MX368680B - Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga. - Google Patents
Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga.Info
- Publication number
- MX368680B MX368680B MX2014010553A MX2014010553A MX368680B MX 368680 B MX368680 B MX 368680B MX 2014010553 A MX2014010553 A MX 2014010553A MX 2014010553 A MX2014010553 A MX 2014010553A MX 368680 B MX368680 B MX 368680B
- Authority
- MX
- Mexico
- Prior art keywords
- haloalkyl
- halogen
- alkyl
- haloalkoxy
- control method
- Prior art date
Links
- 241000607479 Yersinia pestis Species 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
- 125000006677 (C1-C3) haloalkoxy group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 235000019256 formaldehyde Nutrition 0.000 abstract 1
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 abstract 1
- 125000005347 halocycloalkyl group Chemical group 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000003071 parasitic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invención describe un método para proteger a un animal de una plaga de parásitos invertebrados que comprender tratar al animal por vía oral o inyectable con una cantidad eficaz como pesticida de un compuesto de la Fórmula (1), (ver Fórmula) en donde R1 es halógeno, haloalquilo de C1-C3 o haloalcoxi de C1-C3; R2 es H, halógeno, alquilo de C1-C3, haloalquilo o ciano de C1-C3; R3 es H, halógeno, haloalquilo de C1-C3 o haloalcoxi de C1-C3; R4 es halógeno, alquilo de C1-C3, haloalquilo de C1-C3 o haloalcoxi de C1-C3; R5 es H, CH3, alquicarbonilo de C2-C4, haloalquilcarbonilo de C2-C4, alcoxicarbonilo de C2-C5 o CH2O(alquilo de C1-C3); R6 es alquilo de C1-C6, haloalquilo de C1-C6, cicloalquilo de C3-C6 o halocicloalquilo de C3-C6, cada grupo sustituido con un R7; o R6 es (CH2)mQ; y Q, R7, R8a y R8b son como se define en la descripción.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93738907P | 2007-06-27 | 2007-06-27 | |
| PCT/US2008/068268 WO2009003075A1 (en) | 2007-06-27 | 2008-06-26 | Animal pest control method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX368680B true MX368680B (es) | 2019-10-11 |
Family
ID=40003056
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014010553A MX368680B (es) | 2007-06-27 | 2008-06-26 | Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga. |
| MX2015011173A MX361762B (es) | 2007-06-27 | 2008-06-26 | Metodo de control de plagas en animales. |
| MX2009013748A MX2009013748A (es) | 2007-06-27 | 2008-06-26 | Metodo de control de plagas en animales. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015011173A MX361762B (es) | 2007-06-27 | 2008-06-26 | Metodo de control de plagas en animales. |
| MX2009013748A MX2009013748A (es) | 2007-06-27 | 2008-06-26 | Metodo de control de plagas en animales. |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US11278533B2 (es) |
| EP (3) | EP3351243A1 (es) |
| JP (6) | JP6006471B2 (es) |
| KR (3) | KR101769728B1 (es) |
| CN (2) | CN101743000A (es) |
| AU (1) | AU2008268321C1 (es) |
| BR (1) | BRPI0810929B8 (es) |
| CA (2) | CA2685072C (es) |
| CY (1) | CY1120038T1 (es) |
| DK (2) | DK2957284T3 (es) |
| ES (2) | ES2549731T3 (es) |
| HK (2) | HK1225622A1 (es) |
| HR (2) | HRP20150978T1 (es) |
| HU (1) | HUE037127T2 (es) |
| LT (1) | LT2957284T (es) |
| MX (3) | MX368680B (es) |
| NO (1) | NO2957284T3 (es) |
| PL (1) | PL2957284T3 (es) |
| PT (2) | PT2182945E (es) |
| RU (1) | RU2508102C2 (es) |
| SI (2) | SI2957284T1 (es) |
| WO (1) | WO2009003075A1 (es) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102558082B (zh) | 2004-03-05 | 2015-09-30 | 日产化学工业株式会社 | 异噁唑啉取代苯甲酰胺化合物的制备中间体 |
| TW200803740A (en) * | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| CN101815706A (zh) * | 2007-06-13 | 2010-08-25 | 杜邦公司 | 异*唑啉杀昆虫剂 |
| TWI430995B (zh) * | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| MX368680B (es) * | 2007-06-27 | 2019-10-11 | Du Pont | Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga. |
