ES2032397T3 - Procedimiento para preparar una composicion en dispersion solida de la sustancia fr-900506 - Google Patents
Procedimiento para preparar una composicion en dispersion solida de la sustancia fr-900506Info
- Publication number
- ES2032397T3 ES2032397T3 ES198787103716T ES87103716T ES2032397T3 ES 2032397 T3 ES2032397 T3 ES 2032397T3 ES 198787103716 T ES198787103716 T ES 198787103716T ES 87103716 T ES87103716 T ES 87103716T ES 2032397 T3 ES2032397 T3 ES 2032397T3
- Authority
- ES
- Spain
- Prior art keywords
- solid dispersion
- preparing
- substance
- procedure
- dispersion composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Reinforced Plastic Materials (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868608080A GB8608080D0 (en) | 1986-04-02 | 1986-04-02 | Solid dispersion composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2032397T3 true ES2032397T3 (es) | 1993-02-16 |
Family
ID=10595572
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787103716T Expired - Lifetime ES2032397T3 (es) | 1986-04-02 | 1987-03-14 | Procedimiento para preparar una composicion en dispersion solida de la sustancia fr-900506 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4916138A (enExample) |
| EP (1) | EP0240773B1 (enExample) |
| JP (1) | JPS62277321A (enExample) |
| KR (2) | KR950007209B1 (enExample) |
| AT (1) | ATE73327T1 (enExample) |
| CA (1) | CA1302279C (enExample) |
| DE (1) | DE3777223D1 (enExample) |
| DK (1) | DK174979B1 (enExample) |
| ES (1) | ES2032397T3 (enExample) |
| GB (1) | GB8608080D0 (enExample) |
| GR (1) | GR3004124T3 (enExample) |
| HK (1) | HK6397A (enExample) |
| IE (1) | IE59712B1 (enExample) |
| MX (1) | MX9202945A (enExample) |
| RU (1) | RU1826977C (enExample) |
| UA (1) | UA13209A (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5366971A (en) * | 1987-11-09 | 1994-11-22 | Sandoz Ltd. | Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them |
| JPH02206A (ja) * | 1987-11-11 | 1990-01-05 | Fujisawa Pharmaceut Co Ltd | エキシホンと水溶性高分子化合物とを含有することを特徴とする新規製剤 |
| PH26518A (en) * | 1987-11-11 | 1992-08-07 | Fujisawa Pharmaceutical Co | A novel pharmaceutical composition comprising exifone and water-soluble polymer |
| FR2640137A1 (fr) * | 1988-12-08 | 1990-06-15 | Texinfine Sa | Systemes transporteurs de principes actifs lipophiles et leur procede d'obtention |
| ZA905202B (en) * | 1989-07-05 | 1991-04-24 | Fujisawa Pharmaceutical Co | Aqueous liquid composition for external use |
| US5208228A (en) * | 1989-11-13 | 1993-05-04 | Merck & Co., Inc. | Aminomacrolides and derivatives having immunosuppressive activity |
| KR0177158B1 (ko) * | 1990-03-01 | 1999-03-20 | 후지사와 도모기찌로 | 면역억제 활성을 갖는 트리사이클릭 화합물 함유 용액 제제 |
| DK0489181T3 (da) * | 1990-07-19 | 1996-11-18 | Otsuka Pharma Co Ltd | Fast præparat |
| US5143918A (en) * | 1990-10-11 | 1992-09-01 | Merck & Co., Inc. | Halomacrolides and derivatives having immunosuppressive activity |
| US5147877A (en) * | 1991-04-18 | 1992-09-15 | Merck & Co. Inc. | Semi-synthetic immunosuppressive macrolides |
| US5250678A (en) | 1991-05-13 | 1993-10-05 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
| US5162334A (en) * | 1991-05-13 | 1992-11-10 | Merck & Co., Inc. | Amino O-alkyl, O-alkenyl and O-alkynlmacrolides having immunosuppressive activity |
| US5565560A (en) * | 1991-05-13 | 1996-10-15 | Merck & Co., Inc. | O-Aryl,O-alkyl,O-alkenyl and O-alkynylmacrolides having immunosuppressive activity |
| US5189042A (en) * | 1991-08-22 | 1993-02-23 | Merck & Co. Inc. | Fluoromacrolides having immunosuppressive activity |
| US5208241A (en) * | 1991-09-09 | 1993-05-04 | Merck & Co., Inc. | N-heteroaryl, n-alkylheteroaryl, n-alkenylheteroaryl and n-alkynylheteroarylmacrolides having immunosuppressive activity |
| ATE183083T1 (de) * | 1992-11-18 | 1999-08-15 | Fujisawa Pharmaceutical Co | Pharmazeutische zubereitung mit verlängerter wirkung |
| DE4316537A1 (de) * | 1993-05-18 | 1994-11-24 | Basf Ag | Zubereitungen in Form fester Lösungen |
| US5693648A (en) * | 1994-09-30 | 1997-12-02 | Merck & Co., Inc. | O-aryl, O-alkyl, O-alkenyl and O-alkynyl-macrolides having immunosuppressive activity |
| BE1009856A5 (fr) * | 1995-07-14 | 1997-10-07 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule. |
| JP3266005B2 (ja) | 1995-09-19 | 2002-03-18 | 藤沢薬品工業株式会社 | エアゾール製剤およびその製造方法 |
| ZA9710927B (en) * | 1996-12-06 | 1998-06-15 | Fujisawa Pharmaceutical Co | Pharmaceutical composition. |
| KR20010006070A (ko) | 1997-04-11 | 2001-01-15 | 후지야마 아키라 | 의약조성물 |
| NZ507211A (en) | 1998-03-26 | 2003-07-25 | Fujisawa Pharmaceutical Co | Sustained release preparations |
| US6350786B1 (en) * | 1998-09-22 | 2002-02-26 | Hoffmann-La Roche Inc. | Stable complexes of poorly soluble compounds in ionic polymers |
| CN100381566C (zh) | 1998-11-20 | 2008-04-16 | 科森生物科学公司 | 产生环氧噻酮及其衍生物的重组方法和材料 |
| US6410301B1 (en) | 1998-11-20 | 2002-06-25 | Kosan Biosciences, Inc. | Myxococcus host cells for the production of epothilones |
| CA2372150C (en) * | 1999-04-30 | 2011-08-30 | The Regents Of The University Of Michigan | Therapeutic applications of pro-apoptotic benzodiazepines |
| US7572788B2 (en) | 1999-04-30 | 2009-08-11 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US7063857B1 (en) | 1999-04-30 | 2006-06-20 | Sucampo Ag | Use of macrolide compounds for the treatment of dry eye |
| US20050113460A1 (en) * | 1999-04-30 | 2005-05-26 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US20030119029A1 (en) * | 1999-04-30 | 2003-06-26 | Regents Of The University Of Michigan | Compositions and methods relating to novel benzodiazepine compounds and targets thereof |
| US20040176358A1 (en) * | 1999-04-30 | 2004-09-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| US20060025388A1 (en) * | 1999-04-30 | 2006-02-02 | Glick Gary D | Compositions and methods relating to novel compounds and targets thereof |
| WO2001060833A2 (en) | 2000-02-18 | 2001-08-23 | Kosan Biosciences, Inc. | Motilide compounds |
| US6750047B2 (en) * | 2000-08-21 | 2004-06-15 | Kosan Biosciences, Inc. | Fermentation and purification of migrastatin and analog |
| GB0108498D0 (en) * | 2001-04-04 | 2001-05-23 | Novartis Ag | Organic Compounds |
| WO2003000235A1 (en) * | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions of dispersions of drugs and neutral polymers |
| GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
| US6989131B2 (en) * | 2002-03-12 | 2006-01-24 | Uop Llc | Catalytic reactor with integral evaporator |
| DK1532131T3 (da) * | 2002-08-29 | 2009-02-09 | Pfizer | Motilid-forbindelser |
| BRPI0412329A (pt) * | 2003-07-09 | 2006-09-05 | Chong Kun Dang Pharm Corp | dispersão sólida de tacrolimus e método de processar a mesma |
| JP4903568B2 (ja) * | 2003-08-29 | 2012-03-28 | ベロクシス ファーマシューティカルズ エー/エス | タクロリムスを含む固体分散体 |
| EP1663217B1 (en) | 2003-08-29 | 2010-07-07 | LifeCycle Pharma A/S | Solid dispersions comprising tacrolimus |
| US20090275099A1 (en) * | 2004-04-27 | 2009-11-05 | Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| US20050272723A1 (en) * | 2004-04-27 | 2005-12-08 | The Regents Of The University Of Michigan | Methods and compositions for treating diseases and conditions associated with mitochondrial function |
| EP1768662A2 (en) | 2004-06-24 | 2007-04-04 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
| US20060014677A1 (en) * | 2004-07-19 | 2006-01-19 | Isotechnika International Inc. | Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds |
| US20060052369A1 (en) * | 2004-09-07 | 2006-03-09 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| AU2006203946B2 (en) * | 2005-01-03 | 2009-07-23 | The Regents Of The University Of Michigan | Compositions and methods relating to novel compounds and targets thereof |
| KR100678824B1 (ko) * | 2005-02-04 | 2007-02-05 | 한미약품 주식회사 | 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물 |
| EP1893218A4 (en) | 2005-06-01 | 2011-01-12 | Univ Michigan | UNLOCKED BENZODIAZEPINE COMPOSITIONS AND METHOD |
| US20070105844A1 (en) * | 2005-10-26 | 2007-05-10 | Regents Of The University Of Michigan | Therapeutic compositions and methods |
| CA2628193C (en) | 2005-11-01 | 2012-08-14 | The Regents Of The University Of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
| GB0602632D0 (en) * | 2006-02-08 | 2006-03-22 | Pliva Istrazivacki Inst D O O | Preparation Of A Solid Dosage From Comprising Tacrolimus And/Or Sirolimus |
| US7759338B2 (en) * | 2006-04-27 | 2010-07-20 | The Regents Of The University Of Michigan | Soluble 1,4 benzodiazepine compounds and stable salts thereof |
| MX2008015488A (es) | 2006-06-09 | 2009-02-12 | Univ Michigan | Composiciones y metodos relacionados con compuestos novedosos y objetivos de los mismos. |
| EP2067475A4 (en) * | 2006-09-26 | 2010-12-15 | Astellas Pharma Inc | PREPARATION FOR TACROLIMUS MAINTAINED RELEASE |
| JPWO2008084698A1 (ja) | 2006-12-28 | 2010-04-30 | アステラス製薬株式会社 | タクロリムス徐放性医薬組成物 |
| BRPI0808653A2 (pt) * | 2007-03-09 | 2014-08-19 | Univ Michigan | Composições e métodos referindo-se a novos compostos e alvos dos mesmos. |
| US12083103B2 (en) | 2007-05-30 | 2024-09-10 | Veloxis Pharmaceuticals, Inc. | Tacrolimus for improved treatment of transplant patients |
| ES2634153T3 (es) | 2007-05-30 | 2017-09-26 | Veloxis Pharmaceuticals A/S | Forma de dosificación oral de una vez al día que comprende tacrolimus |
| ES2614498T3 (es) | 2007-09-14 | 2017-05-31 | The Regents Of The University Of Michigan | Inhibidores de ATPasa F1F0 y métodos relacionados |
| TW200932240A (en) | 2007-10-25 | 2009-08-01 | Astellas Pharma Inc | Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production |
| AU2008323945B2 (en) | 2007-11-06 | 2013-11-28 | The Regents Of The University Of Michigan | Benzodiazepinone compounds useful in the treatment of skin conditions |
| CL2008000374A1 (es) * | 2008-02-05 | 2008-04-04 | Igloo Zone Chile S A | Composicion farmaceutica que comprende un polvo para suspension oral de tacrolimus o una de sus sales, hidratos o solvatos y excipientes farmaceuticamente aceptables; procedimiento de preparacion de dicha composicion farmaceutica; y uso para la preve |
| KR101003042B1 (ko) | 2008-03-17 | 2010-12-21 | 종근당바이오 주식회사 | 고순도 타크로리무스의 정제 방법 |
| US8222272B2 (en) * | 2008-04-11 | 2012-07-17 | Roxane Laboratories, Inc. | Pharmaceutical formulation and process comprising a solid dispersion of macrolide (tacrolimus) |
| US12403095B2 (en) | 2008-05-30 | 2025-09-02 | Veloxis Pharmaceuticals, Inc. | Stabilized tacrolimus composition |
| EP2352724B1 (en) | 2008-09-11 | 2015-04-22 | The Regents of the University of Michigan | Aryl guanidine f1f0-atpase inhibitors and their medical use |
| WO2010121164A2 (en) | 2009-04-17 | 2010-10-21 | The Regents Of The University Of Michigan | 1,4-benzodiazepinone compounds and their use in treating cancer |
| US8673897B2 (en) | 2009-09-18 | 2014-03-18 | The Regents Of The University Of Michigan | Benzodiazepinone compounds and methods of treatment using same |
| CA2780333C (en) | 2009-11-17 | 2016-05-24 | The Regents Of The University Of Michigan | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties |
| JP5856064B2 (ja) | 2009-11-17 | 2016-02-09 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 治療特性を有する1,4−ベンゾジアゼピン−2,5−ジオンおよび関連化合物 |
| TWI510238B (zh) | 2010-02-17 | 2015-12-01 | Lifecycle Pharma As | 穩定化他克莫司(tacrolimus)組合物 |
| WO2011157721A2 (en) | 2010-06-14 | 2011-12-22 | Ratiopharm Gmbh | Ivabradine-containing pharmaceutical composition |
| MA34586B1 (fr) | 2010-08-25 | 2013-10-02 | Medis Lab | Particules cristallines de tacrolimus micronise a surface modifiee et compositions pharmaceutiques associees |
