DK154263C - Fremgangsmaade til fremstilling af et farmaceutisk indoraminpraeparat med langvarig frigivelse og indeholdende et vandkanaldannelsesmiddel - Google Patents
Fremgangsmaade til fremstilling af et farmaceutisk indoraminpraeparat med langvarig frigivelse og indeholdende et vandkanaldannelsesmiddelInfo
- Publication number
- DK154263C DK154263C DK228682A DK228682A DK154263C DK 154263 C DK154263 C DK 154263C DK 228682 A DK228682 A DK 228682A DK 228682 A DK228682 A DK 228682A DK 154263 C DK154263 C DK 154263C
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- indoramine
- pharmaceutical
- procedure
- long
- Prior art date
Links
- JXZZEXZZKAWDSP-UHFFFAOYSA-N 3-(2-(4-Benzamidopiperid-1-yl)ethyl)indole Chemical compound C1CN(CCC=2C3=CC=CC=C3NC=2)CCC1NC(=O)C1=CC=CC=C1 JXZZEXZZKAWDSP-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 229960002056 indoramin Drugs 0.000 title abstract 2
- 230000007774 longterm Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000013268 sustained release Methods 0.000 abstract 3
- 239000012730 sustained-release form Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008188 pellet Substances 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8115678 | 1981-05-21 | ||
| GB8115678 | 1981-05-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK228682A DK228682A (da) | 1982-11-22 |
| DK154263B DK154263B (da) | 1988-10-31 |
| DK154263C true DK154263C (da) | 1989-03-28 |
Family
ID=10521980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK228682A DK154263C (da) | 1981-05-21 | 1982-05-19 | Fremgangsmaade til fremstilling af et farmaceutisk indoraminpraeparat med langvarig frigivelse og indeholdende et vandkanaldannelsesmiddel |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4524060A (enExample) |
| EP (1) | EP0067539B1 (enExample) |
| JP (1) | JPS57197212A (enExample) |
| AT (1) | ATE15599T1 (enExample) |
| AU (1) | AU556241B2 (enExample) |
| CA (1) | CA1165246A (enExample) |
| DE (1) | DE3266332D1 (enExample) |
| DK (1) | DK154263C (enExample) |
| ES (1) | ES512393A0 (enExample) |
| GR (1) | GR76391B (enExample) |
| IE (1) | IE53118B1 (enExample) |
| IL (1) | IL65706A (enExample) |
| NZ (1) | NZ200519A (enExample) |
| PH (1) | PH19109A (enExample) |
| PT (1) | PT74946B (enExample) |
| ZA (1) | ZA822995B (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS604120A (ja) * | 1983-06-22 | 1985-01-10 | Shionogi & Co Ltd | 作用持続型ピナシジル製剤 |
| HU190619B (en) * | 1983-11-11 | 1986-09-29 | Bezzegh,Denes,Hu | Process for producing tablets with controlled dissolution of active ingredients |
| US4728512A (en) * | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
| US4764375A (en) * | 1985-09-11 | 1988-08-16 | Kv Pharmaceutical Company | Sachet drug delivery system |
| US4904476A (en) * | 1986-03-04 | 1990-02-27 | American Home Products Corporation | Formulations providing three distinct releases |
| US4794001A (en) * | 1986-03-04 | 1988-12-27 | American Home Products Corporation | Formulations providing three distinct releases |
| US5075109A (en) * | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US6024983A (en) * | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
| US4752470A (en) * | 1986-11-24 | 1988-06-21 | Mehta Atul M | Controlled release indomethacin |
| CA1308357C (en) * | 1987-01-28 | 1992-10-06 | Tohru Chiba | Method for the preparation of a coated solid medicament |
| US5035891A (en) * | 1987-10-05 | 1991-07-30 | Syntex (U.S.A.) Inc. | Controlled release subcutaneous implant |
| US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
| US5084287A (en) * | 1990-03-15 | 1992-01-28 | Warner-Lambert Company | Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat |
| US5876752A (en) * | 1990-08-07 | 1999-03-02 | Pfizer Inc. | Use of interfacially-polymerized membranes in delivery devices |
| US5760093A (en) * | 1991-02-27 | 1998-06-02 | Boehringer Ingelheim Kg | Halohydrocarbon-free delayed release lacquer solution for pharmaceutical preparation |
| US5225202A (en) * | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
| US5968551A (en) * | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| US5328697A (en) * | 1992-02-10 | 1994-07-12 | Mallinckrodt Veterinary, Inc. | Compositions and processes for the sustained release of drugs |
