FR2392033A1 - Vecteur de transfert d'adn recombinant et microorganisme contenant un gene provenant d'un organisme superieur - Google Patents

Vecteur de transfert d'adn recombinant et microorganisme contenant un gene provenant d'un organisme superieur

Info

Publication number
FR2392033A1
FR2392033A1 FR7815596A FR7815596A FR2392033A1 FR 2392033 A1 FR2392033 A1 FR 2392033A1 FR 7815596 A FR7815596 A FR 7815596A FR 7815596 A FR7815596 A FR 7815596A FR 2392033 A1 FR2392033 A1 FR 2392033A1
Authority
FR
France
Prior art keywords
gene
recombinant dna
higher organism
transfer vector
dna transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7815596A
Other languages
English (en)
Other versions
FR2392033B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05897710 external-priority patent/US4363877B1/en
Priority claimed from US05/898,887 external-priority patent/US4264731A/en
Application filed by University of California filed Critical University of California
Publication of FR2392033A1 publication Critical patent/FR2392033A1/fr
Application granted granted Critical
Publication of FR2392033B1 publication Critical patent/FR2392033B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57518—Placental lactogen; Chorionic somatomammotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne un procédé permettant d'isoler une séquence de nucléotides codant pour une protéine spécifique, à partir d'un organisme supérieur, la synthèse d'ADN ayant cette séquence de nucléotides particulière et le transfert de l'information génétique y contenue à un microorganisme où elle peut être répliquée indéfiniment. Le procédé est applicable à l'isolement et à la purification du gene de l'insuline humaine, aussi bien que du gène de l'hormone de croissance humaine et à leur transfert et réplication dans un microorganisme.
FR7815596A 1977-05-27 1978-05-25 Vecteur de transfert d'adn recombinant et microorganisme contenant un gene provenant d'un organisme superieur Expired FR2392033B1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US80134377A 1977-05-27 1977-05-27
US80502377A 1977-06-09 1977-06-09
US89770978A 1978-04-19 1978-04-19
US05897710 US4363877B1 (en) 1977-09-23 1978-04-19 Recombinant dna transfer vectors
US05/898,887 US4264731A (en) 1977-05-27 1978-04-21 DNA Joining method
US89900378A 1978-04-26 1978-04-26
US89900278A 1978-04-26 1978-04-26

Publications (2)

Publication Number Publication Date
FR2392033A1 true FR2392033A1 (fr) 1978-12-22
FR2392033B1 FR2392033B1 (fr) 1985-09-13

Family

ID=27569921

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7815596A Expired FR2392033B1 (fr) 1977-05-27 1978-05-25 Vecteur de transfert d'adn recombinant et microorganisme contenant un gene provenant d'un organisme superieur

Country Status (21)

Country Link
JP (1) JPH0659218B2 (fr)
AR (1) AR225404A1 (fr)
AU (1) AU521903B2 (fr)
BE (1) BE867424A (fr)
BG (1) BG40319A3 (fr)
CH (1) CH642680A5 (fr)
DD (1) DD145927A5 (fr)
DE (2) DE2822568A1 (fr)
DK (2) DK233278A (fr)
FI (1) FI64640C (fr)
FR (1) FR2392033B1 (fr)
GB (1) GB1565190A (fr)
GR (1) GR73552B (fr)
IL (1) IL54790A (fr)
IT (1) IT1094934B (fr)
LU (1) LU79714A1 (fr)
NL (1) NL7805591A (fr)
NZ (1) NZ187300A (fr)
PL (1) PL140200B1 (fr)
PT (1) PT68082B (fr)
SE (4) SE451461B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2404013A1 (fr) * 1977-09-23 1979-04-20 Univ California Procede de purification de sequences de nucleotides, en vue de leur replication dans les bacteries
FR2464997A1 (fr) * 1979-09-12 1981-03-20 Univ California Genes de la proinsuline humaine et de pre-proinsuline humaine, leur procede de preparation et leurs applications
EP0040466A2 (fr) * 1980-03-27 1981-11-25 Canadian Patents and Development Limited Molécules adaptatrices pour ADN et leur application à la synthèse de produit dérivés de gènes

