IT1202426B - Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono - Google Patents

Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono

Info

Publication number
IT1202426B
IT1202426B IT19165/87A IT1916587A IT1202426B IT 1202426 B IT1202426 B IT 1202426B IT 19165/87 A IT19165/87 A IT 19165/87A IT 1916587 A IT1916587 A IT 1916587A IT 1202426 B IT1202426 B IT 1202426B
Authority
IT
Italy
Prior art keywords
carboxylic acid
thiazolidin
contain
preparation
pharmaceutical compositions
Prior art date
Application number
IT19165/87A
Other languages
English (en)
Other versions
IT8719165A0 (it
Inventor
Stefano Poli
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of IT8719165A0 publication Critical patent/IT8719165A0/it
Priority to IT19165/87A priority Critical patent/IT1202426B/it
Priority to CA000556249A priority patent/CA1326029C/en
Priority to IL85102A priority patent/IL85102A/xx
Priority to US07/144,528 priority patent/US4839387A/en
Priority to ZA880379A priority patent/ZA88379B/xx
Priority to AT88100825T priority patent/ATE67212T1/de
Priority to AU10673/88A priority patent/AU613890B2/en
Priority to ES198888100825T priority patent/ES2003856T3/es
Priority to DE198888100825T priority patent/DE276752T1/de
Priority to EP88100825A priority patent/EP0276752B1/en
Priority to DE8888100825T priority patent/DE3864691D1/de
Priority to NZ223287A priority patent/NZ223287A/xx
Priority to KR1019880000537A priority patent/KR960005167B1/ko
Priority to HU88278A priority patent/HU202867B/hu
Priority to JP63012762A priority patent/JPS63201187A/ja
Priority to FI880324A priority patent/FI89369C/fi
Priority to DK032288A priority patent/DK171789B1/da
Priority to IE17888A priority patent/IE60185B1/en
Priority to NO880332A priority patent/NO170686C/no
Priority to GR88300151T priority patent/GR880300151T1/el
Application granted granted Critical
Publication of IT1202426B publication Critical patent/IT1202426B/it
Priority to GR91401668T priority patent/GR3003060T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IT19165/87A 1987-01-26 1987-01-26 Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono IT1202426B (it)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IT19165/87A IT1202426B (it) 1987-01-26 1987-01-26 Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
CA000556249A CA1326029C (en) 1987-01-26 1988-01-11 4-thiazolidine-carboxylic acid derivative, its preparation and pharmaceutical compositions containing it
IL85102A IL85102A (en) 1987-01-26 1988-01-14 4-thiazolidinecarboxylic acid derivative, its preparation and pharmaceutical compositions containing it
US07/144,528 US4839387A (en) 1987-01-26 1988-01-15 Derivative of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
ZA880379A ZA88379B (en) 1987-01-26 1988-01-20 4-thiazolidinecarboxylic acid derivative,its preparation and pharmaceutical compositions containing it
DE8888100825T DE3864691D1 (de) 1987-01-26 1988-01-21 Thiazolidin-4-carbonsaeurederivat, seine herstellung und pharmazeutische zusammensetzungen, die dieses enthalten.
AU10673/88A AU613890B2 (en) 1987-01-26 1988-01-21 4-thiazolidinecarboxylic acid derivative, its preparation and pharmaceutical compositions containing it
ES198888100825T ES2003856T3 (es) 1987-01-26 1988-01-21 Derivado del acido tiazolidin-4-carboxilico, su preparacion y composiciones farmaceuticas que lo contienen.
DE198888100825T DE276752T1 (de) 1987-01-26 1988-01-21 Thiazolidin-4-carbonsaeurederivat, seine herstellung und pharmazeutische zusammensetzungen, die dieses enthalten.
EP88100825A EP0276752B1 (en) 1987-01-26 1988-01-21 Derivative of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
AT88100825T ATE67212T1 (de) 1987-01-26 1988-01-21 Thiazolidin-4-carbonsaeurederivat, seine herstellung und pharmazeutische zusammensetzungen, die dieses enthalten.
NZ223287A NZ223287A (en) 1987-01-26 1988-01-22 4-thiazolidine carboxylic acid derivatives and pharmaceutical compositions
JP63012762A JPS63201187A (ja) 1987-01-26 1988-01-25 ４−チアゾリジンカルボン酸誘導体、その製造法および医薬品組成物
HU88278A HU202867B (en) 1987-01-26 1988-01-25 Process for producing new 4-thiadiazolidine-carboxylic acid derivatives and pharmaceutical compositions containing them as active components
KR1019880000537A KR960005167B1 (ko) 1987-01-26 1988-01-25 3-l-피로글루타밀-l-티아졸리딘-4-카르복실산 및 그 제조 방법
FI880324A FI89369C (fi) 1987-01-26 1988-01-25 Foerfarande foer framstaellning av farmaceutiskt aktiv 3-l-pyroglutamoyl-l-tiazolidin-4-karboxylsyra
DK032288A DK171789B1 (da) 1987-01-26 1988-01-25 4-Thiazolidincarboxylsyrederivat, dets fremstilli ng og lægemidler, der indeholder det
IE17888A IE60185B1 (en) 1987-01-26 1988-01-25 Derivative of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
NO880332A NO170686C (no) 1987-01-26 1988-01-26 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 3-l-pyroglutamyl-l-tiazolidin-4-karboksylsyre
GR88300151T GR880300151T1 (en) 1987-01-26 1989-01-31 Derivative of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
GR91401668T GR3003060T3 (en) 1987-01-26 1991-11-04 Derivative of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19165/87A IT1202426B (it) 1987-01-26 1987-01-26 Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono

