JPS568354A - Novel tripeptide and said manufacture - Google Patents

Novel tripeptide and said manufacture

Info

Publication number
JPS568354A
JPS568354A JP8723680A JP8723680A JPS568354A JP S568354 A JPS568354 A JP S568354A JP 8723680 A JP8723680 A JP 8723680A JP 8723680 A JP8723680 A JP 8723680A JP S568354 A JPS568354 A JP S568354A
Authority
JP
Japan
Prior art keywords
manufacture
novel tripeptide
tripeptide
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8723680A
Other languages
English (en)
Other versions
JPH0159278B2 (ja
Inventor
Kisufuarudei Rayosu
Sujirutesu Tamasu
Barasupiri Rayosu
Paroshi Eba
Suzuporunii Rasuzuro
Sarukadei Adamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of JPS568354A publication Critical patent/JPS568354A/ja
Publication of JPH0159278B2 publication Critical patent/JPH0159278B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP8723680A 1979-06-28 1980-06-26 Novel tripeptide and said manufacture Granted JPS568354A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79RI718A HU180926B (en) 1979-06-28 1979-06-28 Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem

Publications (2)

Publication Number Publication Date
JPS568354A true JPS568354A (en) 1981-01-28
JPH0159278B2 JPH0159278B2 (ja) 1989-12-15

Family

ID=11001101

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8723680A Granted JPS568354A (en) 1979-06-28 1980-06-26 Novel tripeptide and said manufacture

Country Status (23)

Country Link
US (1) US4386073A (ja)
JP (1) JPS568354A (ja)
AT (1) AT380259B (ja)
AU (1) AU538621B2 (ja)
BE (1) BE884015A (ja)
BG (1) BG60739B2 (ja)
CA (1) CA1188296A (ja)
CH (1) CH650519A5 (ja)
CS (1) CS241028B2 (ja)
DD (1) DD151745A5 (ja)
DE (1) DE3024256A1 (ja)
DK (1) DK149610C (ja)
FI (1) FI73224C (ja)
FR (1) FR2460291A1 (ja)
GB (1) GB2058079B (ja)
HU (1) HU180926B (ja)
IL (1) IL60406A (ja)
IT (1) IT1174678B (ja)
NL (1) NL192575C (ja)
PL (1) PL123822B1 (ja)
SE (1) SE447389B (ja)
SU (1) SU1085505A3 (ja)
YU (1) YU43220B (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60190795A (ja) * 1984-03-09 1985-09-28 Takeda Chem Ind Ltd ペプタイド
JPS6110596A (ja) * 1983-09-07 1986-01-18 Tanabe Seiyaku Co Ltd 新規ペプタイド
JPS6222797A (ja) * 1985-07-19 1987-01-30 Tanabe Seiyaku Co Ltd 新規ペプタイド

