JPS61145200A - ウシラクトフェリンの分離精製法 - Google Patents

ウシラクトフェリンの分離精製法

Info

Publication number
JPS61145200A
JPS61145200A JP59266401A JP26640184A JPS61145200A JP S61145200 A JPS61145200 A JP S61145200A JP 59266401 A JP59266401 A JP 59266401A JP 26640184 A JP26640184 A JP 26640184A JP S61145200 A JPS61145200 A JP S61145200A
Authority
JP
Japan
Prior art keywords
lactoferrin
bovine lactoferrin
antibody
bovine
milk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59266401A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0566397B2 (https=
Inventor
Hiroshi Kawakami
浩 川上
Yoji Niimoto
洋士 新本
Shiyunichi Dousako
俊一 堂迫
Kenkichi Ahiko
阿彦　健吉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Priority to JP59266401A priority Critical patent/JPS61145200A/ja
Priority to NZ213985A priority patent/NZ213985A/xx
Priority to AU49227/85A priority patent/AU585543B2/en
Priority to US06/808,899 priority patent/US4668771A/en
Priority to GB08530898A priority patent/GB2168982B/en
Priority to DE19853544400 priority patent/DE3544400A1/de
Priority to FR8518779A priority patent/FR2574800B1/fr
Priority to BE0/216032A priority patent/BE903886A/fr
Publication of JPS61145200A publication Critical patent/JPS61145200A/ja
Publication of JPH0566397B2 publication Critical patent/JPH0566397B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/832—Milk; colostrum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP59266401A 1984-12-19 1984-12-19 ウシラクトフェリンの分離精製法 Granted JPS61145200A (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP59266401A JPS61145200A (ja) 1984-12-19 1984-12-19 ウシラクトフェリンの分離精製法
NZ213985A NZ213985A (en) 1984-12-19 1985-10-29 Method of purifying bovine lactoferrin
AU49227/85A AU585543B2 (en) 1984-12-19 1985-10-31 Method for separating bovine lactoferrin from cow's milk and purifying same
US06/808,899 US4668771A (en) 1984-12-19 1985-12-13 Method for separating bovine lactoferrin from cow's milk and purifying same
GB08530898A GB2168982B (en) 1984-12-19 1985-12-16 Method for separating bovine lactoferrin from cow's milk and purifying same
DE19853544400 DE3544400A1 (de) 1984-12-19 1985-12-16 Verfahren zum abtrennen von bovinem lactoferrin von kuhmilch und reinigen desselben
FR8518779A FR2574800B1 (fr) 1984-12-19 1985-12-18 Procede et separation de la lactoferrine bovine du lait de vache et sa purification
BE0/216032A BE903886A (fr) 1984-12-19 1985-12-18 Procede de separation de la lactoferrine bovine du lait de vache et de sa purification.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59266401A JPS61145200A (ja) 1984-12-19 1984-12-19 ウシラクトフェリンの分離精製法

Publications (2)

Publication Number Publication Date
JPS61145200A true JPS61145200A (ja) 1986-07-02
JPH0566397B2 JPH0566397B2 (https=) 1993-09-21

Family

ID=17430416

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59266401A Granted JPS61145200A (ja) 1984-12-19 1984-12-19 ウシラクトフェリンの分離精製法

Country Status (8)

Country Link
US (1) US4668771A (https=)
JP (1) JPS61145200A (https=)
AU (1) AU585543B2 (https=)
BE (1) BE903886A (https=)
DE (1) DE3544400A1 (https=)
FR (1) FR2574800B1 (https=)
GB (1) GB2168982B (https=)
NZ (1) NZ213985A (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02138295A (ja) * 1988-07-27 1990-05-28 Snow Brand Milk Prod Co Ltd 回転型カラムを利用した液中蛋白質の回収方法
EP0385118A2 (en) 1989-02-07 1990-09-05 Snow Brand Milk Products Co., Ltd. Use of compounds containing or binding sialic acid to neutralize bacterial toxins
JPH02225419A (ja) * 1989-02-27 1990-09-07 Morinaga Milk Ind Co Ltd ビフィズス菌増殖促進組成物
US4988629A (en) * 1986-11-13 1991-01-29 Behringwerke Aktiengesellschaft Lactoferrin-containing incubation medium for solid-phase immunometric methods and its use
WO1998004922A1 (en) * 1996-07-30 1998-02-05 Shionogi & Co., Ltd. Method for preventing adsorption of lactoferrin
JP2016117750A (ja) * 2016-02-02 2016-06-30 株式会社Ｎｒｌファーマ 更年期障害改善用医薬組成物ならびに飲食物

