inhibitors
|
|
US7560433B2
(en)
|
2001-12-21 |
2009-07-14 |
Biotempt B.V. |
Treatment of multiple sclerosis (MS)
|
|
US7247748B2
(en)
|
2002-03-27 |
2007-07-24 |
Smithkline Corporation |
Amide compounds and methods of using the same
|
|
US7302347B2
(en)
|
2002-12-10 |
2007-11-27 |
The Regents Of The University Of California |
Method for creating specific, high affinity nuclear receptor pharmaceuticals
|
|
US7321065B2
(en)
|
2003-04-18 |
2008-01-22 |
The Regents Of The University Of California |
Thyronamine derivatives and analogs and methods of use thereof
|
|
US8071134B2
(en)
|
2003-09-15 |
2011-12-06 |
Ordway Research Institute, Inc. |
Thyroid hormone analogs and methods of use
|
|
CN1882327A
(zh)
|
2003-11-19 |
2006-12-20 |
症变治疗公司 |
含磷的新的拟甲状腺素药
|
|
WO2006128058A2
(en)
|
2005-05-26 |
2006-11-30 |
Metabasis Therapeutics, Inc. |
Thyromimetics for the treatment of fatty liver diseases
|
|
WO2006012015A2
(en)
|
2004-06-29 |
2006-02-02 |
Oregon Health And Science University |
Methods and compositions for nerve regeneration
|
|
JP2008513461A
(ja)
|
2004-09-15 |
2008-05-01 |
オードウェイ リサーチ インスティテュート |
血管形成を促進する甲状腺ホルモンアナログ
|
|
ES2528674T3
(es)
|
2005-02-17 |
2015-02-11 |
Astellas Pharma Inc. |
Piperidina y carboxilatos de piperacina como inhibidores de FAAH
|
|
WO2006128056A2
(en)
|
2005-05-26 |
2006-11-30 |
Metabasis Therapeutics, Inc. |
Novel phosphinic acid-containing thyromimetics
|
|
AU2006249347A1
(en)
|
2005-05-26 |
2006-11-30 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
CN101180097A
(zh)
|
2005-05-26 |
2008-05-14 |
症变治疗公司 |
新型含次膦酸的拟甲状腺素药
|
|
GB0606212D0
(en)
*
|
2006-03-28 |
2006-05-10 |
Karobio Ab |
Pharmaceutical compositions
|
|
GB0608724D0
(en)
|
2006-05-03 |
2006-06-14 |
Karobio Ab |
Novel Pharmaceutical Compositions
|
|
WO2007132475A1
(en)
|
2006-05-15 |
2007-11-22 |
Cadila Healthcare Limited |
Selective tr-beta 1 agonist
|
|
JP2010506955A
(ja)
|
2006-10-20 |
2010-03-04 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
可溶性リンホトキシンβレセプターによる脱髄障害の処置
|
|
WO2008052354A1
(en)
|
2006-11-03 |
2008-05-08 |
University Of Saskatchewan |
Method of treating demyelination diseases
|
|
CN101547898B
(zh)
|
2006-12-10 |
2014-09-24 |
于崇曦 |
β-内酰胺类抗生素的透皮给药系统
|
|
CN101657193A
(zh)
|
2007-03-09 |
2010-02-24 |
切尔西治疗公司 |
用于治疗纤维肌痛的屈昔多巴及其药物组合物
|
|
FI20075245A0
(fi)
|
2007-04-11 |
2007-04-11 |
Markku Ahotupa |
Menetelmä oksidatiivisen metabolian arvioimiseksi
|
|
CA2970273C
(en)
|
2007-07-11 |
2020-04-14 |
Medicinova, Inc. |
Treatment of progressive neurodegenerative disease with ibudilast
|
|
EP2242745A1
(de)
|
2008-02-07 |
2010-10-27 |
Sanofi-Aventis |
Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
|
|
KR20130097813A
(ko)
|
2008-04-21 |
2013-09-03 |
오토노미, 인코포레이티드 |
귀 질환 및 병태를 치료하기 위한 귀 조제물
|
|
US8475804B2
(en)
|
2009-02-20 |
2013-07-02 |
U.S. Army Medical Research And Material Command |
Compositions and methods for treatment of filovirus-mediated diseases
|
|
CA2765792C
(en)
|
2009-06-17 |
2017-03-28 |
Nanopharmaceuticals Llc |
Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof
|
|
US20120245213A1
(en)
|
2009-10-01 |
2012-09-27 |
Bedrich Mosinger |
Human type i taste receptor subunit 3 modulators and methods of using same
|
|
TW201221505A
(en)
|
2010-07-05 |
2012-06-01 |
Sanofi Sa |
Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
|
|
JP5847533B2
(ja)
|
2010-10-19 |
2016-01-27 |
田辺三菱製薬株式会社 |
新規甲状腺ホルモンβ受容体作動薬
|
|
WO2013006734A1
(en)
|
2011-07-05 |
2013-01-10 |