| TWI600639B (zh) | 2007-08-17 | 2017-10-01 | 杜邦股份有限公司 | 製備5-鹵烷基-4,5-二氫異唑衍生物之化合物 |
| TWI556741B (zh) * | 2007-08-17 | 2016-11-11 | 英特威特國際股份有限公司 | 異唑啉組成物及其作為抗寄生蟲藥上的應用 |
| MX2010003557A (es) * | 2007-10-03 | 2010-04-12 | Du Pont | Compuestos de isoxazolina de naftaleno para el control de plagas de invertebrados. |
| TWI518076B (zh) | 2008-04-09 | 2016-01-21 | 杜邦股份有限公司 | 製備雜環化合物之方法 |
| BRPI0915665B1 (pt) | 2008-07-09 | 2018-01-02 | Basf Se | Misturas pesticidas, métodos para proteger plantas do ataque ou infestação por insetos, acarídeos ou nematódeos, para controlar insetos, aracnídeos ou nematódeos, uso de uma mistura, e, composição pesticida ou parasiticida |
| BRPI0915818A2 (pt) * | 2008-07-09 | 2015-08-04 | Basf Se | Mistura pesticida, composição pesticida, método para controlar fungos nocivos fitopatogênicos, para proteger plantas de fungos nocivos fitopatogênicos, para controlar insetos, aracnídeos ou nematódeos, para proteger plantas do ataque ou infestação por insetos, acarídeos ou nematódeos, e para a proteção de semente, semente, e, uso de uma mistura. |
| AU2009270255B2 (en) | 2008-07-09 | 2013-12-12 | Nissan Chemical Corporation | Process for production of isoxazoline-substituted benzoic acid amide compound |
| EA201100356A1 (ru) | 2008-08-22 | 2011-10-31 | Зингента Партисипейшнс Аг | Инсектицидные соединения |
| US20110269804A1 (en) | 2008-08-22 | 2011-11-03 | Syngenta Crop Protection Llc | Insecticidal compounds |
| CN102143960A (zh) | 2008-09-04 | 2011-08-03 | 先正达参股股份有限公司 | 杀虫化合物 |
| RS58508B1 (sr) | 2008-11-14 | 2019-04-30 | Merial Inc | Enantiomerno obogaćena paraziticidalna jedinjenja ariloazol-2-il cijanoetilamino |
| CN102271672B (zh) | 2008-11-19 | 2015-02-04 | 梅里亚有限公司 | 用于治疗寄生物感染的包含单独的或与甲脒组合的1-芳基吡唑的组合物 |
| TWI457347B (zh) | 2008-12-04 | 2014-10-21 | Merial Ltd | 二聚合的阿佛菌素(avermectin)及密倍脈心(milbemycin)衍生物 |
| DK2424862T3 (en) | 2009-04-30 | 2014-12-15 | Basf Se | METHOD FOR PRODUCING SUBSTITUTED ISOXAZOLINFORBINDELSER AND THEIR Precursor |
| TWI487486B (zh) | 2009-12-01 | 2015-06-11 | Syngenta Participations Ag | 以異唑啉衍生物為主之殺蟲化合物 |
| UA108219C2 (uk) | 2009-12-17 | 2015-04-10 | Протипаразитарні дигідроазолові сполуки та композиція, яка їх містить (варіанти) | |
| EP2531506B1 (en) | 2010-02-05 | 2014-05-14 | Intervet International B.V. | Spiroindoline compounds for use as anthelminthics |
| UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
| MA34247B1 (fr) | 2010-05-27 | 2013-05-02 | Du Pont | Forme cristalline du 4-[5-[3-chloro-5-(trifluorométhyl) phényl] -4,5-dihydro-5-(trifluorométhyl)-3-isoxazolyl]-n-[2-oxo-2-[(2, 2,2-trifluoroéthyl) amino] éthyl]-1-naphtalènecarboxamide |
| CN102947279A (zh) | 2010-06-23 | 2013-02-27 | 巴斯夫欧洲公司 | 生产用于防治无脊椎动物害虫的亚胺化合物的方法 |
| WO2012007426A1 (en) | 2010-07-13 | 2012-01-19 | Basf Se | Azoline substituted isoxazoline benzamide compounds for combating animal pests |
| WO2012041872A1 (en) | 2010-09-29 | 2012-04-05 | Intervet International B.V. | N-heteroaryl compounds with cyclic bridging unit for the treatment of parasitic diseases |
| BR112013006030B1 (pt) | 2010-09-29 | 2020-03-17 | Intervet International B.V. | Composto e sais ou n-óxidos farmaceuticamente aceitáveis, e, uso do composto |
| WO2012059441A2 (en) | 2010-11-03 | 2012-05-10 | Basf Se | Method for preparing substituted isoxazoline compounds and their precursors 4-chloro, 4-bromo- or 4-iodobenzaldehyde oximes |
| JP2014028758A (ja) | 2010-11-19 | 2014-02-13 | Nissan Chem Ind Ltd | 寄生虫及び衛生害虫防除剤 |
| DE102010063691A1 (de) | 2010-12-21 | 2012-06-21 | Bayer Animal Health Gmbh | Ektoparasitizide Wirkstoffkombinationen |
| RU2602189C2 (ru) | 2010-12-27 | 2016-11-10 | Интервет Интернэшнл Б.В. | Изоксазолиновый состав, содержащий гликофурол для наружного и местного применения |
| CN105616406B (zh) | 2010-12-27 | 2019-12-13 | 英特维特国际股份有限公司 | 外用局部异噁唑啉制剂 |