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE61701B1 (en) * 1986-07-17 1994-11-30 Morinaga Milk Industry Co Ltd Process for producing bovine lactoferrin in high purity
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
JPH0725800B2 (ja) * 1987-04-10 1995-03-22 雪印乳業株式会社 硫酸エステル化物を用いて乳からラクトフエリンを分離、精製する方法
US5344820A (en) * 1987-05-15 1994-09-06 Snow Brand Milk Products Co., Ltd. Infection protectant
US4977137B1 (en) * 1987-06-03 1994-06-28 Baylor College Medicine Lactoferrin as a dietary ingredient promoting the growth of the gastrointestinal tract
SE458818B (sv) * 1987-11-27 1989-05-16 Svenska Mejeriernas Riksforeni Foerfarande foer utvinning av rena fraktioner av laktoperoxidas och laktoferrin ur mjoelkserum
FR2631785A1 (fr) * 1988-05-27 1989-12-01 Agronomique Inst Nat Rech Procede de fractionnement des proteines du lait humain, conduisant a la production, notamment de lactoferrine et d'(alpha)-lactalbumine, et produits obtenus
AU648022B2 (en) * 1989-03-14 1994-04-14 Bionebraska, Inc. Monoclonal antibodies for metallic cations on small molecules
US5639624A (en) * 1989-03-14 1997-06-17 Board Of Regents Of The University Of Nebraska Monoclonal antibodies specific for metallic cations and method therefor
US5972656A (en) * 1989-03-14 1999-10-26 Bionebraska, Inc. Mercury binding polypeptides and nucleotides coding therefore
US5766939A (en) * 1989-05-05 1998-06-16 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5849881A (en) * 1989-05-05 1998-12-15 Baylor College Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using cDNA sequences in various organisms
US6100054A (en) * 1989-05-05 2000-08-08 Baylor College Of Medicine Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
IL94183A (en) 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5633076A (en) * 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
US5573937A (en) * 1989-12-07 1996-11-12 Snow Brand Milk Products Co., Ltd. Serum free culture medium
US5198419A (en) * 1989-12-08 1993-03-30 Immuno Japan Inc. Formulated medicines for enhancing the efficacy of beta-lactam antibiotics in prophylaxis and treatment against infectious disease due to pathogenic bacteria
DE69017921T2 (de) * 1990-01-23 1995-10-12 Morinaga Milk Industry Co. Ltd., Tokio/Tokyo Lactoferrinhydrolysat zur Verwendung als tyrosinagehemmendes Mittel.
US6066469A (en) * 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
DK0545946T3 (da) * 1990-07-13 2005-05-23 Gropep Ltd Vækstfremmende middel
US6319522B1 (en) 1990-07-13 2001-11-20 Gropep Limited Growth-promoting agent
US7033610B2 (en) 1990-07-13 2006-04-25 Gropep Pty, Ltd. Growth-promoting agent
JPH05202098A (ja) * 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
US6096870A (en) * 1994-01-05 2000-08-01 Sepragen Corporation Sequential separation of whey
EP0744901B1 (en) * 1994-02-16 2001-12-05 Pharming Intellectual Property BV Isolation of lactoferrin from milk
US6111079A (en) * 1995-06-05 2000-08-29 Bionebraska, Inc. Lead binding polypeptides and nucleotides coding therefore
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
US20040259770A1 (en) * 2003-06-19 2004-12-23 Rush University Medical Center Method for determining leukocyte activation
WO2005041680A2 (en) * 2003-11-03 2005-05-12 Advanced Protein Systems A novel colostral fractionation process
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
WO2005085287A1 (en) 2004-03-03 2005-09-15 En-N-Tech, Inc. Treatments for contaminant reduction in lactoferrin preparations and lactoferrin-containing compositions
AU2006233196B2 (en) * 2005-10-28 2012-07-05 Fonterra Co-Operative Group Limited Enriched milk products
US20070212367A1 (en) * 2006-03-13 2007-09-13 Keech Andrew M Novel immunologically active peptide fragments of a proline-rich polypeptide isolated from colostral mammalian fluids for treatment of viral and non-viral diseases or diseased conditions
US20080003329A1 (en) * 2006-06-30 2008-01-03 Ricardo Rueda Enriched infant formulas
CA2696145C (en) 2007-07-10 2016-12-20 Glanbia Nutritionals Method for removing endotoxin from proteins
US9458225B2 (en) * 2013-06-26 2016-10-04 United Arab Emirates University Method for purifying lactoferrin
CN106140099B (zh) * 2015-04-17 2018-10-16 北京美正生物科技有限公司 一种分离纯化乳铁蛋白的免疫亲和柱及其制备方法和用途
US11470858B2 (en) * 2018-03-12 2022-10-18 Morinaga Milk Industry Co., Ltd. Method for producing lactoferrin-containing aqueous solution
WO2020176637A1 (en) 2019-02-26 2020-09-03 Pantheryx, Inc. Compositions for management of disorders of the gastrointestinal tract
CN113311155B (zh) * 2021-04-09 2022-11-29 深圳市计量质量检测研究院（国家高新技术计量站、国家数字电子产品质量监督检验中心） 一种牛乳蛋白和水牛乳蛋白二联检测卡的制备方法及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59148725A (ja) * 1983-02-14 1984-08-25 Snow Brand Milk Prod Co Ltd 高純度のヒト・トランスフエリンの製法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229342A (en) * 1977-05-18 1980-10-21 Rhone-Poulenc Industries Process for extracting proteins from milk using silica and anion exchange resins
GB2091739B (en) * 1981-01-27 1984-08-01 Pulblic Helth Lab Service Boar Purification of human growth hormone
FR2505615A1 (fr) * 1981-05-15 1982-11-19 Elf Aquitaine Procede d'extraction de lactoferrine et d'immunoglobulines du lait
JPH0686480B2 (ja) * 1983-02-21 1994-11-02 雪印乳業株式会社 エリスロポエチン製造用モノクローナル抗体
JPH0669370B2 (ja) * 1984-07-13 1994-09-07 雪印乳業株式会社 モノクローナル抗ウシラクトフェリン抗体産生ハイブリドーマの製造法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59148725A (ja) * 1983-02-14 1984-08-25 Snow Brand Milk Prod Co Ltd 高純度のヒト・トランスフエリンの製法

