JPH053851B2 - - Google Patents
Info
- Publication number
- JPH053851B2 JPH053851B2 JP60068512A JP6851285A JPH053851B2 JP H053851 B2 JPH053851 B2 JP H053851B2 JP 60068512 A JP60068512 A JP 60068512A JP 6851285 A JP6851285 A JP 6851285A JP H053851 B2 JPH053851 B2 JP H053851B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- isoquinolinesulfonyl
- acid
- homopiperazine
- methylhomopiperazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6851285A JPS61227581A (ja) | 1985-04-02 | 1985-04-02 | 血管拡張剤 |
AT85116520T ATE64598T1 (de) | 1984-12-27 | 1985-12-23 | Substituierte isochinolinsulfonyl-verbindungen. |
EP19850116520 EP0187371B1 (en) | 1984-12-27 | 1985-12-23 | Substituted isoquinolinesulfonyl compounds |
DE8585116520T DE3583287D1 (de) | 1984-12-27 | 1985-12-23 | Substituierte isochinolinsulfonyl-verbindungen. |
US06813973 US4678783B1 (en) | 1983-11-04 | 1985-12-27 | Substituted isoquinolinesulfonyl compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6851285A JPS61227581A (ja) | 1985-04-02 | 1985-04-02 | 血管拡張剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61227581A JPS61227581A (ja) | 1986-10-09 |
JPH053851B2 true JPH053851B2 (enrdf_load_html_response) | 1993-01-18 |
Family
ID=13375841
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6851285A Granted JPS61227581A (ja) | 1983-11-04 | 1985-04-02 | 血管拡張剤 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS61227581A (enrdf_load_html_response) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0667926B2 (ja) * | 1985-11-12 | 1994-08-31 | 旭化成工業株式会社 | 環状のイソキノリンスルホンアミド誘導体 |
JP2720348B2 (ja) * | 1989-03-30 | 1998-03-04 | 旭化成工業株式会社 | 脳細胞機能障害改善剤 |
JP2893029B2 (ja) * | 1992-08-10 | 1999-05-17 | 旭化成工業株式会社 | 心臓保護剤 |
JPH0680569A (ja) * | 1992-09-03 | 1994-03-22 | Asahi Chem Ind Co Ltd | 血小板凝集阻害剤 |
CN1210521A (zh) * | 1996-02-02 | 1999-03-10 | 日本新药株式会社 | 异喹啉衍生物及医药 |
US6218410B1 (en) * | 1996-08-12 | 2001-04-17 | Yoshitomi Pharmaceutical Industries, Ltd. | Medicines comprising Rho kinase inhibitor |
WO1999054306A1 (fr) * | 1997-03-10 | 1999-10-28 | Hiroyoshi Hidaka | Derives isoquinolinesulfonamide et medicaments integrant ces derives comme principe actif |
WO2000009133A1 (en) * | 1998-08-10 | 2000-02-24 | Asahi Kasei Kogyo Kabushiki Kaisha | Sustained release oral preparations of fasudil hydrochloride |
DE60045890D1 (de) | 1999-04-27 | 2011-06-09 | Mitsubishi Tanabe Pharma Corp | Arzneimittel zur präventiven oder therapeutische Behandlung von Lebererkrankungen |
JP4582561B2 (ja) * | 2000-10-23 | 2010-11-17 | 旭化成ファーマ株式会社 | 移植による血管病変の発生抑制剤 |
CN1914194B (zh) * | 2004-01-29 | 2011-08-31 | 旭化成制药株式会社 | 用于伴随旁路术的血管痉挛的治疗剂 |
JP4789264B2 (ja) * | 2004-03-16 | 2011-10-12 | 旭化成ファーマ株式会社 | ファスジル含有製剤及びその安定性を改善する方法 |
ATE423779T1 (de) | 2005-04-25 | 2009-03-15 | Western Therapeutics Inst Inc | Hochselektiver rho-kinase-inhibitor |
US8193193B2 (en) | 2005-07-12 | 2012-06-05 | Kowa Co., Ltd. | Agent for prevention or treatment of glaucoma |
US8283337B2 (en) | 2007-02-23 | 2012-10-09 | Next21 K.K. | Therapeutic or prophylactic agent for vasoconstriction |
CN103951624B (zh) * | 2010-08-26 | 2019-04-16 | 兴和株式会社 | 1,4-二氮杂环庚烷衍生物或其盐的制造方法 |
WO2019057121A1 (zh) * | 2017-09-25 | 2019-03-28 | 南京明德新药研发股份有限公司 | 一种异喹啉磺酰衍生物的晶型及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0227992B2 (ja) * | 1982-01-14 | 1990-06-20 | Asahi Kasei Kogyo Kk | Isokinorinsuruhonirukagobutsu |
JPS57200366A (en) * | 1981-06-01 | 1982-12-08 | Asahi Chem Ind Co Ltd | Isoquinoline compound |
JPS5993054A (ja) * | 1982-11-18 | 1984-05-29 | Asahi Chem Ind Co Ltd | イソキノリンスルホン酸アミド誘導体 |
-
1985
- 1985-04-02 JP JP6851285A patent/JPS61227581A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS61227581A (ja) | 1986-10-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXPY | Cancellation because of completion of term |