| CN103717573B (zh) | 2011-06-27 | 2016-02-24 | 梅里亚股份有限公司 | 酰氨基-吡啶基醚化合物和组合物和它们对抗寄生物的用途 |
| WO2013017678A1 (en) | 2011-08-04 | 2013-02-07 | Intervet International B.V. | Novel spiroindoline compounds |
| DK3172964T3 (da) | 2011-09-12 | 2020-11-30 | Boehringer Ingelheim Animal Health Usa Inc | Parasitiske sammensætninger indeholdende et isoxazolinaktivstof, fremgangsmåde og anvendelser deraf |
| MX2014004743A (es) | 2011-10-19 | 2014-08-01 | Zoetis Llc | Uso de derivados de aminoacetonitrilo contra endoparasitos. |
| KR102066757B1 (ko) | 2011-11-17 | 2020-01-15 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 아릴 피라졸 및 치환된 이미다졸을 함유하는 조성물, 그의 방법 및 용도 |
| WO2013082373A1 (en) | 2011-12-02 | 2013-06-06 | Merial Limited | Long-acting injectable moxidectin formulations and novel moxidectin crystal forms |
| KR20140115329A (ko) * | 2011-12-23 | 2014-09-30 | 바스프 에스이 | 무척추동물 해충 퇴치를 위한 이소티아졸린 화합물 |
| EP2830615A1 (en) | 2012-03-28 | 2015-02-04 | Intervet International B.V. | Heteroaryl compounds with cyclic bridging unit for use in the treatment helminth infection |
| AU2013241853B2 (en) | 2012-03-28 | 2017-11-09 | Intervet International B.V. | Heteroaryl compounds with A-cyclic bridging unit |
| CN108685894B (zh) * | 2012-04-04 | 2022-04-26 | 英特维特国际股份有限公司 | 软咀嚼药用产品 |
| MX345971B (es) | 2012-04-20 | 2017-02-28 | Merial Ltd | Composiciones parasiticidas que comprenden derivados de benzimidazol, metodos y usos de los mismos. |
| AU2013245478A1 (en) * | 2012-11-01 | 2014-05-15 | Sumitomo Chemical Company, Limited | Method for administering agent for controlling ectoparasite to dog |
| AU2013348175B2 (en) | 2012-11-20 | 2016-11-17 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic compounds and compositions and method of using thereof |
| US9532946B2 (en) | 2012-11-20 | 2017-01-03 | Intervet Inc. | Manufacturing of semi-plastic pharmaceutical dosage units |
| AU2014342241B2 (en) | 2013-11-01 | 2017-09-14 | Boehringer Ingelheim Animal Health USA Inc. | Antiparasitic and pesticidal isoxazoline compounds |
| HUE046067T2 (hu) | 2013-12-10 | 2020-02-28 | Intervet Int Bv | Izoxazolin vegyületek felhasználása paraziták ellen |
| ES2971061T3 (es) | 2013-12-20 | 2024-06-03 | Intervet Int Bv | Composiciones de isoxazolina y uso de las mismas en la prevención o el tratamiento de infestaciones parasitarias en animales |
| HUE055444T2 (hu) | 2013-12-20 | 2021-11-29 | Intervet Int Bv | Izoxazolinszármazákok felhasználása baromfiak arthropodafertõzéseinek kezelésére vagy megelõzésére |
| CN106455560B (zh) | 2014-04-17 | 2020-12-22 | 勃林格殷格翰动物保健美国公司 | 用于保护动物免受寄生物的丙二腈化合物的用途 |
| CA2949511A1 (en) | 2014-05-19 | 2015-11-26 | Merial, Inc. | Anthelmintic compounds |
| ES2723969T3 (es) | 2014-06-19 | 2019-09-04 | Merial Inc | Composiciones parasiticidas que comprenden derivados de indol, procedimientos y usos de las mismas |
| EP3211998B1 (en) | 2014-10-31 | 2021-04-07 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal composition comprising fipronil |
| US20170348286A1 (en) | 2014-12-22 | 2017-12-07 | Intervet Inc. | Use of isoxazoline compounds for treating demodicosis |
| HUE059228T2 (hu) | 2015-06-23 | 2022-10-28 | Intervet Int Bv | E vitamint tartalmazó izoxazolin oldat, fertõtlenített ivóvízzel való felhasználásra |
| UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| AR111260A1 (es) | 2017-03-31 | 2019-06-19 | Intervet Int Bv | Formulación farmacéutica de la sal de crotonil amino piridina |
| US20210177808A1 (en) | 2017-11-07 | 2021-06-17 | Intervet Inc. | Injectable isoxazoline pharmaceutical compositions and their use against parasite infestation |
| BR112020008848A2 (pt) | 2017-11-07 | 2020-10-20 | Intervet International B.V. | processo de preparação de partículas de isoxazolina de tamanho grande |
| US11648238B2 (en) | 2017-12-12 | 2023-05-16 | Intervet Inc. | Implantable isoxazoline pharmaceutical compositions and uses thereof |
