JPH0536411B2 - - Google Patents

Info

Publication number
JPH0536411B2
JPH0536411B2 JP62075470A JP7547087A JPH0536411B2 JP H0536411 B2 JPH0536411 B2 JP H0536411B2 JP 62075470 A JP62075470 A JP 62075470A JP 7547087 A JP7547087 A JP 7547087A JP H0536411 B2 JPH0536411 B2 JP H0536411B2
Authority
JP
Japan
Prior art keywords
substance
solid solution
solution composition
liters
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62075470A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62277321A (ja
Inventor
Yoshio Ueda
Fumio Shimojo
Yasuo Shimazaki
Kazutake Sumi
Toshasu Pponbo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS62277321A publication Critical patent/JPS62277321A/ja
Publication of JPH0536411B2 publication Critical patent/JPH0536411B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Reinforced Plastic Materials (AREA)
  • Cosmetics (AREA)
  • Colloid Chemistry (AREA)
JP62075470A 1986-04-02 1987-03-27 Ｆｒ―９００５０６物質の固形医薬製剤用固溶体組成物 Granted JPS62277321A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868608080A GB8608080D0 (en) 1986-04-02 1986-04-02 Solid dispersion composition
GB8608080 1986-04-02

Publications (2)

Publication Number Publication Date
JPS62277321A JPS62277321A (ja) 1987-12-02
JPH0536411B2 true JPH0536411B2 (enExample) 1993-05-31

Family

ID=10595572

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62075470A Granted JPS62277321A (ja) 1986-04-02 1987-03-27 Ｆｒ―９００５０６物質の固形医薬製剤用固溶体組成物

Country Status (16)

Country Link
US (1) US4916138A (enExample)
EP (1) EP0240773B1 (enExample)
JP (1) JPS62277321A (enExample)
KR (2) KR950007209B1 (enExample)
AT (1) ATE73327T1 (enExample)
CA (1) CA1302279C (enExample)
DE (1) DE3777223D1 (enExample)
DK (1) DK174979B1 (enExample)
ES (1) ES2032397T3 (enExample)
GB (1) GB8608080D0 (enExample)
GR (1) GR3004124T3 (enExample)
HK (1) HK6397A (enExample)
IE (1) IE59712B1 (enExample)
MX (1) MX9202945A (enExample)
RU (1) RU1826977C (enExample)
UA (1) UA13209A (enExample)

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US5143918A (en) * 1990-10-11 1992-09-01 Merck & Co., Inc. Halomacrolides and derivatives having immunosuppressive activity
US5147877A (en) * 1991-04-18 1992-09-15 Merck & Co. Inc. Semi-synthetic immunosuppressive macrolides
US5250678A (en) 1991-05-13 1993-10-05 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity
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US20040176358A1 (en) * 1999-04-30 2004-09-09 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
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Also Published As

Publication number Publication date
ES2032397T3 (es) 1993-02-16
KR950007210B1 (ko) 1995-07-04
KR890001626A (ko) 1989-03-28
GR3004124T3 (enExample) 1993-03-31
DK140487D0 (da) 1987-03-18
ATE73327T1 (de) 1992-03-15
KR950007209B1 (ko) 1995-07-04
DK174979B1 (da) 2004-04-05
UA13209A (uk) 1997-02-28
IE870843L (en) 1987-10-02
US4916138A (en) 1990-04-10
EP0240773B1 (en) 1992-03-11
IE59712B1 (en) 1994-03-23
KR870010073A (ko) 1987-11-30
JPS62277321A (ja) 1987-12-02
MX9202945A (es) 1992-07-01
HK6397A (en) 1997-01-24
DE3777223D1 (de) 1992-04-16
RU1826977C (ru) 1993-07-07
EP0240773A1 (en) 1987-10-14
GB8608080D0 (en) 1986-05-08
DK140487A (da) 1987-10-03
CA1302279C (en) 1992-06-02

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