AU527165B2 - Method and means for microbial polypeptide expression; synthetic DNA and process therefor - Google Patents

Method and means for microbial polypeptide expression; synthetic DNA and process therefor

Info

Publication number
AU527165B2
AU527165B2 AU41361/78A AU4136178A AU527165B2 AU 527165 B2 AU527165 B2 AU 527165B2 AU 41361/78 A AU41361/78 A AU 41361/78A AU 4136178 A AU4136178 A AU 4136178A AU 527165 B2 AU527165 B2 AU 527165B2
Authority
AU
Australia
Prior art keywords
synthetic dna
polypeptide expression
process therefor
microbial polypeptide
microbial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU41361/78A
Other versions
AU4136178A (en
Inventor
Keiichi Itakura
Arthur Dale Riggs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of AU4136178A publication Critical patent/AU4136178A/en
Application granted granted Critical
Publication of AU527165B2 publication Critical patent/AU527165B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU41361/78A 1977-02-08 1978-11-06 Method and means for microbial polypeptide expression; synthetic DNA and process therefor Expired AU527165B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US849691 1977-02-08
US84969277A 1977-11-08 1977-11-08
US84969177A 1977-11-08 1977-11-08
US84959177A 1977-11-08 1977-11-08
US849692 1977-11-08
US849591 1977-11-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU74484/81A Division AU546092B2 (en) 1977-02-08 1981-08-24 Method and means for microbial polypeptide expression

Publications (2)

Publication Number Publication Date
AU4136178A AU4136178A (en) 1979-05-17
AU527165B2 true AU527165B2 (en) 1983-02-17

Family

ID=27420338

Family Applications (2)

Application Number Title Priority Date Filing Date
AU41361/78A Expired AU527165B2 (en) 1977-02-08 1978-11-06 Method and means for microbial polypeptide expression; synthetic DNA and process therefor
AU74484/81A Expired AU546092B2 (en) 1977-02-08 1981-08-24 Method and means for microbial polypeptide expression

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU74484/81A Expired AU546092B2 (en) 1977-02-08 1981-08-24 Method and means for microbial polypeptide expression

Country Status (7)

Country Link
AU (2) AU527165B2 (en)
BR (1) BR7807290A (en)
FR (3) FR2422717B1 (en)
LU (1) LU80489A1 (en)
OA (1) OA06002A (en)
RO (1) RO80052B (en)
ZM (1) ZM9578A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU542264B2 (en) * 1979-06-01 1985-02-14 G.D. Searle & Co. Plasmid vectors
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
US4645828A (en) * 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
AU580064B2 (en) * 1984-06-04 1988-12-22 Lubrizol Genetics Inc. Nitrogen fixation regulator genes
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
US4987070A (en) * 1987-03-04 1991-01-22 Suntory Limited Use of a 97 amino acid leader sequence from the E. coli B-galactosidase gene for the production of hanp and hptc as fusion proteins

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4136078A (en) * 1977-11-08 1979-05-17 Genentech Inc Triester process for the synthesis of oligonucleotides
AU3648878A (en) * 1977-05-27 1979-11-29 Regents Of The University Of California, The Dna transfer vector
AU3648978A (en) * 1977-09-23 1979-11-29 Regents Of The University Of California, The Purification of nucleotide sequences

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
FR2422685A1 (en) * 1978-04-14 1979-11-09 Pasteur Institut VECTORS, DERIVED FROM LAMBDA BACTERIOPHAGUS, ALLOWING THE INSERTION AND EXPRESSION OF A GENE, PROCARYOTE OR EUKARYOTE, UNDER THE CONTROL OF THE PROMOTER AND THE OPERATOR OF THE LACTOSE OPERON OF ESCHERICHIA COLI BACTERIA
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
FR2428075A1 (en) * 1978-06-08 1980-01-04 Pasteur Institut PROCESS FOR THE PRODUCTION OF PROTEINS BY EXPRESSION OF THE CORRESPONDING GENES IN BACTERIA AND VECTORS LIKELY TO BE USED IN SUCH METHODS
FI792481A (en) * 1978-08-11 1980-02-12 Univ California SYNTHESIS OF ENCAROYTIC PROTEIN GENOM ANVAENDNING AV MICRO-ORGANISM
GB2033905B (en) * 1978-08-21 1982-10-13 Upjohn Co Bacterial preparation of proteins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3648878A (en) * 1977-05-27 1979-11-29 Regents Of The University Of California, The Dna transfer vector
AU3648978A (en) * 1977-09-23 1979-11-29 Regents Of The University Of California, The Purification of nucleotide sequences
AU4136078A (en) * 1977-11-08 1979-05-17 Genentech Inc Triester process for the synthesis of oligonucleotides

Also Published As

Publication number Publication date
FR2422717A1 (en) 1979-11-09
RO80052A (en) 1985-03-15
AU546092B2 (en) 1985-08-15
FR2422719A1 (en) 1979-11-09
FR2422717B1 (en) 1985-12-06
ZM9578A1 (en) 1980-03-21
BR7807290A (en) 1979-06-12
OA06002A (en) 1981-06-30
AU4136178A (en) 1979-05-17
RO80052B (en) 1985-03-30
FR2422719B1 (en) 1984-12-28
LU80489A1 (en) 1979-03-22
FR2422718B1 (en) 1984-05-18
AU7448481A (en) 1982-01-14
FR2422718A1 (en) 1979-11-09

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