ES2003856T3 - Derivado del acido tiazolidin-4-carboxilico, su preparacion y composiciones farmaceuticas que lo contienen. - Google Patents

Derivado del acido tiazolidin-4-carboxilico, su preparacion y composiciones farmaceuticas que lo contienen.

Info

Publication number
ES2003856T3
ES2003856T3 ES198888100825T ES88100825T ES2003856T3 ES 2003856 T3 ES2003856 T3 ES 2003856T3 ES 198888100825 T ES198888100825 T ES 198888100825T ES 88100825 T ES88100825 T ES 88100825T ES 2003856 T3 ES2003856 T3 ES 2003856T3
Authority
ES
Spain
Prior art keywords
acid
tiazolidin
carboxilico
derived
contain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888100825T
Other languages
English (en)
Other versions
ES2003856A4 (es
Inventor
Stefano Dr. Poli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poli Industria Chimica SpA
Original Assignee
Poli Industria Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Industria Chimica SpA filed Critical Poli Industria Chimica SpA
Publication of ES2003856A4 publication Critical patent/ES2003856A4/es
Application granted granted Critical
Publication of ES2003856T3 publication Critical patent/ES2003856T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

EL ACIDO 3-L-PIROGLUTAMOIL-TRIAZOLIDIN-4-CARBOXILICO, PREPARADO A PARTIR DE UN ESTER ACTIVADO DEL ACIDO L-PIROGLUTAMICO A PARTIR DE CLORURO DE PIROGLUTAMOILO Y ACIDO L-TIAZOLIDIN-4-CARBOXILICO, MUESTRA INTERESANTES PROPIEDADES INMUNOESTIMULANTES, ANTITOXICAS, ANTIINFLAMATORIAS, ANTIOXIDANTES Y ANTIENVEJECIMIENTO.
ES198888100825T 1987-01-26 1988-01-21 Derivado del acido tiazolidin-4-carboxilico, su preparacion y composiciones farmaceuticas que lo contienen. Expired - Lifetime ES2003856T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19165/87A IT1202426B (it) 1987-01-26 1987-01-26 Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono

Publications (2)

Publication Number Publication Date
ES2003856A4 ES2003856A4 (es) 1988-12-01
ES2003856T3 true ES2003856T3 (es) 1992-05-01

Family

ID=11155438

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888100825T Expired - Lifetime ES2003856T3 (es) 1987-01-26 1988-01-21 Derivado del acido tiazolidin-4-carboxilico, su preparacion y composiciones farmaceuticas que lo contienen.

Country Status (19)

Country Link
US (1) US4839387A (es)
EP (1) EP0276752B1 (es)
JP (1) JPS63201187A (es)
KR (1) KR960005167B1 (es)
AT (1) ATE67212T1 (es)
AU (1) AU613890B2 (es)
CA (1) CA1326029C (es)
DE (2) DE3864691D1 (es)
DK (1) DK171789B1 (es)
ES (1) ES2003856T3 (es)
FI (1) FI89369C (es)
GR (2) GR880300151T1 (es)
HU (1) HU202867B (es)
IE (1) IE60185B1 (es)
IL (1) IL85102A (es)
IT (1) IT1202426B (es)
NO (1) NO170686C (es)
NZ (1) NZ223287A (es)
ZA (1) ZA88379B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230706B (it) * 1989-02-10 1991-10-29 Poli Ind Chimica Spa Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.
IT1239029B (it) * 1989-10-12 1993-09-20 Poli Ind Chimica Spa Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati.
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono
IT1240353B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci immunomodulatori per applicazionelocale ed aerosolica
EP0494405B2 (en) * 1991-01-10 2000-04-19 Transcend Therapeutics, Inc. Use of L-2-oxo thiazolidine-4-carboxylate for the treatment of pulmonary diseases
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
FR2675692A1 (fr) * 1991-04-24 1992-10-30 Oreal Systeme anti-oxydant contenant du pyrrolidone carboxylate de lysine et/ou du pyrrolidone carboxylate d'arginine soit seul soit associe a un derive phenolique et son utilisation en cosmetique.
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
IT1264446B1 (it) * 1993-05-14 1996-09-23 Yason Srl Acido 3 (n-(2-mercapto-propionil-ammino-acetil))-tetraidrotiazolil-4- carbossilico come agente antiinfiammatorio e immunostimolante
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
IT1270017B (it) * 1994-09-27 1997-04-16 Poli Ind Chimica Spa "sintesi quantitativa dell'acido 3-(l-piroglutamil)-l-tiazolidin-4- carbossilico e suoi derivati"
DE19711053C2 (de) * 1997-03-03 1999-09-02 Rommelspacher Kombinationspräparat aus 2-Methyl-thiazolidin-2,4-dicarbonsäure und Paracetamol
CN104059106B (zh) * 2014-06-27 2017-02-15 魏景芬 一种磷酸糖醇类四氢噻唑‑4‑羧酸化合物的制备方法
CN104059107A (zh) * 2014-06-27 2014-09-24 魏景芬 一种磷酸糖醇类四氢噻唑-4-羧酸化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959248A (en) * 1974-04-03 1976-05-25 Merck & Co., Inc. Analogs of thyrotropin-releasing hormone
US4085954A (en) * 1974-06-03 1978-04-25 Thompson Omer A Slat assembly for chain link fence
GB1492640A (en) * 1975-07-08 1977-11-23 Ucb Sa L-pyroglutamyl-l-prolinamide
HU180926B (en) * 1979-06-28 1983-05-30 Richter Gedeon Vegyeszet Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem

Also Published As

Publication number Publication date
ES2003856A4 (es) 1988-12-01
JPS63201187A (ja) 1988-08-19
DK171789B1 (da) 1997-05-26
DK32288A (da) 1988-07-27
DE276752T1 (de) 1989-01-05
KR880009018A (ko) 1988-09-13
ZA88379B (en) 1988-07-05
IT1202426B (it) 1989-02-09
IL85102A (en) 1993-02-21
CA1326029C (en) 1994-01-11
NZ223287A (en) 1990-06-26
IE60185B1 (en) 1994-06-15
EP0276752B1 (en) 1991-09-11
US4839387A (en) 1989-06-13
EP0276752A1 (en) 1988-08-03
FI880324A0 (fi) 1988-01-25
NO880332D0 (no) 1988-01-26
NO170686C (no) 1992-11-18
IE880178L (en) 1988-07-26
NO880332L (no) 1988-07-27
HUT50338A (en) 1990-01-29
NO170686B (no) 1992-08-10
IT8719165A0 (it) 1987-01-26
IL85102A0 (en) 1988-06-30
GR880300151T1 (en) 1989-01-31
DE3864691D1 (de) 1991-10-17
FI89369B (fi) 1993-06-15
HU202867B (en) 1991-04-29
AU613890B2 (en) 1991-08-15
DK32288D0 (da) 1988-01-25
KR960005167B1 (ko) 1996-04-22
GR3003060T3 (en) 1993-02-17
FI880324A (fi) 1988-07-27
AU1067388A (en) 1988-07-28
JPH0515713B2 (es) 1993-03-02
ATE67212T1 (de) 1991-09-15
FI89369C (fi) 1993-09-27

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