JP7678753B2 - 受容体チロシンキナーゼ様オーファン受容体1(ror1)に特異的な抗体およびキメラ抗原受容体 - Google Patents

受容体チロシンキナーゼ様オーファン受容体1(ror1)に特異的な抗体およびキメラ抗原受容体 Download PDF

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JP7678753B2
JP7678753B2 JP2021544129A JP2021544129A JP7678753B2 JP 7678753 B2 JP7678753 B2 JP 7678753B2 JP 2021544129 A JP2021544129 A JP 2021544129A JP 2021544129 A JP2021544129 A JP 2021544129A JP 7678753 B2 JP7678753 B2 JP 7678753B2
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cdr
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ror1
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アンドレイア コスタ
ルペシュ アミン
ジェンナ バイリー
サムリティ ベディ
ブライアン ベルモント
アイ チェン
スティーブン ジェイコブ ゴールドフレス
エリック ジェフリー
ユエ ジャン
ヨンジュー オー
メイドリン ウィリアムズ
コリン ホーキンス
キャサリン シエラ
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ジュノー セラピューティクス インコーポレイテッド
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JP2021544129A 2019-01-29 2020-01-28 受容体チロシンキナーゼ様オーファン受容体1(ror1)に特異的な抗体およびキメラ抗原受容体 Active JP7678753B2 (ja)

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US201962798456P 2019-01-29 2019-01-29
US62/798,456 2019-01-29
PCT/US2020/015489 WO2020160050A1 (en) 2019-01-29 2020-01-28 Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)

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JP2022518925A JP2022518925A (ja) 2022-03-17
JP2022518925A5 JP2022518925A5 (https=) 2023-02-06
JPWO2020160050A5 JPWO2020160050A5 (https=) 2023-02-06
JP7678753B2 true JP7678753B2 (ja) 2025-05-16

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US (2) US12268741B2 (https=)
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AU (1) AU2020215576A1 (https=)
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JP6865688B2 (ja) 2015-01-16 2021-04-28 ジュノー セラピューティクス インコーポレイテッド Ror1に特異的な抗体およびキメラ抗原受容体
JP7447006B2 (ja) * 2017-11-01 2024-03-11 ジュノー セラピューティクス インコーポレイテッド B細胞成熟抗原(bcma)に特異的なキメラ抗原受容体
SG11202003427XA (en) 2017-11-06 2020-05-28 Juno Therapeutics Inc Combination of a cell therapy and a gamma secretase inhibitor
WO2019113557A1 (en) 2017-12-08 2019-06-13 Juno Therapeutics, Inc. Process for producing a composition of engineered t cells
KR20210113169A (ko) 2018-11-01 2021-09-15 주노 쎄러퓨티크스 인코퍼레이티드 Β세포 성숙 항원에 특이적인 키메라 항원 수용체를 이용한 치료 방법
CA3123303A1 (en) 2019-01-29 2020-08-06 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for receptor tyrosine kinase like orphan receptor 1 (ror1)
WO2022029660A1 (en) * 2020-08-05 2022-02-10 Juno Therapeutics, Inc. Anti-idiotypic antibodies to ror1-targeted binding domains and related compositions and methods
KR20230053602A (ko) * 2020-08-24 2023-04-21 에피맙 바이오테라퓨틱스 (에이치케이) 리미티드 항-ror1 항체 및 관련된 이중특이적 결합 단백질
JP2023549780A (ja) 2020-11-04 2023-11-29 ジュノー セラピューティクス インコーポレイテッド 改変されたインバリアントcd3免疫グロブリンスーパーファミリー鎖遺伝子座からキメラ受容体を発現する細胞ならびに関連するポリヌクレオチドおよび方法
JP2024500093A (ja) * 2020-12-10 2024-01-04 ウーシー バイオロジクス アイルランド リミテッド P-カドヘリンに対する抗体及びその使用
US20240415883A1 (en) * 2021-02-01 2024-12-19 The Regents Of The University Of California Treatment of neuroendocrine cancers
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
JP2024509853A (ja) 2021-03-03 2024-03-05 ジュノー セラピューティクス インコーポレイテッド T細胞療法およびdgk阻害剤の組合せ
JP2024508597A (ja) * 2021-03-09 2024-02-28 四川科倫博泰生物医薬股▲フン▼有限公司 Ror1結合タンパク質及びその用途
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