SE8401398L - 7-oxabicykloheptansubstituerade prostaglandinanaloger - Google Patents
7-oxabicykloheptansubstituerade prostaglandinanalogerInfo
- Publication number
- SE8401398L SE8401398L SE8401398A SE8401398A SE8401398L SE 8401398 L SE8401398 L SE 8401398L SE 8401398 A SE8401398 A SE 8401398A SE 8401398 A SE8401398 A SE 8401398A SE 8401398 L SE8401398 L SE 8401398L
- Authority
- SE
- Sweden
- Prior art keywords
- prostaglandin analogs
- oxabicycloheptan
- substituted prostaglandin
- image
- alkyl
- Prior art date
Links
- DYWAPFDKPAHSED-UHFFFAOYSA-N 2-cycloheptyloxepane Chemical group C1CCCCCC1C1OCCCCC1 DYWAPFDKPAHSED-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003180 prostaglandins Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229940125692 cardiovascular agent Drugs 0.000 abstract 1
- 239000002327 cardiovascular agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000005356 cycloalkylalkenyl group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- FYFFGSSZFBZTAH-UHFFFAOYSA-N methylaminomethanetriol Chemical compound CNC(O)(O)O FYFFGSSZFBZTAH-UHFFFAOYSA-N 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
- 230000002537 thrombolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/474,913 US4474803A (en) | 1983-03-14 | 1983-03-14 | 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction |
| US52332083A | 1983-08-15 | 1983-08-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8401398D0 SE8401398D0 (sv) | 1984-03-13 |
| SE8401398L true SE8401398L (sv) | 1984-09-15 |
Family
ID=27044617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8401398A SE8401398L (sv) | 1983-03-14 | 1984-03-13 | 7-oxabicykloheptansubstituerade prostaglandinanaloger |
Country Status (24)
| Country | Link |
|---|---|
| KR (1) | KR840009085A (sv) |
| AT (1) | AT383600B (sv) |
| AU (1) | AU567919B2 (sv) |
| CA (1) | CA1256887A (sv) |
| CH (1) | CH658247A5 (sv) |
| DD (1) | DD216932A5 (sv) |
| DE (1) | DE3409124A1 (sv) |
| DK (1) | DK155584A (sv) |
| ES (1) | ES530548A0 (sv) |
| FI (1) | FI841008A (sv) |
| FR (1) | FR2542743B1 (sv) |
| GB (1) | GB2136428B (sv) |
| GR (1) | GR79881B (sv) |
| HU (1) | HU190530B (sv) |
| IE (1) | IE57027B1 (sv) |
| IL (1) | IL71184A0 (sv) |
| IT (1) | IT1173442B (sv) |
| LU (1) | LU85249A1 (sv) |
| NL (1) | NL8400797A (sv) |
| NO (1) | NO840960L (sv) |
| NZ (1) | NZ207361A (sv) |
| PL (1) | PL246663A1 (sv) |
| PT (1) | PT78242B (sv) |
| SE (1) | SE8401398L (sv) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513103A (en) * | 1983-10-21 | 1985-04-23 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease |
| US4526900A (en) * | 1984-01-26 | 1985-07-02 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4560698A (en) * | 1984-06-04 | 1985-12-24 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease |
| US4661506A (en) * | 1984-11-30 | 1987-04-28 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted ox prostaglandin analogs |
| US4588743A (en) * | 1985-01-22 | 1986-05-13 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4607049A (en) * | 1985-04-22 | 1986-08-19 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease |
| US4608386A (en) * | 1985-04-26 | 1986-08-26 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases |
| US4611006A (en) * | 1985-06-28 | 1986-09-09 | E. R. Squibb & Sons, Inc. | 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease |
| US4654356A (en) * | 1985-08-01 | 1987-03-31 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs |
| US4673685A (en) * | 1986-07-23 | 1987-06-16 | E. R. Squibb & Sons, Inc. | Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4143054A (en) * | 1977-11-04 | 1979-03-06 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane- and 7-oxabicycloheptene compounds |
| ZA829068B (en) * | 1980-07-01 | 1983-02-23 | Nat Res Dev | Prostaglandins |
| EP0082646B1 (en) * | 1981-12-23 | 1989-11-15 | National Research Development Corporation | Prostaglandins |
| US4549030A (en) * | 1982-12-13 | 1985-10-22 | The Upjohn Company | Organic compounds and process |
| US4526900A (en) * | 1984-01-26 | 1985-07-02 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
| US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
-
1984
- 1984-03-01 CA CA000448662A patent/CA1256887A/en not_active Expired
- 1984-03-02 NZ NZ207361A patent/NZ207361A/en unknown
- 1984-03-02 AU AU25235/84A patent/AU567919B2/en not_active Ceased
- 1984-03-05 IE IE525/84A patent/IE57027B1/xx unknown
- 1984-03-06 GR GR73998A patent/GR79881B/el unknown
- 1984-03-08 GB GB08406100A patent/GB2136428B/en not_active Expired
- 1984-03-08 IL IL71184A patent/IL71184A0/xx unknown
- 1984-03-13 AT AT0083484A patent/AT383600B/de not_active IP Right Cessation