| US5376384A (en) * | 1992-12-23 | 1994-12-27 | Kinaform Technology, Inc. | Delayed, sustained-release pharmaceutical preparation |
| FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
| US20030100532A1 (en) | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
| US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
| ATE331515T1 (de) | 1998-02-12 | 2006-07-15 | Searle Llc | Verwendung von n-substituirten-1,5-dideoxy-1,5- imino-d-glucitolen zur behandlung von hepatitis infektionen |
| UA69413C2 (uk) | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
| US7122207B2 (en) * | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
| UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
| US20040013613A1 (en) * | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
| US8236352B2 (en) * | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
| EP2266542A3 (en) * | 1998-10-01 | 2013-07-31 | Elan Pharma International Limited | Controlled release nanoparticulate compositions |
| US20080213378A1 (en) * | 1998-10-01 | 2008-09-04 | Elan Pharma International, Ltd. | Nanoparticulate statin formulations and novel statin combinations |
| US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US20040141925A1 (en) * | 1998-11-12 | 2004-07-22 | Elan Pharma International Ltd. | Novel triamcinolone compositions |
| US6428814B1 (en) * | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
| US6432448B1 (en) * | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
| US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
| AU3858600A (en) | 1999-02-12 | 2001-02-19 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
| ES2311921T3 (es) * | 1999-02-12 | 2009-02-16 | United Therapeutics Corporation | N-(8,8,8-trifluorooctil)1-5,-didesoxi-1,5-imino-d-glucitol para tratar infecciones por el virus de la hepatitis. |
| US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
| US20040258750A1 (en) * | 1999-06-28 | 2004-12-23 | Gerard Alaux | Timed dual release dosage forms comprising a short acting hypnotic or a salt thereof |
| EP1064938A1 (en) * | 1999-06-28 | 2001-01-03 | Sanofi-Synthelabo | Pharmaceutical dosage forms for controlled release producing at least a timed pulse |
| CN1422156A (zh) * | 2000-02-14 | 2003-06-04 | 法马西亚公司 | N-取代的-1,5-二脱氧-1,5-亚氨基-d-葡萄糖醇化合物在治疗肝炎病毒感染中的用途 |
| US20040156872A1 (en) * | 2000-05-18 | 2004-08-12 | Elan Pharma International Ltd. | Novel nimesulide compositions |
| US7198795B2 (en) * | 2000-09-21 | 2007-04-03 | Elan Pharma International Ltd. | In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions |
| TR200300731T2 (tr) | 2000-11-28 | 2004-08-23 | Fmc Corporation | Yenebilir PGA kaplama bileşimi |
| US6932861B2 (en) | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| WO2002055009A1 (en) * | 2001-01-12 | 2002-07-18 | Sun Pharmaceutical Industries Limited | Spaced drug delivery system |
| US20040156900A1 (en) * | 2001-04-10 | 2004-08-12 | Shanghvi Dilip Shantilal | Time pulsed release composition |
| JP4598399B2 (ja) * | 2002-02-04 | 2010-12-15 | エラン ファーマ インターナショナル,リミティド | 表面安定剤としてリゾチームを有するナノ粒子組成物 |
| US20040101566A1 (en) * | 2002-02-04 | 2004-05-27 | Elan Pharma International Limited | Novel benzoyl peroxide compositions |
| DE60323482D1 (de) | 2002-05-06 | 2008-10-23 | Massachusetts Inst Technology | Diffusionskontrollierte arzneiform sowie herstellungsmethode mittels dreidimensionalem drucken |
| US20060210633A1 (en) * | 2003-04-03 | 2006-09-21 | Sun Pharmaceutical Industries Limited | Programmed drug delivery system |
| US7632521B2 (en) * | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
| US20060020044A1 (en) * | 2004-07-26 | 2006-01-26 | Roger Berlin | Methods and compositions for treating or preventing macular-degeneration related disorders |
| WO2008117814A1 (ja) * | 2007-03-26 | 2008-10-02 | Teikoku Seiyaku Co., Ltd. | 大腸送達用経口製剤 |
| US20080260823A1 (en) * | 2007-04-20 | 2008-10-23 | Sciele Pharma, Inc. | Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea |
| JP7426168B2 (ja) | 2017-05-26 | 2024-02-01 | アニマル マイクロバイオーム アナリティクス インコーポレイテッド | 非ヒト動物への微生物の治療的投与用の生成物及び方法 |
| EP4294427A1 (en) | 2021-02-19 | 2023-12-27 | DuPont Nutrition Biosciences ApS | Compositions for gut health |
| WO2024040043A1 (en) | 2022-08-16 | 2024-02-22 | International N&H Denmark Aps | Expression systems for phosphatases |
