JPH0112477B2 - - Google Patents

Info

Publication number
JPH0112477B2
JPH0112477B2 JP56018101A JP1810181A JPH0112477B2 JP H0112477 B2 JPH0112477 B2 JP H0112477B2 JP 56018101 A JP56018101 A JP 56018101A JP 1810181 A JP1810181 A JP 1810181A JP H0112477 B2 JPH0112477 B2 JP H0112477B2
Authority
JP
Japan
Prior art keywords
plasmid
pcg1
corynebacterium glutamicum
molecular weight
plasmid pcg1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56018101A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57134500A (en
Inventor
Ryoichi Katsumata
Akira Furuya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP56018101A priority Critical patent/JPS57134500A/ja
Priority to CA000395976A priority patent/CA1196588A/en
Priority to DE198282101018T priority patent/DE58889T1/de
Priority to DE8282101018T priority patent/DE3274561D1/de
Priority to EP82101018A priority patent/EP0058889B1/en
Publication of JPS57134500A publication Critical patent/JPS57134500A/ja
Priority to US06/573,591 priority patent/US4617267A/en
Publication of JPH0112477B2 publication Critical patent/JPH0112477B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP56018101A 1981-02-12 1981-02-12 Plasmid pcg1 Granted JPS57134500A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP56018101A JPS57134500A (en) 1981-02-12 1981-02-12 Plasmid pcg1
CA000395976A CA1196588A (en) 1981-02-12 1982-02-10 Plasmid pcg1
DE198282101018T DE58889T1 (de) 1981-02-12 1982-02-11 Plasmid pcg1.
DE8282101018T DE3274561D1 (en) 1981-02-12 1982-02-11 Plasmid pcg1
EP82101018A EP0058889B1 (en) 1981-02-12 1982-02-11 Plasmid pcg1
US06/573,591 US4617267A (en) 1981-02-12 1984-01-25 Plasmid pCG1 from Corynebacterium glutamicum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56018101A JPS57134500A (en) 1981-02-12 1981-02-12 Plasmid pcg1

Publications (2)

Publication Number Publication Date
JPS57134500A JPS57134500A (en) 1982-08-19
JPH0112477B2 true JPH0112477B2 (Direct) 1989-03-01

Family

ID=11962230

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56018101A Granted JPS57134500A (en) 1981-02-12 1981-02-12 Plasmid pcg1

Country Status (5)

Country Link
US (1) US4617267A (Direct)
EP (1) EP0058889B1 (Direct)
JP (1) JPS57134500A (Direct)
CA (1) CA1196588A (Direct)
DE (2) DE3274561D1 (Direct)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778762A (en) * 1980-04-17 1988-10-18 Ajinomoto Company Incorporated Plasmid
JPS5877895A (ja) * 1981-11-02 1983-05-11 Ajinomoto Co Inc プラスミドｐｈｍ１５１９
JPS58126789A (ja) * 1981-12-29 1983-07-28 Kyowa Hakko Kogyo Co Ltd レースレオニンの製造法
US5236831A (en) * 1981-12-29 1993-08-17 Kiowa Hakko Kogyo Co., Ltd. Amino acid synthesis in corynebacteria using E. coli genes
US4559308A (en) * 1983-01-27 1985-12-17 Stauffer Chemical Co. Corynebacterium plasmid and vector
JPS59156294A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
JPS6066989A (ja) * 1983-09-24 1985-04-17 Kyowa Hakko Kogyo Co Ltd Ｌ−アルギニンの製造法
JPS59156292A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd トリプトフアンの製造法
JPS59196098A (ja) * 1983-04-23 1984-11-07 Ajinomoto Co Inc 発酵法によるｌ−トリプトフアンの製造法
US4649119A (en) * 1983-04-28 1987-03-10 Massachusetts Institute Of Technology Cloning systems for corynebacterium
JPH0783714B2 (ja) * 1983-08-29 1995-09-13 味の素株式会社 発酵法によるｌ―アミノ酸の製造法
JPH06102029B2 (ja) * 1984-07-31 1994-12-14 味の素株式会社 Ｌ−トリプトフアンの製造法
GB2165546B (en) * 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE3576523D1 (de) * 1984-11-20 1990-04-19 Ajinomoto Kk Rekombinante dna enthaltende coryneformbakterien und verfahren zur herstellung von aromatischen aminosaeuren unter verwendung dieser bakterien.
JP2967996B2 (ja) 1989-06-06 1999-10-25 協和醗酵工業株式会社 Ｌ―トリプトファンの製造法
DE69111271T2 (de) * 1990-03-08 1996-02-22 Ensuiko Sugar Refining Verfahren zur Herstellung eines Pulvers/mit erhöhtem Gehalt an Lactosucrose und Verwendung dieses Pulvers.
JP3078312B2 (ja) * 1990-11-22 2000-08-21 協和醗酵工業株式会社 物質の製造法
JPH06225776A (ja) * 1992-12-07 1994-08-16 Kyowa Hakko Kogyo Co Ltd リボフラビンの製造法
EP0644200B1 (en) * 1993-01-13 1998-04-29 Ajinomoto Co., Inc. Cell surface protein from brevibacterium lactofermentum
US6855516B1 (en) * 1998-09-04 2005-02-15 Kyowa Hakko Kogyo, Co., Ltd. Gene conferring lysozyme insensitivity to corynebacterium
EP1263963A2 (en) 1999-06-25 2002-12-11 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production
JP2003512024A (ja) 1999-07-01 2003-04-02 ビーエーエスエフ アクチェンゲゼルシャフト ホスホエノールピルビン酸：糖ホスホトランスフェラーゼ系タンパク質をコードするコリネバクテリウム−グルタミカム遺伝子
EP1702980A1 (en) 1999-07-01 2006-09-20 Basf Aktiengesellschaft Corynebacterium glutamicum gene encoding Hpr of phosphoenolpyruvate:sugar phosphotransferase system
PL341895A1 (en) 1999-08-12 2001-02-26 Ajinomoto Kk Plasmide autonomously replicable in corynebacter bacteria
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
JP4469568B2 (ja) 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
WO2005021770A1 (ja) 2003-08-28 2005-03-10 Mitsubishi Chemical Corporation コハク酸の製造方法
CN1989238B (zh) 2004-05-20 2010-05-26 味之素株式会社 生产琥珀酸的细菌和生产琥珀酸的方法
JP5572279B2 (ja) * 2004-05-20 2014-08-13 味の素株式会社 コハク酸生産菌及びコハク酸の製造方法
CN101072864A (zh) * 2004-12-06 2007-11-14 赛格生物科学有限公司 可将生物活性化合物递送到反刍动物肠道的细菌的培养方法
CN103468758B (zh) 2004-12-28 2015-10-28 味之素株式会社 产生l-谷氨酸的微生物和产生l-谷氨酸的方法
JP5088136B2 (ja) 2005-10-18 2012-12-05 味の素株式会社 コハク酸の製造方法
CN101336292B (zh) 2005-12-27 2013-09-11 协和发酵生化株式会社 用于生产l-谷氨酰胺的方法
WO2007099867A1 (ja) 2006-02-24 2007-09-07 Mitsubishi Chemical Corporation 有機酸生産菌及び有機酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
JP5493854B2 (ja) 2007-04-10 2014-05-14 味の素株式会社 有機酸の製造方法
WO2008133131A1 (ja) 2007-04-16 2008-11-06 Ajinomoto Co., Inc. 有機酸の製造方法
CN101821399A (zh) 2007-08-23 2010-09-01 三菱化学株式会社 琥珀酸的制备方法
WO2009031565A1 (ja) 2007-09-04 2009-03-12 Ajinomoto Co., Inc. アミノ酸生産微生物及びアミノ酸の製造法
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
US8530203B2 (en) 2008-09-01 2013-09-10 Shinshu University Process for producing useful substance
CN102272304B (zh) 2009-01-07 2013-10-23 三菱化学株式会社 切断固醇侧链的酶蛋白质及其应用
WO2010095642A1 (ja) 2009-02-18 2010-08-26 国立大学法人信州大学 有用物質の製造方法
EP2415860A4 (en) 2009-03-30 2012-09-05 Res Inst Innovative Tech Earth CORNEFORMED BACTERIUM TRANSFORMANT, AND METHOD FOR PRODUCING ISOBUTANOL USING THE SAME
JP2012223091A (ja) 2009-08-25 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
WO2012029819A1 (ja) 2010-08-31 2012-03-08 株式会社エーピーアイ コーポレーション 新規加水分解酵素タンパク質
KR101842518B1 (ko) 2010-09-08 2018-03-27 그린 페놀 가이하쓰 가부시키가이샤 코리네형 세균 형질 전환체 및 그것을 사용하는 페놀의 제조 방법
WO2012063862A1 (ja) 2010-11-10 2012-05-18 グリーンフェノール・高機能フェノール樹脂製造技術研究組合 コリネ型細菌形質転換体及びそれを用いるフェノールの製造方法
WO2012128231A1 (ja) 2011-03-18 2012-09-27 三菱化学株式会社 ポリマーの製造方法、有機酸の製造方法及び有機酸生産菌
JP5960701B2 (ja) 2011-08-22 2016-08-02 公益財団法人地球環境産業技術研究機構 コリネ型細菌形質転換体及びそれを用いるバリンの製造方法
AU2012329967B2 (en) 2011-10-25 2015-07-23 Ajinomoto Co., Inc. Secretion production method for protein
IN2014CN04039A (Direct) 2011-11-02 2015-10-23 Ajinomoto Kk
EP2774982B1 (en) 2011-11-02 2017-06-21 Ajinomoto Co., Inc. Method for secreting and producing proteins
KR20140091742A (ko) 2011-11-11 2014-07-22 아지노모토 가부시키가이샤 발효법에 의한 목적 물질의 제조법
EP2857510A4 (en) 2012-05-29 2016-02-10 Ajinomoto Kk PROCESS FOR PREPARING 3-ACETYLAMINO-4-HYDROXYBENZOIC ACID
EP2860259B1 (en) 2013-02-18 2016-11-09 Ajinomoto Co., Inc. Method for producing protein by precipitation
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
EP2868745B1 (en) 2013-05-13 2017-06-21 Ajinomoto Co., Inc. Method for manufacturing an L-amino acid
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
WO2015060391A1 (ja) 2013-10-23 2015-04-30 味の素株式会社 目的物質の製造法
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JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
CA2985279A1 (en) 2015-05-19 2016-11-24 Lucite International Uk Limited Process for the biological production of methacrylic acid and derivatives thereof
WO2017073701A2 (en) 2015-10-27 2017-05-04 Ajinomoto Co., Inc. Method for producing aldehyde
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系ｌ−アミノ酸の製造法
WO2017122747A1 (en) 2016-01-12 2017-07-20 Ajinomoto Co., Inc. Method for producing benzaldehyde
JP7021639B2 (ja) 2016-10-21 2022-02-17 味の素株式会社 タンパク質の分泌生産法
KR102337932B1 (ko) 2016-10-21 2021-12-13 아지노모토 가부시키가이샤 단백질의 분비 생산법
JP2019531759A (ja) 2016-10-26 2019-11-07 味の素株式会社 目的物質の製造方法
EP3532631A1 (en) 2016-10-26 2019-09-04 Ajinomoto Co., Inc. Method for producing l-methionine or metabolites requiring s-adenosylmethionine for synthesis
CN109890972B (zh) 2016-10-26 2022-11-08 味之素株式会社 生产目标物质的方法
CN109890970B (zh) 2016-10-26 2023-04-04 味之素株式会社 生产目标物质的方法
JP2019536449A (ja) 2016-10-26 2019-12-19 味の素株式会社 目的物質の製造方法
EP3532610B1 (en) 2016-10-27 2023-09-27 Ajinomoto Co., Inc. Method for producing aldehyde