| KR101243938B1 (ko) * | 2010-10-19 | 2013-03-19 | 이희엽 | 타크롤리무스를 유효성분으로 함유하는 서방형 펠렛 |
| PT2836559T (pt) * | 2012-04-11 | 2016-08-31 | Dow Global Technologies Llc | Composição que compreende um diluente orgânico e um éter de celulose. |
| CN105530918A (zh) * | 2013-09-25 | 2016-04-27 | 陶氏环球技术有限责任公司 | 包含有机液体稀释剂和特定羟烷基甲基纤维素的组合物 |
| CN105828827A (zh) | 2014-11-21 | 2016-08-03 | 杭州领业医药科技有限公司 | 一种含他克莫司的药物组合物及其制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL130099C (enExample) * | 1963-10-11 | |||
| DE1492034A1 (de) * | 1965-05-18 | 1969-02-20 | Merck Ag E | Verfahren zur Herstellung fester haltbarer Zubereitungen von empfindlichen,in Wasser schwer loeslichen Wirkstoffen,vorzugsweise Arzneimitteln |
| US3852421A (en) * | 1970-03-23 | 1974-12-03 | Shinetsu Chemical Co | Excipient and shaped medicaments prepared therewith |
| GB1322306A (en) * | 1971-04-15 | 1973-07-04 | Meiji Seika Co | Stabilized antibiotic preparation and manufacturing process therefor |
| US4127647A (en) * | 1975-04-08 | 1978-11-28 | Meiji Seika Kaisha, Ltd. | Process for preparation of stable amorphous macrolide antibiotic solids |
| GB1593261A (en) * | 1976-07-23 | 1981-07-15 | Inveresk Res Int | Controlled release suppository |
| GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
| DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
| CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
| US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
| US4369172A (en) * | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| JPS6038322A (ja) * | 1983-08-11 | 1985-02-27 | Fujisawa Pharmaceut Co Ltd | ジヒドロピリジンa物質含有易溶性固形製剤 |
| US4894366A (en) * | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
-
1986
- 1986-04-02 GB GB868608080A patent/GB8608080D0/en active Pending
-
1987
- 1987-03-14 EP EP87103716A patent/EP0240773B1/en not_active Expired - Lifetime
- 1987-03-14 AT AT87103716T patent/ATE73327T1/de not_active IP Right Cessation
- 1987-03-14 DE DE8787103716T patent/DE3777223D1/de not_active Expired - Lifetime
- 1987-03-14 ES ES198787103716T patent/ES2032397T3/es not_active Expired - Lifetime
- 1987-03-18 DK DK198701404A patent/DK174979B1/da not_active IP Right Cessation
- 1987-03-27 JP JP62075470A patent/JPS62277321A/ja active Granted
- 1987-04-01 CA CA000533582A patent/CA1302279C/en not_active Expired - Lifetime
- 1987-04-01 KR KR1019870003087A patent/KR950007209B1/ko not_active Expired - Lifetime
- 1987-04-01 RU SU4202275A patent/RU1826977C/ru active
- 1987-04-01 IE IE84387A patent/IE59712B1/en not_active IP Right Cessation
- 1987-04-01 UA UA4202275A patent/UA13209A/uk unknown
- 1987-07-01 KR KR1019870007053A patent/KR950007210B1/ko not_active Expired - Lifetime
-
1988
- 1988-07-25 US US07/224,235 patent/US4916138A/en not_active Expired - Lifetime
-
1992
- 1992-03-24 GR GR910402151T patent/GR3004124T3/el unknown
- 1992-06-17 MX MX9202945A patent/MX9202945A/es unknown
-
1997
- 1997-01-16 HK HK6397A patent/HK6397A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR950007209B1 (ko) | 1995-07-04 |
| DK174979B1 (da) | 2004-04-05 |
| RU1826977C (ru) | 1993-07-07 |
| GB8608080D0 (en) | 1986-05-08 |
| GR3004124T3 (enExample) | 1993-03-31 |
| CA1302279C (en) | 1992-06-02 |
| KR950007210B1 (ko) | 1995-07-04 |
| KR870010073A (ko) | 1987-11-30 |
| DK140487A (da) | 1987-10-03 |
| JPH0536411B2 (enExample) | 1993-05-31 |
| IE870843L (en) | 1987-10-02 |
| KR890001626A (ko) | 1989-03-28 |
| US4916138A (en) | 1990-04-10 |
| HK6397A (en) | 1997-01-24 |
| EP0240773A1 (en) | 1987-10-14 |
| JPS62277321A (ja) | 1987-12-02 |
| DE3777223D1 (de) | 1992-04-16 |
| IE59712B1 (en) | 1994-03-23 |
| EP0240773B1 (en) | 1992-03-11 |
| MX9202945A (es) | 1992-07-01 |
| DK140487D0 (da) | 1987-03-18 |
| UA13209A (uk) | 1997-02-28 |
| ATE73327T1 (de) | 1992-03-15 |
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