JPH0529216B2 - - Google Patents

Info

Publication number
JPH0529216B2
JPH0529216B2 JP60504073A JP50407385A JPH0529216B2 JP H0529216 B2 JPH0529216 B2 JP H0529216B2 JP 60504073 A JP60504073 A JP 60504073A JP 50407385 A JP50407385 A JP 50407385A JP H0529216 B2 JPH0529216 B2 JP H0529216B2
Authority
JP
Japan
Prior art keywords
acid
aryl
fluoro
threo
propanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60504073A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62500519A (ja
Inventor
Tatsutanahari Rakushuminarayan Nagabushan
Suchuaato Uorutaa Matsukukomubii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schering Plough Corp
Original Assignee
Schering Plough Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Plough Corp filed Critical Schering Plough Corp
Publication of JPS62500519A publication Critical patent/JPS62500519A/ja
Publication of JPH0529216B2 publication Critical patent/JPH0529216B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
    • C07D301/14—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP60504073A 1984-09-19 1985-09-17 （スレオ）−１−アリ−ル−２−アシルアミド−３−フルオル−１−プロパノ−ル類の製造 Granted JPS62500519A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US651980 1984-09-19
US06/651,980 US4582918A (en) 1984-09-19 1984-09-19 Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols

Publications (2)

Publication Number Publication Date
JPS62500519A JPS62500519A (ja) 1987-03-05
JPH0529216B2 true JPH0529216B2 (enExample) 1993-04-28

Family

ID=24615030

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60504073A Granted JPS62500519A (ja) 1984-09-19 1985-09-17 （スレオ）−１−アリ−ル−２−アシルアミド−３−フルオル−１−プロパノ−ル類の製造

Country Status (18)