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422717B1 (fr) * 1977-11-08 1985-12-06 Genentech Inc Procede permettant l'expression microbienne de polypeptides et moyens appropries
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
JPS55150883A (en) * 1979-05-11 1980-11-25 Nakano Vinegar Co Ltd Method of storing "mozuku"
ZA802992B (en) * 1979-06-01 1981-10-28 Univ California Human pre-growth hormone
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
IL58765A (en) * 1979-11-21 1986-09-30 Yeda Res & Dev Process for the production of essentially pure messenger rna of human fibroblast interferon and process for the production of interferon beta
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
IL61982A (en) * 1980-02-15 1984-01-31 Cpc International Inc Genetically engineered microorganisms for massive production of amyloytic enzymes and process for preparing same using the corresponding recombinant dnas containing amylase coding genes
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
DE3177281T2 (de) * 1980-12-12 1992-12-10 Unilever Nv Strukturgene, die fuer die verschiedenen allelischen und reifungsformen von praeprothaumatin und deren mutanten kodieren, diese strukturgene enthaltende klonierungsvektoren und deren expression in mikrobiellen wirtzellen.
IE52417B1 (en) * 1980-12-12 1987-10-28 Unilever Plc Dna sequences encoding various allelic forms of mature thaumatin,recombinant plasmids comprising said dnas and a process for their preparation,bacterial cultures comprising said recombinant plasmids,and method for producing mature thaumatin
US4748233A (en) * 1982-03-23 1988-05-31 Bristol-Myers Company Alpha-interferon Gx-1
US4695543A (en) * 1982-03-23 1987-09-22 Bristol-Myers Company Alpha Interferon GX-1
EP0103395A3 (fr) * 1982-08-17 1985-05-22 Biogen N.V. Séquences d'ADN, molécules recombinantes d'ADN et procédés pour la production de peptides du genre de l'hormone de croissance bovine, avec rendement élevé
US5474980A (en) * 1984-10-04 1995-12-12 Monsanto Company Prolonged release of biologically active somatotropins
US5411951A (en) * 1984-10-04 1995-05-02 Monsanto Company Prolonged release of biologically active somatotropin
DK257988D0 (da) * 1988-05-11 1988-05-11 Novo Industri As Nye peptider
DE4034702A1 (de) * 1990-10-31 1992-05-07 Siemens Ag Verfahren und vorrichtung zur pruefung der aktiven werkzeuge von gesenkbiegemaschinen, insbesondere von biegestempeln

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1977 *
EXBK/77 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2404013A1 (fr) * 1977-09-23 1979-04-20 Univ California Procede de purification de sequences de nucleotides, en vue de leur replication dans les bacteries
FR2464997A1 (fr) * 1979-09-12 1981-03-20 Univ California Genes de la proinsuline humaine et de pre-proinsuline humaine, leur procede de preparation et leurs applications
EP0040466A2 (fr) * 1980-03-27 1981-11-25 Canadian Patents and Development Limited Molécules adaptatrices pour ADN et leur application à la synthèse de produit dérivés de gènes
EP0040466A3 (en) * 1980-03-27 1982-12-08 Canadian Patents And Development Limited Adaptor molecules for dna and their application to synthesis of gene-derived products

