FR2422717B1 - Procede permettant l'expression microbienne de polypeptides et moyens appropries - Google Patents

Procede permettant l'expression microbienne de polypeptides et moyens appropries

Info

Publication number
FR2422717B1
FR2422717B1 FR7831350A FR7831350A FR2422717B1 FR 2422717 B1 FR2422717 B1 FR 2422717B1 FR 7831350 A FR7831350 A FR 7831350A FR 7831350 A FR7831350 A FR 7831350A FR 2422717 B1 FR2422717 B1 FR 2422717B1
Authority
FR
France
Prior art keywords
polypeptides
appropriate means
microbial expression
microbial
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7831350A
Other languages
English (en)
Other versions
FR2422717A1 (fr
Inventor
Dale Riggs
Keiichi Itakura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of FR2422717A1 publication Critical patent/FR2422717A1/fr
Application granted granted Critical
Publication of FR2422717B1 publication Critical patent/FR2422717B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FR7831350A 1977-11-08 1978-11-06 Procede permettant l'expression microbienne de polypeptides et moyens appropries Expired FR2422717B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84969177A 1977-11-08 1977-11-08
US84969277A 1977-11-08 1977-11-08
US84959177A 1977-11-08 1977-11-08

Publications (2)

Publication Number Publication Date
FR2422717A1 FR2422717A1 (fr) 1979-11-09
FR2422717B1 true FR2422717B1 (fr) 1985-12-06

Family

ID=27420338

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7831350A Expired FR2422717B1 (fr) 1977-11-08 1978-11-06 Procede permettant l'expression microbienne de polypeptides et moyens appropries
FR7916726A Granted FR2422719A1 (fr) 1977-11-08 1979-06-28 Procede permettant l'expression microbienne de polypeptides et moyens appropries
FR7916725A Granted FR2422718A1 (fr) 1977-11-08 1979-06-28 Procede permettant l'expression mocrobienne de polypeptides et moyens appropries

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR7916726A Granted FR2422719A1 (fr) 1977-11-08 1979-06-28 Procede permettant l'expression microbienne de polypeptides et moyens appropries
FR7916725A Granted FR2422718A1 (fr) 1977-11-08 1979-06-28 Procede permettant l'expression mocrobienne de polypeptides et moyens appropries

Country Status (7)

Country Link
AU (2) AU527165B2 (fr)
BR (1) BR7807290A (fr)
FR (3) FR2422717B1 (fr)
LU (1) LU80489A1 (fr)
OA (1) OA06002A (fr)
RO (1) RO80052B (fr)
ZM (1) ZM9578A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU542264B2 (en) * 1979-06-01 1985-02-14 G.D. Searle & Co. Plasmid vectors
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
US4645828A (en) * 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
AU580064B2 (en) * 1984-06-04 1988-12-22 Lubrizol Genetics Inc. Nitrogen fixation regulator genes
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
US4987070A (en) * 1987-03-04 1991-01-22 Suntory Limited Use of a 97 amino acid leader sequence from the E. coli B-galactosidase gene for the production of hanp and hptc as fusion proteins

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
NZ187300A (en) * 1977-05-27 1982-08-17 Univ California Dna transfer vector and micro-organism modified to contain a nucleotide sequence equivalent to the gene of a higher organism
ZA782933B (en) * 1977-09-23 1979-05-30 Univ California Purification of nucleotide sequences suitable for expression in bacteria
BR7807288A (pt) * 1977-11-08 1979-06-12 Genentech Inc Processo para sintese de polinucleotidos
FR2422685A1 (fr) * 1978-04-14 1979-11-09 Pasteur Institut Vecteurs, derives du bacteriophage lambda, permettant l'insertion et l'expression d'un gene, procaryote ou eucaryote, sous le controle du promoteur et de l'operateur de l'operon lactose de la bacterie escherichia coli
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
FR2428075A1 (fr) * 1978-06-08 1980-01-04 Pasteur Institut Procede de production de proteines par expression des genes correspondants dans des bacteries et vecteurs susceptibles d'etre mis en oeuvre dans de tels procedes
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
GB2033905B (en) * 1978-08-21 1982-10-13 Upjohn Co Bacterial preparation of proteins

Also Published As

Publication number Publication date
AU7448481A (en) 1982-01-14
ZM9578A1 (en) 1980-03-21
FR2422717A1 (fr) 1979-11-09
RO80052B (ro) 1985-03-30
AU527165B2 (en) 1983-02-17
FR2422719B1 (fr) 1984-12-28
AU546092B2 (en) 1985-08-15
BR7807290A (pt) 1979-06-12
OA06002A (fr) 1981-06-30
FR2422718B1 (fr) 1984-05-18
LU80489A1 (fr) 1979-03-22
AU4136178A (en) 1979-05-17
RO80052A (fr) 1985-03-15
FR2422719A1 (fr) 1979-11-09
FR2422718A1 (fr) 1979-11-09

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Legal Events

Date Code Title Description
RT Complete renunciation
ST Notification of lapse