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988629A (en) * 1986-11-13 1991-01-29 Behringwerke Aktiengesellschaft Lactoferrin-containing incubation medium for solid-phase immunometric methods and its use
JPH02138295A (ja) * 1988-07-27 1990-05-28 Snow Brand Milk Prod Co Ltd 回転型カラムを利用した液中蛋白質の回収方法
EP0385118A2 (en) 1989-02-07 1990-09-05 Snow Brand Milk Products Co., Ltd. Use of compounds containing or binding sialic acid to neutralize bacterial toxins
JPH02225419A (ja) * 1989-02-27 1990-09-07 Morinaga Milk Ind Co Ltd ビフィズス菌増殖促進組成物
WO1998004922A1 (en) * 1996-07-30 1998-02-05 Shionogi & Co., Ltd. Method for preventing adsorption of lactoferrin
JP2016117750A (ja) * 2016-02-02 2016-06-30 株式会社Ｎｒｌファーマ 更年期障害改善用医薬組成物ならびに飲食物

Also Published As

Publication number Publication date
FR2574800A1 (fr) 1986-06-20
AU585543B2 (en) 1989-06-22
NZ213985A (en) 1989-02-24
US4668771A (en) 1987-05-26
JPH0566397B2 (https=) 1993-09-21
GB2168982A (en) 1986-07-02
AU4922785A (en) 1986-06-26
FR2574800B1 (fr) 1989-11-17
GB8530898D0 (en) 1986-01-29
DE3544400A1 (de) 1986-06-26
GB2168982B (en) 1989-02-01
BE903886A (fr) 1986-04-16

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees