BE871782A - Procede permettant l'expression microbienne de polypeptides et moyens appropries - Google Patents

Procede permettant l'expression microbienne de polypeptides et moyens appropries

Info

Publication number
BE871782A
BE871782A BE1009121A BE1009121A BE871782A BE 871782 A BE871782 A BE 871782A BE 1009121 A BE1009121 A BE 1009121A BE 1009121 A BE1009121 A BE 1009121A BE 871782 A BE871782 A BE 871782A
Authority
BE
Belgium
Prior art keywords
polypeptides
appropriate means
process allowing
microbial expression
microbial
Prior art date
Application number
BE1009121A
Other languages
English (en)
Inventor
K Itakura
A Dale Tiggs
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25306071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE871782(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BE871782A publication Critical patent/BE871782A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BE1009121A 1977-11-08 1978-11-06 Procede permettant l'expression microbienne de polypeptides et moyens appropries BE871782A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84959177A 1977-11-08 1977-11-08

Publications (1)

Publication Number Publication Date
BE871782A true BE871782A (fr) 1979-05-07

Family

ID=25306071

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1009121A BE871782A (fr) 1977-11-08 1978-11-06 Procede permettant l'expression microbienne de polypeptides et moyens appropries

Country Status (28)

Country Link
EP (1) EP0001930B1 (fr)
JP (2) JPS54145289A (fr)
AT (1) AT373280B (fr)
BE (1) BE871782A (fr)
BG (1) BG38166A3 (fr)
CA (2) CA1166983A (fr)
CH (1) CH656640A5 (fr)
DD (1) DD145928A5 (fr)
DE (2) DE2862496D1 (fr)
DK (1) DK493878A (fr)
ES (1) ES474849A1 (fr)
FI (1) FI783366A (fr)
GB (1) GB2008123B (fr)
GR (1) GR72861B (fr)
HK (1) HK87284A (fr)
IE (1) IE47890B1 (fr)
IL (1) IL55890A (fr)
IT (1) IT1100089B (fr)
KE (1) KE3449A (fr)
MY (1) MY8500760A (fr)
NL (1) NL7811041A (fr)
NO (2) NO158880C (fr)
NZ (1) NZ188837A (fr)
PH (1) PH20642A (fr)
PL (1) PL210784A1 (fr)
PT (1) PT68756A (fr)
SE (1) SE7811458L (fr)
ZA (1) ZA786305B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496711A (en) * 1981-01-16 1996-03-05 Genome Therapeutics Corp. Processes for producing pre-prorennin, prorennin and rennin
US6268122B1 (en) 1978-12-22 2001-07-31 Biogen, Inc. Recombinant DNA molecules and their method of production

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
IL60184A (en) * 1979-05-31 1984-05-31 Schering Ag Process for the specific cleavage of protein sequences from proteins
US4342832A (en) 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
DE3001928A1 (de) * 1980-01-19 1981-08-06 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
US6455275B1 (en) 1980-02-25 2002-09-24 The Trustees Of Columbia University In The City Of New York DNA construct for producing proteinaceous materials in eucaryotic cells
CA1200773A (fr) * 1980-02-29 1986-02-18 William J. Rutter Liens d'expression
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
CA1198385A (fr) * 1980-03-17 1985-12-24 Leonard P. Guarente Production optimale de polypeptides
IE57069B1 (en) 1980-04-03 1992-04-22 Biogen Inc Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon
FI83662C (fi) * 1980-07-17 1991-08-12 Scripps Clinic Res Diagnostik antikropp och foerfarande foer dess framstaellning.
IE52122B1 (en) * 1980-08-25 1987-06-24 Univ California Somatostatin or somatostatin precursors
US6692941B1 (en) 1980-08-26 2004-02-17 The Regents Of The University Of California Bovine growth hormone
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
US5137721A (en) * 1981-03-09 1992-08-11 Cetus Corporation Employing strains of E. coli expressing non-indigenous adhesins and toxoids of E. coli
WO1982003088A1 (fr) * 1981-03-09 1982-09-16 Corp Cetus Vaccins
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
JPS5863395A (ja) * 1981-10-13 1983-04-15 Suntory Ltd アルフア・ネオ・エンドルフインの製造法
CA1338705C (fr) * 1981-10-22 1996-11-12 Roy Curtiss Iii Vaccins obtenus a partir de genes, antigenes de genes recombinants
US4532207A (en) * 1982-03-19 1985-07-30 G. D. Searle & Co. Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase
US4880911A (en) * 1982-03-19 1989-11-14 G. D. Searle & Co. Fused polypeptides and methods for their detection
DE3380262D1 (en) * 1982-05-25 1989-08-31 Lilly Co Eli Cloning vectors for expression of exogenous protein
SE8300693L (sv) * 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
NO841276L (no) * 1983-03-31 1984-10-01 Codon Genetic Eng Lab Rekombinant dna-koding for et polypeptid som utviser melkesammenloepende aktivitet
DE3314812A1 (de) * 1983-04-23 1984-10-25 Battelle-Institut E.V., 6000 Frankfurt Mittel zum antigen/antikoerper-nachweis
US4703004A (en) * 1984-01-24 1987-10-27 Immunex Corporation Synthesis of protein with an identification peptide
US5082775A (en) * 1984-05-11 1992-01-21 Berlex Laboratories, Inc. Efficient process for isolating insoluble heterologous protein using non-ionic detergents
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
GB8422238D0 (en) * 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
JPS61264000A (ja) * 1985-03-21 1986-11-21 イミユネツクス　コ−ポレイシヨン 標識ペプチドによるタンパク質の合成
GB8509289D0 (en) * 1985-04-11 1985-05-15 Fujisawa Pharmaceutical Co Production of somatostatin
IL75553A (en) * 1985-06-18 1993-07-08 Yeda Res & Dev Dna sequence coding for a cholinesterase-like peptide, peptides produced by cells containing said dna and antibodies thereto
DE3686365T3 (de) * 1985-06-20 2000-07-27 Fujisawa Pharmaceutical Co., Ltd. Herstellungsverfahren für humanes atriales natriuretisches Polypeptid.
GB8515686D0 (en) * 1985-06-20 1985-07-24 Fujisawa Pharmaceutical Co Production of-human atrial natriuretic polypeptide
FR2599380A1 (fr) * 1986-05-29 1987-12-04 Centre Nat Rech Scient Vecteur d'exportation de proteines chez escherichiacoli, bacteries transformees et procede pour la preparation de proteines
DK175535B1 (da) * 1987-03-04 2004-11-29 Daiichi Suntory Pharma Co Ltd Fremgangsmåde til fremstilling af et fysiologisk aktivt cysteinholdigt peptid
DE3805150A1 (de) * 1987-04-11 1988-10-20 Hoechst Ag Gentechnologisches verfahren zur herstellung von polypeptiden
EP0394409B1 (fr) 1988-09-02 1997-06-11 The Rockefeller University Mediateur inflammatoire derive de macrophages (mip-2)
US5218093A (en) * 1989-03-01 1993-06-08 Allelix Biopharmaceuticals, Inc. EGF variants and pharmaceutical use thereof
JPH0436185A (ja) * 1990-03-28 1992-02-06 Kyowa Hakko Kogyo Co Ltd 融合抗原ポリペプチド
JPH07108232B2 (ja) * 1990-10-09 1995-11-22 エム・ディ・リサーチ株式会社 ペプチド又は蛋白質の製造方法
JPH04315084A (ja) * 1991-04-12 1992-11-06 Kawasaki Heavy Ind Ltd 航空機の対地衝突防止システム
JPH08508640A (ja) 1993-03-10 1996-09-17 スミスクライン・ビーチャム・コーポレイション ヒト脳ホスホジエステラーゼ
US6316004B1 (en) * 1993-06-22 2001-11-13 T. Tikhonenko Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals
US6087128A (en) 1998-02-12 2000-07-11 Ndsu Research Foundation DNA encoding an avian E. coli iss

