IT8621143A0 - Derivati dell'acido malonico e metodi per la loro sintesi. - Google Patents
Derivati dell'acido malonico e metodi per la loro sintesi.Info
- Publication number
- IT8621143A0 IT8621143A0 IT8621143A IT2114386A IT8621143A0 IT 8621143 A0 IT8621143 A0 IT 8621143A0 IT 8621143 A IT8621143 A IT 8621143A IT 2114386 A IT2114386 A IT 2114386A IT 8621143 A0 IT8621143 A0 IT 8621143A0
- Authority
- IT
- Italy
- Prior art keywords
- synthesis
- derivatives
- methods
- malonic acid
- malonic
- Prior art date
Links
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical class OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21143/86A IT1196500B (it) | 1986-07-16 | 1986-07-16 | Derivati dell'acido malonico e metodi per la loro sintesi |
DE8787109318T DE3783280T2 (de) | 1986-07-16 | 1987-06-29 | Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
EP87109318A EP0253190B1 (en) | 1986-07-16 | 1987-06-29 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
DE8787109317T DE3784799T2 (de) | 1986-07-16 | 1987-06-29 | Malonsaeurederivate und ihre synthesemethoden. |
EP87109317A EP0254080B1 (en) | 1986-07-16 | 1987-06-29 | Malonic acid derivatives and methods for their synthesis |
ES87109317T ES2044874T3 (es) | 1986-07-16 | 1987-06-29 | Derivados del acido malonico y metodos para su sintesis. |
AT87109318T ATE84044T1 (de) | 1986-07-16 | 1987-06-29 | Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
ES87109318T ES2052517T3 (es) | 1986-07-16 | 1987-06-29 | Analogos de tuftsina parcialmente retroinversos, metodo de preparacion de los mismos y composiciones farmaceuticas que los contienen. |
AT87109317T ATE86964T1 (de) | 1986-07-16 | 1987-06-29 | Malonsaeurederivate und ihre synthesemethoden. |
CA000541630A CA1304539C (en) | 1986-07-16 | 1987-07-08 | Malonic acid derivatives and methods for their synthesis |
CA000541628A CA1318457C (en) | 1986-07-16 | 1987-07-08 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
US07/074,053 US4914226A (en) | 1986-07-16 | 1987-07-16 | Malonic acid derivatives and methods for their synthesis |
US07/074,054 US4816560A (en) | 1986-07-16 | 1987-07-16 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
JP62176063A JPS6323834A (ja) | 1986-07-16 | 1987-07-16 | マロン酸誘導体 |
JP62176064A JPH0832720B2 (ja) | 1986-07-16 | 1987-07-16 | タフトシン類似体、その製法及び医薬組成物 |
GR920403197T GR3007494T3 (it) | 1986-07-16 | 1993-03-30 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21143/86A IT1196500B (it) | 1986-07-16 | 1986-07-16 | Derivati dell'acido malonico e metodi per la loro sintesi |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8621143A0 true IT8621143A0 (it) | 1986-07-16 |
IT1196500B IT1196500B (it) | 1988-11-16 |
Family
ID=11177375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21143/86A IT1196500B (it) | 1986-07-16 | 1986-07-16 | Derivati dell'acido malonico e metodi per la loro sintesi |
Country Status (8)
Country | Link |
---|---|
US (1) | US4914226A (it) |
EP (1) | EP0254080B1 (it) |
JP (1) | JPS6323834A (it) |
AT (1) | ATE86964T1 (it) |
CA (1) | CA1304539C (it) |
DE (1) | DE3784799T2 (it) |
ES (1) | ES2044874T3 (it) |
IT (1) | IT1196500B (it) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02245277A (ja) * | 1989-03-20 | 1990-10-01 | Ntn Corp | 圧電素子を用いた加振装置 |
US5569745A (en) * | 1994-02-25 | 1996-10-29 | Resolution Pharmaceuticals Inc. | Peptide-Chelator conjugates |
US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
US6939873B2 (en) * | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
US7683071B2 (en) * | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
ES2315569T3 (es) | 2002-12-11 | 2009-04-01 | Taro Pharmaceutical Industries Ltd. | Procedimiento de tratamiento de trastornos del movimiento usando derivados de acido barbiturico. |
EP1781624A4 (en) * | 2004-07-02 | 2010-06-23 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 1-METHOXYMETHYL-5,5-DIPHENYLBARBITURIC ACID |
EP2081576A4 (en) * | 2006-11-14 | 2010-06-30 | Taro Pharmaceuticals North Ame | METHOD FOR IMPROVING BIOAVAILABILITY FOR NON-EDMING BARBITURATES |
US9828324B2 (en) | 2010-10-20 | 2017-11-28 | Sirrus, Inc. | Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom |
US9249265B1 (en) | 2014-09-08 | 2016-02-02 | Sirrus, Inc. | Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions |
US9279022B1 (en) | 2014-09-08 | 2016-03-08 | Sirrus, Inc. | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions |
WO2012054633A2 (en) | 2010-10-20 | 2012-04-26 | Bioformix, Llc | Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent |
US10414839B2 (en) | 2010-10-20 | 2019-09-17 | Sirrus, Inc. | Polymers including a methylene beta-ketoester and products formed therefrom |
EP3517523A1 (en) | 2011-10-19 | 2019-07-31 | Sirrus, Inc. | Multifunctional monomers and methods for making them |
EP2831124B1 (en) | 2012-03-30 | 2016-10-05 | Sirrus, Inc. | Composite and laminate articles and polymerizable systems for producing the same |
JP6188252B2 (ja) | 2012-03-30 | 2017-08-30 | シラス・インコーポレイテッド | 重合性組成物の活性化方法、重合系およびこれにより形成される製品 |
EP3626784A1 (en) | 2012-03-30 | 2020-03-25 | Sirrus, Inc. | Ink and coating formulations and polymerizable systems for producing the same |
WO2013181600A2 (en) | 2012-06-01 | 2013-12-05 | Bioformix Inc. | Optical material and articles formed therefrom |
WO2014078689A1 (en) | 2012-11-16 | 2014-05-22 | Bioformix Inc. | Plastics bonding systems and methods |
JP6549038B2 (ja) | 2012-11-30 | 2019-07-24 | シラス・インコーポレイテッド | エレクトロニクス適用のための複合組成物 |
CN105008321A (zh) | 2013-01-11 | 2015-10-28 | 瑟拉斯公司 | 经过双(羟甲基)丙二酸酯的途径获得亚甲基丙二酸酯的方法 |
US9416091B1 (en) | 2015-02-04 | 2016-08-16 | Sirrus, Inc. | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions |
US9315597B2 (en) | 2014-09-08 | 2016-04-19 | Sirrus, Inc. | Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures |
US10501400B2 (en) | 2015-02-04 | 2019-12-10 | Sirrus, Inc. | Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions |
US9334430B1 (en) | 2015-05-29 | 2016-05-10 | Sirrus, Inc. | Encapsulated polymerization initiators, polymerization systems and methods using the same |
US9217098B1 (en) | 2015-06-01 | 2015-12-22 | Sirrus, Inc. | Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound |
US9518001B1 (en) | 2016-05-13 | 2016-12-13 | Sirrus, Inc. | High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation |
US10196481B2 (en) | 2016-06-03 | 2019-02-05 | Sirrus, Inc. | Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof |
US9567475B1 (en) | 2016-06-03 | 2017-02-14 | Sirrus, Inc. | Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes |
US10428177B2 (en) | 2016-06-03 | 2019-10-01 | Sirrus, Inc. | Water absorbing or water soluble polymers, intermediate compounds, and methods thereof |
US9617377B1 (en) | 2016-06-03 | 2017-04-11 | Sirrus, Inc. | Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes |
WO2021060517A1 (ja) * | 2019-09-26 | 2021-04-01 | 味の素株式会社 | 有機物質の誘導体の製造方法、及び有機物質を含む試料の分析方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3013069A (en) * | 1958-07-15 | 1961-12-12 | American Cyanamid Co | 2-(substituted-benzyl)-1, 3-propane-dicarboxylic acids |
AR194578A1 (es) * | 1970-11-09 | 1973-07-31 | Kendall & Co | Un procedimiento para preparar acidos 5-sustituidos-5-fenilalquil barbituricos y un compuesto intermedio obtenido durante dicho procedimiento |
FR2211007A5 (it) * | 1972-12-15 | 1974-07-12 | Ugine Kuhlmann | |
IT1212508B (it) * | 1981-12-22 | 1989-11-22 | Anic Spa | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
IT1190891B (it) * | 1982-06-24 | 1988-02-24 | Anic Spa | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
ES2052517T3 (es) * | 1986-07-16 | 1994-07-16 | Eniricerche Spa | Analogos de tuftsina parcialmente retroinversos, metodo de preparacion de los mismos y composiciones farmaceuticas que los contienen. |
-
1986
- 1986-07-16 IT IT21143/86A patent/IT1196500B/it active
-
1987
- 1987-06-29 ES ES87109317T patent/ES2044874T3/es not_active Expired - Lifetime
- 1987-06-29 DE DE8787109317T patent/DE3784799T2/de not_active Expired - Fee Related
- 1987-06-29 AT AT87109317T patent/ATE86964T1/de not_active IP Right Cessation
- 1987-06-29 EP EP87109317A patent/EP0254080B1/en not_active Expired - Lifetime
- 1987-07-08 CA CA000541630A patent/CA1304539C/en not_active Expired - Lifetime
- 1987-07-16 US US07/074,053 patent/US4914226A/en not_active Expired - Fee Related
- 1987-07-16 JP JP62176063A patent/JPS6323834A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IT1196500B (it) | 1988-11-16 |
JPS6323834A (ja) | 1988-02-01 |
EP0254080B1 (en) | 1993-03-17 |
EP0254080A2 (en) | 1988-01-27 |
US4914226A (en) | 1990-04-03 |
ES2044874T3 (es) | 1994-01-16 |
DE3784799T2 (de) | 1993-06-24 |
DE3784799D1 (de) | 1993-04-22 |
EP0254080A3 (en) | 1989-05-31 |
CA1304539C (en) | 1992-06-30 |
ATE86964T1 (de) | 1993-04-15 |
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