IT8621143A0 - Derivati dell'acido malonico e metodi per la loro sintesi. - Google Patents
Derivati dell'acido malonico e metodi per la loro sintesi.Info
- Publication number
- IT8621143A0 IT8621143A0 IT8621143A IT2114386A IT8621143A0 IT 8621143 A0 IT8621143 A0 IT 8621143A0 IT 8621143 A IT8621143 A IT 8621143A IT 2114386 A IT2114386 A IT 2114386A IT 8621143 A0 IT8621143 A0 IT 8621143A0
- Authority
- IT
- Italy
- Prior art keywords
- synthesis
- derivatives
- methods
- malonic acid
- malonic
- Prior art date
Links
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical class OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21143/86A IT1196500B (it) | 1986-07-16 | 1986-07-16 | Derivati dell'acido malonico e metodi per la loro sintesi |
DE8787109317T DE3784799T2 (de) | 1986-07-16 | 1987-06-29 | Malonsaeurederivate und ihre synthesemethoden. |
DE8787109318T DE3783280T2 (de) | 1986-07-16 | 1987-06-29 | Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
ES87109317T ES2044874T3 (es) | 1986-07-16 | 1987-06-29 | Derivados del acido malonico y metodos para su sintesis. |
EP87109317A EP0254080B1 (en) | 1986-07-16 | 1987-06-29 | Malonic acid derivatives and methods for their synthesis |
ES87109318T ES2052517T3 (es) | 1986-07-16 | 1987-06-29 | Analogos de tuftsina parcialmente retroinversos, metodo de preparacion de los mismos y composiciones farmaceuticas que los contienen. |
AT87109317T ATE86964T1 (de) | 1986-07-16 | 1987-06-29 | Malonsaeurederivate und ihre synthesemethoden. |
AT87109318T ATE84044T1 (de) | 1986-07-16 | 1987-06-29 | Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
EP87109318A EP0253190B1 (en) | 1986-07-16 | 1987-06-29 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
CA000541628A CA1318457C (en) | 1986-07-16 | 1987-07-08 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
CA000541630A CA1304539C (en) | 1986-07-16 | 1987-07-08 | Malonic acid derivatives and methods for their synthesis |
JP62176064A JPH0832720B2 (ja) | 1986-07-16 | 1987-07-16 | タフトシン類似体、その製法及び医薬組成物 |
JP62176063A JPS6323834A (ja) | 1986-07-16 | 1987-07-16 | マロン酸誘導体 |
US07/074,054 US4816560A (en) | 1986-07-16 | 1987-07-16 | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
US07/074,053 US4914226A (en) | 1986-07-16 | 1987-07-16 | Malonic acid derivatives and methods for their synthesis |
GR920403197T GR3007494T3 (it) | 1986-07-16 | 1993-03-30 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT21143/86A IT1196500B (it) | 1986-07-16 | 1986-07-16 | Derivati dell'acido malonico e metodi per la loro sintesi |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8621143A0 true IT8621143A0 (it) | 1986-07-16 |
IT1196500B IT1196500B (it) | 1988-11-16 |
Family
ID=11177375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21143/86A IT1196500B (it) | 1986-07-16 | 1986-07-16 | Derivati dell'acido malonico e metodi per la loro sintesi |
Country Status (8)
Country | Link |
---|---|
US (1) | US4914226A (it) |
EP (1) | EP0254080B1 (it) |
JP (1) | JPS6323834A (it) |
AT (1) | ATE86964T1 (it) |
CA (1) | CA1304539C (it) |
DE (1) | DE3784799T2 (it) |
ES (1) | ES2044874T3 (it) |
IT (1) | IT1196500B (it) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02245277A (ja) * | 1989-03-20 | 1990-10-01 | Ntn Corp | 圧電素子を用いた加振装置 |
US5569745A (en) * | 1994-02-25 | 1996-10-29 | Resolution Pharmaceuticals Inc. | Peptide-Chelator conjugates |
US7683071B2 (en) * | 2000-07-26 | 2010-03-23 | Taro Pharmaceuticals Industries Ltd. | Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid |
US6939873B2 (en) * | 2000-07-26 | 2005-09-06 | Taro Pharmaceuticals Industries Limited | Non-sedating barbituric acid derivatives |
US6756379B2 (en) | 2001-07-26 | 2004-06-29 | Taro Pharmaceutical Industries Ltd. | Non-sedating barbiturate compounds as neuroprotective agents |
DE60324703D1 (de) | 2002-12-11 | 2008-12-24 | Taro Pharma Ind | Barbitursäure derivaten. |
EP1781624A4 (en) * | 2004-07-02 | 2010-06-23 | Taro Pharma Ind | PROCESS FOR THE PREPARATION OF 1-METHOXYMETHYL-5,5-DIPHENYLBARBITURIC ACID |
WO2008066704A2 (en) * | 2006-11-14 | 2008-06-05 | Taro Pharmaceuticals North America, Inc. | Method of improving bioavailability for non-sedating barbiturates |
US9249265B1 (en) | 2014-09-08 | 2016-02-02 | Sirrus, Inc. | Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions |
US10414839B2 (en) | 2010-10-20 | 2019-09-17 | Sirrus, Inc. | Polymers including a methylene beta-ketoester and products formed therefrom |
