AR245445A1 - Procedimiento para la preparacion de cis-1-aril-2-(fluormetil)oxiranos,compuestos asi obtenidos y preparacion de (treo)-1-aril-2-acilamido-3-fluor-1-propanoles utilizando dichos compuestos. - Google Patents

Procedimiento para la preparacion de cis-1-aril-2-(fluormetil)oxiranos,compuestos asi obtenidos y preparacion de (treo)-1-aril-2-acilamido-3-fluor-1-propanoles utilizando dichos compuestos.

Info

Publication number
AR245445A1
AR245445A1 AR85301633A AR30163385A AR245445A1 AR 245445 A1 AR245445 A1 AR 245445A1 AR 85301633 A AR85301633 A AR 85301633A AR 30163385 A AR30163385 A AR 30163385A AR 245445 A1 AR245445 A1 AR 245445A1
Authority
AR
Argentina
Prior art keywords
aryl
preparation
propanols
acylamido
threo
Prior art date
Application number
AR85301633A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of AR245445A1 publication Critical patent/AR245445A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
    • C07D301/14—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE CIS-1-ARIL-2-(FLUORMETIL)OXIRANOS LAS FORMULA IVA Y IVB, DONDE ARILO ES (I) Y DONDE R1 ES ALQUILO, OBTENIDO POR PONER EN CONTACTO UN CIS-1-ARIL-3-FLUOR-1-PROPANO CON UN PEROXIACIDO ALIFATICO O AROMATICO PARA FORMAR LOS COMPUESTOS REPRESENTADOS POR LAS FORMULAS IVA Y IVB.
AR85301633A 1984-09-19 1985-09-17 Procedimiento para la preparacion de cis-1-aril-2-(fluormetil)oxiranos,compuestos asi obtenidos y preparacion de (treo)-1-aril-2-acilamido-3-fluor-1-propanoles utilizando dichos compuestos. AR245445A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/651,980 US4582918A (en) 1984-09-19 1984-09-19 Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols

Publications (1)

Publication Number Publication Date
AR245445A1 true AR245445A1 (es) 1994-01-31

Family

ID=24615030

Family Applications (1)

Application Number Title Priority Date Filing Date
AR85301633A AR245445A1 (es) 1984-09-19 1985-09-17 Procedimiento para la preparacion de cis-1-aril-2-(fluormetil)oxiranos,compuestos asi obtenidos y preparacion de (treo)-1-aril-2-acilamido-3-fluor-1-propanoles utilizando dichos compuestos.

Country Status (18)

Country Link
US (1) US4582918A (es)
EP (1) EP0200739B1 (es)
JP (1) JPS62500519A (es)
KR (1) KR900001509B1 (es)
AR (1) AR245445A1 (es)
AT (1) ATE44735T1 (es)
AU (1) AU577622B2 (es)
CA (1) CA1262553A (es)
DE (1) DE3571613D1 (es)
DK (1) DK173703B1 (es)
ES (1) ES8702339A1 (es)
HU (1) HU196198B (es)
IE (1) IE58491B1 (es)
IL (1) IL76432A (es)
NZ (1) NZ213508A (es)
SG (1) SG39092G (es)
WO (1) WO1986001799A1 (es)
ZA (1) ZA857132B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973750A (en) * 1984-09-19 1990-11-27 Schering Corporation Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
DE3543021A1 (de) * 1985-12-05 1987-06-11 Boehringer Mannheim Gmbh Verbesserte verfahren zur herstellung von d-threo-1-(p-methylsulfonylphenyl) -2-dichloracetamido-propandiol-1,3-(thiamphenicol) sowie verwendung geeigneter zwischenprodukte
US5084583A (en) * 1989-10-12 1992-01-28 E. I. Du Pont De Nemours And Company Epoxidation of fluorine containing olefins
IT1249048B (it) 1991-02-21 1995-02-11 Zambon Spa Processo per la preparazione di trans-(5r)-2-ossazoline -2,4,5, trisostituite
US5346828A (en) * 1991-03-27 1994-09-13 Celgene Corporation Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase
IL134144A (en) * 1999-02-19 2004-02-08 Akzo Nobel Nv Process for the preparation of a-droxy organic acids
BR0308289A (pt) * 2002-03-08 2005-01-11 Schering Plough Ltd Antibióticos do tipo florfenicol
US20040202762A1 (en) * 2003-04-08 2004-10-14 Ducharme Paul E Smoked nonfibrous casing
US7126005B2 (en) 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol
AU2005272925B2 (en) * 2004-08-13 2011-02-10 Intervet International B.V. Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid
EP1799636B1 (en) 2004-09-23 2008-08-27 Schering-Plough Ltd. Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
US7705038B2 (en) * 2004-11-19 2010-04-27 Intervet, Inc. Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives
PL1830885T3 (pl) * 2004-12-21 2009-04-30 Intervet Int Bv Iniekcyjna kompozycja weterynaryjna zawierająca florfenikol
CA2609574A1 (en) * 2005-06-09 2006-12-21 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
WO2008076259A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
MX2009006467A (es) * 2006-12-13 2009-08-21 Schering Plough Ltd Profarmacos solubles en agua de cloranfenicol, tiamfenicol y analogos de los mismos.
CA2685264A1 (en) * 2007-04-27 2008-11-06 Schering-Plough Ltd. Compounds and methods for enhancing solubility of florfenicol and structurally-related antibiotics using cyclodextrins
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
MX368680B (es) 2007-06-27 2019-10-11 Du Pont Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga.
BRPI0818906A2 (pt) * 2007-11-09 2015-05-12 Intervet Int Bv Formulação sólida de liberação rápida, preparação e uso da mesma
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
WO2010014566A2 (en) * 2008-07-30 2010-02-04 Intervet International B.V. Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
MX2012001646A (es) 2009-08-05 2012-03-21 Du Pont Pesticidas mesoionicos.
JP2013501059A (ja) 2009-08-05 2013-01-10 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー メソイオン性殺虫剤
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
CA2799963C (en) 2010-05-27 2018-01-23 E. I. Du Pont De Nemours And Company Crystalline form of 4- [5 - [3 -chloro-5 - (trifluoromethyl) phenyl] -4,5 -dihydro-5 - (trifluoromethyl) -3 - isoxazolyl] -n- [2-0x0-2- [(2,2,2-trifluoroethyl)amino]ethyl] -1-naphthalenecarboxamide
JP5716349B2 (ja) * 2010-10-22 2015-05-13 住友化学株式会社 エポキシアルコール化合物の取得方法、並びにエポキシアルコール化合物及びトリアゾール化合物の製造方法
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD83161A (es) *
US3849482A (en) * 1967-10-30 1974-11-19 Merck & Co Inc Amine salts of cis-propenylphosphonic acid
LU79970A1 (fr) * 1978-07-13 1980-02-14 Continental Pharma Procede de preparation de derives de 1-phenyl-1-propanol
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
ES8104203A1 (es) * 1979-02-05 1981-04-16 Schering Corp Un procedimiento para la preparacion de un compuesto d-(treo-1-aril-2-acilamido-3-fluor-1-propanol

