JPH0237327B2 - - Google Patents

Info

Publication number
JPH0237327B2
JPH0237327B2 JP57085619A JP8561982A JPH0237327B2 JP H0237327 B2 JPH0237327 B2 JP H0237327B2 JP 57085619 A JP57085619 A JP 57085619A JP 8561982 A JP8561982 A JP 8561982A JP H0237327 B2 JPH0237327 B2 JP H0237327B2
Authority
JP
Japan
Prior art keywords
indolamine
sustained release
mixture
coating
pellets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57085619A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57197212A (en
Inventor
Seedo Matsuharu Aametsudo
Sutefuan Homuzu Deibitsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Publication of JPS57197212A publication Critical patent/JPS57197212A/ja
Publication of JPH0237327B2 publication Critical patent/JPH0237327B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
JP57085619A 1981-05-21 1982-05-19 Durable releasing medicinal composition Granted JPS57197212A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8115678 1981-05-21

Publications (2)

Publication Number Publication Date
JPS57197212A JPS57197212A (en) 1982-12-03
JPH0237327B2 true JPH0237327B2 (enExample) 1990-08-23

Family

ID=10521980

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57085619A Granted JPS57197212A (en) 1981-05-21 1982-05-19 Durable releasing medicinal composition

Country Status (16)

Country Link
US (1) US4524060A (enExample)
EP (1) EP0067539B1 (enExample)
JP (1) JPS57197212A (enExample)
AT (1) ATE15599T1 (enExample)
AU (1) AU556241B2 (enExample)
CA (1) CA1165246A (enExample)
DE (1) DE3266332D1 (enExample)
DK (1) DK154263C (enExample)
ES (1) ES8302456A1 (enExample)
GR (1) GR76391B (enExample)
IE (1) IE53118B1 (enExample)
IL (1) IL65706A (enExample)
NZ (1) NZ200519A (enExample)
PH (1) PH19109A (enExample)
PT (1) PT74946B (enExample)
ZA (1) ZA822995B (enExample)

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US4794001A (en) * 1986-03-04 1988-12-27 American Home Products Corporation Formulations providing three distinct releases
US4904476A (en) * 1986-03-04 1990-02-27 American Home Products Corporation Formulations providing three distinct releases
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US4752470A (en) * 1986-11-24 1988-06-21 Mehta Atul M Controlled release indomethacin
CA1308357C (en) * 1987-01-28 1992-10-06 Tohru Chiba Method for the preparation of a coated solid medicament
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5084287A (en) * 1990-03-15 1992-01-28 Warner-Lambert Company Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat
ATE118345T1 (de) * 1990-08-07 1995-03-15 Pfizer Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen.
US5760093A (en) * 1991-02-27 1998-06-02 Boehringer Ingelheim Kg Halohydrocarbon-free delayed release lacquer solution for pharmaceutical preparation
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5328697A (en) * 1992-02-10 1994-07-12 Mallinckrodt Veterinary, Inc. Compositions and processes for the sustained release of drugs
US5376384A (en) * 1992-12-23 1994-12-27 Kinaform Technology, Inc. Delayed, sustained-release pharmaceutical preparation
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US20030100532A1 (en) * 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
DE69932154T2 (de) 1998-02-12 2007-05-31 G.D. Searle Llc, Chicago Verwendung von n-substituirten-1,5-dideoxy-1,5-imino-d-glucitolen zur behandlung von hepatitis infektionen
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
US7122207B2 (en) 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA69413C2 (uk) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
UA73092C2 (uk) 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
US8293277B2 (en) * 1998-10-01 2012-10-23 Alkermes Pharma Ireland Limited Controlled-release nanoparticulate compositions
US20080213378A1 (en) * 1998-10-01 2008-09-04 Elan Pharma International, Ltd. Nanoparticulate statin formulations and novel statin combinations
EP2266542A3 (en) * 1998-10-01 2013-07-31 Elan Pharma International Limited Controlled release nanoparticulate compositions
US8236352B2 (en) * 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
US20040013613A1 (en) * 2001-05-18 2004-01-22 Jain Rajeev A Rapidly disintegrating solid oral dosage form
US6428814B1 (en) * 1999-10-08 2002-08-06 Elan Pharma International Ltd. Bioadhesive nanoparticulate compositions having cationic surface stabilizers
US20040141925A1 (en) * 1998-11-12 2004-07-22 Elan Pharma International Ltd. Novel triamcinolone compositions
US6432448B1 (en) * 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
ATE402701T1 (de) * 1999-02-12 2008-08-15 United Therapeutics Corp N-(8,8,8-trifluorooctyl)-1,5-dideoxy-1,5-imino- - glucitol zur behandlung von hepatitis-virus- infektionen
JP2003505501A (ja) 1999-02-12 2003-02-12 ジー・ディー・サール・アンド・カンパニー 肝炎ウィルス感染の処置のためのグルカミン化合物
US20040115134A1 (en) * 1999-06-22 2004-06-17 Elan Pharma International Ltd. Novel nifedipine compositions
US20040258750A1 (en) * 1999-06-28 2004-12-23 Gerard Alaux Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof
EP1064938A1 (en) * 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
JP2003522791A (ja) * 2000-02-14 2003-07-29 ファルマシア コーポレイション 肝炎ウイルス感染症治療用ｎ‐置換‐１，５‐ジデオキシ‐１，５‐イミノ‐ｄ‐グルシトール化合物の使用
US20040156872A1 (en) * 2000-05-18 2004-08-12 Elan Pharma International Ltd. Novel nimesulide compositions
US7198795B2 (en) 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
BR0115585A (pt) 2000-11-28 2005-12-13 Fmc Corp Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento
CA2434169C (en) * 2001-01-12 2011-03-15 Sun Pharmaceutical Industries Limited Spaced drug delivery system
CA2443632C (en) * 2001-04-10 2011-05-03 Sun Pharmaceutical Industries Limited Timed pulse release composition
US20040101566A1 (en) * 2002-02-04 2004-05-27 Elan Pharma International Limited Novel benzoyl peroxide compositions
EP1471887B1 (en) * 2002-02-04 2010-04-21 Elan Pharma International Ltd. Nanoparticulate compositions having lysozyme as a surface stabilizer
DE60323482D1 (de) 2002-05-06 2008-10-23 Massachusetts Inst Technology Diffusionskontrollierte arzneiform sowie herstellungsmethode mittels dreidimensionalem drucken
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20060020044A1 (en) * 2004-07-26 2006-01-26 Roger Berlin Methods and compositions for treating or preventing macular-degeneration related disorders
EP2143424A4 (en) * 2007-03-26 2013-07-31 Teikoku Seiyaku Kk ORAL PHARMACEUTICAL PREPARATION FOR SPECIFIC DELIVERY TO THE COLON
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
NZ759468A (en) 2017-05-26 2026-03-27 Animal Microbiome Analytics Inc Products and methods for therapeutic administration of microorganisms to non-human animals
US20240124857A1 (en) 2021-02-19 2024-04-18 Dupont Nutrition Biosciences Aps Composition for gut health
WO2024040043A1 (en) 2022-08-16 2024-02-22 International N&H Denmark Aps Expression systems for phosphatases
US20260092088A1 (en) 2022-09-20 2026-04-02 International N&H Denmark Aps Variant anti-viral polypeptides
WO2025064636A1 (en) 2023-09-20 2025-03-27 Danisco Us Inc. Composition comprising an atp degrading enzyme and uses thereof
WO2025080755A1 (en) 2023-10-13 2025-04-17 Nutrition & Biosciences USA 4, Inc. Methods and compositions for aging and mitochondrial health