| AR113997A1 (es) | 2017-12-21 | 2020-07-08 | Intervet Int Bv | Composiciones antiparasitarias para unción dorsal continua |
| WO2019157241A1 (en) | 2018-02-08 | 2019-08-15 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof |
| TWI812673B (zh) * | 2018-02-12 | 2023-08-21 | 美商富曼西公司 | 用於防治無脊椎害蟲之萘異噁唑啉化合物 |
| WO2020002593A1 (en) | 2018-06-29 | 2020-01-02 | Intervet International B.V. | Compound for use against helminthic infection |
| WO2020150032A1 (en) | 2019-01-16 | 2020-07-23 | Boehringer Ingelheim Animal Health USA Inc. | Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof |
| WO2020180635A1 (en) | 2019-03-01 | 2020-09-10 | Boehringer Ingelheim Animal Health USA Inc. | Injectable clorsulon compositions, methods and uses thereof |
| WO2020201440A1 (en) * | 2019-04-03 | 2020-10-08 | Virbac | Low dose fluralaner compositions for protection against parasitic invertebrate pest |
| CA3138263A1 (en) | 2019-05-03 | 2020-11-12 | Intervet International B.V. | Injectable pharmaceutical compositions and uses thereof |
| AU2020316642B2 (en) | 2019-07-22 | 2025-10-23 | Intervet International B.V. | Soft chewable veterinary dosage form |
| CN114786484B (zh) | 2019-12-16 | 2024-11-19 | 英特维特国际股份有限公司 | 用于虱子控制的组合物 |
| WO2021122521A1 (en) | 2019-12-16 | 2021-06-24 | Intervet International B.V. | Composition for lice control in poultry |
| MX2022007308A (es) | 2019-12-16 | 2022-07-12 | Intervet Int Bv | Control parasitario en rumiantes. |
| CN120004816A (zh) * | 2019-12-18 | 2025-05-16 | 礼蓝动物保健有限公司 | 异噁唑啉衍生物 |
| ES2863583B2 (es) * | 2020-04-08 | 2022-02-15 | Univ Leon | Composicion veterinaria para rumiantes |
| WO2021233967A1 (en) | 2020-05-20 | 2021-11-25 | Intervet International B.V. | Injectable pharmaceutical compositions and uses thereof |
| AU2021278871A1 (en) | 2020-05-28 | 2023-01-19 | Boehringer Ingelheim Animal Health USA Inc. | Bi-modal release intra-ruminal capsule device and methods of use thereof |
| CN111909143B (zh) * | 2020-07-30 | 2021-10-29 | 山东省联合农药工业有限公司 | 一种异噁唑啉取代的苯甲酰胺类衍生物及其制备方法与用途 |
| US12161089B2 (en) | 2020-12-21 | 2024-12-10 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal collar comprising isoxazoline compounds |
| AU2022296860A1 (en) | 2021-06-25 | 2023-12-14 | Intervet International B.V. | Palatable veterinary compositions |
| WO2025027117A1 (en) | 2023-08-02 | 2025-02-06 | Intervet International B.V. | Carboxamide-4-quinoline compounds with anthelmintic activity |
| UA130006C2 (uk) | 2023-08-07 | 2025-10-08 | Юрій Юрійович Синиця | Водорозчинний комплекс афоксоланера, спосіб його отримання та ветеринарні протипаразитарні препарати, що його містять |
| CN119409654B (zh) * | 2023-08-18 | 2025-09-30 | 瑞普生物股份有限公司 | 一种异噁唑啉衍生物及其制备方法与应用 |
| WO2025191150A2 (en) | 2024-03-15 | 2025-09-18 | Krka, D.D., Novo Mesto | Stable isoxazoline formulation for topical application to the skin |
| WO2025218493A1 (zh) * | 2024-04-16 | 2025-10-23 | 南京派特美生科技有限公司 | 一种异噁唑啉类化合物及应用 |
Family Cites Families (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US431857A (en) | 1890-07-08 | Joseph d | ||
| US623912A (en) | 1899-04-25 | Charles j | ||
| GB331242A (en) | 1929-03-26 | 1930-06-26 | Joseph Harrison Thomson Robert | Improved means for driving kinematographs and sound recording or reproducing means in synchronism |
| US3984564A (en) | 1972-06-08 | 1976-10-05 | Sankyo Company Limited | Antibiotic substances B-41, their production and their use as insecticides and acaricides |
| US3950360A (en) | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
| US3968207A (en) * | 1973-12-10 | 1976-07-06 | American Cyanamid Company | Method of controlling fleas and ticks on cats and dogs |
| US3879532A (en) * | 1974-01-18 | 1975-04-22 | Shell Oil Co | Control by isoxazoles of endoparasitic nematodes |
| SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| US4129568A (en) * | 1977-05-12 | 1978-12-12 | Monsanto Company | 2-[3-Aryl-2-isoxazolin-5-yl]benzoates |
| US4199569A (en) | 1977-10-03 | 1980-04-22 | Merck & Co., Inc. | Selective hydrogenation products of C-076 compounds and derivatives thereof |
| DE3268413D1 (en) | 1981-09-03 | 1986-02-20 | Daikin Ind Ltd | Process for preparing chlorotrifluoromethylbenzene |
| US4820695A (en) | 1982-09-13 | 1989-04-11 | Eli Lilly And Company | C-20-dihydro-deoxy-(cyclic amino)-derivatives of macrolide antibiotics |
| IT1173213B (it) | 1984-02-03 | 1987-06-18 | Zambon Spa | Procedimento per fluorurare alcuni derivati dall'1l-fenil-2-ammino-1,3-propandiolo e loro intermedi |
| US5105009A (en) | 1983-06-02 | 1992-04-14 | Zambon S.P.A. | Intermediates for the preparation of 1-(phenyl)-1-hydroxy-2-amino-3-fluoropropane derivatives |
| US5332835A (en) | 1984-02-03 | 1994-07-26 | Zambon S.P.A. | Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process |
| US4582918A (en) | 1984-09-19 | 1986-04-15 | Schering Corporation | Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols |
| US4973750A (en) | 1984-09-19 | 1990-11-27 | Schering Corporation | Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols |
| ES8800986A1 (es) | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
| GB8523126D0 (en) | 1985-09-19 | 1985-10-23 | Ici Plc | Aryl pyridones |
| US4916154A (en) | 1986-09-12 | 1990-04-10 | American Cyanamid Company | 23-Imino derivatives of LL-F28249 compounds |
| US5227494A (en) | 1988-09-14 | 1993-07-13 | Schering Corporation | Process for preparing oxazoline compounds |
| US4876352A (en) | 1988-09-14 | 1989-10-24 | Schering Corporation | Pressurized fluorination of hydroxy alkyl groups |
| US5075320A (en) | 1989-01-04 | 1991-12-24 | Rehmert Chalmer V Jr | Method and composition for treating parasitic infestation of animals |
| IL98599A (en) | 1990-06-28 | 1995-06-29 | Merck & Co Inc | Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them |
| CA2094810C (en) | 1990-10-25 | 2002-06-04 | Jon E. Clark | Process for preparing florfenicol, its analogs and oxazoline intermediates thereto |
| JP2783912B2 (ja) | 1992-05-23 | 1998-08-06 | ノバルティス アクチェンゲゼルシャフト | 家畜内の蚤を駆除するための1−〔n−(ハロ−3−ピリジルメチル)〕−n−メチルアミノ−1−アルキルアミノ−2−ニトロエチレン誘導体 |
| US5352832A (en) | 1992-12-18 | 1994-10-04 | Schering Corporation | Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates |
| US5399717A (en) | 1993-09-29 | 1995-03-21 | Merck & Co., Inc. | Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1 |
| US5849736A (en) | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
| GB9505651D0 (en) | 1995-03-21 | 1995-05-10 | Agrevo Uk Ltd | AgrEvo UK Limited |
| CA2252543C (en) | 1996-04-26 | 2003-01-14 | Nippon Soda Co., Ltd. | Benzene derivatives substituted by heterocycles and herbicides |
| AR007292A1 (es) | 1996-06-06 | 1999-10-27 | Rohm & Haas | Compuestos aromaticos benciloxi sustituidos, una composicion fungicida, un metodo para controlar hongos fitopatogenicos y un metodo para controlarinsectos. |
| US5958888A (en) | 1996-07-02 | 1999-09-28 | Merial, Inc. | Water miscible macrolide solutions |
| US6271255B1 (en) | 1996-07-05 | 2001-08-07 | Biotica Technology Limited | Erythromycins and process for their preparation |
| FR2750861B1 (fr) * | 1996-07-11 | 1998-12-24 | Rhone Merieux | Procedes d'elimination des parasites, et notamment des ectoparasites de vertebres, notamment de mammiferes et compositions pour la mise en oeuvre de ce procede |
| US5663361A (en) | 1996-08-19 | 1997-09-02 | Schering Corporation | Process for preparing intermediates to florfenicol |
| US5932766A (en) | 1997-05-30 | 1999-08-03 | Abbott Laboratories | Process for the preparation of substituted keto-enamines |
| JP2003512290A (ja) | 1997-09-10 | 2003-04-02 | メルク エンド カムパニー インコーポレーテッド | 家畜抗菌剤としての8a−アザライド |
| US6339063B1 (en) | 1997-09-10 | 2002-01-15 | Merck & Co., Inc. | 9a-azalides as veterinary antimicrobial agents |
| AP9801420A0 (en) | 1998-01-02 | 1998-12-31 | Pfizer Prod Inc | Novel macrolides. |