Also Published As

Publication number Publication date
CA1262553A (en) 1989-10-31
SG39092G (en) 1992-05-22
US4582918A (en) 1986-04-15
IL76432A (en) 1989-02-28
HU196198B (en) 1988-10-28
JPH0529216B2 (es) 1993-04-28
KR870700614A (ko) 1987-12-30
AU4809785A (en) 1986-04-08
AU577622B2 (en) 1988-09-29
DE3571613D1 (en) 1989-08-24
DK224086D0 (da) 1986-05-14
WO1986001799A1 (en) 1986-03-27
IL76432A0 (en) 1986-01-31
KR900001509B1 (ko) 1990-03-12
DK224086A (da) 1986-05-14
ES8702339A1 (es) 1986-12-16
EP0200739B1 (en) 1989-07-19
JPS62500519A (ja) 1987-03-05
ATE44735T1 (de) 1989-08-15
EP0200739A1 (en) 1986-11-12
DK173703B1 (da) 2001-07-09
NZ213508A (en) 1989-05-29
ES547083A0 (es) 1986-12-16
IE58491B1 (en) 1993-09-22
IE852296L (en) 1986-03-19
ZA857132B (en) 1986-05-28
HUT45243A (en) 1988-06-28

Similar Documents

Publication Publication Date Title
AR245445A1 (es) Procedimiento para la preparacion de cis-1-aril-2-(fluormetil)oxiranos,compuestos asi obtenidos y preparacion de (treo)-1-aril-2-acilamido-3-fluor-1-propanoles utilizando dichos compuestos.
AR246265A1 (es) Acidos imidoperxocarboxilicos, procedimientos para su preparacion y su utilizacion.
FI852974L (fi) Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner.
FR2435469A1 (fr) Derives mercaptoacyles de prolines substituees a action hypotensive
BR8900265A (pt) Processo para preparacao de agentes alvejantes
ES2029885T3 (es) Metodo para preparar acidos ariltioalquilfenil-carboxilicos.
ATE47138T1 (de) Verfahren zur herstellung von 1,2-dithiolan-3pentans|ure (thioctsaeure).
SE8302694D0 (sv) Immunomodulating agent
ES2037668T3 (es) Un procedimiento para la produccion de compuestos benzotiazolilazolidinas.
SE8102337L (sv) Radiomottagare
BR8500851A (pt) Processo para produzir um derivado de benzoilureia e processo para produzir uma composicao inseticida e/ou ovicida
SE8401398L (sv) 7-oxabicykloheptansubstituerade prostaglandinanaloger
FR2376143A1 (fr) Bis (amino-4' phenyl)-2,5 oxadiazoles-1,3,4, procede de preparation et utilisation comme composantes bis-diazoiques
ES553413A0 (es) Un procedimiento para la produccion de derivados de benzoilurea
ES548914A0 (es) Procedimiento para la obtencion de n-6-metoxi-5(perfluoroal-quil)-1-naftoil-n-metilglicinas y sus analogos tionaftoili- cos
ATE2685T1 (de) Herstellung von 2-keto-l-gulonsaeure.
PT87162A (pt) Process for the preparation of a pyridil alcanoic acid compoundcontainig a sulphonamido group and of pharmaceutical compositions therewith
ES524524A0 (es) Procedimiento para la preparacion de un aducto de un diisocianato
IT1228934B (it) Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici
ATE23993T1 (de) Verfahren zur herstellung von o,o'dithiobenzamiden.
ES547691A0 (es) Procedimiento para preparar compuestos intermedios para ob- tener derivados de los acidos 16-fenoxi y 16-fenoxi susti- tuido-prostatrienoicos
ATE60779T1 (de) N-glykolylneuraminsaeurederivat.
ATE63119T1 (de) 5- oder 6-substituierte-beta-carbolin-3carbons|ureester.
ATE97657T1 (de) Verfahren zur herstellung von propionsaeurederivaten.
ATE8883T1 (de) Verfahren zur herstellung von nbenzylsubstituierten imiden.