| EP4590319A1 (en) | 2022-09-20 | 2025-07-30 | International N&H Denmark ApS | Variant anti-viral polypeptides |
| AU2024344435A1 (en) | 2023-09-20 | 2026-02-19 | Danisco Us Inc. | Composition comprising an atp degrading enzyme and uses thereof |
| AU2024360371A1 (en) | 2023-10-13 | 2026-02-26 | Danisco Usa Inc. | Methods and compositions for aging and mitochondrial health |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3034911A (en) * | 1959-03-25 | 1962-05-15 | Nat Starch Chem Corp | Tablet disintegrants |
| FR1347413A (fr) * | 1963-01-29 | 1963-12-27 | Italnysco S P A | Sphérules ou globules à action étalée et procédé pour leur préparation |
| US3238215A (en) * | 1963-10-17 | 1966-03-01 | Sterling Drug Inc | 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines |
| DE1467792A1 (de) * | 1965-05-21 | 1968-12-12 | Brunnengraeber & Co Gmbh Dr Ch | Sprengmittel fuer pharmazeutische Presslinge |
| DE2200778B2 (de) * | 1971-01-13 | 1974-04-18 | Sandoz Ag, Basel (Schweiz) | Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen |
| DE2244558A1 (de) * | 1971-08-28 | 1974-04-04 | Degussa | Arzneimittel mit ulcusheilender wirkung |
| DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
| GB1533243A (en) * | 1975-02-13 | 1978-11-22 | Wellcome Found | Tablet formulation |
| US4097606A (en) * | 1975-10-08 | 1978-06-27 | Bristol-Myers Company | APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same |
| JPS539315A (en) * | 1976-07-09 | 1978-01-27 | Asahi Chem Ind Co Ltd | Preparation of hardly soluble pharmaceuticals |
| GB1561204A (en) * | 1977-06-01 | 1980-02-13 | Ici Ltd | Sustained release pharmaceutical composition |
| DE2802114A1 (de) * | 1978-01-19 | 1979-07-26 | Sandoz Ag | Neue pharmazeutische zusammensetzung und verfahren zu deren herstellung |
| GB1584130A (en) * | 1978-05-30 | 1981-02-04 | Wyeth John & Brother Ltd | Indole derivatives |
| JPS55122726A (en) * | 1979-03-16 | 1980-09-20 | Asahi Chem Ind Co Ltd | Prolonged release drug composition |
| US4251518A (en) * | 1979-07-03 | 1981-02-17 | Ralston Purina Company | Method of preparing readily disintegrable pharmaceutical compositions |
| US4309404A (en) * | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
| US4304773A (en) * | 1980-06-26 | 1981-12-08 | E. R. Squibb & Sons, Inc. | Novel bendroflumethiazide formulations and method |
-
1982
- 1982-04-30 ZA ZA822995A patent/ZA822995B/xx unknown
- 1982-05-04 NZ NZ200519A patent/NZ200519A/en unknown
- 1982-05-05 CA CA000402287A patent/CA1165246A/en not_active Expired
- 1982-05-07 IL IL657066A patent/IL65706A/xx not_active IP Right Cessation
- 1982-05-07 GR GR68108A patent/GR76391B/el unknown
- 1982-05-10 AU AU83554/82A patent/AU556241B2/en not_active Expired
- 1982-05-18 AT AT82302522T patent/ATE15599T1/de active
- 1982-05-18 DE DE8282302522T patent/DE3266332D1/de not_active Expired
- 1982-05-18 EP EP82302522A patent/EP0067539B1/en not_active Expired
- 1982-05-19 JP JP57085619A patent/JPS57197212A/ja active Granted
- 1982-05-19 DK DK228682A patent/DK154263C/da not_active IP Right Cessation
- 1982-05-20 IE IE1213/82A patent/IE53118B1/en not_active IP Right Cessation
- 1982-05-20 ES ES512393A patent/ES512393A0/es active Granted
- 1982-05-20 PH PH27326A patent/PH19109A/en unknown
- 1982-05-21 PT PT74946A patent/PT74946B/pt unknown
-
1983
- 1983-10-28 US US06/546,684 patent/US4524060A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT74946A (en) | 1982-06-01 |
| ZA822995B (en) | 1983-12-28 |
| EP0067539A3 (en) | 1983-04-27 |
| ES8302456A1 (es) | 1983-02-01 |
| GR76391B (enExample) | 1984-08-10 |
| CA1165246A (en) | 1984-04-10 |
| EP0067539B1 (en) | 1985-09-18 |
| ATE15599T1 (de) | 1985-10-15 |
| IE821213L (en) | 1982-11-21 |
| EP0067539A2 (en) | 1982-12-22 |
| AU8355482A (en) | 1982-11-25 |
| DK154263B (da) | 1988-10-31 |
| PH19109A (en) | 1986-01-06 |
| ES512393A0 (es) | 1983-02-01 |
| IE53118B1 (en) | 1988-07-06 |
| US4524060A (en) | 1985-06-18 |
| NZ200519A (en) | 1985-08-30 |
| DK228682A (da) | 1982-11-22 |
| PT74946B (en) | 1983-12-23 |
| JPS57197212A (en) | 1982-12-03 |
| IL65706A (en) | 1985-07-31 |
| AU556241B2 (en) | 1986-10-30 |
| DE3266332D1 (en) | 1985-10-24 |
| JPH0237327B2 (enExample) | 1990-08-23 |
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