- 1984-03-13 DK DK155584A patent/DK155584A/da not_active IP Right Cessation
- 1984-03-13 DE DE19843409124 patent/DE3409124A1/de not_active Withdrawn
- 1984-03-13 NL NL8400797A patent/NL8400797A/nl not_active Application Discontinuation
- 1984-03-13 CH CH1244/84A patent/CH658247A5/fr not_active IP Right Cessation
- 1984-03-13 FI FI841008A patent/FI841008A/fi not_active Application Discontinuation
- 1984-03-13 KR KR1019840001248A patent/KR840009085A/ko not_active Application Discontinuation
- 1984-03-13 PT PT78242A patent/PT78242B/pt unknown
- 1984-03-13 NO NO840960A patent/NO840960L/no unknown
- 1984-03-13 SE SE8401398A patent/SE8401398L/sv not_active Application Discontinuation
- 1984-03-13 ES ES530548A patent/ES530548A0/es active Granted
- 1984-03-13 FR FR8403835A patent/FR2542743B1/fr not_active Expired
- 1984-03-13 HU HU841001A patent/HU190530B/hu unknown
- 1984-03-14 LU LU85249A patent/LU85249A1/fr unknown
- 1984-03-14 DD DD84260892A patent/DD216932A5/de unknown
- 1984-03-14 PL PL24666384A patent/PL246663A1/xx unknown
- 1984-03-14 IT IT20049/84A patent/IT1173442B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| GB8406100D0 (en) | 1984-04-11 |
| DK155584A (da) | 1984-09-15 |
| NZ207361A (en) | 1986-12-05 |
| NL8400797A (nl) | 1984-10-01 |
| ES8506270A1 (es) | 1985-07-01 |
| AT383600B (de) | 1987-07-27 |
| DD216932A5 (de) | 1985-01-02 |
| FI841008A0 (fi) | 1984-03-13 |
| IE57027B1 (en) | 1992-03-25 |
| IE840525L (en) | 1984-09-14 |
| FR2542743B1 (fr) | 1987-10-30 |
| SE8401398D0 (sv) | 1984-03-13 |
| AU2523584A (en) | 1984-09-20 |
| FR2542743A1 (fr) | 1984-09-21 |
| IL71184A0 (en) | 1984-06-29 |
| FI841008A (fi) | 1984-09-15 |
| LU85249A1 (fr) | 1984-11-14 |
| CA1256887A (en) | 1989-07-04 |
| KR840009085A (ko) | 1984-12-24 |
| ES530548A0 (es) | 1985-07-01 |
| GB2136428B (en) | 1986-09-10 |
| DE3409124A1 (de) | 1984-09-27 |
| IT8420049A0 (it) | 1984-03-14 |
| PL246663A1 (en) | 1985-03-26 |
| AU567919B2 (en) | 1987-12-10 |
| PT78242B (en) | 1986-05-27 |
| NO840960L (no) | 1984-09-17 |
| GR79881B (sv) | 1984-10-31 |
| GB2136428A (en) | 1984-09-19 |
| DK155584D0 (da) | 1984-03-13 |
| HUT34179A (en) | 1985-02-28 |
| CH658247A5 (fr) | 1986-10-31 |
| HU190530B (en) | 1986-09-29 |
| IT1173442B (it) | 1987-06-24 |
| PT78242A (en) | 1984-04-01 |
| ATA83484A (de) | 1986-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI93351C (sv) | Förfarande för framställning av terapeutiskt användbara polyetylenglykolkarbaminater | |
| DE3370478D1 (en) | Isoquinolinesulfonamide derivatives and process for the preparation thereof | |
| SE8401398L (sv) | 7-oxabicykloheptansubstituerade prostaglandinanaloger | |
| SE503618C2 (sv) | Antihyperkolesterolemiska tetrazolföreningar | |
| CA1262138C (en) | PROSTAGLANDIN TETRAHYDROTHIENYL SUBSTITUTE ANALOGS | |
| EP0164987A3 (en) | 7-oxabicycloheptane substituted prostaglandin analogs | |
| BE899134A (fr) | Analogues de protaglandines a substituant 7-oxabicycloheptane, a proprietes therapeutiques. | |
| FR2445318A1 (fr) | Procede de preparation de 1-(3-mercapto-propanoyl)-l-prolines | |
| CA1267150C (en) | THIABICYCLOHEPTANE SUBSTITUTION DERIVATIVES OF AMINO-PROSTAGLANDIN ANALOGS | |
| CA1266668C (en) | OXAPROSTAGLANDIN ANALOG DERIVATIVES WITH 7-OXABICYCLOHEPTANE SUBSTITUTION | |
| EP0205857A3 (en) | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs | |
| PT86713A (pt) | Process for preparing an insecticidal composition containing thionophosphonoesters and a starting material | |
| CA1262912C (en) | TETRAHYDROFURANYLIC SUBSTITUTION DERIVATIVES OF PROSTAGLANDIN ANALOGS | |
| CA1267906C (en) | PROSTAGLANDIN ANALOGS WITH 7-OXABICYCLOHEPTANE SUBSTITUTE | |
| CA1268468C (en) | PROSTAGLANDIN ANALOGS WITH SUBSTITUTE THIABICYCLOHEPTAN GROUP | |
| FR2442235A1 (fr) | Analogues et intermediaires de prostacyclines | |
| SE8803765D0 (sv) | Nya isopolypeptider samt foerfarande foer framstaellning av desamma | |
| FR2398738A1 (fr) | Preparation de benzoylurees | |
| FR2453159A1 (fr) | Procede de preparation de 2-aminopyrazines substituees | |
| SE8204791D0 (sv) | Process for preparing alkoxy-vincaminic acid esters and alkoxy-apovincaminic acid esters | |
| DE3479421D1 (de) | Dibenzopyran derivatives | |
| DE59403903D1 (de) | Verfahren zur Herstellung von gegebenfalls 2-substituierten 5-Chlorimidazolen | |
| FR2389634A1 (sv) | ||
| FR2355813A1 (fr) | Procede de preparation de n-(2-cyanophenyl)-formiamidines | |
| CA1271198C (en) | 5,6-EPOXY-7-OXABICYCLOPTANE SUBSTITUTION DERIVATIVES OF PROSTAGLANDIN ANALOGS |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8401398-6 Effective date: 19910927 Format of ref document f/p: F |