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US3034911A (en) * 1959-03-25 1962-05-15 Nat Starch Chem Corp Tablet disintegrants
FR1347413A (fr) * 1963-01-29 1963-12-27 Italnysco S P A Sphérules ou globules à action étalée et procédé pour leur préparation
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
DE1467792A1 (de) * 1965-05-21 1968-12-12 Brunnengraeber & Co Gmbh Dr Ch Sprengmittel fuer pharmazeutische Presslinge
DE2200778B2 (de) * 1971-01-13 1974-04-18 Sandoz Ag, Basel (Schweiz) Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen
DE2244558A1 (de) * 1971-08-28 1974-04-04 Degussa Arzneimittel mit ulcusheilender wirkung
DE2336218C3 (de) * 1973-07-17 1985-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Orale Arzneiform
GB1533243A (en) * 1975-02-13 1978-11-22 Wellcome Found Tablet formulation
US4097606A (en) * 1975-10-08 1978-06-27 Bristol-Myers Company APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same
JPS539315A (en) * 1976-07-09 1978-01-27 Asahi Chem Ind Co Ltd Preparation of hardly soluble pharmaceuticals
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
DE2802114A1 (de) * 1978-01-19 1979-07-26 Sandoz Ag Neue pharmazeutische zusammensetzung und verfahren zu deren herstellung
GB1584130A (en) * 1978-05-30 1981-02-04 Wyeth John & Brother Ltd Indole derivatives
JPS55122726A (en) * 1979-03-16 1980-09-20 Asahi Chem Ind Co Ltd Prolonged release drug composition
US4251518A (en) * 1979-07-03 1981-02-17 Ralston Purina Company Method of preparing readily disintegrable pharmaceutical compositions
US4309404A (en) * 1979-08-09 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
US4304773A (en) * 1980-06-26 1981-12-08 E. R. Squibb & Sons, Inc. Novel bendroflumethiazide formulations and method

Also Published As

Publication number Publication date
ZA822995B (en) 1983-12-28
EP0067539A2 (en) 1982-12-22
PH19109A (en) 1986-01-06
ES512393A0 (es) 1983-02-01
CA1165246A (en) 1984-04-10
EP0067539A3 (en) 1983-04-27
EP0067539B1 (en) 1985-09-18
GR76391B (enExample) 1984-08-10
DK228682A (da) 1982-11-22
PT74946B (en) 1983-12-23
ES8302456A1 (es) 1983-02-01
ATE15599T1 (de) 1985-10-15
AU8355482A (en) 1982-11-25
IL65706A (en) 1985-07-31
JPS57197212A (en) 1982-12-03
PT74946A (en) 1982-06-01
NZ200519A (en) 1985-08-30
AU556241B2 (en) 1986-10-30
DK154263C (da) 1989-03-28
DK154263B (da) 1988-10-31
DE3266332D1 (en) 1985-10-24
IE821213L (en) 1982-11-21
IE53118B1 (en) 1988-07-06
US4524060A (en) 1985-06-18

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