Also Published As

Publication number Publication date
SE455794B (sv) 1988-08-08
LU79714A1 (fr) 1978-11-06
DE2822568A1 (de) 1978-12-14
AU521903B2 (en) 1982-05-06
BG40319A3 (en) 1986-11-14
JPH0659218B2 (ja) 1994-08-10
DK791D0 (da) 1991-01-04
SE7806086L (sv) 1978-11-28
GR73552B (fr) 1984-03-14
CH642680A5 (en) 1984-04-30
DE2822568C2 (fr) 1989-08-31
DE2858357C2 (fr) 1990-03-15
NL7805591A (nl) 1978-11-29
IL54790A (en) 1983-07-31
NZ187300A (en) 1982-08-17
SE8305327L (sv) 1983-09-29
DK233278A (da) 1978-11-28
JPS5449387A (en) 1979-04-18
SE8305327D0 (sv) 1983-09-29
BE867424A (fr) 1978-09-18
SE8305328D0 (sv) 1983-09-29
PL140200B1 (en) 1987-04-30
PL207176A1 (pl) 1979-03-26
SE8305328L (sv) 1983-09-29
AR225404A1 (es) 1982-03-31
FI64640B (fi) 1983-08-31
IL54790A0 (en) 1978-07-31
IT1094934B (it) 1985-08-10
FI64640C (fi) 1983-12-12
GB1565190A (en) 1980-04-16
PT68082A (en) 1978-06-01
SE8305329L (sv) 1983-09-29
SE451461B (sv) 1987-10-12
DK791A (da) 1991-01-04
PT68082B (en) 1980-02-20
AU3648878A (en) 1979-11-29
DD145927A5 (de) 1981-01-14
FI781675A (fi) 1978-11-28
FR2392033B1 (fr) 1985-09-13
IT7823930A0 (it) 1978-05-29
SE8305329D0 (sv) 1983-09-29

Similar Documents

Publication Publication Date Title
FR2392033A1 (fr) Vecteur de transfert d'adn recombinant et microorganisme contenant un gene provenant d'un organisme superieur
US4440859A (en) Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms
Brown Gene expression in eukaryotes
MARKERT Epigenetic Control of Specific Protein Synthesis in Differentiating Cells
US4652525A (en) Recombinant bacterial plasmids containing the coding sequences of insulin genes
EP0759170A4 (fr) Methodes d'utilisation de proteines fluorescentes vertes
EP0020147B1 (fr) Vecteur de transfert d'ADN pour la prohormone de croissance humaine, microorganisme transformé par celui-ci et procédé de clonage à cet effet
HUP0004484A2 (hu) Deszaturázgének és alkalmazásaik
DE3586189T2 (de) Menge und verfahren zur herstellung rekombinierter erzeugnisse in grosser ausbeute.
Panyim et al. Constant electrophoretic mobility of the cysteine-containing histone in plants and animals
ATE42114T1 (de) Mikrobiologisch hergestelltes interferon alpha2(arg), dna-sequenz, die fuer dieses interferon codiert, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung.
DE3410437A1 (de) Verfahren zur herstellung von proteinen
Miller Recombinant DNA and the pediatrician
JPS60500043A (ja) 原核細胞又は真核細胞中で合成される融合蛋白質から成熟蛋白質を作る方法
Paterson et al. Molecular basis of altered enzyme specificities in a family of mutant amidases from Pseudomonas aeruginosa
Vogel et al. Mutation and molecular evolution
Marx How peptide hormones get ready for work: researchers seem to have found the enzymes that clip peptide hormones and neurotransmitters out of their precursors
Sabatini et al. Biochemical methods for analysis of kinetoplastid RNA editing
Baker et al. The Technological Uses and Methodology of Recombinant DNA
CA1156166A (fr) Plasmides bacteriens recombinants contenant les codes de genes pour la production d'insuline
Pragai et al. Processing of bacteriophage T4 tRNAs: An RNAase III− strain contains a precursor for tRNAGln and tRNALeu
Ockey The chemistry of the eukaryote chromosome
PHYSARUM MOTILITY IS A FUNDAMENTAL BIOLOGICAL PROPERTY
Arthur et al. High level expression of interleukin-1β in a recombinant Escherichia coli strain for use in a controlled bioreactor
FI75185B (fi) Dna-oeverfoeringsvektor, vilken innehaoller en foer insulin kodande nukleotidsekvens.