AU2011317067A1 (en) | 2010-10-20 | 2013-05-23 | Bioformix, Inc. | Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent |
US9279022B1 (en) | 2014-09-08 | 2016-03-08 | Sirrus, Inc. | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions |
US9828324B2 (en) | 2010-10-20 | 2017-11-28 | Sirrus, Inc. | Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom |
JP2014532625A (ja) | 2011-10-19 | 2014-12-08 | シラス・インコーポレイテッド | メチレンβ−ジケトンモノマー、メチレンβ−ジケトンモノマーを製造するための方法、これらから作られる重合可能な組成物および製品 |
US10913875B2 (en) | 2012-03-30 | 2021-02-09 | Sirrus, Inc. | Composite and laminate articles and polymerizable systems for producing the same |
US9234107B2 (en) | 2012-03-30 | 2016-01-12 | Sirrus, Inc. | Ink coating formulations and polymerizable systems for producing the same |
JP6188252B2 (ja) | 2012-03-30 | 2017-08-30 | シラス・インコーポレイテッド | 重合性組成物の活性化方法、重合系およびこれにより形成される製品 |
US10047192B2 (en) | 2012-06-01 | 2018-08-14 | Sirrus, Inc. | Optical material and articles formed therefrom |
CN105008438B (zh) | 2012-11-16 | 2019-10-22 | 拜奥福米克斯公司 | 塑料粘结体系及方法 |
CN105164797B (zh) | 2012-11-30 | 2019-04-19 | 瑟拉斯公司 | 用于电子应用的复合组合物 |
WO2014110388A1 (en) | 2013-01-11 | 2014-07-17 | Bioformix Inc. | Method to obtain methylene malonate via bis(hydroxymethyl) malonate pathway |
US9416091B1 (en) | 2015-02-04 | 2016-08-16 | Sirrus, Inc. | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions |
US9315597B2 (en) | 2014-09-08 | 2016-04-19 | Sirrus, Inc. | Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures |
US10501400B2 (en) | 2015-02-04 | 2019-12-10 | Sirrus, Inc. | Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions |
US9334430B1 (en) | 2015-05-29 | 2016-05-10 | Sirrus, Inc. | Encapsulated polymerization initiators, polymerization systems and methods using the same |
US9217098B1 (en) | 2015-06-01 | 2015-12-22 | Sirrus, Inc. | Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound |
US9518001B1 (en) | 2016-05-13 | 2016-12-13 | Sirrus, Inc. | High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation |
US9567475B1 (en) | 2016-06-03 | 2017-02-14 | Sirrus, Inc. | Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes |
US10196481B2 (en) | 2016-06-03 | 2019-02-05 | Sirrus, Inc. | Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof |
US9617377B1 (en) | 2016-06-03 | 2017-04-11 | Sirrus, Inc. | Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes |
US10428177B2 (en) | 2016-06-03 | 2019-10-01 | Sirrus, Inc. | Water absorbing or water soluble polymers, intermediate compounds, and methods thereof |
WO2021060517A1 (ja) * | 2019-09-26 | 2021-04-01 | 味の素株式会社 | 有機物質の誘導体の製造方法、及び有機物質を含む試料の分析方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3013069A (en) * | 1958-07-15 | 1961-12-12 | American Cyanamid Co | 2-(substituted-benzyl)-1, 3-propane-dicarboxylic acids |
AR194578A1 (es) * | 1970-11-09 | 1973-07-31 | Kendall & Co | Un procedimiento para preparar acidos 5-sustituidos-5-fenilalquil barbituricos y un compuesto intermedio obtenido durante dicho procedimiento |
FR2211007A5 (it) * | 1972-12-15 | 1974-07-12 | Ugine Kuhlmann | |
IT1212508B (it) * | 1981-12-22 | 1989-11-22 | Anic Spa | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
IT1190891B (it) * | 1982-06-24 | 1988-02-24 | Anic Spa | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
EP0253190B1 (en) * | 1986-07-16 | 1992-12-30 | ENIRICERCHE S.p.A. | Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them |
-
1986
- 1986-07-16 IT IT21143/86A patent/IT1196500B/it active
-
1987
- 1987-06-29 AT AT87109317T patent/ATE86964T1/de not_active IP Right Cessation
- 1987-06-29 ES ES87109317T patent/ES2044874T3/es not_active Expired - Lifetime
- 1987-06-29 EP EP87109317A patent/EP0254080B1/en not_active Expired - Lifetime
- 1987-06-29 DE DE8787109317T patent/DE3784799T2/de not_active Expired - Fee Related
- 1987-07-08 CA CA000541630A patent/CA1304539C/en not_active Expired - Lifetime
- 1987-07-16 US US07/074,053 patent/US4914226A/en not_active Expired - Fee Related
- 1987-07-16 JP JP62176063A patent/JPS6323834A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DE3784799D1 (de) | 1993-04-22 |
EP0254080A3 (en) | 1989-05-31 |
ES2044874T3 (es) | 1994-01-16 |
EP0254080A2 (en) | 1988-01-27 |
CA1304539C (en) | 1992-06-30 |
JPS6323834A (ja) | 1988-02-01 |
DE3784799T2 (de) | 1993-06-24 |
IT1196500B (it) | 1988-11-16 |
EP0254080B1 (en) | 1993-03-17 |
ATE86964T1 (de) | 1993-04-15 |
US4914226A (en) | 1990-04-03 |
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