ATE86964T1 - Malonsaeurederivate und ihre synthesemethoden. - Google Patents

Malonsaeurederivate und ihre synthesemethoden.

Info

Publication number
ATE86964T1
ATE86964T1 AT87109317T AT87109317T ATE86964T1 AT E86964 T1 ATE86964 T1 AT E86964T1 AT 87109317 T AT87109317 T AT 87109317T AT 87109317 T AT87109317 T AT 87109317T AT E86964 T1 ATE86964 T1 AT E86964T1
Authority
AT
Austria
Prior art keywords
acid derivatives
malonic acid
ornithine
cysteine
tyrosine
Prior art date
Application number
AT87109317T
Other languages
English (en)
Inventor
Trapani Romano Di
Antonio Silvio Verdini
Original Assignee
Eniricerche Spa
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa, Sclavo Spa filed Critical Eniricerche Spa
Application granted granted Critical
Publication of ATE86964T1 publication Critical patent/ATE86964T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT87109317T 1986-07-16 1987-06-29 Malonsaeurederivate und ihre synthesemethoden. ATE86964T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21143/86A IT1196500B (it) 1986-07-16 1986-07-16 Derivati dell'acido malonico e metodi per la loro sintesi
EP87109317A EP0254080B1 (de) 1986-07-16 1987-06-29 Malonsäurederivate und ihre Synthesemethoden

Publications (1)

Publication Number Publication Date
ATE86964T1 true ATE86964T1 (de) 1993-04-15

Family

ID=11177375

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87109317T ATE86964T1 (de) 1986-07-16 1987-06-29 Malonsaeurederivate und ihre synthesemethoden.

Country Status (8)

Country Link
US (1) US4914226A (de)
EP (1) EP0254080B1 (de)
JP (1) JPS6323834A (de)
AT (1) ATE86964T1 (de)
CA (1) CA1304539C (de)
DE (1) DE3784799T2 (de)
ES (1) ES2044874T3 (de)
IT (1) IT1196500B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02245277A (ja) * 1989-03-20 1990-10-01 Ntn Corp 圧電素子を用いた加振装置
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates
US7683071B2 (en) * 2000-07-26 2010-03-23 Taro Pharmaceuticals Industries Ltd. Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
US6756379B2 (en) 2001-07-26 2004-06-29 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
US6939873B2 (en) * 2000-07-26 2005-09-06 Taro Pharmaceuticals Industries Limited Non-sedating barbituric acid derivatives
AR042444A1 (es) * 2002-12-11 2005-06-22 Taro Pharmaceuticals Ireland L Metodo para el tratamiento de desordenes del movimiento mediante la utilizacion de acido barbiturico
CA2572797A1 (en) * 2004-07-02 2006-01-12 Daniella Gutman A process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid
US20080132529A1 (en) * 2006-11-14 2008-06-05 Avraham Yacobi Method of improving bioavailability for non-sedating barbiturates
US9249265B1 (en) 2014-09-08 2016-02-02 Sirrus, Inc. Emulsion polymers including one or more 1,1-disubstituted alkene compounds, emulsion methods, and polymer compositions
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US9828324B2 (en) 2010-10-20 2017-11-28 Sirrus, Inc. Methylene beta-diketone monomers, methods for making methylene beta-diketone monomers, polymerizable compositions and products formed therefrom
US9279022B1 (en) 2014-09-08 2016-03-08 Sirrus, Inc. Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions
SG189937A1 (en) 2010-10-20 2013-06-28 Bioformix Inc Synthesis of methylene malonates using rapid recovery in the presence of a heat transfer agent
JP6267643B2 (ja) 2011-10-19 2018-01-24 シラス・インコーポレイテッド 多官能性モノマー、多官能性モノマーを製造する方法、これらから形成された重合性組成物および製品
WO2013149173A1 (en) 2012-03-30 2013-10-03 Bioformix Inc. Ink and coating formulations and polymerizable systems for producing the same
EP2831125B1 (de) 2012-03-30 2016-10-05 Sirrus, Inc. Verfahren zur aktivierung von polymerisierbaren zusammensetzungen, polymerisierbare systeme und damit hergestellte produkte
EP2831124B1 (de) 2012-03-30 2016-10-05 Sirrus, Inc. Zusammengesetzte und laminierte artikel sowie polymerisierbare systeme zur herstellung davon
WO2013181600A2 (en) 2012-06-01 2013-12-05 Bioformix Inc. Optical material and articles formed therefrom
EP2920231B1 (de) 2012-11-16 2020-05-06 Sirrus, Inc. Kunststoffverbindungssysteme und verfahren
JP6549038B2 (ja) 2012-11-30 2019-07-24 シラス・インコーポレイテッド エレクトロニクス適用のための複合組成物
EP2943462B1 (de) 2013-01-11 2018-06-27 Sirrus, Inc. Verfahren zur gewinnung von methylenmalonat über bis(hydroxymethyl)malonat-weg
US9416091B1 (en) 2015-02-04 2016-08-16 Sirrus, Inc. Catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9315597B2 (en) 2014-09-08 2016-04-19 Sirrus, Inc. Compositions containing 1,1-disubstituted alkene compounds for preparing polymers having enhanced glass transition temperatures
US10501400B2 (en) 2015-02-04 2019-12-10 Sirrus, Inc. Heterogeneous catalytic transesterification of ester compounds with groups reactive under transesterification conditions
US9334430B1 (en) 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
US9518001B1 (en) 2016-05-13 2016-12-13 Sirrus, Inc. High purity 1,1-dicarbonyl substituted-1-alkenes and methods for their preparation
US9567475B1 (en) 2016-06-03 2017-02-14 Sirrus, Inc. Coatings containing polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US9617377B1 (en) 2016-06-03 2017-04-11 Sirrus, Inc. Polyester macromers containing 1,1-dicarbonyl-substituted 1 alkenes
US10196481B2 (en) 2016-06-03 2019-02-05 Sirrus, Inc. Polymer and other compounds functionalized with terminal 1,1-disubstituted alkene monomer(s) and methods thereof
US10428177B2 (en) 2016-06-03 2019-10-01 Sirrus, Inc. Water absorbing or water soluble polymers, intermediate compounds, and methods thereof
KR20220069949A (ko) * 2019-09-26 2022-05-27 아지노모토 가부시키가이샤 유기 물질의 유도체의 제조방법 및 유기 물질을 포함하는 시료의 분석 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3013069A (en) * 1958-07-15 1961-12-12 American Cyanamid Co 2-(substituted-benzyl)-1, 3-propane-dicarboxylic acids
AR194578A1 (es) * 1970-11-09 1973-07-31 Kendall & Co Un procedimiento para preparar acidos 5-sustituidos-5-fenilalquil barbituricos y un compuesto intermedio obtenido durante dicho procedimiento
FR2211007A5 (de) * 1972-12-15 1974-07-12 Ugine Kuhlmann
IT1212508B (it) * 1981-12-22 1989-11-22 Anic Spa Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
IT1190891B (it) * 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
DE3783280T2 (de) * 1986-07-16 1993-05-06 Eniricerche Spa Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.

Also Published As

Publication number Publication date
ES2044874T3 (es) 1994-01-16
EP0254080B1 (de) 1993-03-17
EP0254080A2 (de) 1988-01-27
IT8621143A0 (it) 1986-07-16
DE3784799D1 (de) 1993-04-22
JPS6323834A (ja) 1988-02-01
IT1196500B (it) 1988-11-16
DE3784799T2 (de) 1993-06-24
US4914226A (en) 1990-04-03
CA1304539C (en) 1992-06-30
EP0254080A3 (en) 1989-05-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee