JPH0659218B2 - Ｄｎａ導入ベクタ− - Google Patents

Ｄｎａ導入ベクタ−

Info

Publication number
JPH0659218B2
JPH0659218B2 JP53063756A JP6375678A JPH0659218B2 JP H0659218 B2 JPH0659218 B2 JP H0659218B2 JP 53063756 A JP53063756 A JP 53063756A JP 6375678 A JP6375678 A JP 6375678A JP H0659218 B2 JPH0659218 B2 JP H0659218B2
Authority
JP
Japan
Prior art keywords
dna
plasmid
cells
cdna
mrna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP53063756A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5449387A (en
Inventor
ウイリアム・ジエイ・ラツタ−
ハワ−ド・マイクル・グツドマン
アクセル・ウルリツチ
ジヨン・シヤイン
ジヨン・ミツチエル・チヤ−グウイン
レイモンド・ルイス・ピクテツト
ピ−タ−・ホ−スト・シ−バ−グ
Original Assignee
ザ レジエンツ オブ ザ ユニバ−シイテイ オブ カリフオルニア
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05897710 external-priority patent/US4363877B1/en
Priority claimed from US05/898,887 external-priority patent/US4264731A/en
Application filed by ザ レジエンツ オブ ザ ユニバ−シイテイ オブ カリフオルニア filed Critical ザ レジエンツ オブ ザ ユニバ−シイテイ オブ カリフオルニア
Publication of JPS5449387A publication Critical patent/JPS5449387A/ja
Publication of JPH0659218B2 publication Critical patent/JPH0659218B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57518—Placental lactogen; Chorionic somatomammotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP53063756A 1977-05-27 1978-05-27 Ｄｎａ導入ベクタ− Expired - Lifetime JPH0659218B2 (ja)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US80134377A 1977-05-27 1977-05-27
US80502377A 1977-06-09 1977-06-09
US89770978A 1978-04-19 1978-04-19
US05897710 US4363877B1 (en) 1977-09-23 1978-04-19 Recombinant dna transfer vectors
US05/898,887 US4264731A (en) 1977-05-27 1978-04-21 DNA Joining method
US89900278A 1978-04-26 1978-04-26
US89900378A 1978-04-26 1978-04-26
US897709 1978-04-26
US801343 1978-04-26
US898887 1978-04-26
US899002 1978-04-26
US805023 1978-04-26
US897710 1978-04-26
US899003 1986-08-22

Publications (2)

Publication Number Publication Date
JPS5449387A JPS5449387A (en) 1979-04-18
JPH0659218B2 true JPH0659218B2 (ja) 1994-08-10

Family

ID=27569921

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53063756A Expired - Lifetime JPH0659218B2 (ja) 1977-05-27 1978-05-27 Ｄｎａ導入ベクタ−

Country Status (21)

Country Link
JP (1) JPH0659218B2 (https=)
AR (1) AR225404A1 (https=)
AU (1) AU521903B2 (https=)
BE (1) BE867424A (https=)
BG (1) BG40319A3 (https=)
CH (1) CH642680A5 (https=)
DD (1) DD145927A5 (https=)
DE (2) DE2858357C2 (https=)
DK (2) DK233278A (https=)
FI (1) FI64640C (https=)
FR (1) FR2392033B1 (https=)
GB (1) GB1565190A (https=)
GR (1) GR73552B (https=)
IL (1) IL54790A (https=)
IT (1) IT1094934B (https=)
LU (1) LU79714A1 (https=)
NL (1) NL7805591A (https=)
NZ (1) NZ187300A (https=)
PL (1) PL140200B1 (https=)
PT (1) PT68082B (https=)
SE (4) SE451461B (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU527165B2 (en) * 1977-02-08 1983-02-17 Genentech Inc. Method and means for microbial polypeptide expression; synthetic DNA and process therefor
ZA782933B (en) * 1977-09-23 1979-05-30 Univ California Purification of nucleotide sequences suitable for expression in bacteria
FI792481A7 (fi) * 1978-08-11 1981-01-01 The Regents Of The Univ Of Enkaroyyttisen proteiinin synteesi mikro-organismia käyttäen.
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
JPS55150883A (en) * 1979-05-11 1980-11-25 Nakano Vinegar Co Ltd Method of storing "mozuku"
GR68404B (https=) * 1979-06-01 1981-12-29 Univ California
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (https=) * 1979-09-12 1982-09-03 Univ California
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
IL61982A (en) * 1980-02-15 1984-01-31 Cpc International Inc Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
CA1202581A (en) * 1980-03-27 1986-04-01 Saran A. Narang Adaptor molecules for dna and their application to synthesis of gene-derived products
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
ATE22327T1 (de) * 1980-12-12 1986-10-15 Unilever Nv Dna-sequenzen fuer verschiedene allele formen des reifen thaumatins, diese sequenzen enthaltende rekombinante plasmide, verfahren zur herstellung dieser plasmide, diese rekombinante plasmide enthaltende bakterielle kulturen und verfahren zur herstellung von reifen thaumatin.
ATE76901T1 (de) * 1980-12-12 1992-06-15 Unilever Nv Strukturgene, die fuer die verschiedenen allelischen und reifungsformen von praeprothaumatin und deren mutanten kodieren, diese strukturgene enthaltende klonierungsvektoren und deren expression in mikrobiellen wirtzellen.
US4695543A (en) * 1982-03-23 1987-09-22 Bristol-Myers Company Alpha Interferon GX-1
US4748233A (en) * 1982-03-23 1988-05-31 Bristol-Myers Company Alpha-interferon Gx-1
CA1224432A (en) * 1982-08-17 1987-07-21 Gary N. Buell Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
US5474980A (en) * 1984-10-04 1995-12-12 Monsanto Company Prolonged release of biologically active somatotropins
US5411951A (en) * 1984-10-04 1995-05-02 Monsanto Company Prolonged release of biologically active somatotropin
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
DE4034702A1 (de) * 1990-10-31 1992-05-07 Siemens Ag Verfahren und vorrichtung zur pruefung der aktiven werkzeuge von gesenkbiegemaschinen, insbesondere von biegestempeln

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Ｃｅｌｌ，６（１９７５−１０）Ｐ．２３１〜２４４
Ｃｅｌｌ，８（１９７６−６）Ｐ．１６３〜１８２
ＮａｃｌｅｉｃＡｃｉｄｓＲｃｓｅａｒｃｈ，３〔８〕（１９７６−８）Ｐ．１９６１〜１９７１
Ｒｒｏｃ，ＮａｔｈＡｃａｄＳｃｉ，Ｕ．Ｓ．Ａ．７３〔９〕（１９７６−９）Ｐ．３１４６〜３１５０

Also Published As

Publication number Publication date
GR73552B (https=) 1984-03-14
IL54790A0 (en) 1978-07-31
FR2392033B1 (fr) 1985-09-13
GB1565190A (en) 1980-04-16
PT68082B (en) 1980-02-20
DK791A (da) 1991-01-04
FR2392033A1 (fr) 1978-12-22
SE8305327D0 (sv) 1983-09-29
DK233278A (da) 1978-11-28
DE2822568A1 (de) 1978-12-14
CH642680A5 (en) 1984-04-30
FI64640B (fi) 1983-08-31
DE2822568C2 (https=) 1989-08-31
SE7806086L (sv) 1978-11-28
DK791D0 (da) 1991-01-04
PT68082A (en) 1978-06-01
JPS5449387A (en) 1979-04-18
SE455794B (sv) 1988-08-08
AU3648878A (en) 1979-11-29
SE8305328L (sv) 1983-09-29
SE8305328D0 (sv) 1983-09-29
IL54790A (en) 1983-07-31
BG40319A3 (bg) 1986-11-14
BE867424A (fr) 1978-09-18
SE451461B (sv) 1987-10-12
LU79714A1 (fr) 1978-11-06
DE2858357C2 (https=) 1990-03-15
FI781675A7 (fi) 1978-11-28
PL140200B1 (en) 1987-04-30
NL7805591A (nl) 1978-11-29
SE8305329D0 (sv) 1983-09-29
IT1094934B (it) 1985-08-10
AR225404A1 (es) 1982-03-31
AU521903B2 (en) 1982-05-06
DD145927A5 (de) 1981-01-14
NZ187300A (en) 1982-08-17
SE8305327L (sv) 1983-09-29
PL207176A1 (pl) 1979-03-26
SE8305329L (sv) 1983-09-29
IT7823930A0 (it) 1978-05-29
FI64640C (fi) 1983-12-12

Similar Documents

Publication Publication Date Title
JPH0659218B2 (ja) Ｄｎａ導入ベクタ−
US4440859A (en) Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms
JP2766781B2 (ja) ウシ成長ホルモンを生産し得る微生物
KR930001117B1 (ko) Dna 재조합 기술에 의한 폴리펩티드 제조방법
US4652525A (en) Recombinant bacterial plasmids containing the coding sequences of insulin genes
CS250655B2 (en) Method of microorganisme's viable culture's cultivation with means content for asexual regeneration
EP0020147A1 (en) A DNA transfer vector for human pre-growth hormone, a microorganism transformed thereby, and a method of cloning therefor
JP2637393B2 (ja) プロインシュリンおよびプレプロインシュリン産生暗号を有するヒト遺伝子
EP0067026A1 (en) Process for cloning bovine hormone gene, and plasmids and plasmid hosts for use therein
JPH05260979A (ja) Ｄ−リボースの製造法
CZ2017537A3 (cs) Kmen bakterie Clostridium histolitycum, kolagenáza připravená s použitím tohoto kmene a její použití
JPH02190193A (ja) アミド化ペプチドの製造方法
JPH04252180A (ja) グルコース−６−リン酸デヒドロゲナーゼ、ｄｎａ、微生物、ｄｎａの取得法、グルコース−６−リン酸デヒドロゲナーゼの取得法並びに試料溶液中のグルコース−６−リン酸含量を酵素測定する方法及び試薬
NL8100210A (nl) Microbiologisch verkregen polypeptide met de aminozuurvolgorde van het proinsuline van primaten, dna en plasmiden, die deze volgorde coderen, microoerganismen die deze genetische informatie bevatten en het maken daarvan.
US5045471A (en) Cloned DNA for P450scc and expression thereof
FI74732B (fi) Dna-oeverfoeringsvektor, vilken innehaoller en nukleotidsekvens som kodar foer tillvaexthormon.
FI65446C (fi) Foerfarande foer framstaellning av en bakterie som innehaolleren foer insulin kodande nukleotidsekvens
FI65447C (fi) Foerfarande foer framstaellning av en bakterie som innehaolleren foer tillvaexthormon kodande nukleotidsekvens
KR840001441B1 (ko) 고등생물의 특정 단백질에 대한 뉴클레오티드 배열을 함유하는 dna전달 매개체의 제조방법
FI75185C (fi) Dna-oeverfoeringsvektor, vilken innehaoller en foer insulin kodande nukleotidsekvens.
CA1156166A (en) Recombinant bacterial plasmids containing the coding sequences of insulin genes
JPS61502799A (ja) 組換えｄｎａ分子、形質転換された微生物、並びにペニシリンｖアミダ−ゼの製造方法
SU1205777A3 (ru) Способ получени вектора,имеющего нуклеотидную последовательность,кодирующую протеин
JP2632680B2 (ja) ブリ成長ホルモン構造遺伝子増幅プラスミド
HU193866B (en) Process for preparing plasmid and e.coli bakterium comprising dna sequence and coding humane growth hormone