Publications (2)

Publication Number Publication Date
IT8719165A0 IT8719165A0 (it) 1987-01-26
IT1202426B true IT1202426B (it) 1989-02-09

Family

ID=11155438

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19165/87A IT1202426B (it) 1987-01-26 1987-01-26 Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono

Country Status (19)

Country Link
US (1) US4839387A (it)
EP (1) EP0276752B1 (it)
JP (1) JPS63201187A (it)
KR (1) KR960005167B1 (it)
AT (1) ATE67212T1 (it)
AU (1) AU613890B2 (it)
CA (1) CA1326029C (it)
DE (2) DE276752T1 (it)
DK (1) DK171789B1 (it)
ES (1) ES2003856T3 (it)
FI (1) FI89369C (it)
GR (2) GR880300151T1 (it)
HU (1) HU202867B (it)
IE (1) IE60185B1 (it)
IL (1) IL85102A (it)
IT (1) IT1202426B (it)
NO (1) NO170686C (it)
NZ (1) NZ223287A (it)
ZA (1) ZA88379B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230706B (it) * 1989-02-10 1991-10-29 Poli Ind Chimica Spa Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.
IT1239029B (it) * 1989-10-12 1993-09-20 Poli Ind Chimica Spa Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati.
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono
IT1240353B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci immunomodulatori per applicazionelocale ed aerosolica
EP0715853A1 (en) * 1991-01-10 1996-06-12 Transcend Therapeutics, Inc. Use of glutathione esters for the treatment of pulmonary diseases
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
FR2675692A1 (fr) * 1991-04-24 1992-10-30 Oreal Systeme anti-oxydant contenant du pyrrolidone carboxylate de lysine et/ou du pyrrolidone carboxylate d'arginine soit seul soit associe a un derive phenolique et son utilisation en cosmetique.
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
IT1264446B1 (it) * 1993-05-14 1996-09-23 Yason Srl Acido 3 (n-(2-mercapto-propionil-ammino-acetil))-tetraidrotiazolil-4- carbossilico come agente antiinfiammatorio e immunostimolante
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
IT1270017B (it) * 1994-09-27 1997-04-16 Poli Ind Chimica Spa "sintesi quantitativa dell'acido 3-(l-piroglutamil)-l-tiazolidin-4- carbossilico e suoi derivati"
DE19711053C2 (de) * 1997-03-03 1999-09-02 Rommelspacher Kombinationspräparat aus 2-Methyl-thiazolidin-2,4-dicarbonsäure und Paracetamol
CN104059106B (zh) * 2014-06-27 2017-02-15 魏景芬 一种磷酸糖醇类四氢噻唑‑4‑羧酸化合物的制备方法
CN104059107A (zh) * 2014-06-27 2014-09-24 魏景芬 一种磷酸糖醇类四氢噻唑-4-羧酸化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959248A (en) * 1974-04-03 1976-05-25 Merck & Co., Inc. Analogs of thyrotropin-releasing hormone
US4085954A (en) * 1974-06-03 1978-04-25 Thompson Omer A Slat assembly for chain link fence
GB1492640A (en) * 1975-07-08 1977-11-23 Ucb Sa L-pyroglutamyl-l-prolinamide
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem

Also Published As

Publication number Publication date
FI89369C (fi) 1993-09-27
US4839387A (en) 1989-06-13
NZ223287A (en) 1990-06-26
IL85102A0 (en) 1988-06-30
NO880332D0 (no) 1988-01-26
DK32288D0 (da) 1988-01-25
GR880300151T1 (en) 1989-01-31
NO170686B (no) 1992-08-10
GR3003060T3 (en) 1993-02-17
NO170686C (no) 1992-11-18
AU1067388A (en) 1988-07-28
DE276752T1 (de) 1989-01-05
EP0276752A1 (en) 1988-08-03
KR960005167B1 (ko) 1996-04-22
AU613890B2 (en) 1991-08-15
IE880178L (en) 1988-07-26
ATE67212T1 (de) 1991-09-15
FI880324A (fi) 1988-07-27
HUT50338A (en) 1990-01-29
NO880332L (no) 1988-07-27
IL85102A (en) 1993-02-21
IT8719165A0 (it) 1987-01-26
KR880009018A (ko) 1988-09-13
ES2003856T3 (es) 1992-05-01
HU202867B (en) 1991-04-29
DK171789B1 (da) 1997-05-26
IE60185B1 (en) 1994-06-15
FI880324A0 (fi) 1988-01-25
JPS63201187A (ja) 1988-08-19
EP0276752B1 (en) 1991-09-11
DE3864691D1 (de) 1991-10-17
FI89369B (fi) 1993-06-15
DK32288A (da) 1988-07-27
ZA88379B (en) 1988-07-05
CA1326029C (en) 1994-01-11
ES2003856A4 (es) 1988-12-01
JPH0515713B2 (it) 1993-03-02

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