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0513630A (ja) * 1991-07-05 1993-01-22 Furukawa Electric Co Ltd:The ヒートパイプ式半導体冷却器

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268122B1 (en) 1978-12-22 2001-07-31 Biogen, Inc. Recombinant DNA molecules and their method of production
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
US5496711A (en) * 1981-01-16 1996-03-05 Genome Therapeutics Corp. Processes for producing pre-prorennin, prorennin and rennin

Also Published As

Publication number Publication date
GR72861B (fr) 1983-12-13
NO783723L (no) 1979-05-09
GB2008123B (en) 1982-09-08
IL55890A (en) 1984-01-31
ATA793578A (de) 1983-05-15
JPH0123118B2 (fr) 1989-05-01
MY8500760A (en) 1985-12-31
BG38166A3 (en) 1985-10-15
NZ188837A (en) 1982-09-14
KE3449A (en) 1984-10-05
CA1221324A (fr) 1987-05-05
PH20642A (en) 1987-03-18
JPH0657154B2 (ja) 1994-08-03
SE7811458L (sv) 1979-05-09
NO158880C (no) 1988-11-09
HK87284A (en) 1984-11-16
IT1100089B (it) 1985-09-28
IL55890A0 (en) 1979-01-31
PT68756A (en) 1978-12-01
IE47890B1 (en) 1984-07-11
DD145928A5 (de) 1981-01-14
DE2862496D1 (en) 1989-06-29
IE782192L (en) 1979-05-08
ZA786305B (en) 1979-10-31
NL7811041A (nl) 1979-05-10
IT7829519A0 (it) 1978-11-07
ES474849A1 (es) 1979-12-01
GB2008123A (en) 1979-05-31
DE2848052A1 (de) 1979-05-10
EP0001930A2 (fr) 1979-05-16
PL210784A1 (fr) 1980-02-25
EP0001930B1 (fr) 1989-05-24
JPS54145289A (en) 1979-11-13
CH656640A5 (de) 1986-07-15
CA1166983A (fr) 1984-05-08
NO855217L (no) 1979-05-09
EP0001930A3 (en) 1979-06-13
FI783366A (fi) 1979-05-09
NO158880B (no) 1988-08-01
AT373280B (de) 1984-01-10
DK493878A (da) 1979-05-09
JPS6427480A (en) 1989-01-30

Similar Documents

Publication Publication Date Title
BE871782A (fr) Procede permettant l'expression microbienne de polypeptides et moyens appropries
DK32982A (da) Terapeutisk nyttige tetralinderivater
BE876455A (fr) Procede de therapeutique anxiolytique
FR2443103B1 (fr) Procede d'echantillonnage d'objet
ES498111A0 (es) Aparato de electrolisis
BE865635A (fr) Procede d'osteosynthese
ZA792823B (en) Device for microbiological purposes
BE869294A (fr) Procede de determination de l'amylase
DK230779A (da) Analyseenhed
IT1133663B (it) Apparato inchiostratore
IT7926970A0 (it) Mezzi per l'attivazione e la disattivazione di innesti.
FI792256A (fi) Provroer foer mikrobiologiska undersoekningar
IT1105353B (it) Agenti batterici e procedimento per la loro produzione ed applicazione
ZA763788B (en) Biological process
LU79162A1 (fr) Benzylimidazole derivatives-herbicides et procede d'obtention
GB2031420B (en) N-menylhaloacetamide derivatives and their production and use
LU80489A1 (fr) Procede permettant l'expression microbienne de polypeptides et moyens appropries
BE870410A (fr) Procede d'epuration
FR2320572A1 (fr) Procede et appareil de tirage d'epreuves
BE872294A (fr) Procede de preparation de 3-iodorifamycine s et de 3-bromorifamycine s
FR2396584B1 (fr) Procede d'homogeneisation
BE867135A (fr) Procede et machine d'enduction
GB2036728B (en) Dimetylbenzylacetamide derivatives and their production and use
JPS54163893A (en) Biological substance and production
IT7924739A0 (it) Apparato regolatore della sensibilita'.

Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: GENENTECH INC.

Effective date: 19981106