| AU739393B2 (en) | 1998-03-19 | 2001-10-11 | Merck Sharp & Dohme Corp. | Sulfurpenta fluorophenyl pyrazoles for controlling ectoparasitic infestations |
| US6136838A (en) | 1998-03-19 | 2000-10-24 | Merck & Co., Inc. | Sulfurpentafluorophenylpyrazoles for controlling ectoparasitic infestations |
| US6140350A (en) | 1998-06-08 | 2000-10-31 | Sumitomo Chemical Company, Limited | Method for controlling ectoparasites |
| EP1119256B1 (en) | 1998-10-09 | 2003-06-04 | Novartis AG | Oral combination of lufenuron and nitenpyram against fleas |
| CA2292359C (en) | 1999-01-28 | 2004-09-28 | Pfizer Products Inc. | Novel azalides and methods of making same |
| EG22187A (en) | 1999-04-15 | 2002-10-31 | Aventis Cropscience Sa | New composition |
| GB2351081A (en) | 1999-06-18 | 2000-12-20 | Lilly Forschung Gmbh | Pharmaceutically active imidazoline compounds and analogues thereof |
| JP5046455B2 (ja) * | 1999-08-12 | 2012-10-10 | イーライ リリー アンド カンパニー | コンパニオン動物における害虫の経口処置 |
| ES2409630T3 (es) | 1999-12-02 | 2013-06-27 | Merial Limited | Control de artrópodos en animales |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| ATE243703T1 (de) | 2000-01-27 | 2003-07-15 | Pfizer Prod Inc | Antibiotische azalid-zusammensetzungen |
| DE10114597A1 (de) * | 2001-03-23 | 2002-10-02 | Bayer Cropscience Gmbh | Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
| CN100413879C (zh) | 2001-04-27 | 2008-08-27 | 辉瑞产品公司 | 4″-取代-9-脱氧-9a-氮杂-9a-高红霉素A衍生物的制备方法 |
| TW200724033A (en) | 2001-09-21 | 2007-07-01 | Du Pont | Anthranilamide arthropodicide treatment |
| JP2005538937A (ja) | 2002-03-08 | 2005-12-22 | シェーリング−プラウ, リミテッド | 新規なフロルフェニコール型抗生物質 |
| WO2004018410A1 (ja) * | 2002-08-26 | 2004-03-04 | Nissan Chemical Industries, Ltd. | 置換ベンズアニリド化合物及び有害生物防除剤 |
| US20040069235A1 (en) | 2002-09-27 | 2004-04-15 | Rasa Cordelia G. | Flea feeding apparatus |
| DE10320782A1 (de) | 2003-05-09 | 2004-11-25 | Bayer Cropscience Ag | Substituierte Oxyarene |
| TWI366442B (en) | 2003-07-30 | 2012-06-21 | Novartis Ag | Palatable ductile chewable veterinary composition |
| DE602004017347D1 (de) | 2003-11-04 | 2008-12-04 | Intervet Int Bv | Azol-pestiziden |
| GB0402677D0 (en) | 2003-11-06 | 2004-03-10 | Novartis Ag | Organic compounds |
| CA2550660C (en) | 2003-12-23 | 2011-03-15 | Schering-Plough Ltd. | Florfenicol prodrug having improved water solubility |
| WO2005066119A2 (en) | 2003-12-31 | 2005-07-21 | Schering-Plough Ltd. | Antibacterial 1-(4-mono-and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoropropanols and preparation thereof |
| BRPI0418328A (pt) | 2003-12-31 | 2007-05-02 | Schering Plough Ltd | controle de parasitas em animais pelo uso de derivados de imidazo [1,2-b]piridazina |
| JP2005272452A (ja) | 2004-02-23 | 2005-10-06 | Nissan Chem Ind Ltd | 置換ベンズアニリド化合物及び有害生物防除剤 |
| CN102558082B (zh) | 2004-03-05 | 2015-09-30 | 日产化学工业株式会社 | 异噁唑啉取代苯甲酰胺化合物的制备中间体 |
| JP2007530598A (ja) | 2004-03-26 | 2007-11-01 | サイトカイン・ファーマサイエンシズ・インコーポレーテッド | マクロファージ遊走阻害因子の阻害に関する、化合物、組成物、作製プロセス、および使用方法 |
| CA2574335C (en) | 2004-07-28 | 2013-10-01 | Intervet International B.V. | Veterinary composition comprising an arylpyrazole and a nitroenamine with antiparasitic activity |
| NZ553777A (en) | 2004-09-23 | 2010-11-26 | Schering Plough Ltd | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives |
| EP1842109A1 (en) | 2005-01-25 | 2007-10-10 | GCC IP Pty Limited | Toner detection window cleaning apparatus |
| JP5051340B2 (ja) | 2005-06-06 | 2012-10-17 | 日産化学工業株式会社 | 置換イソキサゾリン化合物及び有害生物防除剤 |
| EP1890547A2 (en) | 2005-06-09 | 2008-02-27 | Schering-Plough Ltd. | Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives |
| MY146795A (en) | 2005-06-09 | 2012-09-28 | Novartis Ag | Process for the synthesis of organic compounds |
| ES2443690T3 (es) | 2005-09-02 | 2014-02-20 | Nissan Chemical Industries, Ltd. | Compuesto de benzamida sustituido con isoxazolina y agente controlador de organismos dañinos |
| JP2007106756A (ja) | 2005-09-14 | 2007-04-26 | Nissan Chem Ind Ltd | 置換イソキサゾリン化合物及び有害生物防除剤 |
| TWI266597B (en) * | 2005-09-27 | 2006-11-11 | Delta Electronics Inc | Electronic apparatus capable of dissipating heat uniformly |
| US20090143410A1 (en) * | 2005-12-14 | 2009-06-04 | Kanu Maganbhai Patel | Isoxazolines for Controlling Invertebrate Pests |
| TW200803740A (en) * | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
| CN101346336B (zh) | 2005-12-26 | 2013-02-27 | 日产化学工业株式会社 | 1,3-二(取代苯基)-3-取代-2-丙烯-1-酮化合物和其盐 |
| TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
| BRPI0707091B8 (pt) * | 2006-03-10 | 2018-02-14 | Nissan Chemical Ind Ltd | composto de isoxalina e benzaldoxima substituído ou um sal do mesmo; pesticida, agroquímico, endo- ou ecto-parasiticidapara mamíferos ou pássaros, inseticida e acaricida contendo como um ou mais ingredientes ativos selecionados a partir do composto de isoxalina substituído e o sal do mesmo |
| BRPI0710403A2 (pt) | 2006-04-20 | 2011-08-09 | Du Pont | composto composição, composição de controle, de pulverização, de isca, dispositivo de armadilha, métodos de controle, métodos de proteção, semente tratada, composição de proteção |
| WO2007125984A1 (ja) | 2006-04-28 | 2007-11-08 | Nihon Nohyaku Co., Ltd. | イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法 |
| JP2008044880A (ja) | 2006-08-15 | 2008-02-28 | Bayer Cropscience Ag | 殺虫性イソオキサゾリン類 |
| EP2151437A4 (en) | 2007-03-07 | 2012-05-02 | Nissan Chemical Ind Ltd | ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT |
| WO2008122375A2 (en) | 2007-04-10 | 2008-10-16 | Bayer Cropscience Ag | Insecticidal aryl isoxazoline derivatives |
| CN101815706A (zh) * | 2007-06-13 | 2010-08-25 | 杜邦公司 | 异*唑啉杀昆虫剂 |
| TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
| MX368680B (es) | 2007-06-27 | 2019-10-11 | Du Pont | Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga. |
| US8952175B2 (en) * | 2007-06-27 | 2015-02-10 | Nissan Chemical Industries, Ltd. | Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound and method for production of isoxazoline compound |
| TWI600639B (zh) * | 2007-08-17 | 2017-10-01 | 杜邦股份有限公司 | 製備5-鹵烷基-4,5-二氫異唑衍生物之化合物 |
| TWI556741B (zh) | 2007-08-17 | 2016-11-11 | 英特威特國際股份有限公司 | 異唑啉組成物及其作為抗寄生蟲藥上的應用 |
| MX2010003557A (es) | 2007-10-03 | 2010-04-12 | Du Pont | Compuestos de isoxazolina de naftaleno para el control de plagas de invertebrados. |
| TWI518076B (zh) | 2008-04-09 | 2016-01-21 | 杜邦股份有限公司 | 製備雜環化合物之方法 |
-
2008
- 2008-06-26 MX MX2014010553A patent/MX368680B/es unknown
- 2008-06-26 DK DK15178198.6T patent/DK2957284T3/en active
- 2008-06-26 NO NO15178198A patent/NO2957284T3/no unknown
- 2008-06-26 CA CA2685072A patent/CA2685072C/en active Active
- 2008-06-26 PT PT87719787T patent/PT2182945E/pt unknown
- 2008-06-26 MX MX2015011173A patent/MX361762B/es unknown
- 2008-06-26 LT LTEP15178198.6T patent/LT2957284T/lt unknown
- 2008-06-26 JP JP2010515096A patent/JP6006471B2/ja active Active
- 2008-06-26 KR KR1020167030535A patent/KR101769728B1/ko active Active
- 2008-06-26 ES ES08771978.7T patent/ES2549731T3/es active Active
- 2008-06-26 BR BRPI0810929A patent/BRPI0810929B8/pt active IP Right Grant
- 2008-06-26 US US12/663,848 patent/US11278533B2/en active Active
- 2008-06-26 EP EP17206287.9A patent/EP3351243A1/en active Pending
- 2008-06-26 EP EP08771978.7A patent/EP2182945B1/en not_active Revoked
- 2008-06-26 PL PL15178198T patent/PL2957284T3/pl unknown
- 2008-06-26 PT PT151781986T patent/PT2957284T/pt unknown
- 2008-06-26 KR KR1020107001744A patent/KR101714059B1/ko active Active
- 2008-06-26 KR KR1020157020688A patent/KR101714291B1/ko active Active
- 2008-06-26 CA CA2971008A patent/CA2971008A1/en not_active Abandoned
- 2008-06-26 SI SI200831932T patent/SI2957284T1/en unknown
- 2008-06-26 CN CN200880019716A patent/CN101743000A/zh active Pending