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184481B (en) * 1981-10-02 1984-08-28 Richter Gedeon Vegyeszet Process for producing tripeptides for diminishing appetite
CA1256650A (en) * 1983-03-25 1989-06-27 Toshinari Tamura Process of producing 2-azetidinone-4-substituted compounds, and medicaments containing the compounds
US4608365A (en) * 1984-03-30 1986-08-26 University Of Southern California Treatment of neurologic functions
US4719207A (en) * 1984-06-25 1988-01-12 Yamanouchi Pharmaceutical Co., Ltd. CNS active substituted azetidinone compounds
IL75641A (en) * 1984-07-10 1990-11-05 Tanabe Seiyaku Co 1-methyl-4,5-dihydro-orotyl-histidyl-prolinamide,its preparation and pharmaceutical compositions comprising it
IE58849B1 (en) * 1984-12-18 1993-11-17 Gruenenthal Chemie Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
JPH06104079B2 (ja) * 1988-07-14 1994-12-21 日東紡績株式会社 新規な酵素活性測定用基質
FR2649110B1 (fr) * 1989-06-29 1994-10-21 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP0473993B1 (en) * 1990-08-17 1996-04-17 Japan Tobacco Inc. Novel peptide derivatives and their pharmaceutical use
HU206374B (en) * 1990-09-03 1992-10-28 Richter Gedeon Vegyeszet Process for producing pentapeptide and its salts specifically inhibiting proliferation of epidermic cells, as well as pharmaceutical compositions comprising same as active ingredient
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
US20050233973A1 (en) * 1997-10-09 2005-10-20 Albert Sattin Tri-peptides for antidepressant applications
US20020151502A1 (en) * 1997-10-09 2002-10-17 Albert Sattin Tri-peptides for neurological and neurobehavior applications
US20030175350A1 (en) * 2000-07-11 2003-09-18 Katsuji Sugita Enteric preparations containing physiologically active peptides
EP1321151A4 (en) * 2000-08-31 2009-07-15 Shionogi & Co MEANS FOR THE TREATMENT OF PARKINSON
US8143369B2 (en) * 2009-06-02 2012-03-27 International Business Machines Corporation Polymers bearing pendant pentafluorophenyl ester groups, and methods of synthesis and functionalization thereof
JP6847948B2 (ja) * 2016-07-14 2021-03-24 昭和電工株式会社 メラニン産生抑制剤、美白剤、線維芽細胞活性化剤、コラーゲン及び／又はエラスチン産生促進剤、及びシワ改善剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2343037A1 (de) * 1973-08-25 1975-03-06 Hoechst Ag Arzneimittel mit antidepressiver wirkung
US3959248A (en) * 1974-04-03 1976-05-25 Merck & Co., Inc. Analogs of thyrotropin-releasing hormone
DE2449167C2 (de) * 1974-10-16 1984-05-24 Grünenthal GmbH, 5190 Stolberg N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
SE408300B (sv) * 1974-10-16 1979-06-05 Gruenenthal Chemie Sett att framstella nya dipeptidderivat
JPS5944308B2 (ja) * 1976-03-23 1984-10-29 武田薬品工業株式会社 ペプタイド

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6110596A (ja) * 1983-09-07 1986-01-18 Tanabe Seiyaku Co Ltd 新規ペプタイド
JPS60190795A (ja) * 1984-03-09 1985-09-28 Takeda Chem Ind Ltd ペプタイド
JPH0564160B2 (ja) * 1984-03-09 1993-09-14 Takeda Chemical Industries Ltd
JPS6222797A (ja) * 1985-07-19 1987-01-30 Tanabe Seiyaku Co Ltd 新規ペプタイド

Also Published As

Publication number Publication date
BE884015A (fr) 1980-12-29
AU5972080A (en) 1981-01-08
DD151745A5 (de) 1981-11-04
NL8003766A (nl) 1980-12-30
GB2058079A (en) 1981-04-08
DE3024256A1 (de) 1981-01-08
IL60406A (en) 1984-10-31
NL192575B (nl) 1997-06-02
FI73224C (fi) 1987-09-10
CA1188296A (en) 1985-06-04
SE8004745L (sv) 1980-12-29
BG60739B2 (bg) 1996-01-31
DK149610B (da) 1986-08-11
IT1174678B (it) 1987-07-01
SU1085505A3 (ru) 1984-04-07
JPH0159278B2 (ja) 1989-12-15
NL192575C (nl) 1997-10-03
FR2460291A1 (fr) 1981-01-23
SE447389B (sv) 1986-11-10
IL60406A0 (en) 1980-09-16
IT8023097A0 (it) 1980-06-26
YU169580A (en) 1984-04-30
DE3024256C2 (ja) 1991-01-24
PL225269A1 (ja) 1981-05-08
DK149610C (da) 1987-05-04
ATA334780A (de) 1985-09-15
YU43220B (en) 1989-06-30
FI73224B (fi) 1987-05-29
CS241028B2 (en) 1986-03-13
AT380259B (de) 1986-05-12
DK274580A (da) 1980-12-29
FI802058A (fi) 1980-12-29
CS458380A2 (en) 1985-06-13
FR2460291B1 (ja) 1984-11-23
US4386073A (en) 1983-05-31
GB2058079B (en) 1983-03-02
CH650519A5 (de) 1985-07-31
AU538621B2 (en) 1984-08-23
PL123822B1 (en) 1982-11-30
HU180926B (en) 1983-05-30

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