PT78242B - Process for preparing 7-oxabicycloheptane substituted prostaglandin analogs - Google Patents
Process for preparing 7-oxabicycloheptane substituted prostaglandin analogsInfo
- Publication number
- PT78242B PT78242B PT78242A PT7824284A PT78242B PT 78242 B PT78242 B PT 78242B PT 78242 A PT78242 A PT 78242A PT 7824284 A PT7824284 A PT 7824284A PT 78242 B PT78242 B PT 78242B
- Authority
- PT
- Portugal
- Prior art keywords
- preparing
- prostaglandin analogs
- substituted prostaglandin
- oxabicycloheptane substituted
- oxabicycloheptane
- Prior art date
Links
- DYWAPFDKPAHSED-UHFFFAOYSA-N 2-cycloheptyloxepane Chemical group C1CCCCCC1C1OCCCCC1 DYWAPFDKPAHSED-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/474,913 US4474803A (en) | 1983-03-14 | 1983-03-14 | 7-Oxabicycloheptane substituted thio prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction |
US52332083A | 1983-08-15 | 1983-08-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT78242A PT78242A (en) | 1984-04-01 |
PT78242B true PT78242B (en) | 1986-05-27 |
Family
ID=27044617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT78242A PT78242B (en) | 1983-03-14 | 1984-03-13 | Process for preparing 7-oxabicycloheptane substituted prostaglandin analogs |
Country Status (24)
Country | Link |
---|---|
KR (1) | KR840009085A (en) |
AT (1) | AT383600B (en) |
AU (1) | AU567919B2 (en) |
CA (1) | CA1256887A (en) |
CH (1) | CH658247A5 (en) |
DD (1) | DD216932A5 (en) |
DE (1) | DE3409124A1 (en) |
DK (1) | DK155584A (en) |
ES (1) | ES530548A0 (en) |
FI (1) | FI841008A (en) |
FR (1) | FR2542743B1 (en) |
GB (1) | GB2136428B (en) |
GR (1) | GR79881B (en) |
HU (1) | HU190530B (en) |
IE (1) | IE57027B1 (en) |
IL (1) | IL71184A0 (en) |
IT (1) | IT1173442B (en) |
LU (1) | LU85249A1 (en) |
NL (1) | NL8400797A (en) |
NO (1) | NO840960L (en) |
NZ (1) | NZ207361A (en) |
PL (1) | PL246663A1 (en) |
PT (1) | PT78242B (en) |
SE (1) | SE8401398L (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4513103A (en) * | 1983-10-21 | 1985-04-23 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease |
US4526900A (en) * | 1984-01-26 | 1985-07-02 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
US4560698A (en) * | 1984-06-04 | 1985-12-24 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted thio prostaglandin analogs and their use in the treatment in thrombolytic disease |
US4661506A (en) * | 1984-11-30 | 1987-04-28 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted ox prostaglandin analogs |
US4588743A (en) * | 1985-01-22 | 1986-05-13 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
US4607049A (en) * | 1985-04-22 | 1986-08-19 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease |
US4608386A (en) * | 1985-04-26 | 1986-08-26 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases |
US4611006A (en) * | 1985-06-28 | 1986-09-09 | E. R. Squibb & Sons, Inc. | 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease |
US4654356A (en) * | 1985-08-01 | 1987-03-31 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs |
US4673685A (en) * | 1986-07-23 | 1987-06-16 | E. R. Squibb & Sons, Inc. | Hydroximic acids of 7-oxabicycloheptane substituted ethers and thioethers useful in the treatment of thrombotic disease |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4143054A (en) * | 1977-11-04 | 1979-03-06 | E. R. Squibb & Sons, Inc. | 7-oxabicycloheptane- and 7-oxabicycloheptene compounds |
ZA814307B (en) * | 1980-07-01 | 1983-02-23 | Nat Res Dev | Prostaglandins |
DE3280020D1 (en) * | 1981-12-23 | 1989-12-21 | Nat Res Dev | Prostaglandins |
US4549030A (en) * | 1982-12-13 | 1985-10-22 | The Upjohn Company | Organic compounds and process |
US4526900A (en) * | 1984-01-26 | 1985-07-02 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
US4542157A (en) * | 1984-04-27 | 1985-09-17 | E. R. Squibb & Sons, Inc. | 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease |
-
1984
- 1984-03-01 CA CA000448662A patent/CA1256887A/en not_active Expired
- 1984-03-02 AU AU25235/84A patent/AU567919B2/en not_active Ceased
- 1984-03-02 NZ NZ207361A patent/NZ207361A/en unknown
- 1984-03-05 IE IE525/84A patent/IE57027B1/en unknown
- 1984-03-06 GR GR73998A patent/GR79881B/el unknown
- 1984-03-08 GB GB08406100A patent/GB2136428B/en not_active Expired
- 1984-03-08 IL IL71184A patent/IL71184A0/en unknown
- 1984-03-13 DE DE19843409124 patent/DE3409124A1/en not_active Withdrawn
- 1984-03-13 AT AT0083484A patent/AT383600B/en not_active IP Right Cessation
- 1984-03-13 NL NL8400797A patent/NL8400797A/en not_active Application Discontinuation
- 1984-03-13 KR KR1019840001248A patent/KR840009085A/en not_active Application Discontinuation
- 1984-03-13 DK DK155584A patent/DK155584A/en not_active IP Right Cessation
- 1984-03-13 PT PT78242A patent/PT78242B/en unknown
- 1984-03-13 ES ES530548A patent/ES530548A0/en active Granted
- 1984-03-13 FI FI841008A patent/FI841008A/en not_active Application Discontinuation
- 1984-03-13 NO NO840960A patent/NO840960L/en unknown
- 1984-03-13 HU HU841001A patent/HU190530B/en unknown
- 1984-03-13 CH CH1244/84A patent/CH658247A5/en not_active IP Right Cessation
- 1984-03-13 SE SE8401398A patent/SE8401398L/en not_active Application Discontinuation
- 1984-03-13 FR FR8403835A patent/FR2542743B1/en not_active Expired
- 1984-03-14 DD DD84260892A patent/DD216932A5/en unknown
- 1984-03-14 IT IT20049/84A patent/IT1173442B/en active
- 1984-03-14 LU LU85249A patent/LU85249A1/en unknown
- 1984-03-14 PL PL24666384A patent/PL246663A1/en unknown
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