JPS5422996B2 - - Google Patents

Info

Publication number
JPS5422996B2
JPS5422996B2 JP75132198A JP13219875A JPS5422996B2 JP S5422996 B2 JPS5422996 B2 JP S5422996B2 JP 75132198 A JP75132198 A JP 75132198A JP 13219875 A JP13219875 A JP 13219875A JP S5422996 B2 JPS5422996 B2 JP S5422996B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP75132198A
Other languages
Japanese (ja)
Other versions
JPS5170776A (OSRAM
Inventor
Kotoreru Kuroodo
Kurisan Koruneru
Janmaaru Kuroodo
Noomu Mutsuse Meieru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7436963A external-priority patent/FR2313060A1/fr
Priority claimed from FR7527161A external-priority patent/FR2322601A1/fr
Priority claimed from FR7527160A external-priority patent/FR2322600A1/fr
Priority claimed from FR7527162A external-priority patent/FR2322602A1/fr
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Publication of JPS5170776A publication Critical patent/JPS5170776A/ja
Publication of JPS5422996B2 publication Critical patent/JPS5422996B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP75132198A 1974-11-07 1975-11-05 Expired JPS5422996B2 (OSRAM)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7436963A FR2313060A1 (fr) 1974-11-07 1974-11-07 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527161A FR2322601A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527160A FR2322600A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de la pyrrolo (3,4-b) pyrazine, leur preparation et les compositions qui les contiennent
FR7527162A FR2322602A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'oxathiinno- et du dithiinnopyrrole, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
JPS5170776A JPS5170776A (OSRAM) 1976-06-18
JPS5422996B2 true JPS5422996B2 (OSRAM) 1979-08-10

Family

ID=27446274

Family Applications (2)

Application Number Title Priority Date Filing Date
JP75132198A Expired JPS5422996B2 (OSRAM) 1974-11-07 1975-11-05
JP12525778A Granted JPS5498790A (en) 1974-11-07 1978-10-13 Manufacture of novel heterocyclic compound

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP12525778A Granted JPS5498790A (en) 1974-11-07 1978-10-13 Manufacture of novel heterocyclic compound

Country Status (27)

Country Link
US (1) US4220646A (OSRAM)
JP (2) JPS5422996B2 (OSRAM)
AR (2) AR208414A1 (OSRAM)
AT (2) AT343123B (OSRAM)
AU (1) AU503200B2 (OSRAM)
BE (1) BE835325A (OSRAM)
CA (1) CA1057755A (OSRAM)
CH (1) CH609057A5 (OSRAM)
CS (2) CS231957B2 (OSRAM)
CY (1) CY1045A (OSRAM)
DD (1) DD122684A5 (OSRAM)
DE (1) DE2550111C2 (OSRAM)
DK (1) DK141098B (OSRAM)
FI (1) FI60707C (OSRAM)
GB (1) GB1468497A (OSRAM)
HK (1) HK19380A (OSRAM)
HU (1) HU173108B (OSRAM)
IE (1) IE41928B1 (OSRAM)
IL (1) IL48423A (OSRAM)
LU (1) LU73738A1 (OSRAM)
NL (1) NL177405C (OSRAM)
NO (1) NO143576C (OSRAM)
OA (1) OA05162A (OSRAM)
PL (1) PL101248B1 (OSRAM)
SE (1) SE407063B (OSRAM)
SU (2) SU673173A3 (OSRAM)
YU (2) YU39583B (OSRAM)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2371198A2 (fr) * 1976-11-22 1978-06-16 Rhone Poulenc Ind Nouveaux derives du dithiepinno (1,4)(2,3-c) pyrrole, leur preparation et les compositions qui les contiennent
US4533751A (en) * 1981-10-09 1985-08-06 Scm Corporation Preparation of 1,3-dienamines from myrcene and substituted myrcene
FR2525606A1 (fr) * 1982-04-22 1983-10-28 Rhone Poulenc Sante Nouveaux derives du dithiino (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2671800B1 (fr) * 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.
US5786357A (en) * 1991-12-02 1998-07-28 Sepracor Inc. Methods and compositions for treating sleep disorders, convulsive seizures and other disorders using optically pure (+) zopiclone
HU214331B (hu) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
TW279864B (OSRAM) * 1993-02-19 1996-07-01 Janssen Pharmaceutica Nv
US5565567A (en) * 1993-06-04 1996-10-15 Henkel Corporation. Polymerizable N,N'-substituted piperazine acrylamide compounds
CN1126474A (zh) * 1993-06-04 1996-07-10 亨凯尔公司 聚合的化合物
US5922820A (en) * 1993-06-04 1999-07-13 Henkel Corporation Polymerizable compounds
CN1160398A (zh) * 1994-09-23 1997-09-24 阿瑞斯药物公司 治疗肥大细胞炎性疾病的组合物和方法
US5663357A (en) 1995-11-22 1997-09-02 Allergan Substituted heteroarylamides having retinoid-like biological activity
US5756742A (en) * 1995-12-22 1998-05-26 Henkel Corporation Polymerizable compounds
US6339086B1 (en) 1999-05-14 2002-01-15 Swpracor, Inc. Methods of making and using N-desmethylzopiclone
US7902179B2 (en) * 2001-04-26 2011-03-08 Ajinomoto Co., Inc. Heterocyclic compounds
PT1490363E (pt) * 2002-03-29 2006-06-30 Indevus Pharmaceuticals Inc Processos de preparacao da 2-(7-cloro-1,8-naftiridina-2-il)-3-(5-metil-2-oxo-hexil)-1-isoindolinona
WO2004037212A2 (en) * 2002-10-24 2004-05-06 Sepracor, Inc. Compositions comprising zopiclone derivatives and methods of making and using the same
US6909002B2 (en) * 2002-11-22 2005-06-21 Merck & Co., Inc. Method of preparing inhibitors of phosphodiesterase-4
AR042194A1 (es) * 2002-11-22 2005-06-15 Merck & Co Inc Metodo para preparar inhibidores de fosfodiesterasa - 4
UA79518C2 (en) * 2002-11-22 2007-06-25 Merck & Co Inc Process for preparation of phosphodiesterase-4 inhibitors
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
US20050232983A1 (en) * 2004-04-14 2005-10-20 Indevus Pharmaceuticals, Inc. Transdermal patch
EP1904046A4 (en) * 2005-07-06 2008-10-01 Sepracor Inc COMBINATIONS OF ESZOPICLON AND O-DESMETHYLVENLAFAXINE AND METHOD FOR THE TREATMENT OF MENOPAUSE AND HUMOR FLUCTUATIONS; ANXIETY AND COGNITIVE INTERFERENCE
EP1904066B1 (en) 2005-07-06 2018-05-23 Sunovion Pharmaceuticals Inc. COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, for treating MENOPAUSE, perimenopause AND COGNITIVE DISORDERS
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
US7985756B2 (en) 2005-10-21 2011-07-26 Braincells Inc. Modulation of neurogenesis by PDE inhibition
EP2314289A1 (en) 2005-10-31 2011-04-27 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
US20080305171A1 (en) * 2007-06-07 2008-12-11 Kristin Anne Arnold Pyrrolopyrazine, formulations, methods of manufacture, and methods of use there
CN100569775C (zh) * 2007-12-19 2009-12-16 齐鲁天和惠世制药有限公司 佐匹克隆的晶型转换的方法
AU2010208240A1 (en) 2009-01-30 2011-09-22 Sunovion Pharmaceuticals Inc Coated tablets of 6-(5-chloro-2-pyridyl) -5-[ (4-methyl-1-piperazinyl) carbonyloxy]-7-oxo-6, 7-dihydro-5H-pyrrol o [3,4-b] pyrazine and methods for measuring effectiveness of coating
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN110678497B (zh) * 2017-05-25 2022-09-16 信越化学工业株式会社 含有氟聚醚基的聚合物改性有机硅化合物、表面处理剂和物品
CN108129476A (zh) * 2017-11-27 2018-06-08 华中农业大学 一种杂环内酰胺衍生物及其用于作物病原菌杀菌剂的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1312427A (fr) * 1961-04-12 1962-12-21 Science Union Et Compagnie Soc Nouveaux dérivés de la pipérazine et leurs préparations
FR2101081B1 (OSRAM) * 1970-08-19 1974-01-11 Rhone Poulenc Sa
BE790408A (fr) * 1971-10-22 1973-04-20 Rhone Poulenc Sa Nouveaux derives de la pyrrolo (3,4-b) pyridine, leur preparation et les compositions medicinales qui les
OA04285A (fr) * 1972-01-07 1979-12-31 Rhone Poulenc Sa Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation.
BE793851A (fr) * 1972-01-10 1973-07-10 Rhone Poulenc Sa Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent
AR207555A1 (es) * 1972-12-04 1976-10-15 Procedimiento para preparar aril-6-piperazinocarboniloxi-5 oxo-7 tetrahidro-2,3,6,7 ditiino(1,4)(2,3-c)pirroles
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.

