IT1228934B - Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici - Google Patents
Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori dupliciInfo
- Publication number
- IT1228934B IT1228934B IT8721697A IT2169787A IT1228934B IT 1228934 B IT1228934 B IT 1228934B IT 8721697 A IT8721697 A IT 8721697A IT 2169787 A IT2169787 A IT 2169787A IT 1228934 B IT1228934 B IT 1228934B
- Authority
- IT
- Italy
- Prior art keywords
- oxabicycid
- duplic
- eptan
- hydroxamic
- inhibitors
- Prior art date
Links
- NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/900,565 US4672075A (en) | 1986-08-26 | 1986-08-26 | 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8721697A0 IT8721697A0 (it) | 1987-08-24 |
IT1228934B true IT1228934B (it) | 1991-07-10 |
Family
ID=25412729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8721697A IT1228934B (it) | 1986-08-26 | 1987-08-24 | Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici |
Country Status (7)
Country | Link |
---|---|
US (1) | US4672075A (it) |
JP (1) | JPS6360988A (it) |
CA (1) | CA1301179C (it) |
DE (1) | DE3728350A1 (it) |
FR (1) | FR2603284B1 (it) |
GB (1) | GB2194531B (it) |
IT (1) | IT1228934B (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4707494A (en) * | 1986-08-26 | 1987-11-17 | E. R. Squibb & Sons, Inc. | 7-oxabicyclo(2.2.1)heptane compounds useful in the treatment of inflammation |
US4672075A (en) * | 1986-08-26 | 1987-06-09 | E. R. Squibb & Sons | 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents |
US5075330A (en) * | 1989-05-26 | 1991-12-24 | Warner-Lambert Co. | N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents |
US4981865A (en) * | 1989-05-26 | 1991-01-01 | Warner-Lambert Co. | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents |
US5112846A (en) * | 1989-05-26 | 1992-05-12 | Warner-Lambert Company | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents |
AU2010241567B2 (en) | 2009-04-29 | 2013-10-31 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical compositions comprising EPA and a cardiovascular agent and methods of using the same |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4254044A (en) * | 1977-11-04 | 1981-03-03 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds |
US4143054A (en) * | 1977-11-04 | 1979-03-06 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane- and 7-oxabicycloheptene compounds |
US4228180A (en) * | 1979-11-01 | 1980-10-14 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs |
JPS58113152A (ja) * | 1981-12-28 | 1983-07-05 | Ono Pharmaceut Co Ltd | 2−アミノフエノ−ル誘導体、その製造方法およびそれらを有効成分として含有する治療剤 |
US4497827A (en) * | 1982-08-30 | 1985-02-05 | Syntex (U.S.A.) Inc. | Arachidonic acid analogues as anti-inflammatory and anti-allergic agents |
US4582854A (en) * | 1983-03-14 | 1986-04-15 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted oxa prostaglandin analgos useful in the treatment of thrombolytic disease |
US4661506A (en) * | 1984-11-30 | 1987-04-28 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted ox prostaglandin analogs |
US4604407A (en) * | 1985-04-04 | 1986-08-05 | E. R. Squibb & Sons, Inc. | Hydroxamates |
US4672075A (en) * | 1986-08-26 | 1987-06-09 | E. R. Squibb & Sons | 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents |
-
1986
- 1986-08-26 US US06/900,565 patent/US4672075A/en not_active Expired - Fee Related
-
1987
- 1987-07-14 CA CA000541996A patent/CA1301179C/en not_active Expired - Lifetime
- 1987-07-28 GB GB8717818A patent/GB2194531B/en not_active Expired - Fee Related
- 1987-08-24 IT IT8721697A patent/IT1228934B/it active
- 1987-08-25 DE DE19873728350 patent/DE3728350A1/de not_active Withdrawn
- 1987-08-25 FR FR878711892A patent/FR2603284B1/fr not_active Expired - Fee Related
- 1987-08-26 JP JP62212627A patent/JPS6360988A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2603284A1 (fr) | 1988-03-04 |
DE3728350A1 (de) | 1988-03-03 |
FR2603284B1 (fr) | 1990-11-16 |
CA1301179C (en) | 1992-05-19 |
GB2194531A (en) | 1988-03-09 |
JPS6360988A (ja) | 1988-03-17 |
GB8717818D0 (en) | 1987-09-03 |
US4672075A (en) | 1987-06-09 |
GB2194531B (en) | 1990-07-18 |
IT8721697A0 (it) | 1987-08-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950830 |