- 2008-06-26 ES ES15178198.6T patent/ES2666187T3/es active Active
- 2008-06-26 SI SI200831504T patent/SI2182945T1/sl unknown
- 2008-06-26 MX MX2009013748A patent/MX2009013748A/es active IP Right Grant
- 2008-06-26 WO PCT/US2008/068268 patent/WO2009003075A1/en not_active Ceased
- 2008-06-26 RU RU2010102529/15A patent/RU2508102C2/ru not_active IP Right Cessation
- 2008-06-26 CN CN201610078394.1A patent/CN105640952A/zh active Pending
- 2008-06-26 EP EP15178198.6A patent/EP2957284B1/en not_active Revoked
- 2008-06-26 HU HUE15178198A patent/HUE037127T2/hu unknown
- 2008-06-26 DK DK08771978.7T patent/DK2182945T3/en active
- 2008-06-26 AU AU2008268321A patent/AU2008268321C1/en active Active
- 2008-06-26 HR HRP20150978TT patent/HRP20150978T1/hr unknown
-
2014
- 2014-10-20 JP JP2014213472A patent/JP6099610B2/ja active Active
-
2016
- 2016-06-22 JP JP2016123353A patent/JP6258410B2/ja active Active
- 2016-07-12 US US15/207,999 patent/US20160317520A1/en not_active Abandoned
- 2016-11-11 JP JP2016220118A patent/JP6167217B2/ja active Active
- 2016-12-06 HK HK16113909.5A patent/HK1225622A1/zh unknown
-
2017
- 2017-12-05 JP JP2017233023A patent/JP6411621B2/ja active Active
-
2018
- 2018-03-16 HR HRP20180453TT patent/HRP20180453T1/hr unknown
- 2018-03-19 CY CY20181100313T patent/CY1120038T1/el unknown
- 2018-08-07 HK HK18110143.5A patent/HK1250648A1/en unknown
- 2018-08-14 US US16/103,836 patent/US20180353494A1/en not_active Abandoned
- 2018-09-25 JP JP2018178283A patent/JP2019014728A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX368680B (es) | Administración subcutánea de un derivado de isoxazol-benzamida para usarse en un método para proteger un mamífero de una pulga. | |
| TW200738696A (en) | Isoxazolines for controlling invertebrate pests | |
| CY1123578T1 (el) | Ισοξαζολινες ναφθαλενιου ως παραγοντες καταπολεμησης ασπονδυλων επιβλαβων οργανισμων | |
| CO6311055A2 (es) | Composiciones pesticidas con al menos cuatro estructuras de anillo | |
| UA98116C2 (ru) | Изоксазолины, композиция, их применение, способы получения и промежуточные соединения | |
| WO2007070606A3 (en) | Isoxazolines for controlling invertebrate pests | |
| MX2016006685A (es) | Compuestos heterociclicos de n-acilimino. | |
| PE20141041A1 (es) | Compuestos, metodos y formulaciones parasiticidas | |
| AR073740A1 (es) | Compuestos para el tratamiento de la hepatitis c | |
| CO5590957A2 (es) | Amino-1,3,5-triazinas sustituidas en n con radicales biciclicos quirales, procedimiento para su preparacion, composiciones de las mismas y su uso como herbicidas y reguladores del crecimiento de las plantas | |
| CO6260136A2 (es) | Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxazol | |
| CO6140059A2 (es) | Derivados de imidazol-pirimidina para el tratamiento de enfermedades relacionadas con la glicogeno sintasa quinasa (gsk3) | |
| CA2494047A1 (en) | Method for preparing 3-halo-4,5-dihydro-1h-pyrazoles | |
| WO2007149448A3 (en) | Pyrazinones as cellular proliferation inhibitors | |
| AR083861A1 (es) | OXAZOLIDINONAS COMO MODULADORES DE mGluR5 Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN | |
| EA200200639A1 (ru) | 3-(4,5-дигидроизоксазол-5-ил)бензоилпиразолы | |
| RU2017131553A (ru) | 2-оксо-3, 4-дигидрохинолиновые соединения в качестве регуляторов роста растений | |
| CY1113042T1 (el) | Αντιμετωπιση μυϊασης | |
| EA200700767A1 (ru) | Способ получения пиразолов | |
| DK1072601T3 (da) | 4-Arylpiperidinderivater til behandling af pruritus | |
| DK1802581T3 (da) | 4-[(2,4-Dichlor-5-methoxyphenyl)amino]-6-alkoxy-7-ethynyl-3-quinolincarbonitriller til behandling af iskæmisk beskadigelse | |
| TW200716604A (en) | Carboxamide compound and use thereof | |
| DE60006029D1 (de) | 1-Aza-2-alkyl-6-aryl-cycloalkanen zur Verbesserung des Gedächtnisses | |
| CO6210741A2 (es) | Derivados insecticidas de bencilaminas sustituidas | |
| DK2264019T3 (da) | Mellemforbindelser til fremstilling af taxanderivater |