IT1230706B - Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche. - Google Patents

Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.

Info

Publication number
IT1230706B
IT1230706B IT8919401A IT1940189A IT1230706B IT 1230706 B IT1230706 B IT 1230706B IT 8919401 A IT8919401 A IT 8919401A IT 1940189 A IT1940189 A IT 1940189A IT 1230706 B IT1230706 B IT 1230706B
Authority
IT
Italy
Prior art keywords
derivatives
carboxylic
piroglutamoil
thiazolidin
acid
Prior art date
Application number
IT8919401A
Other languages
English (en)
Other versions
IT8919401A0 (it
Inventor
Stefano Poli
Germano Coppi
Lucio Del Corona
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of IT8919401A0 publication Critical patent/IT8919401A0/it
Priority to IT8919401A priority Critical patent/IT1230706B/it
Priority to IE900261A priority patent/IE900261L/xx
Priority to IL9319790A priority patent/IL93197A/en
Priority to ZA90645A priority patent/ZA90645B/xx
Priority to DE69009211T priority patent/DE69009211T2/de
Priority to EP90102388A priority patent/EP0382180B1/en
Priority to AT90102388T priority patent/ATE106407T1/de
Priority to ES90102388T priority patent/ES2017900T3/es
Priority to DE199090102388T priority patent/DE382180T1/de
Priority to NZ232437A priority patent/NZ232437A/en
Priority to HU90717A priority patent/HU209602B/hu
Priority to NO90900644A priority patent/NO900644L/no
Priority to US07/477,507 priority patent/US5066644A/en
Priority to JP2028631A priority patent/JPH02250896A/ja
Priority to CA002009709A priority patent/CA2009709A1/en
Priority to FI900665A priority patent/FI900665A7/fi
Priority to AU49271/90A priority patent/AU630661B2/en
Priority to KR1019900001615A priority patent/KR910015574A/ko
Priority to GR90300167T priority patent/GR900300167T1/el
Application granted granted Critical
Publication of IT1230706B publication Critical patent/IT1230706B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT8919401A 1989-02-10 1989-02-10 Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche. IT1230706B (it)

Priority Applications (19)

Application Number Priority Date Filing Date Title
IT8919401A IT1230706B (it) 1989-02-10 1989-02-10 Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.
IE900261A IE900261L (en) 1989-02-10 1990-01-23 Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid¹and their pharmacological properties
IL9319790A IL93197A (en) 1989-02-10 1990-01-28 Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid
ZA90645A ZA90645B (en) 1989-02-10 1990-01-29 Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties
DE199090102388T DE382180T1 (de) 1989-02-10 1990-02-07 Derivate von thiazolidin-4-carbonsaeure, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
EP90102388A EP0382180B1 (en) 1989-02-10 1990-02-07 Derivatives of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
AT90102388T ATE106407T1 (de) 1989-02-10 1990-02-07 Derivate von thiazolidin-4-carbonsäure, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES90102388T ES2017900T3 (es) 1989-02-10 1990-02-07 Derivados del acido tiazolidin-4-carboxilico, su preparacion y composiciones farmaceuticas que lo contienen.
DE69009211T DE69009211T2 (de) 1989-02-10 1990-02-07 Derivate von Thiazolidin-4-carbonsäure, deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen.
NZ232437A NZ232437A (en) 1989-02-10 1990-02-08 3-pyroglutamyl-thiazolidine-4-carboxylic acid derivatives; preparatory processes and pharmaceutical compositions
HU90717A HU209602B (en) 1989-02-10 1990-02-08 Process for producing 3-(l-pyroglutamyl)-l-thiazolidine-4-carboxylic acid derivatives and pharmaceutical compositions containing them as active components
JP2028631A JPH02250896A (ja) 1989-02-10 1990-02-09 ３―ピログルタミル―チアゾリジン―４―カルボン酸誘導体
US07/477,507 US5066644A (en) 1989-02-10 1990-02-09 Derivatives of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it
NO90900644A NO900644L (no) 1989-02-10 1990-02-09 3-pyroglutamyl-tiazolidin-4-karboksylsyrederivater og deres farmakologiske egenskaper.
CA002009709A CA2009709A1 (en) 1989-02-10 1990-02-09 Derivatives of 3-pyroglutamyl-thiazolidine-4-carboxylic acid and their pharmacological properties
FI900665A FI900665A7 (fi) 1989-02-10 1990-02-09 3-pyroglutamyl-tiatsolidiini-4-karboksyylihappojohdannaiset ja niiden farmakologiset ominaisuudet
AU49271/90A AU630661B2 (en) 1989-02-10 1990-02-09 Derivatives of 3-(l-pyroglutamyl)-l-thiazolidine-4-carboxylic acid and their pharmacological properties
KR1019900001615A KR910015574A (ko) 1989-02-10 1990-02-10 3-피로글루타밀-티아졸리딘-4-카르복실산의 유도체 및 그들의 약리학적 작용
GR90300167T GR900300167T1 (en) 1989-02-10 1991-09-27 Derivatives of thiazolidine-4-carboxylic acid, its preparation and pharmaceutical compositions containing it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8919401A IT1230706B (it) 1989-02-10 1989-02-10 Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.