Country Link
US (1) US4582918A (enExample)
EP (1) EP0200739B1 (enExample)
JP (1) JPS62500519A (enExample)
KR (1) KR900001509B1 (enExample)
AR (1) AR245445A1 (enExample)
AT (1) ATE44735T1 (enExample)
AU (1) AU577622B2 (enExample)
CA (1) CA1262553A (enExample)
DE (1) DE3571613D1 (enExample)
DK (1) DK173703B1 (enExample)
ES (1) ES8702339A1 (enExample)
HU (1) HU196198B (enExample)
IE (1) IE58491B1 (enExample)
IL (1) IL76432A (enExample)
NZ (1) NZ213508A (enExample)
SG (1) SG39092G (enExample)
WO (1) WO1986001799A1 (enExample)
ZA (1) ZA857132B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973750A (en) * 1984-09-19 1990-11-27 Schering Corporation Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
DE3543021A1 (de) * 1985-12-05 1987-06-11 Boehringer Mannheim Gmbh Verbesserte verfahren zur herstellung von d-threo-1-(p-methylsulfonylphenyl) -2-dichloracetamido-propandiol-1,3-(thiamphenicol) sowie verwendung geeigneter zwischenprodukte
US5084583A (en) * 1989-10-12 1992-01-28 E. I. Du Pont De Nemours And Company Epoxidation of fluorine containing olefins
IT1249048B (it) 1991-02-21 1995-02-11 Zambon Spa Processo per la preparazione di trans-(5r)-2-ossazoline -2,4,5, trisostituite
US5346828A (en) * 1991-03-27 1994-09-13 Celgene Corporation Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase
IL134144A (en) * 1999-02-19 2004-02-08 Akzo Nobel Nv Process for the preparation of a-droxy organic acids
JP2005538937A (ja) * 2002-03-08 2005-12-22 シェーリング−プラウ， リミテッド 新規なフロルフェニコール型抗生物質
US20040202762A1 (en) * 2003-04-08 2004-10-14 Ducharme Paul E Smoked nonfibrous casing
US7126005B2 (en) 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol
JP4792032B2 (ja) * 2004-08-13 2011-10-12 シェーリング−プラウ・リミテッド 抗生物質、トリアゾールおよびコルチコステロイドを含む薬学的処方物
NZ553777A (en) 2004-09-23 2010-11-26 Schering Plough Ltd Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
MX2007006072A (es) * 2004-11-19 2007-07-11 Schering Plough Ltd Control de parasitos en animales mediante el uso de derivados del parasiticida 2-fenil-3-(1h-pirrol-2-il)acrilonitrilo.
DE602005010479D1 (de) * 2004-12-21 2008-11-27 Intervet Int Bv Injizierbare veterinärmedizinische zusammensetzung enthaltend florfenicol
EP1890547A2 (en) * 2005-06-09 2008-02-27 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
EP2091909A1 (en) * 2006-12-13 2009-08-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
MX2009006467A (es) * 2006-12-13 2009-08-21 Schering Plough Ltd Profarmacos solubles en agua de cloranfenicol, tiamfenicol y analogos de los mismos.
CN101686956A (zh) * 2007-04-27 2010-03-31 谢尔英·普劳有限公司 用环糊精增加氟苯尼考及结构相关的抗生素的溶解度的化合物和方法
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
MX368680B (es) 2007-06-27 2019-10-11 Du Pont Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga.
ES2715049T3 (es) * 2007-11-09 2019-05-31 Intervet Int Bv Formulación sólida de liberación rápida, preparación y uso de la misma
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
CA2732017A1 (en) * 2008-07-30 2010-02-04 Intervet International B.V. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
BR112012002524A2 (pt) 2009-08-05 2019-09-24 Du Pont "composto de fórmula, composição, composição para proteger um animal de uma praga parasítica de invertebrados, métodos para controlar uma praga invertebrada e semente tratada"
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
EP2461684A2 (en) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Mesoionic pesticides
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
MA34247B1 (fr) 2010-05-27 2013-05-02 Du Pont Forme cristalline du 4-[5-[3-chloro-5-(trifluorométhyl) phényl] -4,5-dihydro-5-(trifluorométhyl)-3-isoxazolyl]-n-[2-oxo-2-[(2, 2,2-trifluoroéthyl) amino] éthyl]-1-naphtalènecarboxamide
JP5716349B2 (ja) * 2010-10-22 2015-05-13 住友化学株式会社 エポキシアルコール化合物の取得方法、並びにエポキシアルコール化合物及びトリアゾール化合物の製造方法
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD83161A (enExample) *
US3849482A (en) * 1967-10-30 1974-11-19 Merck & Co Inc Amine salts of cis-propenylphosphonic acid
LU79970A1 (fr) * 1978-07-13 1980-02-14 Continental Pharma Procede de preparation de derives de 1-phenyl-1-propanol
ES488154A0 (es) * 1979-02-05 1981-04-16 Schering Corp Un procedimiento para la preparacion de un compuesto d-(treo-1-aril-2-acilamido-3-fluor-1-propanol
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor

Also Published As

Publication number Publication date
IE58491B1 (en) 1993-09-22
ZA857132B (en) 1986-05-28
SG39092G (en) 1992-05-22
IL76432A (en) 1989-02-28
ATE44735T1 (de) 1989-08-15
ES8702339A1 (es) 1986-12-16
IE852296L (en) 1986-03-19
NZ213508A (en) 1989-05-29
DK224086D0 (da) 1986-05-14
DE3571613D1 (en) 1989-08-24
KR900001509B1 (ko) 1990-03-12
AR245445A1 (es) 1994-01-31
ES547083A0 (es) 1986-12-16
US4582918A (en) 1986-04-15
CA1262553A (en) 1989-10-31
DK173703B1 (da) 2001-07-09
AU577622B2 (en) 1988-09-29
EP0200739A1 (en) 1986-11-12
KR870700614A (ko) 1987-12-30
HUT45243A (en) 1988-06-28
HU196198B (en) 1988-10-28
JPS62500519A (ja) 1987-03-05
AU4809785A (en) 1986-04-08
IL76432A0 (en) 1986-01-31
WO1986001799A1 (en) 1986-03-27
EP0200739B1 (en) 1989-07-19
DK224086A (da) 1986-05-14

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