Also Published As

Publication number Publication date
HK19380A (en) 1980-04-18
AU8633175A (en) 1977-05-12
ATA401977A (de) 1977-10-15
YU192182A (en) 1983-01-21
CS231957B2 (en) 1985-01-16
SU673173A3 (ru) 1979-07-05
NO753713L (OSRAM) 1976-05-10
GB1468497A (en) 1977-03-30
PL101248B1 (pl) 1978-12-30
IL48423A0 (en) 1976-01-30
OA05162A (fr) 1981-01-31
CH609057A5 (OSRAM) 1979-02-15
CS231958B2 (en) 1985-01-16
DK141098B (da) 1980-01-14
CS751075A2 (en) 1984-01-16
YU39583B (en) 1985-03-20
NL7512732A (nl) 1976-05-11
CS598377A2 (en) 1984-01-16
CA1057755A (fr) 1979-07-03
YU281575A (en) 1983-01-21
DK499275A (OSRAM) 1976-05-08
JPS5170776A (OSRAM) 1976-06-18
SE7512477L (sv) 1976-05-10
SU604496A3 (ru) 1978-04-25
BE835325A (fr) 1976-05-06
DK141098C (OSRAM) 1980-07-07
NO143576C (no) 1981-03-11
JPS5498790A (en) 1979-08-03
AT343666B (de) 1978-06-12
AR208414A1 (es) 1976-12-27
NL177405B (nl) 1985-04-16
IL48423A (en) 1979-03-12
FI60707B (fi) 1981-11-30
DE2550111A1 (de) 1976-05-13
US4220646A (en) 1980-09-02
FI753127A7 (OSRAM) 1976-05-08
HU173108B (hu) 1979-02-28
SE407063B (sv) 1979-03-12
IE41928B1 (en) 1980-04-23
CY1045A (en) 1980-08-01
YU40087B (en) 1985-06-30
AT343123B (de) 1978-05-10
JPS558508B2 (OSRAM) 1980-03-04
ATA848675A (de) 1977-09-15
LU73738A1 (OSRAM) 1976-09-06
NL177405C (nl) 1985-09-16
NO143576B (no) 1980-12-01
DE2550111C2 (de) 1983-09-15
IE41928L (en) 1976-05-07
FI60707C (fi) 1982-03-10
AU503200B2 (en) 1979-08-30
AR208800A1 (es) 1977-02-28
DD122684A5 (OSRAM) 1976-10-20

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