Publications (2)

Publication Number Publication Date
IT8919401A0 IT8919401A0 (it) 1989-02-10
IT1230706B true IT1230706B (it) 1991-10-29

Family

ID=11157390

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8919401A IT1230706B (it) 1989-02-10 1989-02-10 Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.

Country Status (18)

Country Link
US (1) US5066644A (it)
EP (1) EP0382180B1 (it)
JP (1) JPH02250896A (it)
KR (1) KR910015574A (it)
AT (1) ATE106407T1 (it)
AU (1) AU630661B2 (it)
CA (1) CA2009709A1 (it)
DE (2) DE69009211T2 (it)
ES (1) ES2017900T3 (it)
FI (1) FI900665A7 (it)
GR (1) GR900300167T1 (it)
HU (1) HU209602B (it)
IE (1) IE900261L (it)
IL (1) IL93197A (it)
IT (1) IT1230706B (it)
NO (1) NO900644L (it)
NZ (1) NZ232437A (it)
ZA (1) ZA90645B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
US5369127A (en) * 1993-04-21 1994-11-29 Allergan, Inc. 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents
US5710288A (en) * 1993-04-21 1998-01-20 Allergan 1,3-benzodioxole and 1,2-dialkoxybenzene derivatives as ocular hypotensive agents
WO2015036009A1 (en) * 2013-09-10 2015-03-19 Polichem S.A. Pidotimod for use in the treatment of inflammation-associated diseases
CN111233854A (zh) * 2019-12-30 2020-06-05 常州寅盛药业有限公司 一种匹多莫德杂质的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1492640A (en) * 1975-07-08 1977-11-23 Ucb Sa L-pyroglutamyl-l-prolinamide
IT1196485B (it) * 1986-07-14 1988-11-16 Zambon Spa Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono
IT1223565B (it) * 1987-12-21 1990-09-19 Zambon Spa Derivati dell'acido tiazolidin 4 carbossilico ad attivita' farmaceutica
CA2004028C (en) * 1988-12-08 1998-09-22 Motoki Torizuka Condensed benzene derivative
IT1239029B (it) * 1989-10-12 1993-09-20 Poli Ind Chimica Spa Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati.
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
AU4927190A (en) 1990-08-16
FI900665A7 (fi) 1990-08-11
GR900300167T1 (en) 1991-09-27
NO900644L (no) 1990-08-13
ES2017900A4 (es) 1991-03-16
HU209602B (en) 1994-09-28
KR910015574A (ko) 1991-09-30
IL93197A (en) 1994-08-26
ES2017900T3 (es) 1994-08-01
NZ232437A (en) 1991-06-25
EP0382180A3 (en) 1990-11-28
IL93197A0 (en) 1990-11-05
ATE106407T1 (de) 1994-06-15
US5066644A (en) 1991-11-19
EP0382180B1 (en) 1994-06-01
HUT58089A (en) 1992-01-28
ZA90645B (en) 1990-10-31
JPH02250896A (ja) 1990-10-08
CA2009709A1 (en) 1990-08-10
DE69009211D1 (de) 1994-07-07
NO900644D0 (no) 1990-02-09
DE69009211T2 (de) 1994-10-27
HU900717D0 (en) 1990-04-28
IE900261L (en) 1990-08-10
AU630661B2 (en) 1992-11-05
DE382180T1 (de) 1991-02-07
IT8919401A0 (it) 1989-02-10
FI900665A0 (fi) 1990-02-09
EP0382180A2 (en) 1990-08-16

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970226