GB201619827D0 (en) 2016-11-23 2017-01-04 Lucite Int Uk Ltd Process for the production of methyl methacrylate
JP7613833B2 (ja) 2017-03-28 2025-01-15 味の素株式会社 Ｒｎａの製造方法
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 Ｌ－アミノ酸の製造法
JP7035024B2 (ja) 2017-04-13 2022-03-14 協和発酵バイオ株式会社 テアニンの製造方法
US10858676B2 (en) 2017-05-22 2020-12-08 Ajinomoto Co., Inc. Method for producing objective substance
WO2019059404A1 (ja) 2017-09-25 2019-03-28 味の素株式会社 タンパク質の製造法および二糖の製造法
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
US11680279B2 (en) 2017-11-29 2023-06-20 Ajinomoto Co., Inc. Method for producing objective substance
WO2019130723A1 (en) 2017-12-26 2019-07-04 Ajinomoto Co., Inc. Method of producing glycine by fermentation
WO2019163827A1 (ja) 2018-02-20 2019-08-29 味の素株式会社 Ｒｎａサイレンシングを誘導する方法
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EP3783106A4 (en) 2018-04-20 2022-01-05 Ajinomoto Co., Inc. PROCESS FOR THE SECRETION OF A PROTEIN
WO2020027251A1 (en) 2018-08-03 2020-02-06 Ajinomoto Co., Inc. Method for producing objective substance
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BR112021002300A2 (pt) 2018-08-10 2021-05-04 Kyowa Hakko Bio Co., Ltd microrganismo que produz ácido eicosapentaenoico e método para a produção de ácido eicosapentaenoico
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EP4053287A4 (en) 2019-10-28 2023-11-01 Ajinomoto Co., Inc. Benzaldehyde production method
EP4079862A4 (en) 2019-12-16 2024-01-17 Kyowa Hakko Bio Co., Ltd. MICROORGANISM HAVING MODIFIED LACTOSE PERMEASE, AND METHOD FOR PRODUCING LACTOSE-CONTAINING OLIGOSACCHARIDE
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WO2022092018A1 (ja) 2020-10-28 2022-05-05 味の素株式会社 Ｌ－アミノ酸の製造法
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AU2022306337A1 (en) 2021-07-07 2024-02-01 Ajinomoto Co., Inc. Method for secretory production of unnatural-amino-acid-containing protein
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WO2023210244A1 (ja) 2022-04-28 2023-11-02 協和発酵バイオ株式会社 Ｎａｍｐｔ活性を有する蛋白質およびｎｍｎの製造方法
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JPWO2024005155A1 (Direct) 2022-06-30 2024-01-04
GB2621337A (en) 2022-08-08 2024-02-14 Mitsubishi Chemical Uk Ltd Process for the biological production of methacrylic acid and derivatives thereof
JPWO2024122636A1 (Direct) 2022-12-09 2024-06-13
WO2025005153A1 (ja) 2023-06-29 2025-01-02 キリンホールディングス株式会社 ４－（アミノメチル）シクロヘキサン－１－カルボン酸の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3003925A (en) * 1956-05-17 1961-10-10 Kyowa Hakko Kogyo Kk Method of producing l-glutamic acid by fermentation
US3002889A (en) * 1960-06-20 1961-10-03 Kyowa Hakko Kogyo Kk Method of producing l-glutamic acid
US3220929A (en) * 1964-02-10 1965-11-30 Kyowa Hakko Kogyo Kk Microbiological production of amino acid by reductive amination
GB2052516B (en) * 1979-06-01 1983-06-29 Searle & Co Plasmid vectors production and use thereof
JPS57183799A (en) * 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid

Also Published As

Publication number Publication date
JPS57134500A (en) 1982-08-19
DE3274561D1 (en) 1987-01-15
CA1196588A (en) 1985-11-12
EP0058889B1 (en) 1986-12-03
US4617267A (en) 1986-10-14
EP0058889A1 (en) 1982-09-01
DE58889T1 (de) 1983-04-14

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