St. Jude Children's Research Hospital |
Substituted 4-phenoxyphenol analogs as modulators of proliferating cell nuclear antigen activity
|
|
WO2013056232A2
(en)
|
2011-10-13 |
2013-04-18 |
Case Western Reserve University |
Rxr agonists compounds and methods
|
|
WO2014078892A1
(en)
|
2012-11-21 |
2014-05-30 |
Indyk Daniel |
A device and a test assembly for testing the integrity of a low voltage electrical network
|
|
WO2014178892A1
(en)
|
2013-05-03 |
2014-11-06 |
Scanlan Thomas S |
Use of sobetirome in the treatment of x-linked adrenolenoleukodystrophy
|
|
WO2015013187A1
(en)
|
2013-07-22 |
2015-01-29 |
Metabolic Solutions Development Co., Llc |
Ppar-sparing compounds for the treatment of metabolic diseases
|
|
US10258613B2
(en)
|
2014-02-05 |
2019-04-16 |
The Board Of Regents Of The University Of Oklahoma |
Compositions for treating retinal degeneration and methods of production and use thereof
|
|
US20170114019A1
(en)
|
2014-06-04 |
2017-04-27 |
Haro Pharmaceutical Inc. |
18-20 member bi-polycyclic compounds
|
|
WO2016057322A1
(en)
|
2014-10-08 |
2016-04-14 |
Salk Institute For Biological Studies |
Ppar agonists and methods of use thereof
|
|
EP3259246B1
(en)
|
2015-02-20 |
2023-03-22 |
Oregon Health & Science University |
Derivatives of sobetirome
|
|
US10532983B2
(en)
|
2015-07-20 |
2020-01-14 |
Oregon Health & Science University |
Quinolone-3-diarylethers
|
|
US11872207B2
(en)
|
2015-12-24 |
2024-01-16 |
Mcmaster University |
Dronedarone and derivatives thereof for treating cancer
|
|
CN109475121B
(zh)
*
|
2016-05-18 |
2021-06-25 |
俄勒冈健康科学大学 |
苏比替罗衍生物
|
|
US11325886B2
(en)
|
2016-08-12 |
2022-05-10 |
Oregon Health & Science University |
Amide compounds, pharmaceutical compositions thereof, and methods of using the same
|
|
WO2018208707A1
(en)
|
2017-05-08 |
2018-11-15 |
Neurovia, Inc. |
Methods and compositions for treating demyelinating diseases
|
|
IL276592B2
(en)
|
2018-02-14 |
2023-11-01 |
Univ Oregon Health & Science |
History of Subtirum
|
|
WO2019168842A1
(en)
|
2018-03-02 |
2019-09-06 |
Oregon Health & Science University |
Amide prodrugs of small molecule nuclear receptor modulators
|
|
WO2020117962A1
(en)
*
|
2018-12-05 |
2020-06-11 |
Viking Therapeutics, Inc. |
Compositions for the treatment of fibrosis and inflammation
|
|
WO2020118564A1
(en)
|
2018-12-12 |
2020-06-18 |
Autobahn Therapeutics, Inc. |
Novel thyromimetics
|
|
EP3894383A1
(en)
|
2018-12-12 |
2021-10-20 |
Autobahn Therapeutics, Inc. |
Novel thyromimetics
|
|
US12338206B2
(en)
|
2019-02-21 |
2025-06-24 |
Nanjing Ruijie Pharma Co., Ltd. |
Compounds and their uses as thyroid hormone receptor agonists
|
|
CA3130371A1
(en)
|
2019-03-01 |
2020-09-10 |
Autobahn Therapeutics, Inc. |
Novel thyromimetics
|
|
GEP20247637B
(en)
|
2019-05-08 |
2024-06-25 |
Aligos Therapeutics Inc |
Modulators of thr-b and methods of use thereof
|
|
KR20220121239A
(ko)
|
2019-11-29 |
2022-08-31 |
아우토반 쎄라퓨틱스, 인크. |
신규한 갑상선 호르몬 모방제
|
|
EP4090652A1
(en)
|
2020-01-13 |
2022-11-23 |
Eccogene (Shanghai) Co., Ltd. |
Substituted triazinones as thyroid hormone receptor agonists
|
|
WO2021247847A1
(en)
|
2020-06-03 |
2021-12-09 |
Autobahn Therapeutics, Inc. |
Isotopic thyromimetic compounds
|
|
JP7813730B2
(ja)
|
2020-06-17 |
2026-02-13 |
オートバーン セラピューティクス，インク． |
甲状腺様作用剤
|
|
US20230242473A1
(en)
|
2020-06-17 |
2023-08-03 |
Autobahn Therapeutics, Inc. |
Thyromimetics
|
|
WO2021257851A1
(en)
|
2020-06-17 |
2021-12-23 |
Autobahn Therapeutics, Inc. |
Thyromimetics
|